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Journal Article
Blood, ISSN 0006-4971, 2016, Volume 127, Issue 14, pp. 1780 - 1789
Journal Article
Seminars in Immunology, ISSN 1044-5323, 2006, Volume 18, Issue 5, pp. 263 - 275
BAFF, APRIL and their receptors play important immunological roles, especially in the B cell arm of the immune system. A number of splice isoforms have been... 
Signaling | BAFF | B cells | Structure | Splice variants | MATURATION ANTIGEN | signaling | PROTEIN-KINASE | splice variants | COMMON VARIABLE IMMUNODEFICIENCY | LYMPHOCYTE STIMULATOR | T-CELL | IMMUNOLOGY | structure | TNF FAMILY | CELL-ACTIVATING FACTOR | NECROSIS-FACTOR FAMILY | NF-KAPPA-B | AUTOIMMUNE-DISEASE | B-Cell Activating Factor - physiology | Alternative Splicing | Humans | Substrate Specificity | Structure-Activity Relationship | Lymphocyte Subsets - immunology | Immunoglobulin Class Switching - physiology | Protein Kinase C-delta - antagonists & inhibitors | B-Cell Activating Factor - immunology | Tumor Necrosis Factor Ligand Superfamily Member 13 - chemistry | B-Cell Activation Factor Receptor - genetics | B-Cell Activation Factor Receptor - immunology | B-Cell Activation Factor Receptor - chemistry | Tumor Necrosis Factor Ligand Superfamily Member 13 - immunology | B-Lymphocytes - cytology | Transmembrane Activator and CAML Interactor Protein - chemistry | Signal Transduction | B-Cell Maturation Antigen - physiology | Lymphocyte Activation | B-Cell Activating Factor - chemistry | Tumor Necrosis Factor Ligand Superfamily Member 13 - physiology | Models, Molecular | B-Cell Activation Factor Receptor - physiology | Transmembrane Activator and CAML Interactor Protein - physiology | Protein Interaction Mapping | Transmembrane Activator and CAML Interactor Protein - genetics | Animals | B-Lymphocytes - immunology | B-Cell Activating Factor - genetics | NF-kappa B - physiology | Protein Conformation | Tumor Necrosis Factor Ligand Superfamily Member 13 - genetics | Mice | NF-kappa B p50 Subunit - physiology | Apoptosis - physiology | Transmembrane Activator and CAML Interactor Protein - immunology | Antigen Presentation - physiology
Journal Article
Blood, ISSN 0006-4971, 06/2011, Volume 117, Issue 23, pp. 6287 - 6296
B-cell receptor (BCR) signaling is aberrantly activated in chronic lymphocytic leukemia (CLL). Bruton tyrosine kinase (BTK) is essential to BCR signaling and... 
B-CELLS | SURVIVAL | APOPTOSIS | ACTIVATION | FLUDARABINE PLUS CYCLOPHOSPHAMIDE | RITUXIMAB | LYMPHOMA | PROLIFERATION | INHIBITOR | HEMATOLOGY | EXPRESSION | T-Lymphocytes - enzymology | Apoptosis - drug effects | Humans | Tumor Necrosis Factor-alpha - genetics | Cell Survival - genetics | Apoptosis - genetics | Male | NF-kappa B - metabolism | Neoplasm Proteins - antagonists & inhibitors | Receptors, Antigen, B-Cell - metabolism | Mitogen-Activated Protein Kinase 1 - genetics | Neoplasm Proteins - genetics | Interleukin-6 - metabolism | Cell Survival - drug effects | Drug Screening Assays, Antitumor - methods | Interleukin-6 - genetics | Mitogen-Activated Protein Kinase 3 - genetics | Gene Expression Regulation, Leukemic - drug effects | Pyrimidines - pharmacology | Leukemia, Lymphocytic, Chronic, B-Cell - enzymology | B-Cell Activating Factor - metabolism | CD40 Ligand - genetics | Mitogen-Activated Protein Kinase 3 - metabolism | Gene Expression Regulation, Enzymologic - genetics | Cell Line, Tumor | Receptors, Antigen, B-Cell - genetics | Mice | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Mitogen-Activated Protein Kinase 1 - metabolism | Protein-Tyrosine Kinases - antagonists & inhibitors | Tumor Necrosis Factor-alpha - metabolism | Gene Expression Regulation, Enzymologic - drug effects | Phosphatidylinositol 3-Kinases - metabolism | Gene Expression Regulation, Leukemic - genetics | Protein-Tyrosine Kinases - genetics | CD40 Ligand - metabolism | MAP Kinase Signaling System - genetics | Female | Interleukin-4 - genetics | Protein-Tyrosine Kinases - biosynthesis | Pyrazoles - pharmacology | B-Lymphocytes - enzymology | Neoplasm Proteins - biosynthesis | Interleukin-4 - metabolism | Phosphatidylinositol 3-Kinases - genetics | Animals | MAP Kinase Signaling System - drug effects | NF-kappa B - genetics | B-Cell Activating Factor - genetics | Cell Proliferation - drug effects | Lymphoid Neoplasia
