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Seminars in cancer biology, ISSN 1044-579X, 2018, Volume 50, pp. 77 - 89
The FOXO3 and FOXM1 forkhead box transcription factors, functioning downstream of the essential PI3K-Akt, Ras-ERK and JNK/p38MAPK signalling cascades, are... 
TO-MESENCHYMAL TRANSITION | IN-VITRO | ACTIVATED PROTEIN-KINASE | STEM-LIKE CELLS | ONCOLOGY | DNA-DAMAGE RESPONSE | ESTROGEN-RECEPTOR-ALPHA | JUN NH2-TERMINAL KINASE | FOXO TRANSCRIPTION FACTORS | FORKHEAD BOX M1 | NEGATIVE BREAST-CANCER | DNA Repair - drug effects | Humans | Gene Expression Regulation, Neoplastic | Antineoplastic Agents - therapeutic use | Neoplasms - drug therapy | Cell Self Renewal - genetics | Forkhead Box Protein O3 - genetics | Drug Resistance, Neoplasm - genetics | Neoplasms - genetics | Forkhead Box Protein M1 - genetics | Cell Proliferation - drug effects | Neoplasms - pathology | Drug Resistance, Neoplasm - drug effects | Drug resistance in microorganisms | Chromatin | Endothelial growth factors | Leukemia | DNA damage | Estrogen | Disease susceptibility | Biological response modifiers | T cells | DNA repair | Epidermal growth factor | Nucleotide sequencing | Drug therapy | Protein kinases | Health aspects | Protein binding | Tyrosine | Niacinamide | Superoxide | DNA binding proteins | Cell differentiation | Chemotherapy | Multiprocessing | Gliomas | Stem cells | Interferon | Lymphomas | Adenylic acid | Mitogens | Cancer | DNA sequencing | AURKA, aurora kinase A | Fox, forkhead box | Bim, B-cell lymphoma 2 interacting mediator | EGF, epidermal growth factor | JNK | BRIP1, BRCA1-interacting protein-terminal helicase 1 | GICs, glioma-initiating cells | MCL, mantle cell lymphoma | PKB, protein kinase B | SCs, stem cells | LEF, T-cell factor | Skp2, S-phase kinase-associated protein 2 | SSBs, single-strand breaks | mTOR, mammalian target of rapamycin | NBS1, Nijmegen breakage syndrome 1 | stress activated protein kinase | MEK, mitogen-activated protein kinase kinase | PIP3, phosphatidylinositol- 3,4,5-trisphosphate | BER, base excision repair | lymphoid enhancer factor | VEGF, vascular endothelial growth factor | AML, acute myeloid leukaemia | ER+ve, estreogen receptor positive | EXO1, exonuclease 1 | EGFR, epidermal growth factor receptor | MDR1, multidrug resistance protein 1 | ChIP-seq, chromatin immunoprecipitation with massively parallel DNA sequencing | ABCB1, ATP-binding cassette sub-family B member 1 | TCF | SOD-2, superoxide dismutase | TKIs, tyrosine kinase inhibitors | PDK, phosphoinositide-dependent kinase | IFNɣ, interferon-ɣ | BRCA2, breast cancer-associated gene 2 | DDR, DNA damage response | Cks1, cyclin-dependent kinases regulatory subunit 1 | ESR1, estrogen receptor alpha gene | NHEJ, non-homologous end joining | XRCC1, X-ray cross-complementing group 1 | OTUB1, OUT domain-containing ubiquitin aldehyde-binding protein 1 | IGF, insulin growth factor | TRAIL, tumour necrosis factor-related apoptosis inducing ligand | ER, estrogen receptor | MRN, MER11-RAD50-NBS1 | BRCA1, breast cancer susceptibility gene product 1 | FasL, fas ligand | RTKs, receptor tyrosine kinases | Sox1, sex determining region Y box 2 | GADD45, DNA damage-inducible protein 45 | MMR, mismatch repair | PI3K, phosphatidylinositol 3-kinase | ROS, reactive oxygen species | NAMPT, nicotinamide-phosphribosyltransferase | miRs, Micro-RNAs | FHRE, forkhead response element | ATM, Ataxia-telangiectasia mutated | NER, nucleotide excision repair | ERK, extracellular signal-regulated kinase | HR, homologous recombination | AMPK, adenosine monophosphate-activated protein kinase | DSBs, double strands breaks | PA, Psammaplysene A | CML, chronic myeloid leukaemia | HCC, hepatocellular carcinoma | Mst1, macrophage stimulating 1 | Rb2, retinoblastoma-related p130 | SAPK, c-Jun N-terminal kinase | CSCs, cancer stem cells
Journal Article
Biology of Reproduction, ISSN 0006-3363, 02/2008, Volume 78, Issue 2, pp. 218 - 233
.... In frog and mouse oocytes, Aurora A regulates polyadenylation-dependent translation of several mRNAs such as MOS and CCNB1 , presumably by phosphorylating CPEB, and Aurora B phosphorylates histone H3 during meiosis... 
