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PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, pp. e52911 - e52911
Autoantibodies against the second extracellular loop of the β(1)-adrenergic receptor (β(1)-AA) not only contribute to increased susceptibility to heart... 
Autoantibodies - metabolism | Metoprolol - pharmacology | Autoantibodies - blood | Humans | Middle Aged | Adrenergic beta-1 Receptor Antagonists - pharmacology | Male | Interferon-gamma - metabolism | Signal Transduction - immunology | Isoquinolines - pharmacology | T-Lymphocytes - metabolism | T-Lymphocytes - drug effects | Receptors, Adrenergic, beta-1 - immunology | Female | p38 Mitogen-Activated Protein Kinases - metabolism | Phosphorylation - drug effects | Cyclic AMP-Dependent Protein Kinases - metabolism | Adrenergic beta-Agonists - pharmacology | Rats | Receptors, Adrenergic, beta-1 - metabolism | Imidazoles - pharmacology | Sulfonamides - pharmacology | Cardiomyopathy, Dilated - metabolism | Rats, Sprague-Dawley | Animals | Signal Transduction - drug effects | Isoproterenol - pharmacology | Cardiomyopathy, Dilated - immunology | T-Lymphocytes - immunology | Aged | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Health care | Protein kinase A | Heart | Cell proliferation | Flow cytometry | Phosphorylation | Cardiomyopathy | Interleukin | Lymphocytes T | Kinases | Beta blockers | Western blotting | Proteins | Interleukin 4 | Cell growth | Pathways | Lymphocytes | Rodents | Physiology | Heart diseases | Kits | Enzyme-linked immunosorbent assay | Heart failure | Antigens | Metoprolol | Autoantibodies | Cytokines | Internal medicine | Secretion | Cyclic AMP | MAP kinase | CD3 antigen | Gene expression | Patients | Cytometry | Hospitals | Inhibitors | Dilated cardiomyopathy | γ-Interferon | Sampling methods | Interferon | Adrenergic receptors | Diabetes | Cholecystokinin | Laboratory animals | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2013, Volume 288, Issue 23, pp. 16916 - 16925
Journal Article
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN 0363-6119, 08/2012, Volume 303, Issue 4, pp. R353 - R358
Journal Article
American Journal of Hypertension, ISSN 0895-7061, 3/2016, Volume 29, Issue 3, pp. 405 - 412
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 12/2009, Volume 297, Issue 6, pp. G1206 - G1213
Singh J, Mehendiratta V, Del Galdo F, Jimenez SA, Cohen S, DiMarino AJ, Rattan S. Immunoglobulins from scleroderma patients inhibit the muscarinic receptor... 
Muscarinic receptor | Autoantibodies | Rectoanal function | Systemic sclerosis | rectoanal function | PHYSIOLOGY | MYOELECTRIC ACTIVITY | KINASE | SJOGRENS-SYNDROME | GASTROINTESTINAL MANIFESTATIONS | RELAXATION | SYSTEMIC-SCLEROSIS | ESOPHAGEAL DYSFUNCTION | KNOCKOUT MICE | muscarinic receptor | systemic sclerosis | NEURONAL ANTIBODIES | GASTROENTEROLOGY & HEPATOLOGY | autoantibodies | Muscarinic Agonists - pharmacology | Autoantibodies - blood | Humans | Middle Aged | Receptor, Muscarinic M3 - drug effects | Benzofurans - pharmacology | Male | Case-Control Studies | Pyrrolidines - pharmacology | Dose-Response Relationship, Drug | Receptor, Muscarinic M3 - immunology | Bethanechol - pharmacology | Phenylephrine - pharmacology | Piperidines - pharmacology | Muscarinic Antagonists - pharmacology | Potassium Chloride - pharmacology | Scleroderma, Systemic - physiopathology | Anal Canal - physiopathology | Immunoglobulins - blood | Aged, 80 and over | Adult | Female | Anal Canal - drug effects | Myocytes, Smooth Muscle - drug effects | Rats | Scleroderma, Systemic - immunology | Rats, Sprague-Dawley | Anal Canal - immunology | Animals | Muscle Contraction - drug effects | Myocytes, Smooth Muscle - immunology | Adrenergic alpha-Agonists - pharmacology | Aged | In Vitro Techniques | Immunoglobulins | Systemic scleroderma | Scleroderma (Disease) | Physiological aspects | Muscle cells | Research | Muscarinic receptors | Proteins | Multiple sclerosis | Neurotransmitters | Gastrointestinal diseases | Effects | Muscular system | Cells | Index Medicus | Hormones and Signaling
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, pp. e67020 - e67020
Ample evidence has shown that autoantibodies against AT1 receptors (AT1-AA) are closely associated with human cardiovascular disease. The aim of this study was... 
