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Nature (London), ISSN 1476-4687, 03/2019, Volume 567, Issue 7747, pp. 262 - 266
Cyclic GMP-AMP (cGAMP) synthase (cGAS) detects infections or tissue damage by binding to microbial or self DNA in the cytoplasm(1). Upon binding DNA, cGAS... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Nucleotides, Cyclic - metabolism | Interferons - biosynthesis | Beclin-1 - deficiency | Vesicular Transport Proteins - metabolism | Humans | Endoplasmic Reticulum - metabolism | Autophagy-Related Protein 5 - genetics | Autophagy-Related Protein-1 Homolog - metabolism | DNA Viruses - metabolism | Interferons - immunology | Autophagy | DNA Viruses - genetics | Sea Anemones | Membrane Proteins - deficiency | HEK293 Cells | Membrane Proteins - metabolism | Nucleotidyltransferases - metabolism | Protein-Serine-Threonine Kinases - metabolism | Phosphate-Binding Proteins | Signal Transduction | Membrane Proteins - genetics | DNA, Viral - metabolism | Class III Phosphatidylinositol 3-Kinases - metabolism | Autophagosomes - metabolism | Cytosol - virology | Protein Transport | Carrier Proteins - genetics | Animals | Autophagy-Related Protein-1 Homolog - deficiency | Carrier Proteins - metabolism | Monomeric GTP-Binding Proteins - metabolism | Autophagy-Related Protein 5 - deficiency | Autophagy-Related Protein 5 - metabolism | Beclin-1 - genetics | Golgi Apparatus - metabolism | Mice | Beclin-1 - metabolism | Autophagy-Related Protein-1 Homolog - genetics | Nucleotides, Cyclic - immunology | Evolution, Molecular | Biological research | Autophagy (Cytology) | Enzymes | Physiological aspects | Interferon | Research | Cytoplasm | Biology, Experimental | Index Medicus
Journal Article
Annual review of biochemistry, ISSN 0066-4154, 6/2017, Volume 86, Issue 1, pp. 225 - 244
Autophagy is the process of cellular self-eating by a double-membrane organelle, the autophagosome. A range of signaling processes converge on two protein... 
COPII | Atg1 | membrane remodeling | vesicle | tethering complex | nanoscale biology | ULK1 | Vps34 | membrane fusion | phosphatidylinositol 3-kinase | Vesicle | Membrane fusion | Membrane remodeling | Phosphatidylinositol 3-kinase | Nanoscale biology | Tethering complex | Humans | Protein Multimerization | Eukaryotic Cells - metabolism | Autophagy-Related Protein-1 Homolog - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Eukaryotic Cells - ultrastructure | Class III Phosphatidylinositol 3-Kinases - chemistry | Phagosomes - ultrastructure | Cell Membrane - metabolism | Autophagy - genetics | Intracellular Signaling Peptides and Proteins - genetics | Phosphatidylinositol 3-Kinase - metabolism | COP-Coated Vesicles - ultrastructure | Gene Expression | Signal Transduction | Phagosomes - metabolism | Gene Expression Regulation | COP-Coated Vesicles - metabolism | Class III Phosphatidylinositol 3-Kinases - metabolism | Cell Membrane - ultrastructure | Autophagy-Related Protein-1 Homolog - chemistry | Phosphatidylinositol 3-Kinase - chemistry | Phosphatidylinositol 3-Kinase - genetics | Class III Phosphatidylinositol 3-Kinases - genetics | Intracellular Signaling Peptides and Proteins - chemistry | Protein Binding | Autophagy-Related Protein-1 Homolog - genetics | Physiological aspects | Autophagy (Cytology) | Genetic aspects | Research | Gene expression | Index Medicus
Journal Article
Biochemical journal, ISSN 1470-8728, 02/2019, Volume 476, Issue 3, pp. 535 - 546
Journal Article
The Journal of clinical investigation, ISSN 1558-8238, 01/2019, Volume 129, Issue 2, pp. 802 - 819
Journal Article