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1. Full Text Droxidopa for neurogenic orthostatic hypotension: A randomized, placebo-controlled, phase 3 trial
by Kaufmann, Horacio and Freeman, Roy and Biaggioni, Italo and Low, Phillip and Pedder, Simon and Hewitt, L Arthur and Mauney, Joe and Feirtag, Michael and Mathias, Christopher J and NOH301 Investigators and On behalf of the NOH301 Investigators
Neurology, ISSN 0028-3878, 07/2014, Volume 83, Issue 4, pp. 328 - 335
OBJECTIVE:To determine whether droxidopa, an oral norepinephrine precursor, improves symptomatic neurogenic orthostatic hypotension (nOH). METHODS:Patients... 
PRESSURE | MULTICENTER | PRECURSOR THERAPY | MANAGEMENT | L-THREO-DOPS | DOUBLE-BLIND | PURE AUTONOMIC FAILURE | CEREBRAL-BLOOD-FLOW | HYPERTENSION | MIDODRINE | CLINICAL NEUROLOGY | Humans | Middle Aged | Male | Multiple System Atrophy - complications | Parkinson Disease - drug therapy | Droxidopa - therapeutic use | Posture | Droxidopa - administration & dosage | Time Factors | Female | Pure Autonomic Failure - complications | Blood Pressure - drug effects | Hypotension, Orthostatic - etiology | Parkinson Disease - complications | Autonomic Nervous System Diseases - complications | Double-Blind Method | Hypotension, Orthostatic - drug therapy | Nervous System Diseases - drug therapy | Treatment Outcome | Autonomic Agents - therapeutic use | Autonomic Agents - adverse effects | Nervous System Diseases - complications | Autonomic Agents - administration & dosage | Droxidopa - adverse effects | Dizziness - drug therapy | Autonomic Nervous System Diseases - drug therapy | Multiple System Atrophy - drug therapy | Aged | Pure Autonomic Failure - drug therapy | 172 | 105
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2. Full Text The Movement Disorder Society Evidence‐Based Medicine Review Update: Treatments for the non‐motor symptoms of Parkinson's disease
by Seppi, Klaus and Weintraub, Daniel and Coelho, Miguel and Perez‐Lloret, Santiago and Fox, Susan H and Katzenschlager, Regina and Hametner, Eva‐Maria and Poewe, Werner and Rascol, Olivier and Goetz, Christopher G and Sampaio, Cristina
Movement Disorders, ISSN 0885-3185, 10/2011, Volume 26, Issue S3, pp. S42 - S80
The Movement Disorder Society (MDS) Task Force on Evidence‐Based Medicine (EBM) Review of Treatments for Parkinson's Disease (PD) was first published in 2002... 
evidence‐based medicine | Parkinson's disease | omega‐3 fatty‐acids | selective serotonin reuptake inhibitors (SSRIs) | transcranial magnetic stimulation | dopamine agonists | tricyclic antidepressants | Transcranial magnetic stimulation | Tricyclic antidepressants | Dopamine agonists | Omega-3 fatty-acids | Selective serotonin reuptake inhibitors (SSRIs) | Evidence-based medicine | DRUG-INDUCED PSYCHOSIS | DOPAMINERGIC-INDUCED HALLUCINATIONS | SCALE MDS-UPDRS | RANDOMIZED CONTROLLED-TRIAL | BOTULINUM-TOXIN-A | QUALITY STANDARDS SUBCOMMITTEE | ACADEMY-OF-NEUROLOGY | omega-3 fatty-acids | CLINICAL NEUROLOGY | DOUBLE-BLIND | PLACEBO-CONTROLLED TRIAL | evidence-based medicine | Parkinson Disease - therapy | Mood Disorders - drug therapy | Autonomic Nervous System Diseases - etiology | Sleep Disorders, Intrinsic - etiology | Humans | Sleep Disorders, Intrinsic - drug therapy | Treatment Outcome | Parkinson Disease - drug therapy | Cognition Disorders - drug therapy | Evidence-Based Medicine | Parkinson Disease - psychology | Psychotropic Drugs - therapeutic use | Randomized Controlled Trials as Topic | Antiparkinson Agents - therapeutic use | Mood Disorders - etiology | Mental Disorders - drug therapy | Autonomic Nervous System Diseases - drug therapy | Cognition Disorders - etiology | Mental Disorders - etiology
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3. Full Text Autonomic nervous system dysfunction in psychiatric disorders and the impact of psychotropic medications: a systematic review and meta-analysis
by Alvares, Gail A., PhD and Quintana, Daniel S., PhD and Hickie, Ian B., MBBS, FRANZCP and Guastella, Adam J., PhD
Journal of Psychiatry and Neuroscience, ISSN 1180-4882, 2016, Volume 41, Issue 2, pp. 89 - 104
Background Autonomic nervous system (ANS) dysfunction is a putative underlying mechanism for increased cardiovascular disease risk in individuals with... 
