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Autophagy, ISSN 1554-8635, 10/2014, Volume 7, Issue 12, pp. 1448 - 1461
.... Previously, we identified the human WIPI protein family and found that WIPI-1 specifically binds PtdIns(3... 
WIPI-1 | Atg18 | PtdInsP | LC3 | resveratrol | noncanonical autophagy | Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Autophagy-Related Protein 12 | Cell Line | Autophagy-Related Proteins | Small Ubiquitin-Related Modifier Proteins/metabolism | Phosphatidylinositol Phosphates/metabolism | Protein Transport/drug effects | Humans | Autophagy/drug effects | Lipids/chemistry | Green Fluorescent Proteins/metabolism | Autophagy-Related Protein 7 | Animals | Autophagy-Related Protein 5 | Membrane Proteins/metabolism | Carrier Proteins/drug effects | Wortmannin | Resveratrol | Androstadienes/pharmacology | Stilbenes/pharmacology | Mice | Recombinant Fusion Proteins/metabolism | Phagosomes/drug effects | Ubiquitin-Activating Enzymes/metabolism | Microtubule-Associated Proteins/metabolism | Noncanonical autophagy | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Phosphatidylinositol Phosphates - metabolism | Microtubule-Associated Proteins - metabolism | Protein Transport - drug effects | Stilbenes - pharmacology | Carrier Proteins - drug effects | Recombinant Fusion Proteins - metabolism | Autophagy - drug effects | Lipids - chemistry | Phagosomes - ultrastructure | Membrane Proteins - metabolism | Phagosomes - drug effects | Green Fluorescent Proteins - metabolism | Small Ubiquitin-Related Modifier Proteins - metabolism | Phagosomes - metabolism | Ubiquitin-Activating Enzymes - metabolism | Carrier Proteins - metabolism | Androstadienes - pharmacology | Index Medicus | Basic Research-Paper | Basic Research Paper
Journal Article
Journal of Applied Physiology, ISSN 8750-7587, 05/2012, Volume 112, Issue 9, pp. 1529 - 1537
...), and mitochondrial remodeling including mitophagy was assessed by measuring protein markers during ultra-endurance running exercise in human skeletal muscle... 
Muscle protein degradation | Mitochondrial remodelling | Mitophagy | LC3b | MuRF1 | Physiology | Sport Sciences | Life Sciences & Biomedicine | Science & Technology | Protein Kinases - metabolism | AMP-Activated Protein Kinases - metabolism | Phosphorylation | TOR Serine-Threonine Kinases - metabolism | Microtubule-Associated Proteins - metabolism | Humans | Middle Aged | Serine | Ubiquitin - metabolism | Male | Physical Endurance | Insulin - blood | Phosphoproteins - metabolism | Autophagy | Tripartite Motif Proteins | Quadriceps Muscle - enzymology | Time Factors | Forkhead Transcription Factors - metabolism | Mitochondrial Proteins - metabolism | Muscle Proteins - metabolism | Adult | Proto-Oncogene Proteins c-akt - metabolism | Quadriceps Muscle - pathology | Autophagy-Related Protein 12 | Mitochondrial Membrane Transport Proteins - metabolism | Mitochondria, Muscle - enzymology | Signal Transduction | Mitochondria, Muscle - pathology | Small Ubiquitin-Related Modifier Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | SKP Cullin F-Box Protein Ligases - metabolism | Energy Intake | GTP Phosphohydrolases - metabolism | Autophagy-Related Protein 5 | Energy Metabolism | Biopsy | Running | Proteasome Endopeptidase Complex - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Blood Glucose - metabolism | Forkhead Box Protein O3 | Proteins | Musculoskeletal system | Signal transduction | Athletes | Index Medicus
Journal Article
Journal Article
Journal Article
Nature (London), ISSN 1476-4687, 03/2019, Volume 567, Issue 7747, pp. 262 - 266
...). Upon binding DNA, cGAS produces cGAMP that binds to and activates the adaptor protein STING, which then activates the kinases IKK and TBK1 to induce interferons and other cytokines(2-6... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Nucleotides, Cyclic - metabolism | Interferons - biosynthesis | Beclin-1 - deficiency | Vesicular Transport Proteins - metabolism | Humans | Endoplasmic Reticulum - metabolism | Autophagy-Related Protein 5 - genetics | Autophagy-Related Protein-1 Homolog - metabolism | DNA Viruses - metabolism | Interferons - immunology | Autophagy | DNA Viruses - genetics | Sea Anemones | Membrane Proteins - deficiency | HEK293 Cells | Membrane Proteins - metabolism | Nucleotidyltransferases - metabolism | Protein-Serine-Threonine Kinases - metabolism | Phosphate-Binding Proteins | Signal Transduction | Membrane Proteins - genetics | DNA, Viral - metabolism | Class III Phosphatidylinositol 3-Kinases - metabolism | Autophagosomes - metabolism | Cytosol - virology | Protein Transport | Carrier Proteins - genetics | Animals | Autophagy-Related Protein-1 Homolog - deficiency | Carrier Proteins - metabolism | Monomeric GTP-Binding Proteins - metabolism | Autophagy-Related Protein 5 - deficiency | Autophagy-Related Protein 5 - metabolism | Beclin-1 - genetics | Golgi Apparatus - metabolism | Mice | Beclin-1 - metabolism | Autophagy-Related Protein-1 Homolog - genetics | Nucleotides, Cyclic - immunology | Evolution, Molecular | Biological research | Autophagy (Cytology) | Enzymes | Physiological aspects | Interferon | Research | Cytoplasm | Biology, Experimental | Index Medicus
Journal Article
Journal Article
Nature cell biology, ISSN 1476-4679, 06/2015, Volume 17, Issue 7, pp. 893 - 906
.... This allows for the sustained localization of PtdIns(3)P, which is critical for recruitment of downstream autophagic proteins and stabilization of the NOX2 complex to produce reactive oxygen species. Both PtdIns(3... 
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Phagosomes - microbiology | Autophagy-Related Proteins | Phosphatidylinositol Phosphates - metabolism | Reactive Oxygen Species - metabolism | Membrane Glycoproteins - metabolism | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Vesicular Transport Proteins - metabolism | NADPH Oxidases - metabolism | Immunoblotting | Male | Green Fluorescent Proteins - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Autophagy | RNA Interference | Tumor Suppressor Proteins - genetics | Aspergillus fumigatus - physiology | NADPH Oxidases - genetics | Female | Intracellular Signaling Peptides and Proteins - genetics | Macrophages - microbiology | Cell Line | Green Fluorescent Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Mice, Inbred C57BL | Phagosomes - metabolism | Vesicular Transport Proteins - genetics | Class III Phosphatidylinositol 3-Kinases - metabolism | Mice, Transgenic | NADPH Oxidase 2 | Membrane Glycoproteins - genetics | Mice, Knockout | Host-Pathogen Interactions | Microscopy, Confocal | Macrophages - metabolism | Animals | Phagocytosis | Cellular proteins | Development and progression | Genetic aspects | Properties | Communicable diseases | Index Medicus
Journal Article
Cell death & disease, ISSN 2041-4889, 03/2017, Volume 8, Issue 3, pp. e2716 - e2716
Journal Article
Journal Article