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Autophagy, ISSN 1554-8635, 2008, Volume 4, Issue 5, pp. 600 - 606
The essential autophagy protein and haplo-insufficient tumor suppressor, Beclin 1, interacts with several cofactors (Ambra1, Bif-1, UVRAG) to activate the... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Bcl-2 | Bcl-xL | BH3-only proteins | Autophagy | Beclin 1 | Apoptosis | COMPLEX | DOMAIN | autophagy | apoptosis | CLASSIFICATION | MECHANISMS | INDUCTION | CELL-DEATH | CELL BIOLOGY | INHIBITION | BECLIN-1 | PROTEINS | TUMORIGENESIS
Journal Article
Cell death and differentiation, ISSN 1476-5403, 2017, Volume 25, Issue 1, pp. 37 - 45
.... This critical observation has rapidly evolved from merely identifying new BCL-2 family members to understanding how their biochemical interactions trigger the cell death process, and, more recently... 
PROGRAMMED CELL-DEATH | SURVIVAL | ANTIAPOPTOTIC MCL-1 | NERVOUS-SYSTEM | POLYCYSTIC KIDNEY | PROTEIN | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | NEURONS | EXPRESSION | CELL BIOLOGY | Embryogenesis | Bcl-2 protein | Lymphocytes B | Cell death | Hematopoiesis | Homeostasis | Pharmacology | Neurogenesis | Hemopoiesis | Apoptosis | B-cell lymphoma | Review
Journal Article
Developmental cell, ISSN 1534-5807, 2011, Volume 21, Issue 1, pp. 92 - 101
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 6/2014, Volume 111, Issue 23, pp. 8512 - 8517
Antiapoptotic B-cell lymphoma 2 (Bcl-2) family members such as Bcl-2, myeloid cell leukemia 1 (Mcl-1... 
Myeloid cells | Starvation | Cell death | Cell lines | Fibroblasts | Cultured cells | Gene expression regulation | Viability | Family members | Apoptosis | ABT-737 | LC3B | LC3 | BH3 mimetic | Bim | SURVIVAL | APOPTOSIS | MCL-1 | MULTIDISCIPLINARY SCIENCES | KINASE | CELL-DEATH | CONNECTION | BECLIN-1 | ROLES | BH3-ONLY PROTEINS | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | bcl-2 Homologous Antagonist-Killer Protein - genetics | Cell Survival - genetics | Apoptosis - genetics | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Autophagy | Proto-Oncogene Proteins c-bcl-2 - metabolism | Flow Cytometry | Biphenyl Compounds - pharmacology | Nitrophenols - pharmacology | RNA Interference | bcl-2-Associated X Protein - genetics | Fibroblasts - metabolism | Phagosomes - metabolism | Cells, Cultured | bcl-2-Associated X Protein - metabolism | Sulfonamides - pharmacology | Piperazines - pharmacology | Blotting, Western | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Mice, Knockout | Animals | Autophagy-Related Protein 5 | Embryo, Mammalian - cytology | Fibroblasts - drug effects | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Fibroblasts - cytology | Mice | Proto-Oncogene Proteins c-bcl-2 - genetics | Cell Line, Transformed | Autophagy (Cytology) | Cell research | Oncology, Experimental | Physiological aspects | Lymphomas | Research | B cells | Health aspects | Cancer | Biological Sciences
Journal Article
Leukemia, ISSN 1476-5551, 2015, Volume 30, Issue 3, pp. 761 - 764
INHIBITION | ONCOLOGY | MCL-1 | DEATH | LEUKEMIA | HEMATOLOGY | ABT-199 | ADDICTION | Recurrence | Antineoplastic Agents - chemical synthesis | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | bcl-X Protein - genetics | Male | Plasma Cells - pathology | Plasma Cells - drug effects | Proto-Oncogene Proteins c-bcl-2 - metabolism | Peptides - chemical synthesis | bcl-X Protein - antagonists & inhibitors | Aged, 80 and over | Biological Assay | Female | Plasma Cells - metabolism | Antineoplastic Agents - pharmacology | Bridged Bicyclo Compounds, Heterocyclic - chemical synthesis | Myeloid Cell Leukemia Sequence 1 Protein - antagonists & inhibitors | Aniline Compounds - pharmacology | Cytochromes c - secretion | Multiple Myeloma - diagnosis | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondria - pathology | Multiple Myeloma - metabolism | Organ Specificity | Sulfonamides - pharmacology | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Peptides - pharmacology | Sulfonamides - chemical synthesis | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Multiple Myeloma - pathology | Cell Line, Tumor | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Aged | bcl-X Protein - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Aniline Compounds - chemical synthesis | Multiple Myeloma - genetics | Drug metabolism | Development and progression | Genetic aspects | Tumor proteins | Health aspects | Multiple myeloma | Life Sciences | Cancer | BCL-2 | BH3 profiling | BH3 mimetics | Multiple Myeloma | Apoptosis
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 12/2007, Volume 13, Issue 24, pp. 7264 - 7270
Journal Article
Autophagy, ISSN 1554-8627, 11/2007, Volume 3, Issue 6, pp. 561 - 568
Journal Article
PloS one, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, p. e80625
... processes, including cancer. By combining 5 independent genome-wide expression profiling experiments, we identified a panel of 266 unique transcripts that were down-regulated in epithelial cells transfected with miR-99 family members... 
