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Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 11/2013, Volume 56, Issue 22, pp. 9089 - 9099
A novel series of compounds obtained by fusing the cholinesterase inhibitor donepezil and the antioxidant ebselen were designed as multi-target-directed... 
MAMMALIAN THIOREDOXIN | CHEMISTRY, MEDICINAL | ACETYLCHOLINESTERASE | PEROXYNITRITE | DIPHENYL DISELENIDE | AMYLOID-BETA-PEPTIDES | ORGANOSELENIUM COMPOUNDS | HUMAN HEALTH | NITRIC-OXIDE | THIOREDOXIN REDUCTASE | BIOLOGICAL ASSESSMENT | Cholinesterase Inhibitors - toxicity | Organoselenium Compounds - chemical synthesis | Humans | Azoles - metabolism | Cholinesterase Inhibitors - chemical synthesis | Toxicity Tests, Acute | Molecular Targeted Therapy | Organoselenium Compounds - pharmacology | Cholinesterase Inhibitors - metabolism | Piperidines - pharmacology | Thioredoxin-Disulfide Reductase - metabolism | Butyrylcholinesterase - metabolism | Azoles - toxicity | Glutathione Peroxidase - metabolism | Piperidines - toxicity | Chemistry Techniques, Synthetic | Protein Structure, Secondary | Piperidines - metabolism | Indans - metabolism | Alzheimer Disease - drug therapy | Electrophorus | Acetylcholinesterase - chemistry | Azoles - chemical synthesis | Azoles - pharmacology | Piperidines - chemical synthesis | Organoselenium Compounds - toxicity | Peptide Fragments - chemistry | Animals | Cholinesterase Inhibitors - pharmacology | Peroxynitrous Acid - metabolism | Indans - toxicity | Indans - chemical synthesis | Ligands | Mice | Molecular Docking Simulation | Amyloid beta-Peptides - chemistry | Kinetics | Acetylcholinesterase - metabolism | Organoselenium Compounds - metabolism | Protein Multimerization - drug effects | Indans - pharmacology | Index Medicus
Journal Article
Journal Article
Chemosphere, ISSN 0045-6535, 02/2020, Volume 241, p. 124993
Azoles are emerging contaminants that are resistant to biodegradation during wastewater treatment. Their presence has been widely reported in wastewater... 
Microbial inhibition | Azoles | Biological | Toxicity
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 11/2013, Volume 135, Issue 44, pp. 16384 - 16387
Journal Article
Molecular Biology Reports, ISSN 0301-4851, 8/2014, Volume 41, Issue 8, pp. 4865 - 4879
Journal Article
Expert Review of Anti-Infective Therapy, ISSN 1478-7210, 06/2015, Volume 13, Issue 6, pp. 787 - 798
Journal Article
Journal Article