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Nature Medicine, ISSN 1078-8956, 09/2017, Volume 23, Issue 9, pp. 1072 - 1079
Aging is associated with increased cellular senescence, which is hypothesized to drive the eventual development of multiple comorbidities(1). Here we... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | SECRETORY PHENOTYPE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MATURE | IDENTIFICATION | CELL BIOLOGY | OSTEOCLASTOGENESIS | ACTIVATOR | MASS | ESTROGEN | FRACTURES | DYSFUNCTION | Osteocytes - drug effects | Cancellous Bone - metabolism | beta-Galactosidase | Cellular Senescence - drug effects | Apoptosis - genetics | Cancellous Bone - drug effects | Gene Expression Profiling | Osteoclasts - cytology | Bone and Bones - drug effects | Caspase 8 - genetics | Flow Cytometry | Osteoporosis - metabolism | Bone and Bones - metabolism | Osteoporosis - genetics | Cell Differentiation | Osteoblasts - cytology | Real-Time Polymerase Chain Reaction | Pyrazoles - pharmacology | Cellular Senescence - genetics | Osteoblasts - drug effects | Mice, Transgenic | Absorptiometry, Photon | Cortical Bone - metabolism | Janus Kinases - antagonists & inhibitors | Culture Media, Conditioned | Animals | Cortical Bone - drug effects | Weight-Bearing | Mice | In Vitro Techniques | Osteoclasts - drug effects | Prevention | Osteoporosis | Aging | Physiological aspects | Genetic aspects | Research | Cells | Senescence | Bone (trabecular) | Suicide | Bone resorption | Bone growth | Biomedical materials | Mineralization | Rodents | Computer architecture | Biocompatibility | Inhibition | Conditioning | Bone loss | Bone (cortical) | Suicide genes | Age | Cardiovascular system | Cell survival | Aging (artificial) | Caspase | Pharmacology | Secretome | Inflammation | Insulin | Osteoclastogenesis | Caspase-8 | Bone mass | Cellular biology | Sensitivity enhancement | Bone | In vitro methods and tests | Osteogenesis | Disease prevention | Osteoclast | Drug therapy | Osteocyte
Journal Article
Cancer Research, ISSN 0008-5472, 05/2010, Volume 70, Issue 9, pp. 3515 - 3525
Journal Article
Journal Article
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, ISSN 0363-6119, 02/2008, Volume 294, Issue 2, pp. R393 - R401
The Apc(Min/+) mouse has a mutation in the Apc tumor suppressor gene and develops intestinal polyps, beginning at 4 wk of age. This mouse develops cachexia by... 
EXPERIMENTAL CANCER CACHEXIA | polyps | PHYSIOLOGY | colorectal cancer | ATROPHY | cachexia | COLON-26 ADENOCARCINOMA | CYTOKINE | HUMAN SKELETAL-MUSCLE | IL-6 | ADENOCARCINOMA-BEARING MICE | METABOLISM | inflammation | IN-VIVO | STAT-3 | EXPRESSION
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 2010, Volume 120, Issue 7, pp. 2486 - 2496
Journal Article
European Journal of Immunology, ISSN 0014-2980, 04/2015, Volume 45, Issue 4, pp. 1148 - 1158
Immunosuppressive CD11b+Gr‐1+ myeloid‐derived suppressor cells (MDSCs) accumulate in the livers of tumor‐bearing (TB) mice. We studied hepatic MDSCs in two... 
CD40 | Reactive oxygen species | α‐Galactosylceramide | Immune‐mediated hepatitis | Concanavalin A | Myeloid‐derived suppressor cells | α-Galactosylceramide | Immune-mediated hepatitis | Myeloid-derived suppressor cells | NKT CELLS | OXIDATIVE STRESS | ALPHA-GALACTOSYLCERAMIDE | HEPATOCELLULAR-CARCINOMA PATIENTS | IMMUNOLOGY | INDUCED LIVER-INJURY | CONCANAVALIN-A | NECROSIS-FACTOR | KUPFFER CELLS | Galactosylceramide | BEARING MICE | T-CELLS | Reactive Oxygen Species - metabolism | Mitogens - pharmacology | Concanavalin A - pharmacology | Arginase - metabolism | Arginase - biosynthesis | Hepatocytes - pathology | Alanine Transaminase - blood | Adoptive Transfer | Galactosylceramides - pharmacology | Liver - injuries | CD40 Antigens - biosynthesis | CD40 Antigens - metabolism | Myeloid Cells - immunology | Hepatitis - genetics | Female | CD40 Antigens - genetics | Arginase - antagonists & inhibitors | B7-1 Antigen - biosynthesis | Cell Line | Mice, Inbred C57BL | Receptors, Chemokine - metabolism | Liver Neoplasms - immunology | Hepatocytes - immunology | Mice, Knockout | Animals | B7-2 Antigen - biosynthesis | Aspartate Aminotransferases - blood | Hepatitis - immunology | Myeloid Cells - transplantation | Antigens, CD1d - biosynthesis | Liver - cytology | Mice | Mice, Inbred BALB C | CD11b Antigen - metabolism | Hepatitis | Analysis | Tumors | Animal models | CD40 antigen | CD86 antigen | Liver | Effector cells | Arginase | Suppressor cells | Adoptive transfer | Rodents | Damage | Hepatotoxicity | Killing | Oxygen | Myeloid cells | CD11b antigen | Alanine | CD80 antigen | Inflammation | Serum levels | CD1d antigen | Immunosuppression | Hepatocytes | γ-Interferon | Alanine transaminase | Aspartate aminotransferase | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, p. e33179
Journal Article