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1. Full Text Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies
by Dalmau, Josep, MD and Gleichman, Amy J, BS and Hughes, Ethan G, BS and Rossi, Jeffrey E, BA and Peng, Xiaoyu, BS and Lai, Meizan, MD and Dessain, Scott K, MD and Rosenfeld, Myrna R, MD and Balice-Gordon, Rita, PhD and Lynch, David R, MD
Lancet Neurology, The, ISSN 1474-4422, 2008, Volume 7, Issue 12, pp. 1091 - 1098
Summary Background A severe form of encephalitis associated with antibodies against NR1–NR2 heteromers of the NMDA receptor was recently identified. We aimed... 
Neurology | IMMUNITY | OVARIAN TERATOMA | AUTOIMMUNITY | DYSKINESIA | DISEASE | DISORDERS | SYNAPTIC PLASTICITY | MIDAZOLAM | VIRUSES | CLINICAL NEUROLOGY | KETAMINE | Neurocognitive Disorders - immunology | Encephalitis - diagnosis | Protein Subunits - immunology | Teratoma - physiopathology | Humans | Middle Aged | Ovarian Neoplasms - physiopathology | Paraneoplastic Syndromes, Nervous System - immunology | Child, Preschool | Male | Epilepsy - physiopathology | Epitopes - immunology | Young Adult | Autoimmune Diseases of the Nervous System - physiopathology | Encephalitis - physiopathology | Epilepsy - immunology | Adult | Female | Child | Receptors, N-Methyl-D-Aspartate - immunology | Autoimmune Diseases of the Nervous System - diagnosis | Cell Line | Paraneoplastic Syndromes, Nervous System - physiopathology | Brain - physiopathology | Cells, Cultured | Neurocognitive Disorders - physiopathology | Rats | Teratoma - immunology | Encephalitis - immunology | Autoimmune Diseases of the Nervous System - immunology | Autoantibodies - immunology | Animals | Autoantigens - immunology | Adolescent | Aged | Brain - immunology | Ovarian Neoplasms - immunology | Viral antibodies | Antibodies | Methyl aspartate | Encephalitis | Neurosciences | Analysis | Index Medicus | Cell culture | Translation | Glutamic acid receptors (ionotropic) | Memory | N-Methyl-D-aspartic acid receptors | Glutamic acid receptors | Epitopes | Hospitals | Hypoventilation | Autonomic nervous system | Immunotherapy | Dendrites | Children | teratoma | Age | Enzyme-linked immunosorbent assay | Dyskinesia | Seizures | Tumors
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2. Full Text N-methyl-d-aspartate antibody encephalitis: Temporal progression of clinical and paraclinical observations in a predominantly non-paraneoplastic disorder of both sexes
by Irani, Sarosh R and Bera, Katarzyna and Waters, Patrick and Zuliani, Luigi and Maxwell, Susan and Zandi, Michael S and Friese, Manuel A and Galea, Ian and Kullmann, Dimitri M and Beeson, David and Lang, Bethan and Bien, Christian G and Vincent, Angela
Brain, ISSN 0006-8950, 06/2010, Volume 133, Issue 6, pp. 1655 - 1667
Antibodies to the N-methyl-d-aspartate subtype of glutamate receptor have been associated with a newly-described encephalopathy that has been mainly identified... 
