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International journal of cancer, ISSN 0020-7136, 08/2008, Volume 123, Issue 3, pp. 552 - 560
Genistein is a phytoestrogen that has been reported to suppress the AKT signaling pathway in several malignancies. However, the molecular mechanism of... 
Prostate cancer | Genistein | Tumor suppressor gene | Life Sciences & Biomedicine | Oncology | Science & Technology | PTEN Phosphohydrolase - drug effects | Prostatic Neoplasms - metabolism | Deubiquitinating Enzyme CYLD | CpG Islands - drug effects | Humans | Male | NF-kappa B - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Genes, Tumor Suppressor - drug effects | Genes, p53 - drug effects | Prostatic Neoplasms - genetics | Chromatin Immunoprecipitation | Forkhead Transcription Factors - metabolism | Sirtuin 1 | Antimetabolites, Antineoplastic - pharmacology | Electrophoretic Mobility Shift Assay | Gene Expression Regulation, Neoplastic - drug effects | Chromones - pharmacology | Anticarcinogenic Agents - pharmacology | Hydroxamic Acids - pharmacology | Phytoestrogens - pharmacology | Prostatic Neoplasms - drug therapy | PTEN Phosphohydrolase - genetics | Tumor Suppressor Proteins - metabolism | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | PTEN Phosphohydrolase - metabolism | Azacitidine - analogs & derivatives | Down-Regulation - drug effects | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Histones - drug effects | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Azacitidine - pharmacology | Acetylation - drug effects | Methylation - drug effects | Genistein - pharmacology | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Histones - metabolism | Forkhead Box Protein O3 | Sirtuins - metabolism | NF-kappa B - drug effects | Index Medicus
Journal Article
Leukemia, ISSN 1476-5551, 01/2014, Volume 28, Issue 8, pp. 1657 - 1665
Journal Article
Molecular cancer, ISSN 1476-4598, 2013, Volume 12, Issue 1, pp. 9 - 9
Background: Estrogen receptor-alpha (ER alpha)-negative breast cancer is clinically aggressive and normally does not respond to conventional estrogen... 
Breast cancer | Epigenetic | Tamoxifen | ERα | Genistein | Biochemistry & Molecular Biology | Oncology | Life Sciences & Biomedicine | Science & Technology | Gene Expression - drug effects | Humans | Tamoxifen - administration & dosage | DNA (Cytosine-5-)-Methyltransferases - metabolism | Anticarcinogenic Agents - administration & dosage | Estrogen Receptor alpha - metabolism | Female | Genistein - administration & dosage | Epigenesis, Genetic - drug effects | Anticarcinogenic Agents - pharmacology | Hydroxamic Acids - pharmacology | Estradiol - pharmacology | Cell Survival - drug effects | Promoter Regions, Genetic | Antineoplastic Agents, Hormonal - pharmacology | DNA (Cytosine-5-)-Methyltransferase 1 | Antineoplastic Agents, Hormonal - administration & dosage | Azacitidine - analogs & derivatives | Mice, Transgenic | Breast Neoplasms - drug therapy | Breast Neoplasms - prevention & control | Drug Synergism | Xenograft Model Antitumor Assays | Azacitidine - pharmacology | Animals | Estrogen Receptor alpha - genetics | Tumor Burden - drug effects | Breast Neoplasms - pathology | Mice, Nude | Genistein - pharmacology | Tamoxifen - pharmacology | Cell Line, Tumor | Histone Deacetylase Inhibitors - pharmacology | Cell Proliferation - drug effects | Mice | Histones - metabolism | Proliferating Cell Nuclear Antigen - metabolism | Drug Resistance, Neoplasm - drug effects | Histone Deacetylase 1 - metabolism | Index Medicus
Journal Article
Journal Article
BMC pharmacology & toxicology, ISSN 2050-6511, 06/2013, Volume 14, Issue 1, pp. 32 - 32
Background: Dormant cells are characterised by low RNA synthesis. In contrast, cancer cells can be addicted to high RNA synthesis, including synthesis of... 
Dormancy | Leukemia | RNA polymerase II inhibitors | Pharmacology & Pharmacy | Toxicology | Life Sciences & Biomedicine | Science & Technology | Cytarabine - pharmacology | TOR Serine-Threonine Kinases - metabolism | Adenine Nucleotides - pharmacology | Apoptosis - drug effects | Humans | Leukemia, Myeloid - genetics | Daunorubicin - pharmacology | RNA Polymerase II - metabolism | RNA, Neoplasm - metabolism | Heterocyclic Compounds, 4 or More Rings - pharmacology | Dose-Response Relationship, Drug | Leukemia, Myeloid - pathology | TOR Serine-Threonine Kinases - antagonists & inhibitors | Piperidines - pharmacology | Antineoplastic Agents - pharmacology | Flavonoids - pharmacology | Cell Survival - drug effects | Acute Disease | RNA Polymerase II - antagonists & inhibitors | Purines - pharmacology | Enzyme Inhibitors - pharmacology | Etoposide - pharmacology | Arabinonucleosides - pharmacology | Sirolimus - pharmacology | Azacitidine - pharmacology | Leukemia, Myeloid - metabolism | Cell Line, Tumor | RNA, Neoplasm - genetics | Anthracyclines | Synthesis | RNA | Heterocyclic compounds | Analysis | Physiological aspects | Etoposide | Apoptosis | DNA | Nucleosides | TOR protein | Enrichment | Flow cytometry | Cell culture | Azacytidine | Phosphorylation | Transcription | DNA damage | Kinases | Experiments | Cancer therapies | DNA-directed RNA polymerase | Dissolved organic carbon | Daunorubicin | Bone marrow | Roscovitine | Chemical synthesis | Damage | Gating | Deoxyribonucleic acid--DNA | CD34 antigen | Gene expression | Metabolism | Ribonucleic acid--RNA | Patients | Polymerase | Irinotecan | Flavopiridol | Inhibitors | Uridine | RNA polymerase II | Nucleoside analogs | Pharmaceuticals | Cancer | Index Medicus
Journal Article
Haematologica, ISSN 0390-6078, 05/2009, Volume 94, Issue 5, pp. 638 - 646
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 12/2014, Volume 111, Issue 50, pp. E5401 - E5410
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 08/2006, Volume 24, Issue 23, pp. 3771 - 3779
Journal Article