Psychiatry | Medical Education | POSTTRAUMATIC-STRESS-DISORDER | CARDIAC VAGAL CONTROL | GENERALIZED ANXIETY DISORDER | ALCOHOL-WITHDRAWAL SYNDROME | SERIOUS MENTAL-ILLNESS | PSYCHIATRY | HEART-RATE-VARIABILITY | BLOOD-PRESSURE VARIABILITY | MAJOR DEPRESSIVE DISORDER | POWER-SPECTRAL-ANALYSIS | NEUROSCIENCES | INCREASED QT VARIABILITY | Psychotropic Drugs - adverse effects | Autonomic Nervous System Diseases - complications | Autonomic Nervous System Diseases - physiopathology | Mental Disorders - drug therapy | Autonomic Nervous System Diseases - drug therapy | Humans | Mental Disorders - complications | Mental Disorders - physiopathology | Psychotropic Drugs - therapeutic use | Psychotropic drugs | Psychoses | Drug interactions | Physiological aspects | Dosage and administration | Drug therapy | Observations | Health aspects | Nervous system, Autonomic | Studies | Nervous system | Risk | Research Paper
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4. Full Text Practice parameter: Treatment of nonmotor symptoms of Parkinson disease: Report of the quality standards subcommittee of the American academy of neurology
by Zesiewicz, T.A and Sullivan, K.L and Arnulf, I and Chaudhuri, K.R and Morgan, J.C and Gronseth, G.S and Miyasaki, J and Iverson, D.J and Weiner, W.J and Amer Acad Neurology and Quality Standards Subcommittee of the American Academy of Neurology
Neurology, ISSN 0028-3878, 03/2010, Volume 74, Issue 11, pp. 924 - 931
Objective: Nonmotor symptoms (sleep dysfunction, sensory symptoms, autonomic dysfunction, mood disorders, and cognitive abnormalities) in Parkinson disease... 
CONSTIPATION | DEPRESSION | DAYTIME SLEEPINESS | STIMULATION | MELATONIN | DOUBLE-BLIND | BOTULINUM NEUROTOXIN | ARCHITECTURE | DYSFUNCTION | MODAFINIL | CLINICAL NEUROLOGY | Parkinson Disease - complications | Autonomic Nervous System Diseases - etiology | Sleep Wake Disorders - drug therapy | United States | Autonomic Nervous System Diseases - drug therapy | Humans | Clinical Trials as Topic | Parkinson Disease - drug therapy | Practice Patterns, Physicians | Evidence-Based Medicine | Sleep Wake Disorders - etiology
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5. Full Text Non-motor symptoms in Parkinson's disease
by Park, Ariane and Stacy, Mark
Journal of Neurology, ISSN 0340-5354, 08/2009, Volume 256, Issue 3, pp. S293 - S296
Parkinson's disease is a hypokinetic movement disorder with cardinal motor features of bradykinesia, resting tremor and rigidity. However, non-motor symptoms,... 
