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Nature (London), ISSN 1476-4687, 03/2019, Volume 567, Issue 7747, pp. 262 - 266
Cyclic GMP-AMP (cGAMP) synthase (cGAS) detects infections or tissue damage by binding to microbial or self DNA in the cytoplasm(1). Upon binding DNA, cGAS... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Nucleotides, Cyclic - metabolism | Interferons - biosynthesis | Beclin-1 - deficiency | Vesicular Transport Proteins - metabolism | Humans | Endoplasmic Reticulum - metabolism | Autophagy-Related Protein 5 - genetics | Autophagy-Related Protein-1 Homolog - metabolism | DNA Viruses - metabolism | Interferons - immunology | Autophagy | DNA Viruses - genetics | Sea Anemones | Membrane Proteins - deficiency | HEK293 Cells | Membrane Proteins - metabolism | Nucleotidyltransferases - metabolism | Protein-Serine-Threonine Kinases - metabolism | Phosphate-Binding Proteins | Signal Transduction | Membrane Proteins - genetics | DNA, Viral - metabolism | Class III Phosphatidylinositol 3-Kinases - metabolism | Autophagosomes - metabolism | Cytosol - virology | Protein Transport | Carrier Proteins - genetics | Animals | Autophagy-Related Protein-1 Homolog - deficiency | Carrier Proteins - metabolism | Monomeric GTP-Binding Proteins - metabolism | Autophagy-Related Protein 5 - deficiency | Autophagy-Related Protein 5 - metabolism | Beclin-1 - genetics | Golgi Apparatus - metabolism | Mice | Beclin-1 - metabolism | Autophagy-Related Protein-1 Homolog - genetics | Nucleotides, Cyclic - immunology | Evolution, Molecular | Biological research | Autophagy (Cytology) | Enzymes | Physiological aspects | Interferon | Research | Cytoplasm | Biology, Experimental | Index Medicus
Journal Article
Nature communications, ISSN 2041-1723, 05/2018, Volume 9, Issue 1, pp. 1944 - 12
Cancer recurrence after initial diagnosis and treatment is a major cause of breast cancer (BC) mortality, which results from the metastatic outbreak of dormant... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | RNA, Small Interfering - genetics | Recurrence | Reactive Oxygen Species - metabolism | Autophagy-Related Protein 7 - metabolism | Humans | Gene Expression Regulation, Neoplastic | Autophagy - drug effects | Reactive Oxygen Species - agonists | Breast Neoplasms - metabolism | Caspases - metabolism | Female | Autophagy - genetics | Mammary Neoplasms, Animal - genetics | Autophagy-Related Protein 7 - antagonists & inhibitors | Cell Survival - drug effects | Adenine - analogs & derivatives | Signal Transduction | Caspases - genetics | Beclin-1 - antagonists & inhibitors | Adenine - pharmacology | Lymphatic Metastasis | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondria - pathology | Autophagy-Related Protein 7 - genetics | Mammary Neoplasms, Animal - pathology | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Mice, Nude | Mammary Neoplasms, Animal - metabolism | Beclin-1 - genetics | Cell Line, Tumor | Hydroxychloroquine - pharmacology | Cell Proliferation - drug effects | Collagen Type I - pharmacology | Mammary Neoplasms, Animal - drug therapy | Mice | Beclin-1 - metabolism | RNA, Small Interfering - metabolism | Cell proliferation | Animal models | Cell survival | Outbreaks | Breast cancer | Pharmacology | Metastasis | Autophagy | Survival | Metastases | Dormancy | Signal transduction | Mitochondria | Inhibition | Damage accumulation | Phagocytosis | Cancer | Tumors | Apoptosis | Index Medicus
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 09/2017, Volume 292, Issue 39, pp. 16235 - 16248
Journal Article
Journal Article
Cellular physiology and biochemistry, ISSN 1421-9778, 2017, Volume 43, Issue 3, pp. 1126 - 1139
Journal Article
Journal Article