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Scientific Reports, ISSN 2045-2322, 02/2016, Volume 6, Issue 1, p. 22113
Journal Article
Journal Article
PLoS Genetics, ISSN 1553-7390, 04/2018, Volume 14, Issue 4, p. e1007339
Wnt signaling provides a paradigm for cell-cell signals that regulate embryonic development and stem cell homeostasis and are inappropriately activated in... 
DISHEVELLED PROTEIN | PATHWAY ACTIVATION | AXIN | ADENOMATOUS POLYPOSIS-COLI | TUMOR-SUPPRESSOR APC | OVERLAPPING ROLES | DEP DOMAIN | NEGATIVE REGULATION | GENETICS & HEREDITY | DROSOPHILA APC2 | DIX DOMAIN | Wnt1 Protein - genetics | Drosophila melanogaster - embryology | Transcription Factors - chemistry | Axin Protein - genetics | Axin Protein - chemistry | Multiprotein Complexes - genetics | Wnt1 Protein - metabolism | Armadillo Domain Proteins - genetics | Drosophila Proteins - metabolism | RNA, Messenger - metabolism | Drosophila melanogaster - genetics | Recombinant Fusion Proteins - metabolism | Axin Protein - metabolism | Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome - metabolism | Drosophila melanogaster - metabolism | Multiprotein Complexes - metabolism | Proteolysis | Tumor Suppressor Proteins - chemistry | Tumor Suppressor Proteins - genetics | Transcription, Genetic | Wnt Signaling Pathway | Axin Signaling Complex - chemistry | Cell Line | Tumor Suppressor Proteins - metabolism | Animals, Genetically Modified | RNA, Messenger - genetics | Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome - genetics | Armadillo Domain Proteins - chemistry | Drosophila Proteins - chemistry | Recombinant Fusion Proteins - chemistry | Transcription Factors - genetics | Glycogen Synthase Kinase 3 - metabolism | Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome - chemistry | Transcription Factors - metabolism | Multiprotein Complexes - chemistry | Animals | Axin Signaling Complex - metabolism | Glycogen Synthase Kinase 3 - genetics | Axin Signaling Complex - genetics | Armadillo Domain Proteins - metabolism | Recombinant Fusion Proteins - genetics | Drosophila Proteins - genetics | Binding proteins | Wnt proteins | Health aspects | Stoichiometry | Phosphorylation | Wnt protein | Funding | Glycogen synthase | Genes | Homeostasis | Kinases | Proteins | β-catenin | Embryogenesis | Ubiquitination | Localization | Dishevelled protein | Glycogen | Polymerization | Curricula | Embryos | Adenomatous polyposis coli | Microscopy | Insects | Stem cells | Regulation | Genetic engineering | Molecular biology | Cancer
Journal Article
Carcinogenesis, ISSN 0143-3334, 05/2013, Volume 34, Issue 5, pp. 953 - 961
Carcinoid tumors are rare neuroendocrine tumors (NETs) that are increasing in incidence. Mutation and altered expression of Wnt/-catenin signaling components... 
PROMOTER HYPERMETHYLATION | INHIBITORY FACTOR-I | DNA METHYLATION | SUPPRESSOR GENE | ONCOLOGY | GASTRIC-CANCER | GASTROINTESTINAL CARCINOID-TUMOR | COLORECTAL-CANCER | E1317Q VARIANT | BETA-CATENIN | HISTONE MODIFICATIONS | Axin Protein - genetics | Gene Expression - genetics | Epigenesis, Genetic | Humans | Cytoplasm - metabolism | Male | DNA Mutational Analysis - methods | Wnt Proteins - metabolism | Axin Protein - metabolism | Genes, APC | TCF Transcription Factors - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | DNA Methylation | Cell Nucleus - metabolism | Wnt Proteins - genetics | Epigenomics - methods | Cytoplasm - genetics | Membrane Proteins - metabolism | Genes, Tumor Suppressor | Repressor Proteins - metabolism | Membrane Proteins - genetics | Neuroendocrine Tumors - metabolism | Intercellular Signaling Peptides and Proteins - genetics | Repressor Proteins - genetics | Signal Transduction - genetics | beta Catenin - metabolism | beta Catenin - genetics | Neuroendocrine Tumors - genetics | Animals | Cell Nucleus - genetics | Mice, Nude | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | CpG Islands | Mice | Mutation | Transcription, Genetic - genetics | Adaptor Proteins, Signal Transducing - metabolism | TCF Transcription Factors - genetics | 5-aza-2'-deoxycytidine | Original Manuscript
Journal Article
Biochemical Society Symposium, ISSN 0067-8694, 06/2013, Volume 41, Issue 3, pp. 727 - 740
Vertebrate DNA can be chemically modified by methylation of the 5 position of the cytosine base in the context of CpG dinucleotides. This modification creates... 
DNA methylation | Epigenetics | DNA demethylation | Chromatin | Transcription | CpG island | transcription | BIOCHEMISTRY & MOLECULAR BIOLOGY | BINDING-PROTEIN | TRANSCRIPTIONAL REPRESSION | chromatin | H3-LYS METHYLTRANSFERASE COMPLEX | epigenetics | FINGER PROTEIN-1 | EMBRYONIC STEM-CELLS | MIXED-LINEAGE-LEUKEMIA | GENOME-WIDE ANALYSIS | POSTNATAL-DEVELOPMENT | HISTONE H3 ACETYLATION | Amino Acid Sequence | Chromatin - metabolism | DNA-Binding Proteins - physiology | Humans | Models, Molecular | Molecular Sequence Data | DNA Methylation - genetics | Protein Structure, Tertiary - genetics | DNA - metabolism | CpG Islands - physiology | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | CpG Islands - genetics | Zinc Fingers - genetics | DNA Methylation - physiology | Protein Binding - physiology | MBD, methyl-CpG-binding domain | PRC, polycomb group repressive complex | IDAX, inhibition of the Dvl and axin complex protein | ESC, embryonic stem cell | RING, really interesting new gene | CFP1, CxxC finger protein 1 | JmjC, Jumonji C | PHD, plant homeodomain | Biochemical Society Annual Symposium No. 80 | 5mC, 5-methylcytosine | CGBP, CpG-binding protein | 5hmC, 5-hydroxymethylcytosine | DNMT1, DNA methyltransferase 1 | FBXL19, F-box and leucine-rich repeat protein 19 | RFTS, replication foci-targeting sequence | WDR, WD40 repeat | DPY-30, dosage compensation protein 30 | AF9, ALL1–fused gene from chromosome 9 protein | ChIP-seq, chromatin immunoprecipitation sequencing | HDAC, histone deacetylase | YY1, Yin and Yang 1 | RbBP5, retinoblastoma-binding protein 5 | ZF-CxxC, zinc finger-CxxC | BAH, bromo-adjacent homology | ASH2L, absent, small or homeotic 2-like | SETD1, SET domain 1 | TET, ten-eleven translocation | SEC, super-elongation complex | MLL, mixed lineage leukaemia protein | CGI, CpG island | ENL, eleven-nineteen leukaemia | shRNA, short hairpin RNA | KDM, lysine demethylase | RNAPII, RNA polymerase II
Journal Article
Journal Article
Developmental Cell, ISSN 1534-5807, 04/2016, Volume 37, Issue 1, pp. 47 - 57
Journal Article
Journal Article
Journal Article