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Autophagy, ISSN 1554-8627, 07/2008, Volume 4, Issue 5, pp. 600 - 606
The essential autophagy protein and haplo-insufficient tumor suppressor, Beclin 1, interacts with several cofactors (Ambra1, Bif-1, UVRAG) to activate the... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Bcl-2 | Bcl-xL | BH3-only proteins | Autophagy | Beclin 1 | Apoptosis | COMPLEX | DOMAIN | autophagy | PROTEIN | apoptosis | CANCER | CELL-DEATH | CELL BIOLOGY | INHIBITION | BECLIN-1 | INOSITOL TRISPHOSPHATE RECEPTOR | TUMOR-SUPPRESSOR | TUMORIGENESIS
Journal Article
Developmental Cell, ISSN 1534-5807, 2011, Volume 21, Issue 1, pp. 92 - 101
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 2018, Volume 25, Issue 1, pp. 37 - 45
Almost 30 years ago it was first appreciated that anti-apoptotic B-cell lymphoma-2 (BCL-2) prevents the induction of apoptosis not only in malignant cells, but... 
PROGRAMMED CELL-DEATH | SURVIVAL | ANTIAPOPTOTIC MCL-1 | NERVOUS-SYSTEM | POLYCYSTIC KIDNEY | PROTEIN | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | NEURONS | EXPRESSION | CELL BIOLOGY | Embryogenesis | Bcl-2 protein | Lymphocytes B | Cell death | Hematopoiesis | Homeostasis | Pharmacology | Neurogenesis | Hemopoiesis | Apoptosis | B-cell lymphoma | Review
Journal Article
2010, Advances in experimental medicine and biology, ISBN 1441967052, Volume 687., xvii, 145
This book highlights the relevance of the BCL‑2 family of proteins in apoptosis, physiology and disease. It examines the potential therapeutic benefits of... 
pathology | physiology | metabolism | Proto-Oncogene Proteins c-bcl-2 | Tumor proteins | Neoplasms | Apoptosis
Book
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2014, Volume 111, Issue 23, pp. 8512 - 8517
Antiapoptotic B-cell lymphoma 2 (Bcl-2) family members such as Bcl-2, myeloid cell leukemia 1 (Mcl-1), and B-cell lymphoma-X large (Bcl-xL) are proposed to... 
Myeloid cells | Starvation | Cell death | Cell lines | Fibroblasts | Cultured cells | Gene expression regulation | Viability | Family members | Apoptosis | ABT-737 | LC3B | LC3 | BH3 mimetic | Bim | SURVIVAL | APOPTOSIS | MCL-1 | MULTIDISCIPLINARY SCIENCES | KINASE | CELL-DEATH | CONNECTION | BECLIN-1 | ROLES | BH3-ONLY PROTEINS | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | bcl-2 Homologous Antagonist-Killer Protein - genetics | Cell Survival - genetics | Apoptosis - genetics | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Autophagy | Proto-Oncogene Proteins c-bcl-2 - metabolism | Flow Cytometry | Biphenyl Compounds - pharmacology | Nitrophenols - pharmacology | RNA Interference | bcl-2-Associated X Protein - genetics | Fibroblasts - metabolism | Phagosomes - metabolism | Cells, Cultured | bcl-2-Associated X Protein - metabolism | Sulfonamides - pharmacology | Piperazines - pharmacology | Blotting, Western | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Mice, Knockout | Animals | Autophagy-Related Protein 5 | Embryo, Mammalian - cytology | Fibroblasts - drug effects | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Fibroblasts - cytology | Mice | Proto-Oncogene Proteins c-bcl-2 - genetics | Cell Line, Transformed | Autophagy (Cytology) | Cell research | Oncology, Experimental | Physiological aspects | Lymphomas | Research | B cells | Health aspects | Cancer | Biological Sciences
Journal Article
Leukemia, ISSN 0887-6924, 03/2016, Volume 30, Issue 3, pp. 761 - 764
INHIBITION | ONCOLOGY | MCL-1 | DEATH | LEUKEMIA | HEMATOLOGY | ABT-199 | ADDICTION | Recurrence | Antineoplastic Agents - chemical synthesis | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | bcl-X Protein - genetics | Male | Plasma Cells - pathology | Plasma Cells - drug effects | Proto-Oncogene Proteins c-bcl-2 - metabolism | Peptides - chemical synthesis | bcl-X Protein - antagonists & inhibitors | Aged, 80 and over | Biological Assay | Female | Plasma Cells - metabolism | Antineoplastic Agents - pharmacology | Bridged Bicyclo Compounds, Heterocyclic - chemical synthesis | Myeloid Cell Leukemia Sequence 1 Protein - antagonists & inhibitors | Aniline Compounds - pharmacology | Cytochromes c - secretion | Multiple Myeloma - diagnosis | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondria - pathology | Multiple Myeloma - metabolism | Organ Specificity | Sulfonamides - pharmacology | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Peptides - pharmacology | Sulfonamides - chemical synthesis | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Multiple Myeloma - pathology | Cell Line, Tumor | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Aged | bcl-X Protein - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Aniline Compounds - chemical synthesis | Multiple Myeloma - genetics | Drug metabolism | Development and progression | Genetic aspects | Tumor proteins | Health aspects | Multiple myeloma | Life Sciences | Cancer | BCL-2 | BH3 profiling | BH3 mimetics | Multiple Myeloma | Apoptosis
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 01/2018, Volume 19, Issue 1, p. 308
Anti-apoptotic B cell lymphoma 2 (BCL2) family members (BCL2, MCL1, BCLxL, BCLW, and BFL1) are key players in the regulation of intrinsic apoptosis.... 
Alternative splicing | MicroRNA | MRNA stability | MRNA subcellular localization | Anti-apoptotic BCL2 subfamily | Post-transcriptional regulation | Apoptosis | RNA binding proteins | alternative splicing | post-transcriptional regulation | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | apoptosis | INDUCE APOPTOSIS | CELL-CYCLE CONTROL | RNA-BINDING-PROTEIN | COMPLEX NETWORK | CHEMISTRY, MULTIDISCIPLINARY | HEPATOCELLULAR-CARCINOMA | anti-apoptotic BCL2 subfamily | MESSENGER-RNA | DEPENDENT REGULATION | CANCER DEVELOPMENT | microRNA | mRNA subcellular localization | mRNA stability | PROMOTES APOPTOSIS | Multigene Family | RNA Transport | Alternative Splicing | RNA Processing, Post-Transcriptional | Humans | RNA, Messenger - genetics | Gene Expression Regulation, Neoplastic | Heterogeneous-Nuclear Ribonucleoproteins - metabolism | Apoptosis - genetics | RNA Stability | RNA, Messenger - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Animals | MicroRNAs - genetics | Proto-Oncogene Proteins c-bcl-2 - genetics | RNA-Binding Proteins - metabolism | Post-transcription | Bcl-2 protein | Splicing | Gene regulation | mRNA turnover | Crosstalk | Homeostasis | Gene expression | Ribonucleic acid--RNA | Lymphoma | Disease control | Mcl-1 protein | Proteins | RNA-binding protein | Lymphocytes B | miRNA | Localization | Cancer
Journal Article
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 12/2007, Volume 13, Issue 24, pp. 7264 - 7270
Journal Article