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beta-1-integrin (324) 324
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NEW ENGLAND JOURNAL OF MEDICINE, ISSN 0028-4793, 04/2012, Volume 366, Issue 16, pp. 1508 - 1514
Integrin alpha(3) is a transmembrane integrin receptor subunit that mediates signals between the cells and their microenvironment. We identified three patients... 
MIGRATION | ORGANIZATION | MEDICINE, GENERAL & INTERNAL | EPIDERMIS | ALPHA-3-BETA-1 INTEGRIN | 3 BETA-1-INTEGRIN | EXPRESSION | CEREBRAL-CORTEX
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 05/2016, Volume 76, Issue 9, pp. 2513 - 2524
Tumor integrin beta 1 (ITGB1) contributes to primary tumor growth and metastasis, but its specific roles in extravasation have not yet been clearly elucidated.... 
ADHESION | BETA-1-INTEGRIN | ONCOLOGY | PROSTATE-CANCER CELLS | IN-VIVO | HUMAN BREAST-CANCER | ALPHA-3-BETA-1 | CARCINOMA | ENDOTHELIAL BARRIER | PROMOTES METASTASIS | MOUSE MODELS
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 02/2006, Volume 66, Issue 3, pp. 1526 - 1535
Current therapeutic approaches to cancer are designed to target molecules that contribute to malignant behavior but leave normal tissues intact. 01 integrin is... 
SIGNALING PATHWAYS | BETA-1-INTEGRIN | ONCOLOGY | DNA-DAMAGE | RESISTANCE | RECEPTOR | TUMOR-CELLS | EXPRESSION | CARCINOMA | CHEMOTHERAPY | MODULATION
Journal Article
KIDNEY INTERNATIONAL, ISSN 0085-2538, 09/2015, Volume 88, Issue 3, pp. 479 - 489
Integrin beta 1 and dipeptidyl peptidase (DPP)-4 play roles in endothelial cell biology. Vascular endothelial growth factor (VEGF)-A inhibits... 
CELLS | Flt1 | BETA-1-INTEGRIN | DIPEPTIDYL-PEPTIDASE-IV | Flk1 | smad3 | RENAL FIBROSIS | GROWTH-FACTOR-BETA | KIDNEY FIBROSIS | CD29 | MOUSE MODEL | UROLOGY & NEPHROLOGY | CD26 | MICE | STREPTOZOTOCIN | DIABETIC GLOMERULOPATHY | EndMT
Journal Article
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 01/2014, Volume 20, Issue 1
Purpose: Basal-like breast tumors are typically (ER/PR/HER2) triple-negative and are associated with a high incidence of brain metastases and poor clinical... 
ADHESION | ACTIVATION | GLIOBLASTOMA | BETA-1-INTEGRIN | TUMOR PROGRESSION | ONCOLOGY | ENDOTHELIAL-CELLS | CASPASE-3 | TRAIL-INDUCED APOPTOSIS | CARCINOMA | HEAT-SHOCK-PROTEIN
Journal Article
INTERNATIONAL JOURNAL OF CANCER, ISSN 0020-7136, 03/2016, Volume 138, Issue 5, pp. 1207 - 1219
Cancer-associated fibroblasts (CAFs) are reportedly involved in invasion and metastasis in several types of cancer, including gastric cancer (GC), through the... 
MIGRATION | CELLS | BETA-1-INTEGRIN | gastric cancer | integrin beta 1 | CXCR4 | CXCR4 CHEMOKINE RECEPTOR | CXCR4/CXCL12 AXIS | STEM | ADHESION | cancer-associated fibroblasts | CXCL12 | ONCOLOGY | GROWTH | STROMAL FIBROBLASTS | BINDING
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 03/2015, Volume 6
Angiogenic blood vessel growth requires several distinct but integrated cellular activities. Endothelial cell sprouting and proliferation lead to the expansion... 
VASCULAR DEVELOPMENT | MATRIX METALLOPROTEINASES | ADHESION | BETA-1-INTEGRIN | ENDOTHELIAL-CELL JUNCTIONS | MULTIDISCIPLINARY SCIENCES | DEPENDENT ENDOCYTOSIS | RETINAL ANGIOGENESIS | MICE | ADHERENS JUNCTIONS | TUMOR ANGIOGENESIS
Journal Article
by Li, C and Yang, Z and Du, Y and Tang, HD and Chen, J and Hu, DQ and Fan, ZS
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 08/2014, Volume 20, Issue 15, pp. 4001 - 4013
Purpose: To identify a novel biomarker for bladder cancer targeting therapy. Experimental Design: The human bladder cancer cell line T24 cells were used as... 
MIGRATION | PATHWAYS | BETA-1-INTEGRIN | ALPHABETA INTEGRIN | TUMOR PROGRESSION | ONCOLOGY | FOCAL ADHESION KINASE | CELL-LINES | EXPRESSION | ANTIGEN
Journal Article
by Hsu, YL and Wu, CY and Hung, JY and Lin, YS and Huang, MS and Kuo, PL
CARCINOGENESIS, ISSN 0143-3334, 06/2013, Volume 34, Issue 6, pp. 1370 - 1381
Lung cancer is a major cancer, leading in both incidence and mortality in the world, and metastasis underlies the majority of lung cancerrelated deaths.... 