Autoimmunity | Paraneoplastic | Non-paraneoplastic | Immunotherapy-responsive | N-methyl-d-aspartate receptor-antibody encephalitis | ENCEPHALOMYELITIS | non-paraneoplastic | LIMBIC ENCEPHALITIS | NMDA-RECEPTOR ENCEPHALITIS | immunotherapy-responsive | SCHIZOPHRENIA | NEUROSCIENCES | CLINICAL NEUROLOGY | ENCEPHALOPATHY | WOMEN | OVARIAN TERATOMA | autoimmunity | AQUAPORIN-4 | paraneoplastic | Autoantibodies - metabolism | Encephalitis - diagnosis | Autoantibodies - blood | Humans | Middle Aged | Paraneoplastic Syndromes, Nervous System - immunology | Child, Preschool | Male | Paraneoplastic Syndromes, Nervous System - therapy | Young Adult | Autoimmune Diseases of the Nervous System - physiopathology | Encephalitis - physiopathology | Time Factors | Paraneoplastic Syndromes, Nervous System - diagnosis | Adult | Female | Child | Receptors, N-Methyl-D-Aspartate - immunology | Autoimmune Diseases of the Nervous System - diagnosis | Cell Line | Encephalitis - therapy | Paraneoplastic Syndromes, Nervous System - physiopathology | Brain - physiopathology | Encephalitis - immunology | Disease Progression | Autoantibodies - cerebrospinal fluid | Adolescent | Brain - pathology | Autoimmune Diseases of the Nervous System - therapy | Original
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3. Full Text Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy: A Novel Meningoencephalomyelitis
by Fang, Boyan and McKeon, Andrew and Hinson, Shannon R and Kryzer, Thomas J and Pittock, Sean J and Aksamit, Allen J and Lennon, Vanda A
JAMA Neurology, ISSN 2168-6149, 11/2016, Volume 73, Issue 11, pp. 1297 - 1307
IMPORTANCE: A novel astrocytic autoantibody has been identified as a biomarker of a relapsing autoimmune meningoencephalomyelitis that is immunotherapy... 
ANTIBODIES | CELLS | CANINE NECROTIZING MENINGOENCEPHALITIS | ENCEPHALITIS | AUTOANTIBODY | CEREBROSPINAL-FLUIDS | CLINICAL NEUROLOGY | PUG DOGS | POTASSIUM CHANNEL | ANTIGEN | GFAP | Meningoencephalitis - physiopathology | Recurrence | Meningoencephalitis - cerebrospinal fluid | Autoantibodies - blood | Humans | Immunoglobulin G | Middle Aged | Male | Glial Fibrillary Acidic Protein - immunology | Meningoencephalitis - blood | Young Adult | Autoimmune Diseases of the Nervous System - physiopathology | Astrocytes - immunology | HEK293 Cells | Adult | Female | Retrospective Studies | Paraneoplastic Syndromes, Nervous System - cerebrospinal fluid | Paraneoplastic Syndromes, Nervous System - physiopathology | Myelitis - physiopathology | Myelitis - blood | Biomarkers - blood | Myelitis - cerebrospinal fluid | Autoantibodies - cerebrospinal fluid | Autoimmune Diseases of the Nervous System - cerebrospinal fluid | Paraneoplastic Syndromes, Nervous System - blood | Aged | Biomarkers - cerebrospinal fluid | Autoimmune Diseases of the Nervous System - blood | Index Medicus | Abridged Index Medicus
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4. Full Text Clinical and immunological characteristics of the spectrum of GFAP autoimmunity: A case series of 22 patients
by Iorio, Raffaele and Damato, Valentina and Evoli, Amelia and Gessi, Marco and Gaudino, Simona and Di Lazzaro, Vincenzo and Spagni, Gregorio and Sluijs, Jacqueline A and Hol, Elly M
Journal of Neurology, Neurosurgery and Psychiatry, ISSN 0022-3050, 02/2018, Volume 89, Issue 2, pp. 138 - 146
Objective To report the clinical and immunological characteristics of 22 new patients with glial fibrillar acidic protein (GFAP) autoantibodies. Methods From... 
