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Journal Article
Psychopharmacology, ISSN 0033-3158, 5/2014, Volume 231, Issue 9, pp. 1975 - 1985
Neuronal nicotinic acetylcholine receptors (nAChRs) play a modulatory role in cognition, and zebrafish provide a preclinical model to study learning and... 
Neurosciences | α-Conotoxin | Scopolamine | Neuronal nicotinic receptors | Zebrafish | Cholinergic system | Methyllycaconitine | Mecamylamine | Biomedicine | Dihydro-β-erythroidine | Pharmacology/Toxicology | T-maze | Psychiatry | Spatial memory | Dihydro-beta-erythroidine | DANIO-RERIO | TASK | CHOLINERGIC CHANNEL ACTIVATOR | PSYCHIATRY | BEHAVIOR | INVOLVEMENT | Spatialmemory | SYNAPTIC PLASTICITY | NEUROSCIENCES | COGNITIVE FUNCTION | SELECTIVE STIMULATION | PARTIAL AGONIST | PHARMACOLOGY & PHARMACY | alpha-Conotoxin | WORKING-MEMORY | Memory - drug effects | Cholinergic Agents - pharmacology | Dihydro-beta-Erythroidine - pharmacology | Nicotinic Antagonists - pharmacology | Nicotine - pharmacology | Dose-Response Relationship, Drug | Scopolamine Hydrobromide - pharmacology | Muscarinic Antagonists - pharmacology | Mecamylamine - pharmacology | Neurons - physiology | Swimming | Neurons - drug effects | Nicotinic Agonists - pharmacology | Azocines - chemistry | Receptors, Nicotinic - metabolism | Alkaloids - pharmacology | Maze Learning - physiology | Zebrafish Proteins - metabolism | Quinolizines - pharmacology | Aconitine - analogs & derivatives | Aconitine - pharmacology | Maze Learning - drug effects | Conotoxins - pharmacology | Animals | Nicotinic Antagonists - chemistry | Zebrafish - physiology | Azocines - pharmacology | Alkaloids - chemistry | Quinolizines - chemistry | Memory - physiology | Learning | Receptors | Memory | Zebra fish | Physiological aspects | Genetic aspects | Acetylcholine | Research | Fish | Psychopharmacology | Animal memory | Index Medicus
Journal Article
Psychopharmacology, ISSN 0033-3158, 7/2013, Volume 228, Issue 2, pp. 321 - 333
Receptor mechanisms underlying the behavioral effects of clinically used nicotinic acetylcholine receptor agonists have not been fully established.Drug... 
Drug discrimination | Neurosciences | Agonist | Varenicline | Cytisine | Efficacy | Mecamylamine | Biomedicine | Mouse | Antagonist | Dihydro-β-erythroidine | Pharmacology/Toxicology | Psychiatry | Nicotine | Dihydro-beta-erythroidine | PSYCHIATRY | PHARMACOLOGICAL CHARACTERIZATION | RATS | RECEPTOR PARTIAL AGONIST | NEUROSCIENCES | ACETYLCHOLINE-RECEPTORS | MU OPIOIDS | PHARMACOLOGY & PHARMACY | DISCRIMINATIVE STIMULUS PROPERTIES | ALPHA-4-BETA-2 | Nicotine - administration & dosage | Dihydro-beta-Erythroidine - pharmacology | Male | Nicotine - pharmacology | Dose-Response Relationship, Drug | Quinoxalines - pharmacology | Discrimination Learning - drug effects | Tobacco Use Cessation Products | Mecamylamine - pharmacology | Nicotinic Agonists - pharmacology | Quinolizines - administration & dosage | Receptors, Nicotinic - drug effects | Receptors, Nicotinic - metabolism | Alkaloids - pharmacology | Morphine - pharmacology | Quinoxalines - administration & dosage | Mice, Inbred C57BL | Quinolizines - pharmacology | Benzazepines - pharmacology | Smoking Cessation - methods | Nicotinic Agonists - administration & dosage | Animals | Alkaloids - administration & dosage | Azocines - pharmacology | Benzazepines - administration & dosage | Mice | Azocines - administration & dosage | Midazolam - pharmacology | Smoking cessation programs | Dosage and administration | Health aspects | Smoking cessation | Pharmacology | Rodents | Index Medicus | dihydro-β-erythroidine | mecamylamine | varenicline | mouse | nicotine | drug discrimination | agonist | antagonist | cytisine | efficacy
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 01/1997, Volume 17, Issue 2, pp. 576 - 585
Presynaptic nicotinic acetylcholine receptors (nAChRs) are present in many regions of the brain and potentially serve as targets for the pharmacological action... 
