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The FEBS journal, ISSN 1742-464X, 05/2017, Volume 284, Issue 9, pp. 1267 - 1278
endosome | PI3P | autophagosome | lysosome | membrane trafficking | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Endoplasmic Reticulum - enzymology | Class II Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol Phosphates - metabolism | Endosomes - physiology | Membrane Microdomains - enzymology | Autophagosomes - physiology | Humans | Autophagosomes - enzymology | Endoplasmic Reticulum - physiology | Class III Phosphatidylinositol 3-Kinases - metabolism | Lysosomes - enzymology | Adaptor Proteins, Vesicular Transport - metabolism | Autophagy | Lysosomes - physiology | Organelle Biogenesis | Animals | Models, Biological | Endosomes - enzymology | Membrane Microdomains - physiology | Beclin-1 - metabolism | Autophagy-Related Proteins - metabolism | Second Messenger Systems | Phosphates | Phospholipids | Protein binding | Membranes | Phagosomes | Lipids | Biosynthesis | Kinases | Machinery | Proteins | Lipid kinase | Membrane trafficking | Endoplasmic reticulum | Phagocytosis | Index Medicus
Journal Article
The Journal of cell biology, ISSN 0021-9525, 07/2017, Volume 216, Issue 7, pp. 1937 - 1947
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Humans | Autophagosomes - enzymology | Lysosomes - enzymology | rab GTP-Binding Proteins - genetics | Drosophila Proteins - metabolism | Autophagy | Drosophila melanogaster - genetics | Breast Neoplasms - enzymology | Endocytosis | Transfection | RNA Interference | Proteolysis | Female | rab2 GTP-Binding Protein - metabolism | rab GTP-Binding Proteins - metabolism | Membrane Fusion | Signal Transduction | Animals, Genetically Modified | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | rab2 GTP-Binding Protein - genetics | Cell Line, Tumor | Drosophila melanogaster - enzymology | Endosomes - enzymology | Drosophila Proteins - genetics | Cellular proteins | Autophagy (Cytology) | Genetic aspects | Gene expression | Health aspects | Biodegradation | Cargo | Yeast | Maturation | Phagosomes | Lysosomes | Guanosine triphosphatases | Tethering | Breast cancer | Cells | Degradation | Guanosine triphosphate | Fruit flies | Binding sites | Endosomes | Index Medicus
Journal Article
Autophagy, ISSN 1554-8627, 04/2019, Volume 15, Issue 4, pp. 631 - 651
autophagy | neurodegeneration | spinal and bulbar muscular atrophy | TFEB | Amyotrophic lateral sclerosis | motoneuron diseases | trehalose | lactulose | calcineurin | protein quality control | lysosomes | melibiose | galectin-3 | Life Sciences & Biomedicine | Science & Technology | Cell Biology | RNA, Small Interfering - genetics | Calcium - metabolism | Microtubule-Associated Proteins - metabolism | Humans | Autophagosomes - enzymology | Lysosomes - enzymology | Amyotrophic Lateral Sclerosis - drug therapy | Autophagy - drug effects | Motor Neurons - pathology | Motor Neurons - ultrastructure | Neuroprotection - drug effects | Autophagosomes - drug effects | Calcineurin - genetics | Cell Nucleus - metabolism | Lysosomes - metabolism | Trehalose - analogs & derivatives | Cell Differentiation | Membrane Proteins - metabolism | Autophagy - genetics | Autophagy-Related Proteins - genetics | Sequestosome-1 Protein - metabolism | Induced Pluripotent Stem Cells - metabolism | Induced Pluripotent Stem Cells - pathology | Lysosomes - drug effects | Induced Pluripotent Stem Cells - enzymology | Unfolded Protein Response - genetics | Membrane Proteins - genetics | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - chemistry | Induced Pluripotent Stem Cells - ultrastructure | Signal Transduction - genetics | Autophagosomes - metabolism | Bulbo-Spinal Atrophy, X-Linked - metabolism | Motor Neurons - enzymology | Neuroprotection - genetics | Bulbo-Spinal Atrophy, X-Linked - drug therapy | Down-Regulation - genetics | Lysosomes - ultrastructure | Motor Neurons - metabolism | Animals | Signal Transduction - drug effects | Amyotrophic Lateral Sclerosis - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Mice | Autophagy-Related Proteins - metabolism | Calcineurin - metabolism | RNA, Small Interfering - metabolism | Trehalose - pharmacology | Index Medicus
