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Nature Immunology, ISSN 1529-2908, 2014, Volume 15, Issue 8, pp. 727 - 737
Journal Article
Arthritis & Rheumatology, ISSN 2326-5191, 12/2015, Volume 67, Issue 12, pp. 3234 - 3244
Objective. To determine the relationships between systemic sclerosis (SSc)-related autoantibodies, as well as their clinical associations, in a... 
ANTIBODIES | ANTRAL VASCULAR ECTASIA | SUBSETS | CLASSIFICATION | PREVALENCE | RHEUMATOLOGY | JAPANESE PATIENTS | FRENCH | RNA-POLYMERASE-III | CLINICAL-SIGNIFICANCE | FEATURES | Receptors, Platelet-Derived Growth Factor - immunology | Gastric Antral Vascular Ectasia - immunology | Humans | Middle Aged | Centromere Protein B - immunology | Immunoblotting | Male | Raynaud Disease - etiology | DNA Topoisomerases, Type I - immunology | Esophageal Motility Disorders - etiology | Centromere Protein A | Scleroderma, Systemic - complications | Ribonucleoproteins - immunology | Female | Contracture - immunology | Gastric Antral Vascular Ectasia - etiology | Telangiectasis - immunology | Principal Component Analysis | DNA-Binding Proteins - immunology | Exoribonucleases - immunology | RNA-Binding Proteins - immunology | Scleroderma, Systemic - immunology | RNA Polymerase III - immunology | Scleroderma, Systemic - epidemiology | Chromosomal Proteins, Non-Histone - immunology | Autoantibodies - immunology | Ku Autoantigen | Telangiectasis - etiology | Smoking - epidemiology | Autoantigens - immunology | Sex Factors | Aged | Exosome Multienzyme Ribonuclease Complex - immunology | Pol1 Transcription Initiation Complex Proteins - immunology | Raynaud Disease - immunology | Australia | Esophageal Motility Disorders - immunology | Antigens, Nuclear - immunology | Neoplasms - epidemiology | Cohort Studies | Contracture - etiology | Principal components analysis | RNA polymerase | Autoimmune diseases | Patients | Index Medicus | Abridged Index Medicus
Journal Article
Arthritis & Rheumatology, ISSN 2326-5191, 10/2016, Volume 68, Issue 10, pp. 2492 - 2502
ObjectiveAntinuclear antibodies (ANAs) are detected in approximate to 18% of females, yet autoimmune disease develops in only 5-8%. Immunologic differences... 
SYSTEMIC-LUPUS-ERYTHEMATOSUS | INTERFERON | RISK-FACTORS | CYTOKINE PRODUCTION | DENDRITIC CELLS | ANTINUCLEAR ANTIBODIES | RHEUMATOLOGY | EXPRESSION | BLOOD MONONUCLEAR-CELLS | IG-LIKE RECEPTOR-1 | T-CELLS | Interferon-alpha - pharmacology | Multivariate Analysis | Phosphoproteins - drug effects | Interferon-beta - immunology | Antibodies, Antinuclear - immunology | Humans | Middle Aged | Interleukin-17 - immunology | STAT1 Transcription Factor - drug effects | Centromere Protein B - immunology | Male | Monocytes - immunology | Ribosomal Proteins - immunology | Healthy Volunteers | Case-Control Studies | Leukocytes - immunology | Young Adult | Flow Cytometry | Autoimmunity - immunology | Lupus Erythematosus, Systemic - immunology | Ribonucleoproteins - immunology | Tumor Necrosis Factor-alpha - immunology | Aged, 80 and over | Adult | B-Lymphocyte Subsets - immunology | Female | Interleukin-12 Subunit p40 - immunology | Cytokines - immunology | Interleukin 1 Receptor Antagonist Protein - immunology | Immunophenotyping | Logistic Models | Nuclear Proteins - immunology | STAT1 Transcription Factor - immunology | Stem Cell Factor - immunology | Interferon-alpha - immunology | Autoantibodies - immunology | Interferon-gamma - immunology | STAT3 Transcription Factor - drug effects | Sex Factors | Aged | Granulocyte Colony-Stimulating Factor - immunology | STAT3 Transcription Factor - immunology | Plasma Cells - immunology | Index Medicus | Abridged Index Medicus | Systemic Lupus Erythematosus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2009, Volume 119, Issue 5, pp. 1335 - 1349
Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of oxidized lipoproteins and apoptotic cells. Adaptive immune responses to... 
