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1. Full Text The C421A (Q141K) polymorphism enhances the 3′-untranslated region (3′-UTR)-dependent regulation of ATP-binding cassette transporter ABCG2
by Ripperger, Anne and Benndorf, Ralf A
Biochemical pharmacology, ISSN 0006-2952, 03/2016, Volume 104, pp. 139 - 147
hsa-miR-520h | C421A (Q141K) variant | ATP-binding cassette (ABC) transporter | hsa-miR-519c | microRNA | ABCG2/BCRP | Single nucleotide polymorphism | hsa-miR-328 | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Protein Biosynthesis | Mutagenesis, Site-Directed | Humans | 3' Untranslated Regions - genetics | Neoplasm Proteins - chemistry | Neoplasm Proteins - metabolism | Blotting, Western | Microscopy, Confocal | ATP-Binding Cassette Transporters - chemistry | Flow Cytometry | Transfection | ATP-Binding Cassette Transporters - genetics | HEK293 Cells | ATP-Binding Cassette Transporters - metabolism | MicroRNAs - genetics | Polymorphism, Single Nucleotide | Cell Culture Techniques | Mutation | Protein Stability | Neoplasm Proteins - genetics | Binding Sites | Real-Time Polymerase Chain Reaction | Index Medicus
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2. Full Text BCRP/ABCG2 in the Placenta: Expression, Function and Regulation
by Mao, Qingcheng
Pharmaceutical research, ISSN 0724-8741, 6/2008, Volume 25, Issue 6, pp. 1244 - 1255
Biomedical Engineering | Biochemistry, general | Biomedicine | Pharmacy | BCRP/ ABCG2 | pregnancy | Medical Law | placenta | Pharmacology/Toxicology | ABC transporter | fetus | Pregnancy | Fetus | Placenta | BCRP/ABCG2 | Pharmacology & Pharmacy | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Pharmaceutical technology. Pharmaceutical industry | Biological and medical sciences | Medical sciences | General pharmacology | Pharmacology. Drug treatments | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation | ATP-Binding Cassette Transporters - physiology | ATP-Binding Cassette Transporters - analysis | Polymorphism, Genetic | ATP-Binding Cassette Transporters - genetics | Biological Transport | Female | Neoplasm Proteins - analysis | Placenta - chemistry | Neoplasm Proteins - genetics | Toxicology | Pharmacology | Gene expression | Drug therapy | Prenatal care | Human exposure | Index Medicus | BCRP | Expert Review | ABCG2
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3. Full Text Interindividual Regulation of the Breast Cancer Resistance Protein/ABCG2 Transporter in Term Human Placentas
by Bircsak, Kristin M and Moscovitz, Jamie E and Wen, Xia and Archer, Faith and Yuen, Poi Yu Sofia and Mohammed, Moiz and Memon, Naureen and Weinberger, Barry I and Saba, Laura M and Vetrano, Anna M and Aleksunes, Lauren M
Drug metabolism and disposition, ISSN 0090-9556, 05/2018, Volume 46, Issue 5, pp. 619 - 627
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | European Continental Ancestry Group - genetics | Hispanic Americans - genetics | Humans | RNA, Messenger - genetics | ATP Binding Cassette Transporter, Subfamily G, Member 2 - genetics | Asian Continental Ancestry Group - genetics | African Americans - genetics | Genotype | Breast Neoplasms - metabolism | Placenta - metabolism | Pregnancy | Breast Neoplasms - genetics | Alleles | Polymorphism, Single Nucleotide - genetics | Adult | Female | Neoplasm Proteins - genetics | Efflux | Transcription factors | Fetuses | BCRP protein | Breast cancer | Infants | Single-nucleotide polymorphism | Gene expression | Gene polymorphism | Chemicals | Proteins | Placenta | Aromatic compounds | Protein folding | Genetic analysis | Regulation | Protein transport | Transporter | Genotypes | Deoxyribonucleic acid--DNA | Cancer | Polymorphism | Index Medicus | Special Section on Transporters in Drug Disposition and Pharmacokinetic Prediction
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4. Full Text Regulation of BCRP (ABCG2) and P-Glycoprotein (ABCB1) by Cytokines in a Model of the Human Blood–Brain Barrier
by Poller, Birk and Poller, Birk and Drewe, Jürgen and Drewe, Jürgen and Krähenbühl, Stephan and Krähenbühl, Stephan and Huwyler, Jörg and Huwyler, Jörg and Gutmann, Heike and Gutmann, Heike
Cellular and molecular neurobiology, ISSN 0272-4340, 1/2010, Volume 30, Issue 1, pp. 63 - 70
