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Immunity, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 475 - 488
Follicular B cell survival requires signaling from BAFFR, a receptor for BAFF and the B cell antigen receptor (BCR). This “tonic” BCR survival signal is... 
TACI | AKT | BCMA | IMMUNOLOGY | MATURATION | ACTIVATING FACTOR | AUTOIMMUNE-DISEASE | SYK TYROSINE KINASE | MICE LACKING | FAMILY | ANTIGEN | Oligonucleotide Array Sequence Analysis | Protein-Tyrosine Kinases - metabolism | Cell Survival - genetics | Immunoblotting | Gene Expression Profiling | Intracellular Signaling Peptides and Proteins - metabolism | Receptors, Antigen, B-Cell - metabolism | Extracellular Signal-Regulated MAP Kinases - immunology | Phosphatidylinositol 3-Kinases - immunology | Phosphorylation - drug effects | B-Cell Activation Factor Receptor - genetics | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | 3-Phosphoinositide-Dependent Protein Kinases | B-Lymphocytes - metabolism | Protein-Serine-Threonine Kinases - metabolism | B-Cell Activation Factor Receptor - immunology | Cell Survival - drug effects | RNA, Untranslated | Mice, Transgenic | Mice, Knockout | B-Cell Activation Factor Receptor - metabolism | Models, Immunological | B-Lymphocytes - immunology | Signal Transduction - drug effects | Mice | CD79 Antigens - immunology | Intracellular Signaling Peptides and Proteins - immunology | Phosphatidylinositol 3-Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Protein-Tyrosine Kinases - immunology | Signal Transduction - immunology | Protein-Tyrosine Kinases - genetics | Flow Cytometry | B-Cell Activating Factor - immunology | Protein-Serine-Threonine Kinases - genetics | Cell Survival - immunology | Proteins - immunology | Receptors, Antigen, B-Cell - immunology | CD79 Antigens - metabolism | Proteins - genetics | Receptor Cross-Talk - immunology | B-Lymphocytes - drug effects | Animals | Proteins - metabolism | Tamoxifen - pharmacology | Protein-Serine-Threonine Kinases - immunology | B-Cell Activating Factor - pharmacology | Proteins | Genetic research | Cells | Bone marrow | Antigens | Kinases | Rodents | Immune system | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 2008, Volume 111, Issue 3, pp. 1004 - 1012
Journal Article
Nature Immunology, ISSN 1529-2908, 03/2007, Volume 8, Issue 3, pp. 247 - 256
T helper cells that produce interleukin 17 (IL-17) are associated with inflammation and the control of certain bacteria. We report here the essential... 
PATHWAYS | ENCEPHALOMYELITIS | EPITHELIAL-CELLS | MULTIPLE-SCLEROSIS | FAMILY-MEMBERS | RECEPTOR COMPLEX | DEFICIENT MICE | IMMUNOLOGY | EXPRESSION | T-CELLS | CUTTING EDGE | Autoimmunity | Encephalomyelitis, Autoimmune, Experimental - metabolism | Humans | Receptors, Interleukin-17 - immunology | Interleukin-17 - immunology | Encephalomyelitis, Autoimmune, Experimental - immunology | Colitis - pathology | Adoptive Transfer | Signal Transduction - immunology | CD40 Antigens - metabolism | Transfection | Adaptor Proteins, Signal Transducing - immunology | Female | Receptors, Interleukin-17 - metabolism | Colitis - immunology | B-Cell Activation Factor Receptor - immunology | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins | Gene Expression | Encephalomyelitis, Autoimmune, Experimental - pathology | Enzyme-Linked Immunosorbent Assay | Gene Expression Regulation - immunology | Inflammation - immunology | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-17 - metabolism | B-Cell Activation Factor Receptor - metabolism | Animals | Autoimmune Diseases | Colitis - metabolism | Fluorescent Antibody Technique | T-Lymphocytes - immunology | Mice | HeLa Cells | Adaptor Proteins, Signal Transducing - metabolism | CD40 Antigens - immunology | Immune response | Interleukins | Physiological aspects | Cellular signal transduction | Inflammation | Genetic aspects | Research | Binding proteins | Risk factors | Index Medicus
Journal Article
Journal of Immunology, ISSN 0022-1767, 01/2012, Volume 188, Issue 1, pp. 497 - 503
Journal Article
The EMBO Journal, ISSN 0261-4189, 04/2015, Volume 34, Issue 7, pp. 925 - 939
The development and function of B lymphocytes is regulated by numerous signaling pathways, some emanating from the B‐cell antigen receptor ( BCR ). The spleen... 
