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Cancer Discovery, ISSN 2159-8274, 03/2019, Volume 9, Issue 3, pp. 323 - 325
Standard treatment for estrogen receptor-positive metastatic breast cancer involves antiestrogen therapy used alone or in combination with inhibitors of CDK4/6... 
ONCOLOGY | BCL2
Journal Article
Expression of Bcl2 Proto-oncogene in Primary Tumors of the Central Nervous System, 12/2002
The present study was addressed to find out the expression of Bcl2 proto-oncogene in tumor tissues derived from 25 patients with primary central nervous system... 
Apoptosis, Bcl2, Proto-oncogene, Proliferation
Journal
Expression of Bcl2 Proto-oncogene in Primary Tumors of the Central Nervous System, 12/2002
The present study was addressed to find out the expression of Bcl2 proto-oncogene in tumor tissues derived from 25 patients with primary central nervous system... 
Apoptosis, Bcl2, Proto-oncogene, Proliferation
Journal
HAEMATOLOGICA, ISSN 0390-6078, 08/2018, Volume 103, Issue 9, pp. 1511 - 1517
Venetoclax is a BCL2 inhibitor approved for 17 deleted relapsed/refractory chronic lymphocytic leukemia with activity following kinase inhibitors. We conducted... 
MULTICENTER | CLL | IBRUTINIB | BCL2 | HEMATOLOGY
Journal Article
BLOOD, ISSN 0006-4971, 07/2019, Volume 134, Issue 2, pp. 111 - 122
To define the efficacy of venetoclax with extended follow-up and identify clinical or biological treatment effect modifiers, updated data for previously... 
BCL2 | CLL | INHIBITOR | HEMATOLOGY | RITUXIMAB
Journal Article
05/2010
Background: This study was conducted to analyze the frequency, expression patterns, and the impact of individual proteins BCL2, BCL6, and p53 on overall... 
BCL2/IGH translocation | DLBCL | BCL6 | BCL2 | overall survival | p53
Web Resource
Journal Article
Journal of Cell Science, ISSN 0021-9533, 03/2012, Volume 125, Issue 6, pp. 1568 - 1578
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 09/2018, Volume 24, Issue 18, pp. 4371 - 4379
Purpose: The oral BCL-2 inhibitor venetoclax is an effective therapy for patients with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL), including... 
BCL2 | LYMPHOMA | ONCOLOGY | INHIBITOR | PHASE-I | TUMOR LYSIS SYNDROME
Journal Article
Meta Gene, ISSN 2214-5400, 12/2018, Volume 18, pp. 137 - 142
Bladder cancer (BC) is a frequent cancer with high morbidity and mortality. We assessed expression of , , and in BC samples, adjacent non-neoplastic tissues... 
BCL2 | BAX | BAG3 | NMP22
Journal Article
The American Journal of Surgical Pathology, ISSN 0147-5185, 09/2015, Volume 39, Issue 9, pp. 1250 - 1258
Journal Article
Genes and Development, ISSN 0890-9369, 02/2009, Volume 23, Issue 3, pp. 278 - 290
p53 is a well-known tumor suppressor and is also involved in processes of organismal aging and developmental control. A recent exciting development in the p53... 
Bcl2 | Zebrafish | P53 isoforms | Δ113p53 | Apoptosis | p53 isoforms | apoptosis | Research Paper | zebrafish
Journal Article
American Journal of Surgical Pathology, ISSN 0147-5185, 01/2016, Volume 40, Issue 1, pp. 127 - 136
The classification of cutaneous follicular lymphoma (CFL) into primary cutaneous follicle center lymphoma (PCFCL) or secondary cutaneous follicular lymphoma... 