autoimmune encephalitis | autoimmune neurology | meningoencephalitis | astrocytes | autoantibodies | AUTOANTIBODIES | SURGERY | DENDRITIC CELLS | PSYCHIATRY | ALZHEIMERS-DISEASE | MACROPHAGES | ASTROCYTES | CLINICAL NEUROLOGY | FIBRILLARY ACIDIC PROTEIN | ENCEPHALITIS | CENTRAL-NERVOUS-SYSTEM | CHOROID-PLEXUS | CORTICOSTEROIDS | Meningoencephalitis - physiopathology | Glial Fibrillary Acidic Protein - genetics | Brain - diagnostic imaging | Humans | Middle Aged | Movement Disorders - immunology | Male | Plasma Exchange | Ovarian Neoplasms - complications | Cerebellar Ataxia - immunology | Meningoencephalitis - immunology | Young Adult | Autoimmune Diseases of the Nervous System - physiopathology | Carcinoma - complications | Myelitis - immunology | Immunotherapy | Encephalomyelitis - therapy | Aged, 80 and over | Child | Myoclonus - immunology | Myelitis - physiopathology | Spinal Cord - diagnostic imaging | Autoimmune Diseases of the Nervous System - complications | Mice, Knockout | Myelitis - complications | Magnetic Resonance Imaging | Meningoencephalitis - complications | Cerebellar Ataxia - complications | Cerebellar Ataxia - therapy | Movement Disorders - physiopathology | Drug Resistant Epilepsy - immunology | Immunoglobulins, Intravenous - therapeutic use | Protein Isoforms | Adolescent | Drug Resistant Epilepsy - therapy | Mice | Myoclonus - therapy | Glucocorticoids - therapeutic use | Glial Fibrillary Acidic Protein - immunology | Cerebellar Ataxia - physiopathology | Myoclonus - complications | Encephalomyelitis - complications | Encephalomyelitis - physiopathology | Adult | Female | Optic Neuritis - immunology | Optic Neuritis - complications | Optic Neuritis - therapy | Myoclonus - physiopathology | Movement Disorders - complications | Thymus Neoplasms - complications | Autoimmune Diseases of the Nervous System - immunology | Breast Neoplasms - complications | Autoantibodies - immunology | Drug Resistant Epilepsy - complications | Animals | Movement Disorders - therapy | Optic Neuritis - physiopathology | Encephalomyelitis - immunology | Meningoencephalitis - therapy | Aged | Autoimmune Diseases of the Nervous System - therapy | Myelitis - therapy | Thymoma - complications | Drug Resistant Epilepsy - physiopathology | Immunologic Factors - therapeutic use | Autoimmunity | Usage | Care and treatment | Autoantibodies | Autoimmune diseases | Analysis | Encephalitis | Brain | Antigens | Multiple sclerosis | Immunoglobulins | Spinal cord | Dendritic cells | Disease | Epilepsy | Aquaporins | Cognitive ability | Nervous system | Drug resistance | Patients | Proteins | Immunology | Microscopy | Rheumatoid arthritis | Rodents | Ataxia | Animal cognition
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5. Full Text Innate and Adaptive Autoimmunity Directed to the Central Nervous System
by Bhat, Roopa and Steinman, Lawrence
Neuron, ISSN 0896-6273, 2009, Volume 64, Issue 1, pp. 123 - 132
The immune system has two major components, an innate arm and an adaptive arm. Certain autoimmune diseases of the brain represent examples of disorders where... 
MYELIN BASIC-PROTEIN | MULTIPLE-SCLEROSIS LESIONS | GRAY-MATTER PATHOLOGY | HUMAN BRAIN | WHITE-MATTER | EATON MYASTHENIC SYNDROME | INFLAMMASOMES GUARDIANS | CEREBROSPINAL-FLUID | MOLECULAR-BASIS | NEUROSCIENCES | T-CELLS | Interleukin-1 - metabolism | Brain - physiopathology | Humans | Neuroimmunomodulation - physiology | Immunity, Innate | Brain - physiology | Brain Diseases - physiopathology | Spinal Cord - immunology | Autoimmune Diseases of the Nervous System - immunology | Autoimmune Diseases of the Nervous System - physiopathology | Autoimmunity - physiology | Multiple Sclerosis - physiopathology | Brain Diseases - immunology | Animals | Spinal Cord - physiology | Multiple Sclerosis - immunology | Spinal Cord - physiopathology | Models, Neurological | Brain - immunology | Medical research | Spinal cord | Neurosciences | Disease | Insects | Cytokines | Neurons | Autoimmune diseases | Cancer therapies | Fever | Immune system | Cancer | Antibodies
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6. Full Text Post-infectious autoimmune disorders: Sydenham's chorea, PANDAS and beyond
by Williams, Kyle A and Swedo, Susan E
Brain Research, ISSN 0006-8993, 08/2015, Volume 1617, pp. 144 - 154
Abstract Infections, and the resulting immune response to these infections, have recently received increased recognition as pathogenic mechanisms for... 
