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Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 11/2018, Volume 61, Issue 22, pp. 9976 - 9999
Due to the emergence of highly pathogenic and oseltamivir-resistant influenza viruses, there is an urgent need to develop new anti-influenza agents. Herein,... 
H5N1 | DESIGN | CHEMISTRY, MEDICINAL | REVERSE-TRANSCRIPTASE INHIBITORS | SMALL-MOLECULE INHIBITORS | POLYMERASE | DYNAMICS | NEURAMINIDASE-INHIBITOR | INFLUENZA-VIRUS | IDENTIFICATION | H1N1 | 4 acetamido 5 [(4 isopropylbenzyl)amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | Medical and Health Sciences | pharmacokinetic parameters | drug potency | drug structure | ethyl 4 acetamido 5 [[4 (benzo[b]thiophen 5 yl)benzyl]amino] 3 (pentan 3 yloxy) cyclohex 1 ene 1 carboxylate | oseltamivir derivative | MDCK cell line | virus sialidase | ethyl 4 acetamido 3 (pentan 3 yloxy) 5 [[4 (phenylthio)benzyl]amino]cyclohex 1 ene 1 carboxylate | 4 acetamido 5 [[4 (isobutylthio)benzyl]amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | 4 acetamido 3 (pentan 3 yloxy) 5 [(4 phenoxybenzyl)amino]cyclohex 1 ene 1 carboxylic acid | animal model | 4 acetamido 3 (pentan 3 yloxy) 5 [[4 (thiophen 2 yl thio)benzyl]amino]cyclohex 1 ene 1 carboxylic acid | Basic Medicine | ribavirin | rat | Influenza A virus (H5N6) | antivirus agent | 4 acetamido 5 [[4 (cyclopentyl)benzyl]amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | human cell | Influenza A virus (H5N2) | antiviral activity | animal experiment | 4 acetamido 5 [[4 (benzo[b]thiophen 2 yl)benzyl)amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | 4 acetamido 5 [[4 (cyclohexylthio)benzyl]amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | 4 acetamido 5 [[4 (sec butylthio)benzyl]amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | zanamivir | nonhuman | 4 acetamido 3 (pentan 3 yloxy) 5 [[4 (pentan 3 yloxy)benzyl]amino]cyclohex 1 ene 1 carboxylic acid | maximum concentration | diclofenac | 4 acetamido 3 (pentan 3 yloxy) 5 [[4 (phenylsulfonyl)benzyl]amino]cyclohex 1 ene 1 carboxylic acid | drug clearance | drug stability | 4 acetamido 5 [[3 (cyclopentyl)benzyl]amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | unclassified drug | molecular model | plasma concentration-time curve | Medicin och hälsovetenskap | metabolic stability | 4 acetamido 5 [[3 (sec butylthio)benzyl]amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | Article | drug synthesis | Influenza A virus (H5N1) | 4 acetamido 5 amino 3 (1 ethylpropoxy) 1 cyclohexene 1 carboxylic acid | 4 acetamido 5 [(4 benzylbenzyl)amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | propafenone | time to maximum plasma concentration | human | Influenza A virus (H5N8) | 4 acetamido 5 [(4 ethylbenzyl)amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | testosterone | 4 acetamido 5 [(4 methoxybenzyl)amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | bioassay | area under the curve | drug half life | Influenza A virus (H3N2) | 4 acetamido 5 [(4 benzoylbenzyl)amino] 3 (pentan 3 yloxy)cyclohex 1 ene 1 carboxylic acid | controlled study | Influenza A virus | Medicinska och farmaceutiska grundvetenskaper | oseltamivir | unindexed drug | 4 acetamido 3 (pentan 3 yloxy) 5 [[4 (phenylthio)benzyl]amino]cyclohex 1 ene 1 carboxylic acid
Journal Article
Journal Article
Phytochemistry, ISSN 0031-9422, 07/2014, Volume 103, pp. 114 - 122
Journal Article
Journal Article
Chemical Society reviews, ISSN 0306-0012, 02/2014, Volume 43, Issue 3, pp. 765 - 778
Heterogeneous photocatalysis has become a comprehensively studied area of research during the past three decades due to its practical interest in applications... 