DAYTIME SLEEPINESS | Parkinson's disease | Non-motor symptoms | COGNITIVE IMPAIRMENT | LEWY BODY DISEASE | OPEN-LABEL | CLINICAL NEUROLOGY | SLEEP BEHAVIOR DISORDER | MULTIPLE SYSTEM ATROPHY | NEUROGENIC ORTHOSTATIC HYPOTENSION | INDUCED PSYCHOSIS | OVERACTIVE BLADDER | DOUBLE-BLIND | Dopaminergic treatment | Neurocognitive Disorders - etiology | Parkinson Disease - complications | Autonomic Nervous System Diseases - etiology | Cognition Disorders - physiopathology | Sensation Disorders - physiopathology | Antiparkinson Agents - pharmacology | Sleep Wake Disorders - drug therapy | Brain - physiopathology | Humans | Neurocognitive Disorders - physiopathology | Sensation Disorders - etiology | Parkinson Disease - drug therapy | Cognition Disorders - drug therapy | Parkinson Disease - physiopathology | Brain - drug effects | Brain - metabolism | Sensation Disorders - drug therapy | Neurocognitive Disorders - drug therapy | Autonomic Nervous System Diseases - physiopathology | Autonomic Nervous System Diseases - drug therapy | Cognition Disorders - etiology | Sleep Wake Disorders - physiopathology | Sleep Wake Disorders - etiology | Dopamine - metabolism | Complications and side effects | Care and treatment | Dopamine | Health aspects | Movement disorders | Risk factors
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6. Full Text Long-term cardiovascular autonomic and clinical changes after immunoglobulin G immunoadsorption therapy in autoimmune autonomic ganglionopathy
by Barbic, Franca and Dipaola, Franca and Andreetta, Francesca and Brunetta, Enrico and Dalla Vecchia, Laura and Mantegazza, Renato and Furlan, Raffaello and Antozzi, Carlo
Journal of Hypertension, ISSN 0263-6352, 03/2017, Volume 35, Issue 7, pp. 1513 - 1520
A 63-year-old male was diagnosed with autoimmune autonomic ganglionopathy based on the finding of plasma antibodies to the nicotinic acetylcholine receptor... 
autoimmune autonomic ganglionopathy | orthostatic hypotension | spectral analysis | autonomic nervous system | immunoadsorption | Autoimmune Diseases - physiopathology | Heart Rate - immunology | Autonomic Nervous System - drug effects | Autoantibodies - blood | Humans | Middle Aged | Autoimmune Diseases - immunology | Immunoglobulin G - therapeutic use | Male | Treatment Outcome | Ganglia, Autonomic - physiopathology | Autonomic Nervous System - physiopathology | Heart Rate - drug effects | Receptors, Nicotinic - immunology | Norepinephrine - blood | Autonomic Nervous System Diseases - physiopathology | Ganglia, Autonomic - drug effects | Autonomic Nervous System Diseases - drug therapy | Autonomic Nervous System - immunology | Immunoglobulin G - pharmacology | Ganglia, Autonomic - immunology | Autoimmune Diseases - drug therapy | Autonomic Nervous System Diseases - immunology
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7. Full Text Vitamin D in the spectrum of prediabetes and cardiovascular autonomic dysfunction
by Dimova, Rumyana and Tankova, Tsvetalina and Chakarova, Nevena
Journal of Nutrition, ISSN 0022-3166, 09/2017, Volume 147, Issue 9, pp. 1607 - 1615
Vitamin D is a fat-soluble secosteroid hormone with pleiotropic effects. 1,25-Dihydroxyvitamin D coordinates the biosynthesis of neurotransmitters in the... 
