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Nature reviews. Molecular cell biology, ISSN 1471-0080, 2016, Volume 17, Issue 11, pp. 691 - 702
Journal Article
Molecular biology of the cell, ISSN 1939-4586, 2016, Volume 27, Issue 16, pp. 2523 - 2527
Journal Article
Biochimica et biophysica acta. Bioenergetics, ISSN 0005-2728, 2014, Volume 1837, Issue 7, pp. 1075 - 1082
The presence of two distinct types of adipose tissue, which have opposing functions, has been known for decades. White adipose tissue (WAT) is the main tissue... 
Rosiglitazone | Proton leak | Thermogenesis | Isoproterenol | Uncoupling protein 1 | Beige Adipocytes | BROWN-ADIPOSE-TISSUE | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DIET-INDUCED OBESITY | NONSHIVERING THERMOGENESIS | BIOPHYSICS | MITOCHONDRIAL UNCOUPLING PROTEIN | INSULIN-RESISTANCE | MICE | EXPRESSION | WHITE ADIPOCYTES | RNA | Gene expression | Analysis
Journal Article
Journal Article
Nature (London), ISSN 1476-4687, 2017, Volume 546, Issue 7656, pp. 107 - 112
Menopause is associated with bone loss and enhanced visceral adiposity. A polyclonal antibody that targets the beta-subunit of the pituitary hormone... 
WHITE | OBESITY | ENERGY-EXPENDITURE | BROWN-FAT | OSTEOCLAST FORMATION | MULTIDISCIPLINARY SCIENCES | FOLLICLE-STIMULATING-HORMONE | RECEPTOR | BONE MASS | MENOPAUSAL TRANSITION | OVARIECTOMIZED MICE | Obesity - drug therapy | Receptors, FSH - genetics | Adipose Tissue, White - metabolism | Diet, High-Fat - adverse effects | Follicle Stimulating Hormone, beta Subunit - antagonists & inhibitors | Male | Osteoporosis - drug therapy | Adipocytes - drug effects | Uncoupling Protein 1 - biosynthesis | Adipose Tissue - metabolism | Antibodies - immunology | Female | Receptors, FSH - metabolism | Adiposity - drug effects | Ovariectomy | Mitochondria - metabolism | Mitochondria - drug effects | Receptors, FSH - antagonists & inhibitors | Haploinsufficiency | Antibodies - pharmacology | Animals | Oxygen Consumption - drug effects | Adipocytes - metabolism | Obesity - prevention & control | Follicle Stimulating Hormone, beta Subunit - immunology | Adipose Tissue, Beige - drug effects | Mice | Thermogenesis - drug effects | Adipose Tissue - drug effects | Adipose Tissue, Beige - metabolism | Adipose Tissue, White - drug effects | Adipose tissues | Physiological aspects | Physiological research | Follicle-stimulating hormone | Thermogenesis | Research | Binding | Obesity | Immunoglobulins | Adipose tissue | Pituitary hormones | Body fat | Menopause | Blocking | Adipocytes | Hormones | Metabolism | Density | Osteoporosis | Mitochondria | Biomedical materials | Bone mass | Pituitary | Biocompatibility | Bone loss | Adipose tissue (brown)
Journal Article
Nature medicine, ISSN 1546-170X, 2017, Volume 23, Issue 12, pp. 1454 - 1465
Uncoupling protein 1 (UCP1) plays a central role in nonshivering thermogenesis in brown fat... 
MEDICINE, RESEARCH & EXPERIMENTAL | MALIGNANT HYPERTHERMIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | BROWN ADIPOSE-TISSUE | ENDOPLASMIC-RETICULUM STRESS | RYANODINE RECEPTOR GENE | RELEASE CHANNEL | MASS-SPECTROMETRY | ADAPTIVE NONSHIVERING THERMOGENESIS | CELL BIOLOGY | ENERGY-EXPENDITURE | UNCOUPLING PROTEIN-1 | FK506-BINDING PROTEIN FKBP12.6 | Animals, Newborn | Thermogenesis - genetics | Uncoupling Protein 1 - genetics | Calcium - metabolism | Humans | Mice, Inbred C57BL | Cells, Cultured | Signal Transduction - genetics | Mice, Knockout | Sarcoplasmic Reticulum Calcium-Transporting ATPases - physiology | Animals | Swine | HEK293 Cells | Glucose - metabolism | Mice | Calcium Signaling - genetics | Adipose Tissue, Beige - metabolism | Homeostasis - genetics | Uncoupling Protein 1 - physiology | Physiological aspects | Homeostasis | Brown adipose tissue | Genetic aspects | Research | Calcium ions | Cycles | Calcium | Body weight | Ryanodine receptors | Pyruvic acid | Body weight loss | Glucose | Adipocytes | Ca2+-transporting ATPase | Calcium signalling | Receptors | Uncoupling protein 1 | Rodents | Calcium homeostasis | Metabolism | Glucose tolerance | Energy balance | Thermogenesis | Glycolysis | Adrenergic receptors | Endoplasmic reticulum | ATP | Receptors (physiology) | Adenosine triphosphatase | Calcium (reticular) | Calcium cycling | SERCA2 | Non-canonical thermogenesis | Obesity | Beige fat | UCP1 | Diabetes
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2016, Volume 11, Issue 5, p. e0154310
Background Beige adipocytes comprise a unique thermogenic cell type in the white adipose tissue (WAT) of rodents and humans, and play a critical role in energy... 
ENERGY-BALANCE | THIAZOLIDINEDIONE | ADIPOCYTES | MULTIDISCIPLINARY SCIENCES | TISSUE | DISTINCT | PRDM16 | ACTIVATED-RECEPTOR-GAMMA | ROSIGLITAZONE | LIGAND | WEIGHT | Thermogenesis - genetics | Body Weight - drug effects | Hyperglycemia - complications | Male | Thiazolidinediones - chemistry | Obesity - genetics | Liver - drug effects | Intra-Abdominal Fat - drug effects | Thiazolidinediones - pharmacology | Uncoupling Protein 1 - genetics | Adiposity - drug effects | Obesity - complications | Liver - metabolism | Obesity - physiopathology | Intra-Abdominal Fat - metabolism | Adiposity - genetics | Adipose Tissue, Brown - pathology | Obesity - pathology | Triglycerides - metabolism | Gene Expression Regulation - drug effects | Animals | PPAR gamma - agonists | Adipose Tissue, Brown - drug effects | Adipose Tissue, Brown - metabolism | Mice | Intra-Abdominal Fat - pathology | Thermogenesis - drug effects | Blood Glucose - metabolism | Immunohistochemistry | CD40 antigen | Adipose tissue | Body fat | Liver | Genes | Homeostasis | Fuel consumption | Adipocytes | High fat diet | Recruitment | Proteins | Hyperglycemia | Rodents | Adipose tissue (brown) | Energy intake | Obesity | Alanine | Energy expenditure | Metabolism | Gene expression | Energy balance | Browning | Weight control | Thermogenesis | Morphology | Weight reduction | Alanine transaminase | Rosiglitazone | Ligands | Aspartate aminotransferase | Diabetes | Thiazolidinediones
Journal Article