MIR-100 | AXIAL SKELETON | HUMAN GROWTH-HORMONE | METASTASIS | MAMMARY-CARCINOMA CELLS | MULTIDISCIPLINARY SCIENCES | DOWN-REGULATION | ONCOGENIC TRANSFORMATION | HOX GENES | UP-REGULATION | CANCER | Cell Line | Genome-Wide Association Study | Homeodomain Proteins - biosynthesis | Humans | Gene Expression Regulation - physiology | MicroRNAs - biosynthesis | Proto-Oncogene Proteins - genetics | Transcription Factors - biosynthesis | Gene Expression Profiling | Transcription Factors - genetics | Proto-Oncogene Proteins - biosynthesis | Homeodomain Proteins - genetics | MicroRNAs - genetics | MicroRNA | Homeobox genes | Epithelial cells | Luciferase | Physiological aspects | Research | Homeotic genes | Membrane proteins | TOR protein | Cell proliferation | Chromatin | Immunoprecipitation | Bcl-2 protein | Downstream effects | Genes | Genomes | Kinases | Tissues | Cell adhesion & migration | Gene sequencing | Maxillofacial surgery | Homeobox | Embryogenesis | N-Myristoyltransferase | Cell growth | Reporter gene | Transfection | Actin | Rodents | Surgery | Penicillin | miRNA | Physiology | Tumorigenesis | Bioinformatics | Wound healing | HOXA1 protein | Rapamycin | Dentistry | Gene expression | Ribonucleic acid--RNA | Embryonic growth stage | Studies | Oral diseases | Hospitals | Algorithms | MicroRNAs | Pancreatic cancer | Skin | Molecular biology | Cell migration | Apoptosis | Cancer | RNA | Ribonucleic acid | Healing
Journal Article
The Journal of cell biology, ISSN 0021-9525, 4/2009, Volume 185, Issue 2, pp. 279 - 290
It is still unclear whether the BH3-only protein Puma (p53 up-regulated modulator of apoptosis) can prime cells to death and render antiapoptotic BH3-binding... 
Proteins | Yeasts | Microinjections | Cell death | HCT116 cells | Cell lines | Antibodies | Cytochromes | Down regulation | Apoptosis | YEAST MITOCHONDRIA | ALPHA-HELIX | INTRACELLULAR-LOCALIZATION | X-L | DEATH | COLORECTAL-CANCER CELLS | MITOCHONDRIAL-MEMBRANE | BH3 DOMAINS | MEMBRANE PERMEABILIZATION | APOPTOTIC ACTIVITY | CELL BIOLOGY | Humans | Nitrophenols - metabolism | Piperazines - metabolism | Biphenyl Compounds - metabolism | Gene Knockdown Techniques | Proto-Oncogene Proteins c-bcl-2 - metabolism | Yeasts - physiology | Cyclin-Dependent Kinase Inhibitor p21 - genetics | RNA Interference | Apoptosis Regulatory Proteins - genetics | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Colorectal Neoplasms - metabolism | bcl-2-Associated X Protein - genetics | Proto-Oncogene Proteins - metabolism | bcl-2-Associated X Protein - metabolism | Proto-Oncogene Proteins - genetics | bcl-2-Associated X Protein - antagonists & inhibitors | Apoptosis Regulatory Proteins - metabolism | Myeloid Cell Leukemia Sequence 1 Protein | Sulfonamides - metabolism | Cell Line, Tumor | Protein Binding | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Apoptosis - physiology | Proto-Oncogene Proteins c-bcl-2 - genetics | Physiological aspects | Cellular proteins | Genetic aspects | Research | Life Sciences | Cellular Biology
Journal Article