Cardiovascular disease | Diabetes | Vitamin D | Prediabetes | Cardiovascular autonomic dysfunction | cardiovascular autonomic dysfunction | cardiovascular disease | RISK-FACTORS | SERUM 25-HYDROXYVITAMIN D | vitamin D | prediabetes | D SUPPLEMENTATION | D DEFICIENCY | IMPAIRED GLUCOSE-TOLERANCE | DIABETIC-NEUROPATHY | NERVE GROWTH-FACTOR | NUTRITION & DIETETICS | INSULIN-RESISTANCE | 1,25-DIHYDROXYVITAMIN D-3 | PLACEBO-CONTROLLED TRIAL | diabetes | Vitamin D Deficiency - complications | Cardiovascular Diseases - prevention & control | Humans | Vitamin D Deficiency - drug therapy | Peripheral Nervous System Diseases - physiopathology | Peripheral Nerves - drug effects | Prediabetic State - drug therapy | Glucose Intolerance - drug therapy | Glucose Intolerance - prevention & control | Glucose Intolerance - etiology | Diabetes Mellitus, Type 2 - etiology | Vitamins - physiology | Prediabetic State - etiology | Peripheral Nervous System Diseases - etiology | Cardiovascular Diseases - etiology | Cardiovascular Diseases - physiopathology | Autonomic Nervous System - drug effects | Autonomic Nervous System - physiology | Diabetes Mellitus, Type 2 - prevention & control | Vitamins - therapeutic use | Peripheral Nerves - physiopathology | Diabetes Mellitus, Type 2 - physiopathology | Prediabetic State - physiopathology | Vitamin D - physiology | Vitamin D - therapeutic use | Dietary Supplements | Peripheral Nervous System Diseases - drug therapy | Physiological aspects | Diabetics | Calcifediol | Alfacalcidol | Prediabetic state
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8. Full Text Botulinum toxin therapy: its use for neurological disorders of the autonomic nervous system
by Dressler, Dirk
Journal of Neurology, ISSN 0340-5354, 3/2013, Volume 260, Issue 3, pp. 701 - 713
Botulinum toxin (BoNT) has gained widespread use for the treatment of overactive muscles, overactive exocrine glands and, most recently, non-muscular pain... 
Neurology | Neurosciences | Medicine & Public Health | Autonomic disorders | Botulinum toxin | Neuroradiology | Therapeutic use | CROCODILE TEARS | PALMAR HYPERHIDROSIS | DETRUSOR-SPHINCTER DYSSYNERGIA | CLINICAL NEUROLOGY | GUIDED INTRAGLANDULAR INJECTIONS | TO-DATE REPORT | A TOXIN | DOUBLE-BLIND | AXILLARY HYPERHIDROSIS | PAINFUL BLADDER SYNDROME | QUALITY-OF-LIFE | Neural Pathways - drug effects | Humans | Nervous System Diseases - drug therapy | Male | Neural Pathways - physiology | Prostatic Diseases - physiopathology | Botulinum Toxins - therapeutic use | Neural Pathways - anatomy & histology | Animals | Autonomic Nervous System Diseases - physiopathology | Autonomic Nervous System Diseases - drug therapy | Prostatic Diseases - pathology | Female | Urinary Bladder Diseases - pathology | Nervous System Diseases - physiopathology | Prostatic Diseases - drug therapy | Autonomic Nervous System Diseases - pathology | Urinary Bladder Diseases - drug therapy | Urinary Bladder Diseases - physiopathology | Nervous System Diseases - pathology | Complications and side effects | Neuromuscular diseases | Dosage and administration | Research | Drug therapy | Achalasia
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9. Full Text Ginkgo biloba L. extract protects against chronic cerebral hypoperfusion by modulating neuroinflammation and the cholinergic system
by Kim, Min-Soo and Bang, Ji Hye and Lee, Jun and Han, Jung-Soo and Baik, Tae Gon and Jeon, Won Kyung
Phytomedicine, ISSN 0944-7113, 11/2016, Volume 23, Issue 12, pp. 1356 - 1364
extract (GBE)—a widely used nutraceutical—is reported to have diverse functions, including positive effects on memory and vasodilatory properties. Although... 
