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1. Full Text Transcriptomic analysis of autistic brain reveals convergent molecular pathology
by Voineagu, Irina and Wang, Xinchen and Johnston, Patrick and Lowe, Jennifer K and Tian, Yuan and Horvath, Steve and Mill, Jonathan and Cantor, Rita M and Blencowe, Benjamin J and Geschwind, Daniel H
Nature, ISSN 0028-0836, 06/2011, Volume 474, Issue 7351, pp. 380 - 386
Autism spectrum disorder (ASD) is a common, highly heritable neurodevelopmental condition characterized by marked genetic heterogeneity(1-3). Thus, a... 
NETWORK ANALYSIS | PATHWAYS | PACKAGE | MULTIDISCIPLINARY SCIENCES | COPY NUMBER | DISEASE | SPECTRUM DISORDERS | CANDIDATE GENE | COMMON GENETIC-VARIANTS | ASSOCIATION | EXPRESSION | Autistic Disorder - genetics | RNA-Binding Proteins - genetics | Autistic Disorder - pathology | Genome-Wide Association Study | Autistic Disorder - physiopathology | Frontal Lobe - metabolism | Oligonucleotide Array Sequence Analysis | Gene Expression Regulation - genetics | Alternative Splicing - genetics | Brain - physiopathology | Frontal Lobe - physiopathology | Humans | RNA Splicing Factors | Exons - genetics | Gene Expression Profiling | Temporal Lobe - metabolism | Case-Control Studies | Brain - metabolism | Temporal Lobe - physiopathology | Brain - pathology | Transcription, Genetic - genetics | Temporal Lobe - pathology | Frontal Lobe - pathology | Autism | Genomes | Ontology | Gene expression | Index Medicus
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2. Full Text Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes
by Rubenstein, John L. R and Heintz, Nathaniel and Rosenmund, Christian and Gong, Shiaoching and Noebels, Jeffrey L and Lu, Hui-Chen and Ekker, Marc and Yoo, Jong and Chao, Hsiao-Tuan and Xue, Mingshan and Chen, Hongmei and Zoghbi, Huda Y and Samaco, Rodney C and Chahrour, Maria and Neul, Jeffrey L
Nature, ISSN 0028-0836, 11/2010, Volume 468, Issue 7321, pp. 263 - 269
Mutations in the X-linked MECP2 gene, which encodes the transcriptional regulator methyl-CpG-binding protein 2 (MeCP2), cause Rett syndrome and several... 
GLUTAMIC-ACID DECARBOXYLASE | GENE | 67 KDA | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | MUTATION | NEURONAL MECP2 | SCHIZOPHRENIA | MICE | CPG-BINDING PROTEIN-2 | YOUNG GIRLS | Autistic Disorder - physiopathology | gamma-Aminobutyric Acid - metabolism | Methyl-CpG-Binding Protein 2 - metabolism | Male | Psychomotor Disorders - complications | Methyl-CpG-Binding Protein 2 - deficiency | Compulsive Behavior - physiopathology | Neurons - metabolism | Disease Models, Animal | Autistic Disorder - genetics | Signal Transduction | Compulsive Behavior - genetics | Genotype | Mice, Transgenic | Survival Rate | Hippocampus - pathology | Rett Syndrome - physiopathology | Self-Injurious Behavior - genetics | Phenotype | Neuronal Plasticity | Long-Term Potentiation | Stereotypic Movement Disorder - genetics | Compulsive Behavior - complications | Glutamate Decarboxylase - metabolism | Mice | Hippocampus - physiopathology | Autistic Disorder - pathology | Rett Syndrome - complications | Neural Inhibition | Stereotypic Movement Disorder - pathology | Reflex, Startle - genetics | Electroencephalography | Methyl-CpG-Binding Protein 2 - genetics | Synaptic Transmission | Psychomotor Disorders - genetics | Self-Injurious Behavior - complications | Psychomotor Disorders - physiopathology | Inhibitory Postsynaptic Potentials | Stereotypic Movement Disorder - physiopathology | Brain - cytology | Homeodomain Proteins - genetics | Stereotypic Movement Disorder - complications | Self-Injurious Behavior - physiopathology | Animals | Rett Syndrome - pathology | Vesicular Inhibitory Amino Acid Transport Proteins - genetics | Presynaptic Terminals - metabolism | Autistic Disorder - complications | Respiration | Rett Syndrome - genetics | Autism | Care and treatment | Rett syndrome | Schizophrenia | GABA | Genetic aspects | Diagnosis | Cognition disorders | Seizures (Medicine) | Health aspects | Studies | Anxieties | Social interaction | Neurons | Rodents | Bipolar disorder | Behavior | Gene expression | Index Medicus
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3. Full Text Brain growth across the life span in autism: Age-specific changes in anatomical pathology
by Courchesne, Eric and Campbell, Kathleen and Solso, Stephanie
Brain Research, ISSN 0006-8993, 2010, Volume 1380, pp. 138 - 145
Abstract Autism is marked by overgrowth of the brain at the earliest ages but not at older ages when decreases in structural volumes and neuron numbers are... 