INVASION | H-RAS | BETA-1-INTEGRIN | ONCOLOGY | NOTCH | RESISTANCE | RECEPTOR | FOCAL ADHESION KINASE | CELL MIGRATION | HUMAN BREAST-CANCER | BINDING
Journal Article
NATURE CELL BIOLOGY, ISSN 1465-7392, 05/2009, Volume 11, Issue 5, pp. 557 - U83
Gene expression reprogramming governs cellular processes such as proliferation, differentiation and cell migration through the complex and tightly regulated... 
BREAST-CANCER | MIGRATION | COACTIVATOR | BETA-1-INTEGRIN | METASTASIS | DIA1 | SRF ACTIVITY | INTEGRIN | DYNAMICS | MECHANISMS | CELL BIOLOGY
Journal Article
Molecular biology of the cell, ISSN 1059-1524, 01/2019, Volume 30, Issue 1, pp. 56 - 68
Neural stem cells (NSCs) are retained in the adult ventricular-subventricular zone (V-SVZ), a specialized neurogenic niche with a unique cellular architecture.... 
BETA-1-INTEGRIN | LAMININ | VASCULAR NICHE | INTEGRIN-BINDING | EXTRACELLULAR-MATRIX | PROLIFERATION | IDENTIFICATION | HEPARAN SULFATES | RADIAL GLIA | BRAIN | CELL BIOLOGY
Journal Article
PLOS ONE, ISSN 1932-6203, 10/2016, Volume 11, Issue 10
Functional cross-talk between Tie2 and Integrin signaling pathways is essential to coordinate endothelial cell adhesion and migration in response to the... 
CELL-CELL | MIGRATION | ACTIVATION | BETA-1-INTEGRIN | ANGIOGENESIS | ALPHABETA | MULTIDISCIPLINARY SCIENCES | CRYSTAL-STRUCTURES | GROWTH-FACTOR | ALPHA(V)BETA INTEGRIN | ALPHA-5-BETA-1 INTEGRIN
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 11/2009, Volume 69, Issue 22, pp. 8620 - 8628
Resistance to trastuzumab, the monoclonal antibody targeting human epidermal growth factor receptor 2 (HER-2), is a major concern for HER-2-positive metastatic... 
CELL LUNG-CANCER | SURVIVAL | BETA-1-INTEGRIN | VIVO | ONCOLOGY | HERCEPTIN | INTEGRIN | DOWN-REGULATION | RESISTANCE | FACTOR-I RECEPTOR | CONTRIBUTES
Journal Article
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 09/2012, Volume 18, Issue 17, pp. 4589 - 4599
Purpose: This study aimed to understand the prognostic value of integrin beta 1 expression in head and neck squamous cell carcinoma (HNSCC) and the mechanism... 
MIGRATION | ADHESION | MATRIX-METALLOPROTEINASE-2 | INVASION | FIBRONECTIN RECEPTOR | BETA-1-INTEGRIN | ONCOLOGY | CANCER METASTASIS | TUMOR | E-CADHERIN | EXPRESSION
Journal Article
DEVELOPMENT, ISSN 0950-1991, 11/2017, Volume 144, Issue 22, pp. 4148 - 4158
Kidney collecting system development requires integrin-dependent cell-extracellular matrix interactions. Integrins are heterodimeric transmembrane receptors... 
HEAD | ACTIVATION | DOMAIN | BETA-1-INTEGRIN | Tubules | DEVELOPMENTAL BIOLOGY | Kidney | Signaling | MAINTENANCE | COLLECTING-DUCT DEVELOPMENT | MICE | Nuclear magnetic resonance | NPXY MOTIFS | BINDING
Journal Article
JOURNAL OF CELLULAR PHYSIOLOGY, ISSN 0021-9541, 12/2017, Volume 232, Issue 12, pp. 3631 - 3640
Aberrant glycosylation changes on many glycoproteins are often related to cancer progression and metastasis. sp(2)-Iminosugar-type castanospermine analogues,... 
PHYSIOLOGY | calcium | BETA-1-INTEGRIN | MOLECULE | INTEGRIN | GLYCANS | breast cancer | glycosylation | Stim1 and Orai1 | N-GLYCOSYLATION | CELL BIOLOGY | INVASION | migration | ORAI1 | SENSOR STIM1 | EXPRESSION | PROGRESSION
Journal Article
JOURNAL OF THE NATIONAL CANCER INSTITUTE, ISSN 0027-8874, 06/2007, Volume 99, Issue 11, pp. 868 - 880
Background Integrins are the major adhesive molecules in mammalian cells. Each integrin subtype plays a unique role in cell differentiation and embryo... 
BETA-1-INTEGRIN | ONCOLOGY | INTEGRINS | PHOSPHATASE | GROWTH | MICE | GENE-EXPRESSION ANALYSIS | SUPPRESSION
Journal Article
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