ATHEROSCLEROTIC LESIONS | MEDICINE, RESEARCH & EXPERIMENTAL | STREPTOCOCCUS-PNEUMONIAE | B-CELL LINEAGES | LIPID-PEROXIDATION PRODUCTS | LINKED-IMMUNOSORBENT-ASSAY | APOPTOTIC CELLS | IN-VIVO | MONOCLONAL AUTOANTIBODIES | LOW-DENSITY-LIPOPROTEIN | OXIDIZED PHOSPHOLIPIDS | Germ-Free Life - immunology | B-Lymphocyte Subsets - transplantation | Antibody Affinity - immunology | Male | Adoptive Transfer | Phosphorylcholine - analogs & derivatives | Immunoglobulin M - immunology | Epitopes - immunology | Phosphorylcholine - immunology | Antibody Specificity - immunology | B-Lymphocyte Subsets - immunology | Female | Fetal Blood - immunology | Receptors, LDL - genetics | Antibody Formation - immunology | Atherosclerosis - pathology | Atherosclerosis - immunology | Oxidation-Reduction | Serum Albumin, Bovine - immunology | Malondialdehyde - analogs & derivatives | Mice, Inbred C57BL | Phagocytosis - immunology | Macrophages, Peritoneal - immunology | Homeodomain Proteins - genetics | Mice, Knockout | Immunity, Innate - immunology | Animals | Apoptosis - immunology | Immunoglobulin M - blood | Malondialdehyde - immunology | Mice | Lipoproteins, LDL - immunology | Proteolipids | Oxidative stress | Care and treatment | Lipoproteins | Hypercholesterolemia | Atherosclerosis | Physiological aspects | Genetic aspects | Research | Blood lipoproteins | Risk factors | Index Medicus | Abridged Index Medicus | Immunoglobulin M | Peritoneal | Antibody Specificity | pathology | Mikrobiologi inom det medicinska området | Macrophages | Immunity | B-Lymphocyte Subsets | Receptors | genetics | LDL | immunology | Bovine | Antibody Affinity | Epitopes | Phosphorylcholine | blood | Malondialdehyde | Inbred C57BL | Knockout | Serum Albumin | Microbiology in the medical area | Homeodomain Proteins | analogs & derivatives | transplantation | Germ-Free Life | Antibody Formation | Innate | Fetal Blood | Phagocytosis | Apoptosis
Journal Article
PLoS Medicine, ISSN 1549-1277, 2006, Volume 3, Issue 7, pp. 1152 - 1164
Background: The autoimmune regulator (AIRE) gene influences thymic self-tolerance induction. In autoimmune polyendocrinopathy syndrome type 1 (APS1; OMIM... 