Neurology | Development | Autism | Degeneration | Overgrowth | Magnetic resonance imaging | MRI | SPECTRUM DISORDER | HEAD CIRCUMFERENCE GROWTH | INFANTILE-AUTISM | EARLY-CHILDHOOD | FRONTAL-CORTEX | 1ST YEAR | CORTICAL DEVELOPMENT | NEUROSCIENCES | CHILDREN | CEREBELLUM | Autistic Disorder - genetics | Autistic Disorder - pathology | Autistic Disorder - physiopathology | Age Factors | Brain - physiopathology | Humans | Middle Aged | Child, Preschool | Infant | Male | Brain - growth & development | Hypertrophy - pathology | Aging - pathology | Atrophy | Young Adult | Aging - genetics | Adolescent | Hypertrophy - genetics | Brain - pathology | Adult | Female | Child | Index Medicus | magnetic resonance imaging | pathology | overgrowth | degeneration
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4. Full Text Disorder-specific functional abnormalities during sustained attention in youth with Attention Deficit Hyperactivity Disorder (ADHD) and with Autism
by Christakou, A and Murphy, C.M and Chantiluke, K and Cubillo, A.I and Smith, A.B and Giampietro, V and Daly, E and Ecker, C and Robertson, D and Murphy, D.G and Rubia, K and MRC AIMS Consortium and MRC AIMS consortium
Molecular Psychiatry, ISSN 1359-4184, 02/2013, Volume 18, Issue 2, pp. 236 - 244
Attention Deficit Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD) are often comorbid and share behavioural-cognitive abnormalities in... 
ADHD | fMRI | attention | ASD | dorsolateral prefrontal cortex | PSYCHIATRY | CONDUCT DISORDER | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTERFERENCE INHIBITION | SPECTRUM DISORDERS | NEUROSCIENCES | DEFICIT/HYPERACTIVITY DISORDER | CHILDREN | EXECUTIVE FUNCTION | EVENT-RELATED FMRI | PSYCHIATRIC-DISORDERS | DYSFUNCTION | BRAIN | Psychomotor Performance | Autistic Disorder - pathology | Cerebral Cortex - blood supply | Humans | Cerebral Cortex - pathology | Male | Attention Deficit Disorder with Hyperactivity - pathology | Functional Laterality | Reaction Time - physiology | Case-Control Studies | Oxygen - blood | Neuropsychological Tests | Attention - physiology | Magnetic Resonance Imaging | Movement - physiology | Analysis of Variance | Image Processing, Computer-Assisted | Brain Mapping | Surveys and Questionnaires | Photic Stimulation | Child | Research | Comorbidity | Health aspects | Attention-deficit hyperactivity disorder | Pervasive developmental disorders | Attention | Index Medicus | Cerebellum | Autism | Cortex (prefrontal) | Vigilance | Deactivation | Intelligence | Cortex (parietal) | Attention deficit hyperactivity disorder | Brain mapping | Cognitive ability | Functional magnetic resonance imaging | Original
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5. Full Text Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits
by Tang, Guomei and Gudsnuk, Kathryn and Kuo, Sheng-Han and Cotrina, Marisa L and Rosoklija, Gorazd and Sosunov, Alexander and Sonders, Mark S and Kanter, Ellen and Castagna, Candace and Yamamoto, Ai and Yue, Zhenyu and Arancio, Ottavio and Peterson, Bradley S and Champagne, Frances and Dwork, Andrew J and Goldman, James and Sulzer, David
Neuron, ISSN 0896-6273, 09/2014, Volume 83, Issue 5, pp. 1131 - 1143
Developmental alterations of excitatory synapses are implicated in autism spectrum disorders (ASDs). Here, we report increased dendritic spine density with... 