Obsessive compulsive disorder | Group A Streptococcus | PANDAS | Sydenhamchorea | BRAIN SPECT | BASAL GANGLIA | NEUROSCIENCES | TOURETTE-SYNDROME | STREPTOCOCCAL INFECTIONS | NEUROPSYCHIATRIC DISORDERS | INTRAVENOUS IMMUNOGLOBULIN | OBSESSIVE-COMPULSIVE SYMPTOMS | THERAPEUTIC PLASMA-EXCHANGE | STRIATAL HYPERMETABOLISM | RHEUMATIC-FEVER | Autoimmune Diseases - physiopathology | Chorea - physiopathology | Chorea - drug therapy | Brain - physiopathology | Humans | Middle Aged | Male | Autoimmune Diseases of the Nervous System - drug therapy | Autoimmune Diseases of the Nervous System - pathology | Chorea - pathology | Young Adult | Autoimmune Diseases of the Nervous System - physiopathology | Adolescent | Brain - pathology | Streptococcal Infections - physiopathology | Adult | Female | Streptococcal Infections - drug therapy | Streptococcal Infections - pathology | Aged | Autoimmune Diseases - pathology | Child | Autoimmune Diseases - drug therapy | Medical colleges | Nervous system diseases | Health aspects | Analysis | Chorea
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7. Full Text The spectrum of autoimmune autonomic neuropathies
by Klein, Caroline M and Vernino, Steven and Lennon, Vanda A and Sandroni, Paola and Fealey, Robert D and Benrud-Larson, Lisa and Sletten, David and Low, Phillip A
Annals of Neurology, ISSN 0364-5134, 06/2003, Volume 53, Issue 6, pp. 752 - 758
We analyzed the clinical characteristics of 18 patients (13 female, 5 male) who had autoimmune autonomic neuropathy (AAN) and ganglionic acetylcholine receptor... 
PANDYSAUTONOMIA | SUDOMOTOR | FAILURE | NEUROSCIENCES | INTRAVENOUS IMMUNOGLOBULIN | CLINICAL NEUROLOGY | Autoantibodies - metabolism | Pupil Disorders - diagnosis | Gastrointestinal Diseases - physiopathology | Gastrointestinal Diseases - epidemiology | Humans | Middle Aged | Autonomic Nervous System Diseases - classification | Male | Gastrointestinal Diseases - diagnosis | Urinary Bladder, Neurogenic - physiopathology | Autoimmune Diseases of the Nervous System - physiopathology | Urinary Bladder, Neurogenic - diagnosis | Pupil Disorders - epidemiology | Sjogren's Syndrome - epidemiology | Aged, 80 and over | Heart Rate - physiology | Adult | Female | Blood Pressure - physiology | Binding Sites | Child | Ganglia, Autonomic - immunology | Autonomic Nervous System Diseases - immunology | Hypohidrosis - physiopathology | Urinary Bladder, Neurogenic - epidemiology | Hypohidrosis - diagnosis | Body Temperature Regulation - physiology | Receptors, Cholinergic - metabolism | Pupil Disorders - physiopathology | Hypohidrosis - epidemiology | Valsalva Maneuver | Autoimmune Diseases of the Nervous System - immunology | Autoantibodies - immunology | Autonomic Nervous System Diseases - physiopathology | Sjogren's Syndrome - diagnosis | Adolescent | Ganglia, Autonomic - metabolism | Receptors, Cholinergic - immunology | Aged
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8. Full Text Autoimmunity Initiates in Nonhematopoietic Cells and Progresses via Lymphocytes in an Interferon-Dependent Autoimmune Disease
by Gall, Alevtina and Treuting, Piper and Elkon, Keith B and Loo, Yueh-Ming and Gale, Michael and Barber, Glen N and Stetson, Daniel B
Immunity, ISSN 1074-7613, 01/2012, Volume 36, Issue 1, pp. 120 - 131
The type I interferon (IFN) response initiated by detection of nucleic acids is important for antiviral defense but is also associated with specific autoimmune... 