Benzyl Alcohols - chemistry | Lignin - metabolism | Reactive Oxygen Species - chemistry | Reactive Oxygen Species - metabolism | Light | Lignin - chemistry | Nanostructures - chemistry | Benzyl Alcohols - metabolism | Biomass | Catalysis | Hydrogen - chemistry | Hydrogen - metabolism
Journal Article
Synthesis, ISSN 0039-7881, 02/2016, Volume 48, Issue 8, pp. 1122 - 1130
We describe the hitherto unknown use of N-Boc-protected hydrazine in the Ugi tetrazole reaction to access a library of highly substituted... 
tert butyl 2 [1 (1 benzyl 1h tetrazol 5 yl) 3 methylbutyl]hydrazine 1 carboxylic acid | tert butyl 2 [2 methyl 1 (1 phenethyl 1h tetrazol 5 yl)propyl]hydrazine 1 carboxylic acid | unclassified drug | proton transport | Ugi reaction | Ugi tetrazole reaction | tert butyl 2[1 (1 tert butyl 1h tetrazol 5 yl) 3 phenylpropyl]hydrazine 1 carboxylic acid | hydrazine | drug isolation | electrospray mass spectrometry | isocyanides | benzyl 4 [2 (tert butoxycarbonyl)hydrazino] 4[1 [2 (1h indol 3 yl)ethyl] 1h tetrazol 5 yl]piperidine 1 carboxylic acid | deprotection reaction | tert butyl 2 [1 (1 benzyl 1h tetrazol 5 yl) 3 phenylpropyl]hydrazine 1 carboxylic acid | tert butyl 2 [1 (1 benzyl 1h tetrazol 5 yl) 2 phenylethyl]hydrazine 1 carboxylic acid | tert butyl 2 [2 [1 (1 methoxy 4 methyl 1 oxopentan 2 yl) 1h tetrazol 5 yl]propan 2 yl]hydrazine 1 carboxylic acid | mass spectrometry | tert butyl 2 [1 (1 benzyl 1h tetrazol 5 yl) 2 methylpropyl]hydrazine 1 carboxylic acid | tert butyl 2 [cyclohexyl(1 cyclohexyl 1h tetrazol 5 yl)methyl]hydrazine 1 carboxylic acid | proton nuclear magnetic resonance | hydrazine derivative | drug screening | chemical reaction | supercritical fluid chromatography | tert butyl 2 [1 (1 benzyl 1h tetrazol 5 yl)(cyclohexyl)methyl]hydrazine 1 carboxylic acid | tert butyl 2 [1 (1 phenethyl 1h tetrazol 5 yl)cyclohexyl]hydrazine 1 carboxylic acid | article | carbon nuclear magnetic resonance | To be checked by Faculty | tert butyl 2 [3 methyl 1 (1 phenethyl 1h tetrazol 5 yl)butyl]hydrazine 1 carboxylic acid | one pot synthesis | tetrazoles | tert butyl 2 [1 chloro 2 [1 (4 chlorobenzyl) 1h tetrazol 5 yl]propan 2 yl]hydrazine 1 carboxylic acid | tert butyl 2 [2 [1 (4 chlorobenzyl) 1h tetrazol 5 yl]butan 2 yl]hydrazine 1 carboxylic acid | tert butyl 2 [1 [1 benzyl 4 [1 (4 chlorobenzyl) 1h tetrazol 5 yl]piperidin 4 yl]]hydrazine 1 carboxylic acid | tert butyl 2 [cyclohexyl (1 phenethyl 1h tetrazol 5 yl)methyl]hydrazine 1 carboxylic acid | multicomponent reaction | tert butyl 2 [2 chloro 1 [1 (4 chlorobenzyl) 1h tetrazol 5 yl]ethyl]hydrazine 1 carboxylic acid | paper | 3-COMPONENT REACTION | CHEMISTRY, ORGANIC | ALPHA-AMINO-ACIDS | MULTICOMPONENT REACTIONS | DIASTEREOSELECTIVE SYNTHESIS | CHEMISTRY | DIVERSITY | LEWIS-ACIDS | 4-COMPONENT CONDENSATION | EFFICIENT
Journal Article
Nature, ISSN 0028-0836, 11/2015, Volume 527, Issue 7579, pp. 477 - 483
At least 120 non-olfactory G-protein-coupled receptors in the human genome are 'orphans' for which endogenous ligands are unknown, and many have no selective... 