DENDRITIC SPINES | SUPERIOR TEMPORAL SULCUS | TUBEROUS SCLEROSIS COMPLEX | NEUROPSYCHIATRIC DISORDERS | FUNCTIONAL CONNECTIVITY | MICE | AUTOPHAGY | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | MOUSE MODELS | BRAIN | Neurons - pathology | Autistic Disorder - pathology | Age Factors | TOR Serine-Threonine Kinases - metabolism | Humans | Child, Preschool | Male | Autophagy - physiology | Synapses - pathology | Autophagy - drug effects | Young Adult | Exploratory Behavior - physiology | Tumor Suppressor Proteins - deficiency | Tumor Suppressor Proteins - genetics | Female | Neurons - drug effects | Temporal Lobe - pathology | Child | Immunosuppressive Agents - pharmacology | Disease Models, Animal | Autistic Disorder - genetics | Synapses - drug effects | Mice, Transgenic | Sirolimus - pharmacology | Animals | Adolescent | Dendritic Spines - genetics | Mice | Autism | Neurosciences | Analysis | Cells | Proteins | Brain | Pathology | Child development | Protein synthesis | Neurons | Morphology | Behavior | Regression analysis | Autophagy | Age | Index Medicus
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6. Full Text Differences in White Matter Fiber Tract Development Present From 6 to 24 Months in Infants With Autism
by Wolff, Jason J and Gu, Hongbin and Gerig, Guido and Elison, Jed T and Styner, Martin and Gouttard, Sylvain and Botteron, Kelly N and Dager, Stephen R and Dawson, Geraldine and Estes, Annette M and Evans, Alan C and Hazlett, Heather C and Kostopoulos, Penelope and McKinstry, Robert C and Paterson, Sarah J and Schultz, Robert T and Zwaigenbaum, Lonnie and Piven, Joseph and IBIS Network and the IBIS Network
American Journal of Psychiatry, ISSN 0002-953X, 6/2012, Volume 169, Issue 6, pp. 589 - 600
Children who developed autism spectrum disorders (ASDs) by age 2 had greater development of cerebral white matter fiber tracts by 6 months than unaffected... 
SYNCHRONIZATION | PSYCHIATRY | EARLY-CHILDHOOD | SPECTRUM DISORDERS | BRAIN-DEVELOPMENT | DIFFUSION | SPECIALIZATION | CORTICAL DEVELOPMENT | HEAD CIRCUMFERENCE | HIGH-FUNCTIONING AUTISM | CHILDREN | Neuroimaging | Autistic Disorder - pathology | Child Development Disorders, Pervasive - pathology | Humans | Child, Preschool | Child Development Disorders, Pervasive - etiology | Infant | Male | Brain - growth & development | Case-Control Studies | Autistic Disorder - etiology | Diffusion Tensor Imaging | Magnetic Resonance Imaging | Anisotropy | Nerve Fibers, Myelinated - pathology | Brain - pathology | Female | Development | Developmental neurophysiology | Infants | Research | Growth | Autistic children | Autism | Brain | Neuropsychology | Child & adolescent psychiatry | Index Medicus | Abridged Index Medicus
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7. Full Text Structural brain abnormalities in adolescents with autism spectrum disorder and patients with attention deficit/hyperactivity disorder
by Brieber, Sarah and Neufang, Susanne and Bruning, Nicole and Kamp‐Becker, Inge and Remschmidt, Helmut and Herpertz‐Dahlmann, Beate and Fink, Gereon R and Konrad, Kerstin
Journal of Child Psychology and Psychiatry, ISSN 0021-9630, 12/2007, Volume 48, Issue 12, pp. 1251 - 1258
Background:  Although autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) are two distinct neurodevelopmental diseases, they... 
VBM | structural MRI | autistic disorder | ADD/ADHD | Structural MRI | Autistic disorder | ADHD | VOLUMES | BDNF | PSYCHIATRY | NEUROTROPHIC FACTOR | PSYCHOLOGY, DEVELOPMENTAL | HIPPOCAMPAL | DEFICIT-HYPERACTIVITY DISORDER | ASPERGER-SYNDROME | PERVASIVE DEVELOPMENTAL DISORDERS | CHILDREN | EXECUTIVE FUNCTION | Brain | Cognitive Processes | Diagnostic Tests | Hyperactivity | Memory | Identification | Control Groups | Patients | Autism | Comparative Analysis | Brain Hemisphere Functions | Attention Deficit Disorders | Pervasive Developmental Disorders | Genetics | Adolescents | Symptoms (Individual Disorders) | Severity of Illness Index | Autistic Disorder - pathology | Humans | Attention Deficit Disorder with Hyperactivity - pathology | Asperger Syndrome - pathology | Parietal Lobe - pathology | Asperger Syndrome - diagnosis | Magnetic Resonance Imaging | Image Processing, Computer-Assisted | Adolescent | Brain - pathology | Brain Mapping | Attention Deficit Disorder with Hyperactivity - diagnosis | Autistic Disorder - diagnosis | Temporal Lobe - pathology | Child | Interpersonal Relations | Frontal Lobe - pathology | Psychological aspects | Care and treatment | Usage | Magnetic resonance imaging | Abnormalities | Youth | Teenagers | Health aspects | Risk factors | Attention deficit disorder | Brain research | Child psychology | Index Medicus
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