Ginkgo biloba | Neuroinflammation | Chronic cerebral hypoperfusion | Choline acetyltransferase | Toll-like receptor | EGB | CHEMISTRY, MEDICINAL | MICROGLIAL ACTIVATION | ISCHEMIA | MAPK | RAT MODEL | DAMAGE | NEUROPROTECTION | PLANT SCIENCES | VASCULAR COGNITIVE IMPAIRMENT | INTEGRATIVE & COMPLEMENTARY MEDICINE | ATTENUATES WHITE-MATTER | PHARMACOLOGY & PHARMACY | LONG-TERM TREATMENT | Neuroprotective Agents - therapeutic use | Cerebrovascular Disorders - physiopathology | Cerebrovascular Disorders - drug therapy | Cytokines - metabolism | Rats, Wistar | Carotid Stenosis - drug therapy | Rats | Carotid Stenosis - physiopathology | Male | Nerve Tissue Proteins - genetics | Animals | Autonomic Nervous System Diseases - physiopathology | Inflammation - drug therapy | Autonomic Nervous System Diseases - drug therapy | Parasympathetic Nervous System - drug effects | Carotid Artery, Common | Nerve Tissue Proteins - biosynthesis | Cell Proliferation - drug effects | Neurons - drug effects | Plant Extracts - therapeutic use | Inflammation - physiopathology | Shock | Cholinergic mechanisms | Usage | Care and treatment | Ginkgo | Development and progression | Health aspects | Materia medica, Vegetable | Plant extracts
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10. Full Text Baroreflex: A new therapeutic target in human stroke?
by Sykora, Marek and Diedler, Jennifer and Turcani, Peter and Hacke, Werner and Steiner, Thorsten
Stroke, ISSN 0039-2499, 12/2009, Volume 40, Issue 12, pp. e678 - e682
Background and Purpose-Autonomic dysfunction, including increased sympathetic drive and blunted baroreflex, has repeatedly been observed in acute stroke. Of... 
Baroreflex sensitivity | Therapy | Heart-brain relations | Acute stroke | Outcome | baroreflex sensitivity | BEAT BLOOD-PRESSURE | heart-brain relations | ARTERIAL BAROREFLEX | therapy | CLINICAL NEUROLOGY | acute stroke | TRAUMATIC BRAIN-INJURY | HEART-RATE-VARIABILITY | CARDIAC BARORECEPTOR SENSITIVITY | ACUTE ISCHEMIC-STROKE | INSULAR CORTEX | INTRACEREBRAL HEMORRHAGE | PERIPHERAL VASCULAR DISEASE | outcome | BETA-BLOCKER EXPOSURE | DYNAMIC CEREBRAL AUTOREGULATION | Brain Ischemia - complications | Autonomic Nervous System - anatomy & histology | Autonomic Nervous System Diseases - etiology | Cerebral Hemorrhage - drug therapy | Cerebrovascular Circulation - physiology | Humans | Reflex, Abnormal - physiology | Stroke - complications | Cerebral Arteries - physiopathology | Brain Ischemia - physiopathology | Stroke - drug therapy | Cerebral Hemorrhage - physiopathology | Autonomic Nervous System - physiopathology | Stroke - physiopathology | Cerebral Cortex - physiopathology | Baroreflex - drug effects | Autonomic Nervous System Diseases - physiopathology | Autonomic Nervous System Diseases - drug therapy | Brain Ischemia - drug therapy | Cerebral Arteries - innervation | Baroreflex - physiology | Reflex, Abnormal - drug effects | Cerebral Hemorrhage - complications
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11. Peripheral nervous system involvement in systemic lupus erythematosus: a review of the evidence
by Bortoluzzi, Alessandra and Bortoluzzi, Alessandra and Silvagni, Ettore and Silvagni, Ettore and Furini, Federica and Furini, Federica and Piga, Matteo and Piga, Matteo and Govoni, Marcello and Govoni, Marcello
Clinical and experimental rheumatology, ISSN 0392-856X, 01/2019, Volume 37, Issue 1, pp. 146 - 155
In the past years the peripheral nervous system (PNS) involvement in systemic lupus erythematosus (SLE) has received little attention despite its potential... 