EXTRACELLULAR ACIDIFICATION | ACTIVATION | COMPLEX | OGR1 | PROTEIN-COUPLED RECEPTOR | MULTIDISCIPLINARY SCIENCES | CAMP ACCUMULATION | SMOOTH-MUSCLE-CELLS | EXPRESSION | CANCER | Anti-Anxiety Agents - metabolism | Lorazepam - pharmacology | Memory - drug effects | Receptors, G-Protein-Coupled - metabolism | Humans | Anti-Anxiety Agents - analysis | Male | Receptors, G-Protein-Coupled - agonists | Lorazepam - analysis | Benzyl Alcohols - pharmacology | HEK293 Cells | Anti-Anxiety Agents - chemistry | Female | Triazines - chemistry | Allosteric Regulation - drug effects | Benzyl Alcohols - chemistry | Triazines - metabolism | Triazines - pharmacology | Lorazepam - metabolism | Anti-Anxiety Agents - pharmacology | Models, Molecular | Drug Discovery | Mice, Knockout | Triazines - analysis | Fear | Animals | Receptors, G-Protein-Coupled - deficiency | Signal Transduction - drug effects | Benzyl Alcohols - analysis | Allosteric Site | Lorazepam - chemistry | Receptors, G-Protein-Coupled - antagonists & inhibitors | Conditioning, Classical | Benzyl Alcohols - metabolism | Ligands | Mice | Receptors, G-Protein-Coupled - chemistry | Physiological aspects | Cell receptors | Identification and classification | Ligands (Biochemistry) | Proteins | Yeast | Rodents | Physiology | Genomes | Kinases | proton-sensing | virtual screening | GPR68 | GPR65 | positive allosteric modulator (PAM) | functional selectivity | allosteric modulator
Journal Article
Journal Article
Journal of Catalysis, ISSN 0021-9517, 01/2018, Volume 357, pp. 147 - 153
[Display omitted] •Photocatalytic dehydrogenation of BA can be achieved using Co/CdS photocatalyst.•The system simultaneously produces H2 and benzaldehyde with... 
Dehydrogenation of benzyl alcohol | Hydrogen evolution | Photocatalysis | Benzyl alcohol oxidation | SYSTEM | SELECTIVE OXIDATION | COCATALYSTS | PHOTOCATALYTIC OXIDATION | CHEMISTRY, PHYSICAL | CORRESPONDING ALDEHYDES | GREEN | BENZYL ALCOHOL | ENGINEERING, CHEMICAL | TITANIUM-DIOXIDE | H-2 EVOLUTION | WATER | Nanoparticles | Cadmium | Sulfides | Hydrogen | Fine chemicals | Catalysis | Aldehydes
Journal Article
Chemical Communications: Chem Comm, ISSN 1359-7345, 11/2013, Volume 49, Issue 98, pp. 11524 - 11526
Well-dispersed small Au-Ag bimetallic nanoparticles (sub-3 nm) on one dimensional TiO sub(2) nanobelts were synthesized by a facile successive... 
Benzyl alcohol
Journal Article
Food Chemistry, ISSN 0308-8146, 09/2016, Volume 206, pp. 44 - 49
•Lipase-catalyzed synthesis of benzyl cinnamate was optimized in isooctane.•A 5-level-4-factor central composite design is successfully established.•The... 
Benzyl cinnamate | Response surface methodology | Lipase | Esterification | Optimization | ACID | GLYCEROL | CATALYZED SYNTHESIS | FOOD SCIENCE & TECHNOLOGY | ENZYMATIC-SYNTHESIS | NUTRITION & DIETETICS | ESTERS | CHEMISTRY, APPLIED | Cinnamates - metabolism | Temperature | Benzyl Compounds - metabolism | Lipase - metabolism | Benzyl Alcohol - metabolism
Journal Article
Journal Article
Advanced Synthesis & Catalysis, ISSN 1615-4150, 05/2012, Volume 354, Issue 7, pp. 1287 - 1292
An efficient metal‐free oxidative esterification of benzyl CH bonds was developed. Using tetrabutylammonium iodide as catalyst and tert‐butyl hydroperoxide as... 
tetrabutylammonium iodide | benzyl CH bond | protected amino acids | metal‐free catalyst | esterification | metal-free catalyst | benzyl C-H bond | ESTER | CATALYSIS | ACTIVATION | H BOND | ARENES | CHEMISTRY, ORGANIC | benzyl C?H bond | FUNCTIONALIZATION | CHEMISTRY, APPLIED | Synthesis | Iodides | Amino acids | Esters | Carboxylic acids | Bonding | Esterification | Radicals
Journal Article