DIABETES-MELLITUS | MYASTHENIA-GRAVIS PATIENTS | MEDICINE, GENERAL & INTERNAL | INTERFERON-ALPHA | SYNDROME TYPE-I | NEUTRALIZING ANTIBODIES | DENDRITIC CELLS | IFN-GAMMA | DISEASE | EXPRESSION | T-CELLS | Antibody Specificity | Polyendocrinopathies, Autoimmune - diagnosis | Alopecia - immunology | Autoantibodies - blood | Dendritic Cells - immunology | Humans | Middle Aged | Child, Preschool | Male | Interferon Type I - immunology | Interferons - immunology | Lymphocyte Subsets - immunology | Palatine Tonsil - immunology | Autoimmunity - immunology | Polyendocrinopathies, Autoimmune - genetics | Thymoma - immunology | HLA Antigens - immunology | Genotype | Polyendocrinopathies, Autoimmune - immunology | Lymphoid Tissue - pathology | Thymus Gland - ultrastructure | Norway - epidemiology | Adolescent | Cell Line, Tumor | Candidiasis, Chronic Mucocutaneous - etiology | Interferons - physiology | Finland - epidemiology | Self Tolerance - immunology | Transcription Factors - deficiency | Alopecia - etiology | Neutralization Tests | Keratoconjunctivitis - immunology | Keratoconjunctivitis - etiology | Myasthenia Gravis - etiology | Lymphoid Tissue - immunology | Thymus Neoplasms - immunology | Antigen Presentation | Immunoglobulin G - immunology | Self Tolerance - genetics | Interleukins - immunology | Adult | Female | Candidiasis, Chronic Mucocutaneous - immunology | Transcription Factors - genetics | Polyendocrinopathies, Autoimmune - epidemiology | Interferon-alpha - immunology | Thymus Neoplasms - complications | Autoantibodies - immunology | Interferons - classification | Thymus Gland - immunology | Myasthenia Gravis - immunology | Thymoma - complications | Development and progression | Genetic aspects | Research | Autoimmune diseases | Index Medicus | Allergy | Immunology | Gene Therapy | Genomics | Autoimmune Diseases | Genetics | Immunology and Allergy
Journal Article
Arthritis & Rheumatology, ISSN 2326-5191, 11/2016, Volume 68, Issue 11, pp. 2717 - 2727
Journal Article
Journal of Neurology, Neurosurgery & Psychiatry, ISSN 0022-3050, 04/2017, Volume 88, Issue 4, pp. 353 - 361
Journal Article
Journal of Immunology, ISSN 0022-1767, 02/2014, Volume 192, Issue 3, pp. 919 - 928
The Lyn tyrosine kinase regulates inhibitory signaling in B and myeloid cells: loss of Lyn results in a lupus-like autoimmune disease with hyperactive B cells... 
SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACTIVATION | PROTEIN | DENDRITIC CELLS | DISEASE | GERMINAL CENTER | DEFICIENT MICE | IMMUNOLOGY | MATURATION | AUTOANTIBODY PRODUCTION | T-CELLS | T-Lymphocyte Subsets - immunology | Antibody Specificity | Antibodies, Antinuclear - biosynthesis | Myeloproliferative Disorders - enzymology | Immune Complex Diseases - immunology | Spleen - immunology | Kidney - pathology | Antibodies, Antinuclear - immunology | Cell Count | Germinal Center - immunology | Kidney - immunology | Homeostasis | Myeloproliferative Disorders - immunology | Immunoglobulin M - immunology | Myeloproliferative Disorders - genetics | src-Family Kinases - deficiency | Lupus Nephritis - etiology | Immunoglobulin G - biosynthesis | Autoimmunity - immunology | Immunoglobulin G - immunology | Myeloid Differentiation Factor 88 - immunology | Calcium Signaling - immunology | Spleen - pathology | Immunoglobulin Class Switching | Disease Models, Animal | B-Lymphocytes - enzymology | Lymphocyte Activation | Mice, Inbred C57BL | Mice, Transgenic | Lupus Nephritis - immunology | Germinal Center - pathology | Organ Specificity | src-Family Kinases - immunology | Immune Complex Diseases - pathology | Antibodies, Antinuclear - genetics | Lupus Nephritis - enzymology | Animals | B-Lymphocytes - immunology | Myeloid Differentiation Factor 88 - deficiency | Lymphopoiesis - immunology | Mice | src-Family Kinases - genetics | Immunoglobulin M - biosynthesis | Plasma Cells - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Nature, ISSN 0028-0836, 11/2011, Volume 479, Issue 7374, pp. 538 - 541
Journal Article