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PloS one, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, pp. e0173676 - e0173676
.... Chronic administration of the PPARa agonist FB substantially reduced the levels of multiple autophagy proteins in the liver... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | TOR Serine-Threonine Kinases - metabolism | Autophagy-Related Protein 7 - metabolism | Fibroblast Growth Factors - genetics | Autophagy-Related Protein 5 - genetics | fas Receptor - metabolism | Autophagy - drug effects | Fibroblast Growth Factors - metabolism | TOR Serine-Threonine Kinases - genetics | Liver - drug effects | fas Receptor - genetics | Autophagy - genetics | Proto-Oncogene Proteins c-akt - metabolism | Forkhead Box Protein O1 - metabolism | Signal Transduction | Liver - metabolism | PPAR alpha - genetics | Ubiquitin-Conjugating Enzymes - genetics | Stearoyl-CoA Desaturase - genetics | Mice, Knockout | Triglycerides - metabolism | Sequestosome-1 Protein - genetics | Ubiquitin-Conjugating Enzymes - metabolism | Cysteine Endopeptidases - genetics | Autophagy-Related Protein 5 - metabolism | Beclin-1 - genetics | Stearoyl-CoA Desaturase - metabolism | Mice | PPAR alpha - metabolism | Autophagy-Related Proteins - antagonists & inhibitors | Blood Glucose - metabolism | Autophagy-Related Proteins - metabolism | Forkhead Box Protein O1 - genetics | Autophagy-Related Protein 5 - antagonists & inhibitors | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Proto-Oncogene Proteins c-akt - genetics | Fenofibrate - pharmacology | Cysteine Endopeptidases - metabolism | Autophagy-Related Proteins - genetics | Sequestosome-1 Protein - metabolism | Sterol Regulatory Element Binding Protein 1 - metabolism | Autophagy-Related Protein 7 - antagonists & inhibitors | Mice, Inbred C57BL | Autophagy-Related Protein 7 - genetics | Gene Expression Regulation - drug effects | Animals | Sterol Regulatory Element Binding Protein 1 - genetics | PPAR alpha - agonists | Ubiquitin-Conjugating Enzymes - antagonists & inhibitors | Beclin-1 - metabolism | Transcription factors | Adipose tissue | Liver | Body weight | AKT protein | Biochemistry | Glucose | Assaying | Proteins | Signal transduction | Temperature effects | Fibroblasts | Physiology | Acetylation | Inhibition | Growth factors | Hepatotoxicity | Activation analysis | Methanol | Starvation | Ethanol | AMP | Metabolism | Insulin | Fatty acids | Studies | Acetaminophen | Food intake | Weight reduction | Animal welfare | Circulation | Drugs | Biotechnology | Drug abuse | Laboratories | Centrifugation | Glass | Homeostasis | Activation | Biology | Kinases | AMP-activated protein kinase | Autophagy | Nutrient status | Rodents | Nutrients | Oxidation | Heart diseases | Age | Epinephrine | AKT1 protein | Fasting | Chloroform | Diabetes mellitus | Cardiomyocytes | Acclimatization | Triglycerides | Pharmacology | Nitrogen | Calories | Medicine | Nuclear fuels | Protein kinase | Insulin resistance | Diabetes | Index Medicus
Journal Article
Cancer research (Chicago, Ill.), ISSN 0008-5472, 12/2009, Volume 69, Issue 23, pp. 8844 - 8852
.... TGF-beta induced accumulation of autophagosomes and conversion of microtubule-associated protein I light chain 3 and enhanced the degradation rate of long-lived proteins... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Microtubule-Associated Proteins - genetics | Humans | Ubiquitin-Activating Enzymes - biosynthesis | Cell Growth Processes - physiology | JNK Mitogen-Activated Protein Kinases - metabolism | Autophagy - physiology | Proto-Oncogene Proteins - biosynthesis | Transforming Growth Factor beta - biosynthesis | Breast Neoplasms - metabolism | Transfection | Bcl-2-Like Protein 11 | Carcinoma, Hepatocellular - genetics | Apoptosis Regulatory Proteins - genetics | Liver Neoplasms - pathology | Apoptosis Regulatory Proteins - biosynthesis | Beclin-1 | Ubiquitin-Activating Enzymes - genetics | Liver Neoplasms - genetics | Membrane Proteins - genetics | Transforming Growth Factor beta - physiology | Proto-Oncogene Proteins - genetics | Microtubule-Associated Proteins - antagonists & inhibitors | Microtubule-Associated Proteins - biosynthesis | Autophagy-Related Protein 7 | Membrane Proteins - biosynthesis | Breast Neoplasms - genetics | Transforming Growth Factor beta - genetics | Autophagy-Related Protein 5 | Membrane Proteins - antagonists & inhibitors | Receptors, Transforming Growth Factor beta - metabolism | Breast Neoplasms - pathology | Ubiquitin-Activating Enzymes - antagonists & inhibitors | Adaptor Proteins, Signal Transducing - genetics | Apoptosis Regulatory Proteins - antagonists & inhibitors | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Cell Line, Tumor | Adaptor Proteins, Signal Transducing - biosynthesis | Smad Proteins - metabolism | Carcinoma, Hepatocellular - metabolism | Index Medicus
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 10/2012, Volume 287, Issue 42, pp. 35576 - 35588