Gamete biology | Aurora kinases | Bovine | CPEB | Meiosis | Oocyte development | Kinases | Oocyte | MESSENGER-RNA TRANSLATION | meiosis | PARTHENOGENETIC ACTIVATION | MAP KINASE | oocyte development | CHROMOSOME CONDENSATION | gamete biology | REPRODUCTIVE BIOLOGY | kinases | oocyte | IN-VITRO MATURATION | CPEB PHOSPHORYLATION | II TRANSITION | MOUSE OOCYTES | GENE-EXPRESSION | bovine | XENOPUS-OOCYTES | Protein-Serine-Threonine Kinases - analysis | Nitriles - pharmacology | mRNA Cleavage and Polyadenylation Factors - metabolism | Cytoplasm - metabolism | RNA, Messenger - metabolism | Cyclin B1 | Embryo, Mammalian - metabolism | Aurora Kinase A | CDC2 Protein Kinase - metabolism | Proto-Oncogene Proteins c-mos - genetics | Aurora Kinase B | Aurora Kinase C | Meiosis - drug effects | Cyclin B - genetics | Cattle | Female | Proto-Oncogene Proteins c-mos - metabolism | mRNA Cleavage and Polyadenylation Factors - genetics | Protein-Serine-Threonine Kinases - metabolism | Cytoplasm - chemistry | mRNA Cleavage and Polyadenylation Factors - analysis | Butadienes - pharmacology | CDC2 Protein Kinase - genetics | Oocytes - growth & development | Fertilization | Oocytes - metabolism | Purines - pharmacology | Metformin - pharmacology | Oocytes - chemistry | Protein-Serine-Threonine Kinases - genetics | Aurora Kinases | Piperazines - pharmacology | Proto-Oncogene Proteins c-mos - analysis | Cyclin B - analysis | Animals | Polyadenylation | CDC2 Protein Kinase - analysis | Cyclin B - metabolism | Protein Kinase Inhibitors - pharmacology | CDC2 Protein Kinase | Piperazines | Embryo, Mammalian | Protein-Serine-Threonine Kinases | Proto-Oncogene Proteins c-mos | Butadienes | Cellular Biology | Oocytes | Life Sciences | Purines | Protein Kinase Inhibitors | Cyclin B | Nitriles | Metformin | RNA, Messenger | mRNA Cleavage and Polyadenylation Factors | Cytoplasm | Reproductive Biology
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 10/2012, Volume 55, Issue 20, pp. 8721 - 8734
Journal Article
Cell cycle (Georgetown, Tex.), ISSN 1538-4101, 06/2009, Volume 8, Issue 12, pp. 1921 - 1929
Journal Article
Scientific reports, ISSN 2045-2322, 2019, Volume 9, Issue 1, pp. 18622 - 15
.... A conserved mitotic kinase, Aurora B, is activated during M-phase by association with INCENP, forming the chromosome passenger complex with Borealin and Survivin... 
IN-VITRO PHOSPHORYLATION | COMPLEX | PROTEIN | HISTONE H3 | INCENP | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | S-PHASE | CELL-CYCLE | CENP-A | DNA-REPLICATION | Aurora B protein | DNA biosynthesis | Initiation complex | Phosphorylation | Threonine | INCENP protein | Replication initiation | Paclitaxel | Protein-serine/threonine kinase | Survivin | Kinases
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2019, Volume 116, Issue 28, pp. 13937 - 13942
Journal Article
Nature reviews. Cancer, ISSN 1474-1768, 2017, Volume 17, Issue 2, pp. 93 - 115
.... Proliferation depends on progression through four distinct phases of the cell cycle G0/G1, S, G2 and M which is regulated by several cyclin-dependent kinases (CDKs... 
INVESTIGATIONAL AURORA KINASE | PHASE-II TRIAL | POLO-LIKE-KINASE | EARLY EMBRYONIC-DEVELOPMENT | DINACICLIB SCH 727965 | ADVANCED SOLID TUMORS | ONCOLOGY | PREVENTS TUMOR-GROWTH | VOLASERTIB BI 6727 | DEPENDENT KINASE INHIBITOR | SMALL-MOLECULE INHIBITOR | Cyclin-Dependent Kinase 6 - antagonists & inhibitors | Humans | Checkpoint Kinase 1 - physiology | Aurora Kinase A - antagonists & inhibitors | Cyclin-Dependent Kinase 2 - physiology | Cell Cycle Proteins - antagonists & inhibitors | Protein-Tyrosine Kinases - physiology | Aurora Kinase A - physiology | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cyclin-Dependent Kinase 4 - antagonists & inhibitors | Proto-Oncogene Proteins - antagonists & inhibitors | Signal Transduction | Protein-Serine-Threonine Kinases - physiology | Checkpoint Kinase 1 - antagonists & inhibitors | Clinical Trials as Topic | Neoplasms - drug therapy | Animals | Cyclin-Dependent Kinase 4 - physiology | Nuclear Proteins - antagonists & inhibitors | Proto-Oncogene Proteins - physiology | Cyclin-Dependent Kinase 2 - antagonists & inhibitors | Cyclin-Dependent Kinase 6 - physiology | Nuclear Proteins - physiology | Cell Cycle Proteins - physiology | Protein-Tyrosine Kinases - antagonists & inhibitors | Proteins | Care and treatment | Usage | MicroRNA | Cell cycle | Research | Cancer
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 07/2010, Volume 120, Issue 7, pp. 2563 - 2574
Journal Article