BCL2 | FISH | BCL2 rearrangement | primary cutaneous follicle center lymphoma | stathmin | del 1p36 | Life Sciences | Human health and pathology | Surgery
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 01/2019, Volume 37, Issue 3, pp. 175 - 177
Journal Article
Current Drug Targets, ISSN 1389-4501, 2013, Volume 14, Issue 1, pp. 90 - 101
Journal Article
Oncotarget, ISSN 1949-2553, 2018, Volume 9, Issue 40, pp. 26046 - 26063
Cancer cells display differences regarding their engagement of glycolytic vs. mitochondrial oxidative phosphorylation (OXPHOS) pathway. Triple negative breast... 
OXPHOS | Breast cancer | Bioenergetics | Cell death | BCL2 inhibitors
Journal Article
Autophagy, ISSN 1554-8627, 03/2015, Volume 11, Issue 3, pp. 452 - 459
Disruption of the complex of BECN1 with BCL2 or BCL2L1/BCL-X L is an essential switch that turns on cellular autophagy in response to environmental stress or... 
STS, staurosporine | apoptosis | MAP1LC3/LC3, microtubule-associated protein 1 light chain 3 | HRP, horseradish peroxidase | PBS, phosphate-buffered saline | BAK1 | HBSS, Hanks' balanced salt solution | BCL2, B-cell CLL/lymphoma 2 | GAPDH, glyceraldehyde-3-phosphate dehydrogenase | Baf A1, bafilomycin A | MTOR, mechanistic target of rapamycin | autophagy | ACTB, actin, β | FBS, fetal bovine serum | WT, wild type | ABT-737 | BECN1 (Beclin 1) | BECN1, Beclin 1, autophagy-related | DKO, double-knockout | SQSTM1, sequestosome 1 | BAX, BCL2-associated X protein | BCL2 | BAX | MEFs, mouse embryonic fibroblasts | MCL1, myeloid cell leukemia 1 | BAK1, BCL2-antagonist/killer 1 | Autophagy | Apoptosis | bafilomycin A | sequestosome 1 | HRP | BCL2-associated X protein | mechanistic target of rapamycin | phosphate-buffered saline | ACTB | PEPTIDE | CELL BIOLOGY | 1 PHOSPHORYLATION | STS | FBS | X-L | autophagy-related | horseradish peroxidase | Hanks' balanced salt solution | mouse embryonic fibroblasts | LC3 | MOLECULAR-BASIS | PBS | MEFs | BECLIN 1-DEPENDENT AUTOPHAGY | killer 1 | lymphoma 2 | BH3-ONLY PROTEIN | DKO | double-knockout | MAP1LC3 | fetal bovine serum | actin | BCL2-antagonist | wild type | GAPDH | SQSTM1 | BECN1 | staurosporine | myeloid cell leukemia 1 | Baf A1 | BH3 DOMAIN | microtubule-associated protein 1 light chain 3 | glyceraldehyde-3-phosphate dehydrogenase | B-cell CLL | BCL-2 FAMILY-MEMBERS | MCL1 | SUPPRESSION | MTOR | Beclin 1 | HBSS | Beclin-1 | Peptide Fragments | Sulfonamides - chemistry | HCT116 Cells | Humans | bcl-2-Associated X Protein - metabolism | Piperazines - chemistry | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Nitrophenols - chemistry | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Proto-Oncogene Proteins c-bcl-2 - metabolism | Animals | Flow Cytometry | Cell Line, Tumor | Protein Binding | Membrane Proteins - metabolism | Mice | Proto-Oncogene Proteins | Biphenyl Compounds - chemistry | Microscopy, Fluorescence | Fibroblasts - metabolism | Index Medicus
Journal Article
Pharmacogenomics, ISSN 1462-2416, 12/2017, Volume 18, Issue 18, pp. 1671 - 1682
Aim: Previous observations have implicated miR-509-3p's ability in regulating cisplatin-triggered apoptosis in ovarian cancer. However, the underlying... 
BCL2 | microRNA-509-3p | apoptosis | ovarian cancer | MIGRATION | SURVIVAL | MCL-1 | PROLIFERATION | MICRORNAS | BCL2 FAMILY | THERAPY | GASTRIC-CANCER | TARGETS | PHARMACOLOGY & PHARMACY
Journal Article
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