Journal Article
Molecular cell, ISSN 1097-2765, 09/2017, Volume 67, Issue 6, pp. 974 - 989.e6
VMP1 | membrane contact | SERCA | autophagosome | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Intracellular Membranes - enzymology | Phosphatidylinositol Phosphates - metabolism | Humans | Proteolipids - metabolism | Autophagosomes - enzymology | Caenorhabditis elegans Proteins - metabolism | Cercopithecus aethiops | Autophagy-Related Protein-1 Homolog - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Transfection | RNA Interference | HEK293 Cells | Muscle Proteins - metabolism | Membrane Proteins - metabolism | Lipid Droplets - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Calcium-Binding Proteins - metabolism | Endoplasmic Reticulum - enzymology | Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism | Animals, Genetically Modified | Caenorhabditis elegans - genetics | Membrane Proteins - genetics | Genotype | Phenotype | Animals | CRISPR-Cas Systems | HeLa Cells | Sarcoplasmic Reticulum Calcium-Transporting ATPases - genetics | Autophagy-Related Protein-1 Homolog - genetics | COS Cells | Caenorhabditis elegans Proteins - genetics | Caenorhabditis elegans - enzymology | Calcium-binding proteins | Cells | Adenosine triphosphatase | Index Medicus
Journal Article
Molecular cell, ISSN 1097-2765, 03/2017, Volume 65, Issue 5, pp. 917 - 931.e6
ARD1 | autophagy | tumor | PGK1 | mTOR | Beclin1 | VPS34 | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Glioblastoma - enzymology | Glutamine - deficiency | Phosphorylation | Cell Proliferation | TOR Serine-Threonine Kinases - metabolism | Humans | Autophagosomes - enzymology | Brain Neoplasms - pathology | Autophagy | Tumor Hypoxia | TOR Serine-Threonine Kinases - genetics | Transfection | Glioblastoma - genetics | RNA Interference | Time Factors | HEK293 Cells | Female | Acetylation | Phosphoglycerate Kinase - genetics | Brain Neoplasms - enzymology | Signal Transduction | N-Terminal Acetyltransferase A - genetics | Brain Neoplasms - genetics | Class III Phosphatidylinositol 3-Kinases - metabolism | Tumor Burden | Autophagosomes - pathology | Animals | N-Terminal Acetyltransferase A - metabolism | Class III Phosphatidylinositol 3-Kinases - genetics | Mice, Nude | Glioblastoma - pathology | Beclin-1 - genetics | Cell Line, Tumor | N-Terminal Acetyltransferase E - genetics | Protein Binding | Beclin-1 - metabolism | N-Terminal Acetyltransferase E - metabolism | Phosphoglycerate Kinase - metabolism | Enzymes | Medical colleges | Gliomas | Pancreatic cancer | Brain tumors | Physiological aspects | Phospholipids | Protein kinases | Glutamine | Index Medicus
Journal Article
Molecular cell, ISSN 1097-2765, 03/2017, Volume 65, Issue 6, pp. 1029 - 1043.e5
Stx-17 | UVRAG | PI3KC3 | Rubicon | Vps34 | Beclin1 | Pacer | HOPS | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Protein Aggregates | Salmonella typhimurium - growth & development | Vesicular Transport Proteins - metabolism | Humans | Autophagosomes - enzymology | Lysosomes - enzymology | Intracellular Signaling Peptides and Proteins - metabolism | Autophagy | Transfection | RNA Interference | Time Factors | Tumor Suppressor Proteins - genetics | HEK293 Cells | Qa-SNARE Proteins - genetics | Protein Interaction Domains and Motifs | Lipid Droplets - metabolism | Autophagy-Related Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Tumor Suppressor Proteins - metabolism | Membrane Fusion | Signal Transduction | Vesicular Transport Proteins - genetics | Class III Phosphatidylinositol 3-Kinases - metabolism | Hep G2 Cells | Host-Pathogen Interactions | Qa-SNARE Proteins - metabolism | Protein Binding | Endosomes - enzymology | Enzyme Activation | HeLa Cells | Autophagy-Related Proteins - metabolism | Hepatocytes - enzymology | Molecular biology | Medical colleges | Health aspects | Index Medicus
