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PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, p. e83139
CD28, CTLA-4 and PD-L1, the three identified ligands for CD80/86, are pivotal positive and negative costimulatory molecules that, among other functions,... 
IN-VITRO | ACTIVATION | HOMEOSTASIS | DENDRITIC CELLS | TOLERANCE | MULTIDISCIPLINARY SCIENCES | EXTRINSIC CONTROL | ANTI-CD28 ANTIBODY | UP-REGULATION | CUTTING EDGE | LYMPHOCYTES | B7-1 Antigen - antagonists & inhibitors | Cell Communication - immunology | B7-2 Antigen - genetics | B7-1 Antigen - genetics | Dendritic Cells - immunology | Humans | Molecular Targeted Therapy | T-Lymphocytes, Regulatory - immunology | T-Lymphocytes, Cytotoxic - drug effects | CD28 Antigens - genetics | Protein Binding - drug effects | CD28 Antigens - antagonists & inhibitors | T-Lymphocytes, Regulatory - cytology | Dendritic Cells - drug effects | B7-2 Antigen - immunology | T-Lymphocytes, Cytotoxic - immunology | Gene Expression | B7-2 Antigen - antagonists & inhibitors | B7-1 Antigen - immunology | Antibodies, Monoclonal - pharmacology | CTLA-4 Antigen - genetics | CD28 Antigens - immunology | CTLA-4 Antigen - immunology | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | Cell Movement - drug effects | T-Lymphocytes, Regulatory - drug effects | B7-H1 Antigen - antagonists & inhibitors | Lymphocyte Activation - drug effects | Cell Communication - drug effects | Dendritic Cells - cytology | CTLA-4 Antigen - antagonists & inhibitors | T-Lymphocytes, Cytotoxic - cytology | Viral antibodies | Antibodies | Antigens | B cells | T cells | Motility | Transplants & implants | Calcium | Blocking antibodies | Homeostasis | Effector cells | Reversing | Immunological synapses | Lymphocytes T | Kinases | CD28 antigen | T-cell receptor | CTLA-4 protein | Cell activation | Immunology | Lymphocytes | Dwell time | Cell cycle | Cytokines | Immunoregulation | CD80 antigen | T cell receptors | Costimulator | Microscopy | Antigen-presenting cells | PD-L1 protein | Ligands | Cell migration | Synapses | Apoptosis | Life Sciences | Human health and pathology
Journal Article
Molecular Therapy, ISSN 1525-0016, 07/2017, Volume 25, Issue 7, pp. 1676 - 1685
Targeted approaches to treat autoimmune diseases would improve upon current therapies that broadly suppress the immune system and lead to detrimental side... 
tolerance induction mechanism | antigen-specific tolerance | immune tolerance | PLGA | PLG nanoparticles | MEDICINE, RESEARCH & EXPERIMENTAL | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | DENDRITIC CELLS | ANTIGENS | IL-10 | IMMUNOLOGICAL-TOLERANCE | DELIVERY | RESPONSES | MULTIPLE-SCLEROSIS | PATHWAY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | CROSS-PRESENTATION | B7-2 Antigen - genetics | Myelin Proteolipid Protein - immunology | B7-1 Antigen - genetics | Spleen - immunology | Nanoparticles - chemistry | Ovalbumin - immunology | Encephalomyelitis, Autoimmune, Experimental - immunology | Delayed-Action Preparations - chemistry | Spleen - drug effects | Polyglactin 910 - metabolism | T-Lymphocytes, Regulatory - pathology | Delayed-Action Preparations - administration & dosage | Myelin Proteolipid Protein - pharmacology | T-Lymphocytes, Regulatory - immunology | Antigen-Presenting Cells - pathology | Immunoconjugates - pharmacology | Female | CD40 Antigens - genetics | Encephalomyelitis, Autoimmune, Experimental - genetics | Polyglactin 910 - chemistry | B7-2 Antigen - immunology | Myelin Proteolipid Protein - chemistry | Spleen - pathology | Ovalbumin - chemistry | Immune Tolerance - drug effects | Gene Expression | Encephalomyelitis, Autoimmune, Experimental - pathology | B7-1 Antigen - immunology | Immunoconjugates - metabolism | Antigen-Presenting Cells - drug effects | Mice, Inbred C57BL | Ovalbumin - pharmacology | Antigen-Presenting Cells - immunology | Immunoconjugates - chemistry | Antigens - chemistry | Particle Size | Encephalomyelitis, Autoimmune, Experimental - therapy | T-Lymphocytes, Regulatory - drug effects | Animals | Antigens - immunology | Mice | Nanoparticles - administration & dosage | Primary Cell Culture | Antigens - pharmacology | CD40 Antigens - immunology | Cell proliferation | Multiple sclerosis | Transcription factors | CD40 antigen | Disease | Peptides | CD86 antigen | Lymphocytes T | Nanoparticles | Myelin proteolipid protein | Lymphocytes | Localization | Immune system | Antigen presentation | Cytokines | Dendritic cells | Myelin | CD80 antigen | Inflammation | T cell receptors | Immunological tolerance | Studies | Major histocompatibility complex | Antigen-presenting cells | Internalization | PD-L1 protein | Proteolipid protein | Poly(lactide-co-glycolide) | Autoimmune diseases | Apoptosis | Original
Journal Article
Journal Article
Clinical Immunology, ISSN 1521-6616, 2015, Volume 160, Issue 1, pp. 103 - 123
Journal Article
Journal of Immunology, ISSN 0022-1767, 03/2014, Volume 192, Issue 6, pp. 2699 - 2714
The long-held paradigm that B cells cannot uptake nonspecific particulate Ags for the initiation of primary adaptive immunity has been challenged by the recent... 
MICROBICIDAL ABILITIES | ZEBRAFISH | DENDRITIC CELLS | EARLY VERTEBRATES | INFECTION | IMMUNOLOGY | EXPRESSION | T-CELLS | RELEVANT GENES | ANTIGEN | LYMPHOCYTES | Antigens, CD - immunology | B7-2 Antigen - genetics | B7-1 Antigen - genetics | Zebrafish - immunology | Immunoglobulins - immunology | Membrane Glycoproteins - metabolism | Molecular Sequence Data | Male | B7 Antigens - immunology | Gene Expression Profiling | Immunoglobulins - genetics | Phylogeny | Antigens, CD - genetics | Adaptive Immunity - genetics | Antigens, CD - metabolism | CD4-Positive T-Lymphocytes - immunology | Immunoglobulins - metabolism | Lymphocyte Activation - immunology | B7 Antigens - genetics | Base Sequence | Zebrafish Proteins - immunology | B-Lymphocyte Subsets - immunology | Female | Membrane Glycoproteins - immunology | Adaptive Immunity - immunology | B7-2 Antigen - immunology | B-Lymphocytes - metabolism | Amino Acid Sequence | Antigen-Presenting Cells - metabolism | Vibrio alginolyticus - immunology | B7-1 Antigen - immunology | Zebrafish Proteins - metabolism | CD4-Positive T-Lymphocytes - metabolism | B7-1 Antigen - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Antigen-Presenting Cells - immunology | Blotting, Western | Zebrafish - genetics | B7 Antigens - metabolism | Membrane Glycoproteins - genetics | Sequence Homology, Amino Acid | B7-2 Antigen - metabolism | Animals | B-Lymphocytes - immunology | B-Lymphocyte Subsets - metabolism | Zebrafish Proteins - genetics | Evolution, Molecular
Journal Article