GABA | calcium | facilitation | thalamus (sensory nuclei) | nicotinic acetylcholine receptors | presynaptic | ADRENAL CHROMAFFIN CELLS | INTERPEDUNCULAR NUCLEUS | FROG NEUROMUSCULAR-JUNCTION | OPTIC-NERVE TERMINALS | RAT CENTRAL NEURONS | NEUROSCIENCES | LATERAL GENICULATE-NUCLEUS | ACETYLCHOLINE-RECEPTORS | SUBUNIT MESSENGER-RNAS | CHOLINERGIC RECEPTORS | EXCITATORY SYNAPTIC TRANSMISSION | Thalamic Nuclei - metabolism | Dihydro-beta-Erythroidine - pharmacology | Lobeline - pharmacology | Nicotinic Antagonists - pharmacology | Pyridazines - pharmacology | Cations, Divalent - pharmacology | Nicotine - pharmacology | Quinolizines | Calcium Channels - physiology | Calcium - physiology | Receptors, Nicotinic - chemistry | Receptors, GABA-A - drug effects | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Receptors, Nicotinic - deficiency | Dimethylphenylpiperazinium Iodide - pharmacology | Ion Transport | gamma-Aminobutyric Acid - secretion | Tetrodotoxin - pharmacology | Action Potentials - drug effects | Nicotinic Agonists - pharmacology | Microcystins | Alkaloids - pharmacology | Mice, Inbred C57BL | Atropine - pharmacology | Aconitine - analogs & derivatives | Marine Toxins - pharmacology | Aconitine - pharmacology | Calcium Channel Blockers - pharmacology | Potassium - pharmacology | Neurons, Afferent - physiology | GABA Antagonists - pharmacology | Mice, Knockout | Carbachol - pharmacology | Arousal - physiology | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Patch-Clamp Techniques | Animals | Azocines | Receptors, Nicotinic - physiology | Bacterial Toxins - pharmacology | Thalamic Nuclei - secretion | Mice | Pyridines - pharmacology | Receptors, Nicotinic - genetics | Index Medicus
Journal Article
The Journal of Physiology, ISSN 0022-3751, 01/2009, Volume 587, Issue 2, pp. 345 - 361
Journal Article
Journal Article
Journal Article
Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 35, pp. 37410 - 37425
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2017, Volume 12, Issue 6, pp. e0178606 - e0178606
Glucocorticoids (GCs) and topoisomerase II inhibitors are used to treat acute lymphoblastic leukaemia (ALL) as they induce death in lymphoid cells through the... 
CANCER-CELLS | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | ACUTE LYMPHOBLASTIC-LEUKEMIA | HEMATOLOGICAL MALIGNANCIES | GLUCOCORTICOID-INDUCED APOPTOSIS | GENE-EXPRESSION | INDUCE APOPTOSIS | LYMPHOID-CELLS | RECEPTOR PHOSPHORYLATION | MOLECULAR-MECHANISMS | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Receptors, Glucocorticoid - antagonists & inhibitors | Apoptosis - drug effects | Inhibitor of Apoptosis Proteins - genetics | Humans | Caspase 3 - metabolism | Caspase 8 - metabolism | Gene Expression Regulation, Neoplastic | Transcriptome | Ubiquitin-Protein Ligases - antagonists & inhibitors | Culture Media, Conditioned - pharmacology | Baculoviral IAP Repeat-Containing 3 Protein | Receptors, Glucocorticoid - metabolism | Bone Marrow Cells - secretion | Necrosis - pathology | Caspase 8 - genetics | Dexamethasone - pharmacology | Tumor Microenvironment - genetics | Inhibitor of Apoptosis Proteins - antagonists & inhibitors | Caspase 3 - genetics | Antineoplastic Agents - pharmacology | Inhibitor of Apoptosis Proteins - metabolism | Phosphorylation - drug effects | Tumor Microenvironment - drug effects | Cell Line | Signal Transduction | Bone Marrow Cells - pathology | Ubiquitin-Protein Ligases - metabolism | Etoposide - pharmacology | Necrosis - metabolism | Topoisomerase II Inhibitors - pharmacology | Necrosis - chemically induced | Drug Resistance, Neoplasm - genetics | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | K562 Cells | Receptors, Glucocorticoid - genetics | Beclin-1 - genetics | Cell Line, Tumor | Glucocorticoids - pharmacology | Azocines - pharmacology | Benzhydryl Compounds - pharmacology | Necrosis - genetics | Beclin-1 - metabolism | Ubiquitin-Protein Ligases - genetics | Cell proliferation | Leukemia | Etoposide | Dosage and administration | Research | Tumor proteins | Health aspects | Apoptosis | Flow cytometry | Correlation | Phosphorylation | Glucocorticoids | Genomics | p53 Protein | Chemoresistance | Biology | Kinases | Assaying | Autophagy | Cancer therapies | Molecular weight | Proteins | Control | Pathways | Rodents | Bone marrow | Life sciences | Conditioning | Medical research | DNA topoisomerase (ATP-hydrolysing) | Lymphoid cells | Dexamethasone | Acute lymphatic leukemia | Cell survival | Incubation | Mortality | Markers | Media | Caspase | Principal components analysis | Gene expression | Survival | Promoters | Medicine | Caspase-8 | Chemotherapy | Inhibitors | Cell death | Media (differential) | Determinants | Phagocytosis | Index Medicus
Journal Article