Journal Article
by Steri, Maristella and Orrù, Valeria and Idda, M. Laura and Pitzalis, Maristella and Pala, Mauro and Zara, Ilenia and Sidore, Carlo and Faà, Valeria and Floris, Matteo and Deiana, Manila and Asunis, Isadora and Porcu, Eleonora and Mulas, Antonella and Piras, Maria G and Lobina, Monia and Lai, Sandra and Marongiu, Michele and Marongiu, Mara and Serra, Valentina and Sole, Gabriella and Busonero, Fabio and Maschio, Andrea and Cusano, Roberto and Cuccuru, Gianmauro and Deidda, Francesca and Poddie, Fausto and Farina, Gabriele and Dei, Mariano and Virdis, Francesca and Olla, Stefania and Satta, Maria A and Pani, Mario and Pani, Antonello and Delitala, Alessandro and Cocco, Eleonora and Frau, Jessica and Coghe, Giancarlo and Lorefice, Lorena and Fenu, Giuseppe and Ferrigno, Paola and Ban, Maria and Barizzone, Nadia and Leone, Maurizio and Guerini, Franca R and Piga, Matteo and Firinu, Davide and Kockum, Ingrid and Lima Bomfim, Izaura and Olsson, Tomas and Alfredsson, Lars and Suarez, Ana and Carreira, Patricia E and Castillo-Palma, Maria J and Marcus, Joseph H and Congia, Mauro and Angius, Andrea and Melis, Maurizio and Gonzalez, Antonio and Alarcón Riquelme, Marta E and da Silva, Berta M and Marchini, Maurizio and Danieli, Maria G and Del Giacco, Stefano and Mathieu, Alessandro and Montgomery, Stephen B and Rosati, Giulio and Hillert, Jan and Sawcer, Stephen and D’Alfonso, Sandra and Todd, John A and Novembre, John and Abecasis, Gonçalo R and Whalen, Michael B and Marrosu, Maria G and Meloni, Alessandra and Sanna, Serena and Gorospe, Myriam and Schlessinger, David and Fiorillo, Edoardo and Zoledziewska, Magdalena and Cucca, Francesco
The New England Journal of Medicine, ISSN 0028-4793, 04/2017, Volume 376, Issue 17, pp. 1615 - 1626
Journal Article
Immunological Reviews, ISSN 0105-2896, 11/2011, Volume 244, Issue 1, pp. 115 - 133
Members of the tumor necrosis factor receptor superfamily (TNFRSF) participate prominently in B‐cell maturation and function. In particular, B‐cell activating... 
BAFF | B cell | CD40 | BCMA | NF‐κB | TACI | NF-κB | FORKHEAD TRANSCRIPTION FACTOR | SYSTEMIC-LUPUS-ERYTHEMATOSUS | HUMORAL IMMUNE-RESPONSES | COMMON VARIABLE IMMUNODEFICIENCY | IMMUNOLOGY | KINASE-C-DELTA | GERMINAL CENTER FORMATION | NF-?B | ACTIVATING FACTOR-RECEPTOR | NON-HODGKIN-LYMPHOMA | X-LINKED IMMUNODEFICIENCY | NF-KAPPA-B | Cell Proliferation | Humans | NF-kappa B - immunology | NF-kappa B - metabolism | Transmembrane Activator and CAML Interactor Protein - metabolism | Signal Transduction - immunology | CD40 Antigens - metabolism | B-Cell Activating Factor - immunology | B-Lymphocyte Subsets - immunology | CD40 Antigens - genetics | B-Cell Activation Factor Receptor - genetics | B-Lymphocytes - metabolism | B-Cell Activation Factor Receptor - immunology | B-Cell Maturation Antigen - immunology | Tumor Necrosis Factor Ligand Superfamily Member 13 - immunology | Gene Expression | Mice, Transgenic | Cell Survival - immunology | Immunity, Innate | Tumor Necrosis Factor Ligand Superfamily Member 13 - metabolism | Transmembrane Activator and CAML Interactor Protein - genetics | B-Cell Activation Factor Receptor - metabolism | Animals | B-Cell Activating Factor - metabolism | B-Cell Maturation Antigen - metabolism | B-Lymphocytes - immunology | B-Lymphocyte Subsets - metabolism | NF-kappa B - genetics | B-Cell Activating Factor - genetics | Neoplasms - immunology | Autoimmune Diseases | Tumor Necrosis Factor Ligand Superfamily Member 13 - genetics | Mice | B-Cell Maturation Antigen - genetics | Transmembrane Activator and CAML Interactor Protein - immunology | CD40 Antigens - immunology | Autoimmunity | Antigens | Tumor necrosis factor | Tumors | Necrosis
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2011, Volume 121, Issue 10, pp. 3991 - 4002
Journal Article
Journal of Immunology, ISSN 0022-1767, 01/2015, Volume 194, Issue 2, pp. 542 - 552
Journal Article
Blood, ISSN 0006-4971, 2008, Volume 111, Issue 3, pp. 1004 - 1012
Journal Article