Journal Article
Nature cell biology, ISSN 1465-7392, 04/2020, Volume 22, Issue 4, pp. 412 - 424
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Fibroblasts - enzymology | Cell Proliferation | Adenocarcinoma of Lung - pathology | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Autophagosomes - enzymology | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Autophagy-Related Protein 5 - genetics | Autophagy-Related Protein-1 Homolog - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Adenocarcinoma of Lung - genetics | Proto-Oncogene Proteins p21(ras) - deficiency | Copper - metabolism | Autophagy - genetics | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Lung Neoplasms - genetics | Amino Acid Sequence | Lung Neoplasms - enzymology | Signal Transduction | Cell Survival | Protein-Serine-Threonine Kinases - genetics | Copper Transporter 1 - genetics | Adenocarcinoma of Lung - enzymology | Fibroblasts - pathology | Mice, Knockout | Sequence Homology, Amino Acid | Xenograft Model Antitumor Assays | Sequence Alignment | Animals | Autophagy-Related Protein 5 - deficiency | Cell Line, Tumor | Copper Transporter 1 - deficiency | Mice | Autophagy-Related Protein-1 Homolog - genetics | Adenocarcinoma | Autophagy (Cytology) | Enzymes | Lung cancer | Oncology, Experimental | Development and progression | Research | Physiological aspects | Regulation | Copper | Health aspects | Protein kinases | Cancer | Binding | Transition metals | Starvation | Intracellular signalling | Kinases | Autophagy | Survival | Signaling | Lungs | Chelation | Mutation | Transporter | Phagocytosis | Tumors | Index Medicus
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 03/2015, Volume 290, Issue 13, pp. 8146 - 8153
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Green Fluorescent Proteins - metabolism | Vacuoles - enzymology | Autophagy-Related Proteins | Intracellular Membranes - enzymology | Phagosomes - enzymology | Autophagy | Recombinant Fusion Proteins - metabolism | Protein Transport | Phosphatidylethanolamines | Ubiquitin-Conjugating Enzymes - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Saccharomyces cerevisiae - enzymology | Microscopy, Fluorescence | Index Medicus | Biodegradation | Atg3 | Atg8 Lipidation | Yeast | Organelle | Isolation Membrane | Autophagosome | Saccharomyces cerevisiae | Cell Biology
Journal Article
The Journal of cell biology, ISSN 0021-9525, 02/2017, Volume 216, Issue 2, pp. 441 - 461
Axonal Transport | Axons - enzymology | Autophagosomes - enzymology | Multiprotein Complexes - genetics | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Recombinant Fusion Proteins - metabolism | Multiprotein Complexes - metabolism | Transfection | RNA Interference | Protein Interaction Domains and Motifs | Secretory Vesicles - enzymology | Dyneins - metabolism | Cell Line | Signal Transduction | Animals, Genetically Modified | Protein Phosphatase 2 - genetics | Genotype | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Phenotype | Animals | Adaptor Proteins, Signal Transducing - genetics | Protein Phosphatase 2 - metabolism | Drosophila melanogaster - enzymology | Presynaptic Terminals - metabolism | Protein Binding | Recombinant Fusion Proteins - genetics | Drosophila Proteins - genetics | Dyneins - genetics | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Microscopy, Fluorescence | Proteins | Homeostasis | Cellular biology | Neurodegeneration | Neurons | Autophagy | Index Medicus
Journal Article