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Cochrane Database of Systematic Reviews, ISSN 1469-493X, 10/2016, Volume 2020, Issue 3, p. CD000545
Background The results from controlled clinical trials investigating the efficacy of azathioprine and 6‐mercaptopurine for the treatment of active Crohn's... 
Mesalamine | Immunosuppressive Agents | Glucocorticoids | Gastroenterology & hepatology | Azathioprine or 6‐mercaptopurine therapy | Crohn Disease | Induction Chemotherapy | Prednisone | Withholding Treatment | Antimetabolites | Randomized Controlled Trials as Topic | Crohn's disease: induction of remission | Inflammatory bowel disease | CROHN'S DISEASE ‐ INDUCTION OF REMISSION | Infliximab | Sulfasalazine | Azathioprine | Medicine General & Introductory Medical Sciences | Mercaptopurine | LONG-TERM | CLINICAL-PHARMACOLOGY | Induction Chemotherapy [methods] | Humans | 6-Mercaptopurine [adverse effects; therapeutic use] | RANDOMIZED-TRIAL | EARLY COMBINED IMMUNOSUPPRESSION | Immunosuppressive Agents [adverse effects; therapeutic use] | INFLIXIMAB PLUS AZATHIOPRINE | MEDICINE, GENERAL & INTERNAL | INFLAMMATORY-BOWEL-DISEASE | THERAPY | Crohn Disease [drug therapy] | DOUBLE-BLIND TRIAL | TERM-FOLLOW-UP | Azathioprine [adverse effects; therapeutic use] | MYCOPHENOLATE-MOFETIL | Sulfasalazine - therapeutic use | Azathioprine - therapeutic use | Glucocorticoids - administration & dosage | Prednisone - administration & dosage | Immunosuppressive Agents - therapeutic use | Induction Chemotherapy - methods | Mercaptopurine - adverse effects | Antimetabolites - therapeutic use | Infliximab - therapeutic use | Antimetabolites - adverse effects | Mercaptopurine - therapeutic use | Crohn Disease - drug therapy | Mesalamine - therapeutic use | Adult | Immunosuppressive Agents - adverse effects | Induction Chemotherapy - statistics & numerical data | Azathioprine - adverse effects
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 1532-6535, 2011, Volume 89, Issue 3, pp. 387 - 391
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2010, Volume 362, Issue 15, pp. 1383 - 1395
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2011, Volume 365, Issue 20, pp. 1886 - 1895
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 12/2010, Volume 69, Issue 12, pp. 2083 - 2089
Journal Article
by Coenen, Marieke J.H and de Jong, Dirk J and van Marrewijk, Corine J and Derijks, Luc J.J and Vermeulen, Sita H and Wong, Dennis R and Klungel, Olaf H and Verbeek, Andre L.M and Hooymans, Piet M and Peters, Wilbert H.M and te Morsche, Rene H.M and Newman, William G and Scheffer, Hans and Guchelaar, Henk-Jan and Franke, Barbara and Masclee, A.A.M and Pierik, M and Mares, W and Hameeteman, W and Wahab, P.J and Seinen, H and Rijk, M.C.M and Harkema, I.M and de Bièvre, M and Oostenbrug, L and Bakker, C.M and Aquarius, M and van Deursen, C and van Nunen, A.B and Goedhard, J.G and Hamacher, M and Gisbertz, I.A.M and Brenninkmeijer, B.J and Tan, A.C.I.T.L and Aparicio-Pagés, M.N and Witteman, E.M and van Tuyl, S.A.C and Breumelhof, R and Stronkhorst, A and Gilissen, L.P.L and Schoon, E.J and Tjhie-Wensing, J.W.M and Temmerman, A and Nicolaï, J.J and van Bergeijk, J.D and Bac, D.J and Witteman, B.J.M and Mahmmod, N and Uil, J.J and Akol, H and Ouwendijk, R.J.T and van Munster, I.P and Pennings, M and De Schryver, A.M.P and van Ditzhuijsen, T.J.M and Scheffer, R.C.H and Römkens, T.E.H and Schipper, D.L and Bus, P.J and Straathof, J.W.A and Verhulst, M.L and Boekema, P.J and Kamphuis, J.T and van Wijk, H.J and Salemans, J.M.J.L and Vermeijden, J.R and van der Werf, S.D.J and Verburg, R.J and Spoelstra, P and de Vree, J.M.L and van der Linde, K and Jebbink, H.J.A and Jansen, M and Holwerda, H and van Bentem, N and Kolkman, J.J and Russel, M.G.V.M and van Olffen, G.H and Kerbert-Dreteler, M.J and Bargeman, M and Götz, J.M and Schröder, R and Jansen, J.M and Bos, L.P and Engels, L.G.J.B and Romberg-Camps, M.J.L and Keulen, E.T.P and van Esch, A.A.J and Drenth, J.P.H and van Kouwen, M.C.A and Wanten, G.J.A and Bisseling, T.J and van Vugt, M.W.J and van de Meeberg, P.C and van den Hazel, S.J and Stuifbergen, W.N.H.M and Grubben, M.J.A.L and de Wit, U and Dodemont, G.A.H and Eichhorn, R.F and ... and TOPIC Recruitment Team
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2015, Volume 149, Issue 4, pp. 907 - 917.e7
Background & Aims More than 20% of patients with inflammatory bowel disease (IBD) discontinue thiopurine therapy because of severe adverse drug reactions... 
Gastroenterology and Hepatology | Side Effect | Pharmacogenetic | Leukocyte | Adverse Event | CROHNS-DISEASE | RANDOMIZED-TRIAL | TOXICITY | AMINOSALICYLATES | MYELOSUPPRESSION | INOSINE TRIPHOSPHATE PYROPHOSPHATASE | S-METHYLTRANSFERASE ACTIVITY | AZATHIOPRINE THERAPY | GENES | PHARMACOGENETICS | GASTROENTEROLOGY & HEPATOLOGY | Crohn Disease - genetics | Predictive Value of Tests | Azathioprine - administration & dosage | Colitis, Ulcerative - enzymology | Genetic Testing | Prospective Studies | Humans | Methyltransferases - metabolism | Middle Aged | Colitis, Ulcerative - genetics | Gastrointestinal Agents - administration & dosage | Methyltransferases - genetics | Male | Anti-Inflammatory Agents - metabolism | Genetic Variation | Young Adult | Drug Dosage Calculations | Netherlands | Anti-Inflammatory Agents - adverse effects | Crohn Disease - diagnosis | Leukopenia - chemically induced | Mercaptopurine - metabolism | Adult | Anti-Inflammatory Agents - administration & dosage | Female | Colitis, Ulcerative - drug therapy | Leukopenia - prevention & control | Crohn Disease - enzymology | Pharmacogenetics | Azathioprine - metabolism | Risk Factors | Mercaptopurine - administration & dosage | Mercaptopurine - adverse effects | Treatment Outcome | Thrombocytopenia - chemically induced | Homozygote | Phenotype | Colitis, Ulcerative - diagnosis | Crohn Disease - drug therapy | Thrombocytopenia - prevention & control | Heterozygote | Gastrointestinal Agents - adverse effects | Azathioprine - adverse effects | Gastrointestinal Agents - metabolism | Enzymes | Care and treatment | Metabolites | Analysis | Gastrointestinal diseases | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Nature genetics, ISSN 1546-1718, 2014, Volume 46, Issue 10, pp. 1131 - 1134
Journal Article