B-CELLS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | GENE | I INTERFERONS | CLONAL EXPANSION | CYTOSOLIC DNA | ALPHA | MUTATIONS | IMMUNOLOGY | EXONUCLEASE TREX1 | T-CELLS | Autoimmune Diseases - physiopathology | Autoimmune Diseases - enzymology | Signal Transduction | Phosphoproteins - genetics | Phosphoproteins - metabolism | Mice, Knockout | Autoimmune Diseases of the Nervous System - physiopathology | Animals | Lymphocytes - immunology | Autoimmunity - immunology | Models, Biological | Exodeoxyribonucleases - metabolism | Nervous System Malformations - physiopathology | Interferons - physiology | Mice | Exodeoxyribonucleases - genetics | Autoimmunity | Medical colleges | Autoantibodies | Lymphocytes | Genes | Autoantigens | Interferon | Nucleic acids | Biological response modifiers | Lupus | Autoimmune diseases | Mortality | Viral infections | Immune system
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9. Full Text Advances in the understanding of the mechanism of action of IVIg
by Hartung, Hans-Peter
Journal of Neurology, ISSN 0340-5354, 7/2008, Volume 255, Issue S3, pp. 3 - 6
The IgG molecule is the main component of IVIg. Commercial preparations of IVIg are derived from a pool of donors and subsequently, IVIg products contain... 
Neurology | Neurosciences | immune | Medicine & Public Health | neuropathies | IVIg | antibodies | mechanism | Neuroradiology | Antibodies | Neuropathies | Immune | Mechanism | ANTIINFLAMMATORY ACTIVITY | DERMATOMYOSITIS | CLINICAL NEUROLOGY | GLOBULIN | AUTOIMMUNE | DISEASES | THERAPY | MULTIPLE-SCLEROSIS | INTRAVENOUS IMMUNOGLOBULIN | IMMUNOPATHOGENESIS | Neuromuscular Diseases - immunology | Humans | Peripheral Nervous System Diseases - physiopathology | Autoimmune Diseases of the Nervous System - drug therapy | Immunoglobulins, Intravenous - pharmacology | Neuromuscular Diseases - drug therapy | Neuromuscular Diseases - physiopathology | Autoimmune Diseases of the Nervous System - immunology | Autoimmune Diseases of the Nervous System - physiopathology | B-Lymphocytes - drug effects | B-Lymphocytes - immunology | Autoimmunity - immunology | Immune Tolerance - immunology | T-Lymphocytes - drug effects | T-Lymphocytes - immunology | Cytokines - antagonists & inhibitors | Immunoglobulins, Intravenous - immunology | Peripheral Nervous System Diseases - immunology | Autoimmunity - drug effects | Peripheral Nervous System Diseases - drug therapy | Cytokines - immunology | Immune Tolerance - drug effects | Neuromuscular diseases | Care and treatment | Immune response | Regulation | Research | Peripheral nerve diseases | Health aspects
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10. Full Text Seronegative autoimmune autonomic neuropathy: a distinct clinical entity
by Golden, Elisabeth P and Bryarly, Meredith A and Vernino, Steven
Clinical Autonomic Research, ISSN 0959-9851, 2/2018, Volume 28, Issue 1, pp. 115 - 123
Autoimmune autonomic ganglionopathy (AAG) is associated with ganglionic acetylcholine receptor (gAChR) antibodies. We describe a similar but distinct series of... 
Neurology | Medicine & Public Health | Immunotherapy | Gastroenterology | Autoimmune autonomic ganglionopathy | Diabetes | Ophthalmology | Cardiology | Autonomic neuropathy | Endocrinology | Orthostatic hypotension | Autonomic testing | GANGLIONOPATHY | SENSORY NEUROPATHY | FAILURE | NEUROSCIENCES | CLINICAL NEUROLOGY | THERAPY | RECEPTOR ANTIBODY | ACUTE PANDYSAUTONOMIA | Autoantibodies - blood | Humans | Male | Autoimmune Diseases of the Nervous System - immunology | Autoimmune Diseases of the Nervous System - physiopathology | Autonomic Nervous System Diseases - physiopathology | Autoantigens - immunology | Adult | Female | Receptors, Cholinergic - immunology | Aged | Retrospective Studies | Autoimmune Diseases of the Nervous System - blood | Autonomic Nervous System Diseases - immunology | Viral antibodies | Antibodies | Pain | Intravenous administration | Autonomic nervous system | Rituximab | Acetylcholine | Blood pressure | Neuropathy | Hypotension | Steroid hormones
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11. Full Text Comparisons in fluctuation of muscle strength and function in patients with immune‐mediated neuropathy treated with intravenous versus subcutaneous immunoglobulin
by Christiansen, Ingelise and Markvardsen, Lars H and Jakobsen, Johannes
Muscle & Nerve, ISSN 0148-639X, 04/2018, Volume 57, Issue 4, pp. 610 - 614
IntroductionVariations in muscle strength and function have not been studied in patients with chronic inflammatory demyelinating polyneuropathy and multifocal... 