AGONISTIC AUTOANTIBODIES | CELLS | ANGIOTENSIN-II | PREECLAMPSIA | EXPRESSION | MULTIDISCIPLINARY SCIENCES | Aorta - ultrastructure | Rats, Wistar | Humans | Myocardial Contraction - drug effects | Systole - drug effects | Endothelium, Vascular - drug effects | Male | Nitroprusside - pharmacology | Muscle, Smooth, Vascular - physiopathology | Endothelins - blood | Endothelium, Vascular - ultrastructure | Heart Rate - drug effects | Chalcone - pharmacology | Chalcone - analogs & derivatives | Blood Pressure - drug effects | Diastole - drug effects | Aorta - physiopathology | Receptor, Angiotensin, Type 1 - immunology | Quinones - pharmacology | Muscle, Smooth, Vascular - drug effects | NG-Nitroarginine Methyl Ester - pharmacology | Nitric Oxide - blood | Immunization | Muscle, Smooth, Vascular - ultrastructure | Acetylcholine - pharmacology | Aorta - drug effects | Endothelium, Vascular - physiopathology | Rats | Cardiotonic Agents - pharmacology | Indomethacin - pharmacology | Antibodies - pharmacology | Aorta - pathology | Muscle, Smooth, Vascular - pathology | Animals | Endothelium, Vascular - pathology | Vasodilation - drug effects | In Vitro Techniques | Lipoproteins, LDL - blood | Hypertension | Autoimmunity | Viral antibodies | Heart beat | Analysis | Antibodies | Smooth muscle | Medicine, Preventive | Preventive health services | Endothelium | Cell proliferation | Therapy | Peptides | Receptors | Rodents | Aorta | Physiology | Blood pressure | Immunoglobulins | Autoantibodies | Muscles | Inflammation | Thorax | Endothelial cells | Heart rate | Medicine | Nitric oxide | Preeclampsia | Infiltration | Receptor mechanisms | Cardiovascular diseases | Cell migration | Structure-function relationships | Index Medicus
Journal Article
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 10/2013, Volume 133, Issue 10, pp. 2390 - 2399
Journal Article
European Journal of Immunology, ISSN 0014-2980, 07/2017, Volume 47, Issue 7, pp. 1211 - 1219
Disturbances of plasma cell homeostasis and auto‐antibody production are hallmarks of systemic lupus erythematosus. The aim of this study was to explore the... 
Anti‐dsDNA | Plasma cell niche | STAT‐3 | Cytokines | Antibody‐secreting cells | Anti‐ENA | SLE | Anti-ENA | Anti-dsDNA | STAT-3 | Antibody-secreting cells | RHEUMATOID-ARTHRITIS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | BONE-MARROW | IMMUNOLOGY | PLASMA-CELLS | DISEASE-ACTIVITY | B-CELLS | ADHESION MOLECULE EXPRESSION | AUTOANTIBODY PRODUCTION | AUTOIMMUNE-DISEASE | T-CELLS | Antibody-Producing Cells - drug effects | Cell Proliferation | Antibodies, Antinuclear - immunology | Apoptosis - drug effects | Humans | Middle Aged | Male | Tumor Necrosis Factor Ligand Superfamily Member 13 - pharmacology | Lupus Erythematosus, Systemic - blood | DNA - blood | Young Adult | Antibodies, Antinuclear - blood | Lupus Erythematosus, Systemic - immunology | Adult | Female | Cyclic S-Oxides - pharmacology | Interleukins - pharmacology | STAT3 Transcription Factor - metabolism | Pyrazoles - pharmacology | DNA - immunology | Antibody-Producing Cells - immunology | Interleukin-6 - pharmacology | Adolescent | Aged | B-Cell Activating Factor - pharmacology | Chemokine CXCL2 - pharmacology | Viral antibodies | Medicine, Experimental | Antibodies | Medical research | Biological products | Cell proliferation | Cell culture | CXCL12 protein | Markers | Stat3 protein | Homeostasis | Cultures | Activation | Patients | APRIL protein | Interleukin 6 | Chronic conditions | Cell activation | Inhibitors | Systemic lupus erythematosus | Lymphocytes B | BLyS protein | Interleukin 21 | Anti-DNA antibodies | Autoimmune diseases | Apoptosis | Index Medicus
Journal Article
Kidney International, ISSN 0085-2538, 08/2011, Volume 80, Issue 4, pp. 378 - 388
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2010, Volume 107, Issue 29, pp. 13075 - 13080
Activation of the B-cell antigen receptor (BCR) signaling pathway contributes to the initiation and maintenance of B-cell malignancies and autoimmune diseases.... 
T lymphocytes | Animal models | Disease models | Gels | B lymphocytes | B cell lymphoma | Arthritis | Mice | Autoimmune diseases | Tumors | X-linked agammaglobulinemia | Lymphoma | COLLAGEN-INDUCED ARTHRITIS | THERAPY | RITUXIMAB | MULTIDISCIPLINARY SCIENCES | lymphoma | DOGS | FAMILY KINASES | BTK | RECEPTOR | DEPLETION | MICE | Arthritis, Experimental - drug therapy | Pyrazoles - therapeutic use | Humans | Benzofurans - administration & dosage | Benzofurans - pharmacology | Autoantibodies - biosynthesis | Pyrimidines - chemistry | Benzofurans - chemistry | Protein Kinase Inhibitors - chemistry | Pyrazoles - chemistry | Lymphoma, B-Cell - enzymology | Autoimmune Diseases - drug therapy | Disease Models, Animal | Lymphoma, B-Cell - drug therapy | Pyrazoles - pharmacology | B-Lymphocytes - enzymology | Benzofurans - therapeutic use | Autoimmune Diseases - enzymology | Administration, Oral | Pyrimidines - administration & dosage | Treatment Outcome | Pyrimidines - pharmacology | Receptors, Antigen, B-Cell - immunology | B-Lymphocytes - drug effects | Protein Kinase Inhibitors - administration & dosage | Pyrazoles - administration & dosage | Animals | B-Lymphocytes - immunology | Signal Transduction - drug effects | Lymphocyte Activation - drug effects | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Dogs | Protein Kinase Inhibitors - pharmacology | Protein-Tyrosine Kinases - antagonists & inhibitors | Tyrosine | Cell receptors | Models | Lymphomas | Research | Properties | Antigens | Biochemistry | Mutation | Kinases | Cells | Cancer | Index Medicus | Biological Sciences
Journal Article
Journal of Immunology Research, ISSN 2314-8861, 2015, Volume 2015, pp. 369462 - 15