...), and caused a punctate fluorescence pattern with the GFP-LC3 protein, which all are markers for cellular autophagy... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Transcription, Genetic - drug effects | Reactive Oxygen Species - metabolism | Microtubule-Associated Proteins - genetics | Humans | Ubiquitin-Activating Enzymes - biosynthesis | Male | Extracellular Signal-Regulated MAP Kinases - metabolism | Neoplasm Proteins - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Autophagy - drug effects | Benzylisoquinolines - chemistry | Dose-Response Relationship, Drug | Carcinoma, Hepatocellular - drug therapy | MAP Kinase Signaling System - genetics | Mitochondria - genetics | Carcinoma, Hepatocellular - genetics | Liver Neoplasms - pathology | Autophagy - genetics | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Stephania tetrandra - chemistry | Antineoplastic Agents, Phytogenic - pharmacokinetics | Benzylisoquinolines - pharmacology | Gene Expression Regulation, Neoplastic - genetics | Ubiquitin-Activating Enzymes - genetics | Liver Neoplasms - genetics | Liver Neoplasms - drug therapy | Antineoplastic Agents, Phytogenic - chemistry | Mitochondria - metabolism | Mitochondria - pathology | Microtubule-Associated Proteins - biosynthesis | Hep G2 Cells | Xenograft Model Antitumor Assays | Autophagy-Related Protein 7 | Animals | MAP Kinase Signaling System - drug effects | Mice, Nude | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Mice | Mice, Inbred BALB C | Transcription, Genetic - genetics | Carcinoma, Hepatocellular - metabolism | Index Medicus | Gene Regulation | Cancer Therapy | Autophagy-related Gene 7 (ATG7) | Tetrandrine | Reactive Oxygen Species (ROS) | Signal Transduction | Autophagy | Anticancer Drug | ERK | Hepatocellular Carcinoma
Journal Article
Nature cell biology, ISSN 1476-4679, 04/2014, Volume 16, Issue 5, pp. 415 - 424
Journal Article
Journal Article
Autophagy, ISSN 1554-8635, 09/2018, Volume 15, Issue 3, pp. 453 - 465
... intracellular environment by degrading toxic aggregates, misfolded proteins, and damaged organelles [2]. Dysregulation of autophagy is implicated in many diseases... 
retinitis pigmentosa | CERKL | stabilization | Autophagy | SIRT1 | deacetylation | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Index Medicus
Journal Article
EMBO reports, ISSN 1469-3178, 01/2009, Volume 10, Issue 2, pp. 173 - 179
Ubiquilins (UBQLNs) are adaptor proteins thought to deliver ubiquitinated substrates to proteasomes... 
ubiquitin‐like | PLIC | autophagy | ubiquilin | autophagosomes | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Ubiquitin-Activating Enzymes - physiology | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Ubiquitins - genetics | Humans | Adaptor Proteins, Vesicular Transport - genetics | Recombinant Fusion Proteins - physiology | Autophagy - physiology | Autophagy - drug effects | Microscopy, Immunoelectron | Cell Cycle Proteins - antagonists & inhibitors | Recombinant Fusion Proteins - antagonists & inhibitors | RNA Interference | Cell Cycle Proteins - genetics | Carrier Proteins - physiology | Protein Structure, Tertiary | Ubiquitin-Activating Enzymes - genetics | Adaptor Proteins, Vesicular Transport - physiology | Adaptor Proteins, Vesicular Transport - antagonists & inhibitors | Phagosomes - metabolism | Carrier Proteins - antagonists & inhibitors | RNA, Small Interfering - physiology | Microtubule-Associated Proteins - antagonists & inhibitors | Ubiquitins - physiology | HeLa Cells - drug effects | Microtubule-Associated Proteins - physiology | Protein Interaction Mapping | Carrier Proteins - genetics | Autophagy-Related Protein 7 | Animals | Autophagy-Related Protein 5 | Ubiquitin-Activating Enzymes - antagonists & inhibitors | Culture Media - pharmacology | Mice | HeLa Cells - cytology | Cell Cycle Proteins - physiology | Ubiquitins - antagonists & inhibitors | Proteins | Genetics | Nutrients | Molecular biology | Substrates | Index Medicus | ubiquitin-like | Scientific Report
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 08/2017, Volume 292, Issue 33, pp. 13795 - 13808
.... Here, we report that phosphorylation of autophagy-associated protein p62 by AMP-activated protein kinase (AMPK... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | AMP-Activated Protein Kinases - metabolism | Autophagy-Related Protein 7 - metabolism | Humans | Protein Transport - drug effects | Hippocampus - drug effects | Neural Stem Cells - cytology | Recombinant Fusion Proteins - metabolism | Autophagy - drug effects | Protein Processing, Post-Translational - drug effects | RNA Interference | Gene Deletion | Phosphorylation - drug effects | Sequestosome-1 Protein - metabolism | Adult Stem Cells - drug effects | Autophagy-Related Protein 7 - antagonists & inhibitors | Cell Survival - drug effects | Nerve Tissue Proteins - antagonists & inhibitors | Adult Stem Cells - cytology | AMP-Activated Protein Kinases - antagonists & inhibitors | Sequestosome-1 Protein - antagonists & inhibitors | Cells, Cultured | Neural Stem Cells - drug effects | Rats | Recombinant Fusion Proteins - chemistry | Enzyme Activation - drug effects | Hippocampus - cytology | Autophagy-Related Protein 7 - genetics | Nerve Tissue Proteins - genetics | AMP-Activated Protein Kinases - chemistry | Nerve Tissue Proteins - metabolism | Hippocampus - metabolism | Point Mutation | Sequestosome-1 Protein - genetics | Adult Stem Cells - metabolism | Animals | Protein Kinase Inhibitors - pharmacology | Neural Stem Cells - metabolism | AMP-Activated Protein Kinases - genetics | Amino Acid Substitution | Index Medicus | AMP-activated kinase (AMPK) | mitophagy | autophagy | phosphorylation | p62 (sequestosome 1 (SQSTM1)) | Protein Synthesis and Degradation
Journal Article
Journal Article