Peripheral nervous system | Small fibre neuropathy | Myasthenia gravis | Cranial neuropathy | Polyneuropathy | Neuropsychiatric lupus erythematosus | cranial neuropathy | RHEUMATOID-ARTHRITIS | AUTONOMIC DYSFUNCTION | NEUROLOGICAL MANIFESTATIONS | IMMUNOLOGICAL CHARACTERISTICS | polyneuropathy | GUILLAIN-BARRE-SYNDROME | myasthenia gravis | SMALL FIBER NEUROPATHY | INFLAMMATORY DEMYELINATING POLYNEUROPATHY | peripheral nervous system | RHEUMATOLOGY | neuropsychiatric lupus erythematosus | NEUROPSYCHIATRIC EVENTS | small fibre neuropathy | INTRAVENOUS CYCLOPHOSPHAMIDE | JOINT TASK-FORCE | Lupus Erythematosus, Systemic - complications | Humans | Lupus Erythematosus, Systemic - drug therapy | Lupus Erythematosus, Systemic - immunology | Peripheral Nervous System - physiopathology | Peripheral Nervous System Diseases - complications | Peripheral Nervous System Diseases - immunology | Peripheral Nervous System Diseases - drug therapy
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12. Full Text Chronic activation of endogenous angiotensin‐converting enzyme 2 protects diabetic rats from cardiovascular autonomic dysfunction
by Murça, Tatiane M and Almeida, Tatiane C. S and Raizada, Mohan K and Ferreira, Anderson J
Experimental Physiology, ISSN 0958-0670, 06/2012, Volume 97, Issue 6, pp. 699 - 709
In this study, we evaluated whether the activation of endogenous angiotensin‐converting enzyme 2 (ACE2) would improve the cardiovascular autonomic dysfunction... 
VAGUS NERVE | RENIN-ANGIOTENSIN | PHYSIOLOGY | NEUROPATHY | HEART-RATE CONTROL | REPERFUSION ARRHYTHMIAS | AMBIGUUS NA | SYMPATHETIC OUTFLOW | NUCLEUS-TRACTUS-SOLITARII | MYOCARDIAL DYSFUNCTION | BAROREFLEX CONTROL | Diabetes Mellitus, Experimental - drug therapy | Chemoreceptor Cells - drug effects | Rats, Wistar | Sympathetic Nervous System - drug effects | Cardiovascular Diseases - drug therapy | Male | Sympathetic Nervous System - physiopathology | Hyperglycemia - drug therapy | Heart Rate - drug effects | Peptidyl-Dipeptidase A - metabolism | Blood Pressure - drug effects | Blood Pressure - physiology | Parasympathetic Nervous System - physiopathology | Diabetes Mellitus, Experimental - metabolism | Hyperglycemia - physiopathology | Diabetes Mellitus, Experimental - physiopathology | Heart - physiopathology | Tachycardia - drug therapy | Vasoconstrictor Agents - pharmacology | Cardiovascular Diseases - physiopathology | Autonomic Nervous System Diseases - metabolism | Cardiovascular Diseases - metabolism | Bradycardia - physiopathology | Rats | Chemoreceptor Cells - physiology | Tachycardia - physiopathology | Vasoconstriction - drug effects | Baroreflex - drug effects | Animals | Autonomic Nervous System Diseases - physiopathology | Autonomic Nervous System Diseases - drug therapy | Parasympathetic Nervous System - drug effects | Heart - drug effects | Baroreflex - physiology | Bradycardia - drug therapy | Chemoreflex | ACE2 activation | Baroreflex
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