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Journal of Clinical Oncology, ISSN 0732-183X, 09/2015, Volume 33, Issue 27, pp. 2938 - 2948
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2017, Volume 376, Issue 9, pp. 836 - 847
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 09/2014, Volume 371, Issue 11, pp. 1005 - 1015
About 25% of young adults with ALL have Ph-like genotypes, which are associated with poor outcomes with conventional treatment. In this gene-expression study,... 
MEDICINE, GENERAL & INTERNAL | MODELS | B-CELL PRECURSOR | INHIBITOR THERAPY | IMATINIB | PEDIATRIC ACUTE LEUKEMIAS | GENE FUSION | EXPRESSION | ETV6-NTRK3 FUSION TRANSCRIPTS | CRLF2 | DELETION | Oligonucleotide Array Sequence Analysis | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Humans | Child, Preschool | Infant | Male | Young Adult | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Heterografts | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - mortality | Adult | Female | DNA, Neoplasm - analysis | Receptors, Cytokine - metabolism | Child | Philadelphia Chromosome | Receptors, Cytokine - genetics | Signal Transduction - genetics | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Animals | Protein Kinase Inhibitors - therapeutic use | Adolescent | Survival Analysis | Mice | Polymorphism, Single Nucleotide | Genome, Human | Protein-Tyrosine Kinases - antagonists & inhibitors | Development and progression | Care and treatment | Genetic aspects | Research | Lymphocytic leukemia | Tyrosine metabolism | Cell proliferation | Adolescence | Tyk2 protein | Leukemia | Genes | Clinical trials | Oncology | Genomes | Kinases | Cell activation | Janus kinase 2 | Xenografts | Teenagers | Children | Protein-tyrosine kinase | Age | Tyrosine | Young adults | Genomic analysis | Acute lymphatic leukemia | Stat5 protein | Lymphatic leukemia | Gene expression | Philadelphia chromosome | Interleukin 7 receptors | Thymic stromal lymphopoietin | Lymphocytes B | Cell lines
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 09/2016, Volume 375, Issue 11, pp. 1044 - 1053
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 02/2018, Volume 378, Issue 5, pp. 449 - 459
Journal Article
Science Translational Medicine, ISSN 1946-6234, 02/2014, Volume 6, Issue 224, pp. 224ra25 - 224ra25
We report on 16 patients with relapsed or refractory B cell acute lymphoblastic leukemia (B-ALL) that we treated with autologous T cells expressing the 19-28z... 
Young Adult | Humans | Immunotherapy | Middle Aged | Adolescent | Adult | Cell Transplantation | Female | Male | T-Lymphocytes - immunology | Leukemia, B-Cell - therapy | MEDICINE, RESEARCH & EXPERIMENTAL | CELL BIOLOGY | Index Medicus
Journal Article
Nature Immunology, ISSN 1529-2908, 07/2015, Volume 16, Issue 7, pp. 766 - 774
Childhood acute lymphoblastic leukemia (ALL) can often be traced to a pre-leukemic clone carrying a prenatal genetic lesion. Postnatally acquired mutations... 
B-CELL DEVELOPMENT | RECOMBINATION | CYTIDINE DEAMINASE AID | ACTIVATION | GENE | CHROMOSOME TRANSLOCATIONS | IMMUNOLOGY | CLASS SWITCH | EXPRESSION | MONOZYGOTIC TWINS | DAY-CARE | Cytidine Deaminase - immunology | Precursor Cell Lymphoblastic Leukemia-Lymphoma - immunology | Homeodomain Proteins - metabolism | Humans | Precursor Cells, B-Lymphoid - metabolism | Child, Preschool | Immunoblotting | Infant | Male | Precursor Cells, B-Lymphoid - immunology | Homeodomain Proteins - immunology | Clonal Evolution - genetics | DNA-Binding Proteins - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Antibody Diversity - genetics | Flow Cytometry | Antibody Diversity - immunology | Female | Tumor Cells, Cultured | Child | B-Lymphocytes - metabolism | DNA-Binding Proteins - immunology | Cytidine Deaminase - genetics | Mice, Transgenic | DNA-Binding Proteins - genetics | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Homeodomain Proteins - genetics | Mice, Knockout | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Animals | B-Lymphocytes - immunology | Cytidine Deaminase - metabolism | Adolescent | Mice, Inbred NOD | Clonal Evolution - immunology | Microscopy, Fluorescence | Gene mutations | Genetic susceptibility | Oncology, Experimental | Genetic research | Development and progression | Genetic aspects | Acute lymphocytic leukemia | Research | Identification and classification | Health aspects | Cancer
Journal Article
Journal Article