BCRP | Neurosciences | Tumor necrosis factor-alpha | Biomedicine | P-Glycoprotein | Animal Anatomy / Morphology / Histology | Interleukin-1 beta | Blood–brain barrier | Interleukin-6 | Blood-brain barrier | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Cell Line | Interleukin-1beta - pharmacology | Humans | RNA, Messenger - genetics | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | Blood-Brain Barrier - drug effects | Blood-Brain Barrier - metabolism | Gene Expression Regulation - drug effects | Rhodamine 123 - metabolism | Tumor Necrosis Factor-alpha - pharmacology | ATP-Binding Cassette Transporters - genetics | Interleukin-6 - pharmacology | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Models, Biological | ATP-Binding Cassette Transporters - metabolism | Mitoxantrone - pharmacology | Neoplasm Proteins - genetics | Cytokines - pharmacology | Index Medicus
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5. Full Text Down-regulation of the placental BCRP/ ABCG2 transporter in response to hypoxia signaling
by Francois, Lissa N and Gorczyca, Ludwik and Du, Jianyao and Bircsak, Kristin M and Yen, Elizabeth and Wen, Xia and Tu, Mei-Juan and Yu, Ai-Ming and Illsley, Nicholas P and Zamudio, Stacy and Aleksunes, Lauren M
Placenta (Eastbourne), ISSN 0143-4004, 2017, Volume 51, pp. 57 - 63
Internal Medicine | Obstetrics and Gynecology | BCRP | Hypoxia | Placenta | Transporter | ABCG2 | Life Sciences & Biomedicine | Developmental Biology | Obstetrics & Gynecology | Reproductive Biology | Science & Technology | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Down-Regulation | Humans | Glucose Transporter Type 1 - metabolism | Vascular Endothelial Growth Factor A - metabolism | Neoplasm Proteins - metabolism | Vascular Endothelial Growth Factor A - genetics | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - metabolism | Hypoxia - metabolism | Placenta - drug effects | Placenta - metabolism | Pregnancy | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - genetics | Hypoxia - genetics | Cobalt - pharmacology | Glucose Transporter Type 1 - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Cell Line, Tumor | Female | Signal Transduction - physiology | Neoplasm Proteins - genetics | Drugstores | Medical colleges | Research institutes | Pharmacy | Index Medicus | hypoxia | placenta | transporter
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6. Full Text A role for ABCG2 beyond drug transport: Regulation of autophagy
by Ding, Rui and Jin, Shengkan and Pabon, Kirk and Scotto, Kathleen W
Autophagy, ISSN 1554-8627, 05/2016, Volume 12, Issue 5, pp. 737 - 751
BCRP | drug transporters | amino acid starvation | multidrug resistance | autophagy | radiation | ABC transporters | tumor cell survival | ABCG2 | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Survival - drug effects | Microtubule-Associated Proteins - genetics | Apoptosis - drug effects | Microtubule-Associated Proteins - metabolism | Humans | RNA, Small Interfering - pharmacology | Apoptosis - genetics | Neoplasm Proteins - metabolism | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - metabolism | Autophagy - drug effects | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - genetics | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Neoplasm Proteins - genetics | Index Medicus
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7. Full Text Acute regulation of apical ABC transporters in the gut. Potential influence on drug bioavailability
by Domínguez, Camila Juliana and Tocchetti, Guillermo Nicolás and Rigalli, Juan Pablo and Mottino, Aldo Domingo
Pharmacological research, ISSN 1043-6618, 01/2021, Volume 163, pp. 105251 - 105251
BCRP | Intestinal barrier | MDR1 | MRP2 | ABC transporters | Acute regulation | Short-term modulation | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Drugs | Drug resistance in microorganisms | Drug delivery systems | Xenobiotics | Food contamination | Vehicles | Index Medicus
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8. Full Text Transcription factor-mediated regulation of the BCRP/ABCG2 efflux transporter: a review across tissues and species
by Gorczyca, Ludwik and Aleksunes, Lauren M
Expert opinion on drug metabolism & toxicology, ISSN 1742-5255, 03/2020, Volume 16, Issue 3, pp. 239 - 253
Breast Cancer Resistance Protein (BCRP) | transcription | transporter | ABCG2 | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Toxicology | Life Sciences & Biomedicine | Science & Technology |