BAFF | CD | 2 | receptor | T | Syk | B‐cell antigen receptor | 19 | mb1‐Cre | ER | BAFF receptor | mb1-CreER T 2 | B-cell antigen receptor | CD19 | LYN | ACTIVATION | mb1-CreER(T2) | MARGINAL ZONE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROTEIN-TYROSINE KINASE | PHOSPHOINOSITIDE 3-KINASE | CELL BIOLOGY | RECOMBINASE ACTIVITY | IN-VIVO | DIFFERENTIATION | NF-KAPPA-B | ANTIGEN RECEPTOR | Antigens, CD - immunology | CD40 Antigens - antagonists & inhibitors | Cell Survival - genetics | Intracellular Signaling Peptides and Proteins - immunology | Antigens, CD19 - genetics | Antigens, CD - genetics | Phosphatidylinositol 3-Kinases - immunology | Protein-Tyrosine Kinases - immunology | Signal Transduction - immunology | Protein-Tyrosine Kinases - genetics | ADP-ribosyl Cyclase 1 - immunology | CD40 Antigens - genetics | Interleukin-4 - genetics | Membrane Glycoproteins - immunology | B-Cell Activation Factor Receptor - genetics | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | Antigens, CD19 - immunology | B-Cell Activation Factor Receptor - immunology | B-Lymphocytes - cytology | Interleukin-4 - antagonists & inhibitors | ADP-ribosyl Cyclase 1 - genetics | Signal Transduction - genetics | Cell Survival - immunology | Receptors, Antigen, B-Cell - immunology | Membrane Glycoproteins - genetics | Mice, Knockout | Antibodies - pharmacology | Phosphatidylinositol 3-Kinases - genetics | Interleukin-4 - immunology | Animals | B-Lymphocytes - immunology | Lipopolysaccharides - pharmacology | Receptors, Antigen, B-Cell - genetics | Mice | Oligodeoxyribonucleotides - pharmacology | CD40 Antigens - immunology | Lymphocyte receptors | T cell receptors | Kinases | Immune system | Index Medicus | mb1-CreERT2
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, pp. e60430 - e60430
Aims: Option to attenuate atherosclerosis by depleting B2 cells is currently limited to anti-CD20 antibodies which deplete all B-cell subtypes. In the present... 
B-CELLS | SURVIVAL | CYTOKINES | CELL-ACTIVATING FACTOR | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | DISEASE | CD4(+) T-CELLS | E KNOCKOUT MICE | NATURAL IGM | AGGRAVATES ATHEROSCLEROSIS | Antigens, CD - immunology | Spleen - immunology | Apolipoproteins E - deficiency | Male | Spleen - drug effects | Lymphocyte Depletion | Antigens, CD - genetics | B-Cell Activation Factor Receptor - antagonists & inhibitors | Diet, High-Fat | B-Lymphocyte Subsets - immunology | Spleen - pathology | B-Cell Activation Factor Receptor - genetics | Antibodies, Monoclonal - immunology | Hyperlipidemias - complications | B-Cell Activation Factor Receptor - immunology | Cytokines - immunology | Hyperlipidemias - immunology | B-Lymphocyte Subsets - drug effects | Atherosclerosis - pathology | Atherosclerosis - drug therapy | Atherosclerosis - immunology | B-Lymphocyte Subsets - pathology | Antibodies, Monoclonal - pharmacology | Hyperlipidemias - drug therapy | Atherosclerosis - complications | Disease Progression | Mice, Knockout | Animals | Apolipoproteins E - genetics | Apolipoproteins E - immunology | Hyperlipidemias - pathology | Mice | Cytokines - biosynthesis | Heart | Health sciences | Vascular cell adhesion molecule 1 | Laboratories | CD8 antigen | Medical services | Lipids | Cardiovascular disease | Lymphocytes T | Biology | Inflammatory diseases | High fat diet | Immunology | Lymphocytes | Apolipoprotein E | Rodents | Atherosclerosis | Interleukin 1 | Lesions | Heart diseases | Spleen | Medical research | Antigens | Immunoglobulins | CD19 antigen | Cytokines | Inflammation | Tumor necrosis factor-α | Gene expression | Apolipoproteins | Thrombosis | CD4 antigen | Medicine | Nursing | Depletion | Lymphocytes B | BLyS protein | Arteriosclerosis | γ-Interferon | Monoclonal antibodies | CD20 antigen | TNF inhibitors | Bans | Diabetes | Autoimmune diseases | Cardiovascular diseases | Index Medicus
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 12/2017, Volume 190, Issue 3, pp. 372 - 383
Serum levels of B cell‐activating factor (BAFF) rise following rituximab (RTX) therapy in patients with rheumatoid arthritis (RA). Initiation of naive B cell... 
B lymphocytes | rheumatoid arthritis | rituximab | ANTIBODIES | SYSTEMIC-LUPUS-ERYTHEMATOSUS | PRIMARY SJOGRENS-SYNDROME | DEPLETION THERAPY | PERIPHERAL-BLOOD | IMMUNOLOGY | DISEASE-ACTIVITY | BAFF-R | DIFFERENTIATION | RECONSTITUTION | LYMPHOCYTE DEPLETION | B-Cell Maturation Antigen - immunology | B-Lymphocyte Subsets - pathology | Arthritis, Rheumatoid - blood | Gene Expression Regulation - immunology | B-Cell Activation Factor Receptor - blood | Immunologic Memory - drug effects | Arthritis, Rheumatoid - pathology | Gene Expression Regulation - drug effects | Rituximab - administration & dosage | B-Lymphocyte Subsets - metabolism | Arthritis, Rheumatoid - drug therapy | Transmembrane Activator and CAML Interactor Protein - blood | B-Cell Activating Factor - immunology | B-Lymphocyte Subsets - immunology | B-Cell Activating Factor - blood | Arthritis, Rheumatoid - immunology | Transmembrane Activator and CAML Interactor Protein - immunology | B-Cell Maturation Antigen - blood | Immunologic Memory - immunology | B-Cell Activation Factor Receptor - immunology | Autoimmunity | Antimitotic agents | Rheumatoid factor | Care and treatment | Relapse | Arthritis | Genetic aspects | B cells | Antineoplastic agents | Diseases | Spleen | Binding | Lymphocyte receptors | Immunoglobulins | Memory cells | Immunological memory | Calcium | Rituximab | Cell differentiation | Patients | Calcium signalling | Serum levels | Receptors | Lymphocytes B | BLyS protein | Rheumatoid arthritis | CD38 antigen | Index Medicus | Original
Journal Article
Clinical Immunology, ISSN 1521-6616, 2016, Volume 164, pp. 85 - 94
Journal Article
Journal Article