chronic inflammatory demyelinating polyneuropathy | multifocal motor neuropathy | intravenous immunoglobulin | subcutaneous immunoglobulin | 1ST REVISION | CHARCOT-MARIE-TOOTH | PERIPHERAL-NERVE SOCIETY | INFLAMMATORY DEMYELINATING POLYRADICULONEUROPATHY | NEUROSCIENCES | CLINICAL NEUROLOGY | NEUROLOGICAL SOCIETIES | THERAPY | JOINT TASK-FORCE | QUALITY-OF-LIFE | EUROPEAN FEDERATION | Prospective Studies | Immunoglobulin G - blood | Humans | Middle Aged | Immunologic Factors - administration & dosage | Immunoglobulin G - therapeutic use | Peripheral Nervous System Diseases - therapy | Male | Peripheral Nervous System Diseases - physiopathology | Polyradiculoneuropathy, Chronic Inflammatory Demyelinating - physiopathology | Immunoglobulin G - administration & dosage | Autoimmune Diseases of the Nervous System - physiopathology | Immunoglobulins, Intravenous - therapeutic use | Polyradiculoneuropathy, Chronic Inflammatory Demyelinating - therapy | Injections, Subcutaneous | Aged, 80 and over | Adult | Female | Aged | Autoimmune Diseases of the Nervous System - therapy | Walk Test | Muscle Strength | Hand Strength | Immunologic Factors - therapeutic use | Medicine, Experimental | Medical research | Immunoglobulins | Analysis | Intravenous administration | Muscles | Variations | Inflammation | Neuropathy | Polyneuropathy | Patients | Demyelination | Grip strength | Muscular strength | Variation
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12. Full Text Brain Inflammation in Epilepsy: Experimental and Clinical Evidence
by Vezzani, Annamaria and Granata, Tiziana
Epilepsia, ISSN 0013-9580, 11/2005, Volume 46, Issue 11, pp. 1724 - 1743
Inflammatory reactions occur in the brain in various CNS diseases, including autoimmune, neurodegenerative, and epileptic disorders. Proinflammatory and... 
Neurodegeneration | Innate and adaptive immunity | Anticonvulsant | Autoimmune diseases | Stress | Blood–brain barrier | Seizures | Blood-brain barrier | autoimmune diseases | blood-brain barrier | stress | CELLS | CYTOKINES | anticonvulsant | BARRIER | neurodegeneration | STATUS EPILEPTICUS | innate and adaptive immunity | CNS | KAINIC ACID | CLINICAL NEUROLOGY | MESSENGER-RNA | seizures | CENTRAL-NERVOUS-SYSTEM | RAT HIPPOCAMPUS | TNF-ALPHA | Humans | Blood-Brain Barrier - physiopathology | Cell Death - immunology | Nerve Degeneration - physiopathology | Capillary Permeability - immunology | Epilepsy - physiopathology | Anticonvulsants - pharmacology | Autoimmune Diseases of the Nervous System - physiopathology | Seizures - physiopathology | Encephalitis - physiopathology | Epilepsy - immunology | Anti-Inflammatory Agents - therapeutic use | Inflammation Mediators - physiology | Cell Survival - physiology | Endothelial Cells - physiology | Disease Models, Animal | Inflammation Mediators - immunology | Blood-Brain Barrier - immunology | Anti-Inflammatory Agents - pharmacology | Anticonvulsants - therapeutic use | Encephalitis - immunology | Nerve Degeneration - immunology | Cell Survival - immunology | Endothelial Cells - immunology | Autoimmune Diseases of the Nervous System - immunology | Animals | Seizures - immunology
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