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index medicus (161) 161
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cell biology (91) 91
beta-4 integrin (75) 75
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cytoplasmic domain (52) 52
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pyloric atresia (21) 21
immunohistochemistry (20) 20
integrin beta-4 (20) 20
migration (20) 20
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laminin (18) 18
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bullous pemphigoid antigen (16) 16
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cell line, tumor (15) 15
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cytoskeletal proteins (15) 15
gene expression (15) 15
integrin beta4 - metabolism (15) 15
integrins - metabolism (15) 15
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keratinocytes - metabolism (15) 15
molecular sequence data (15) 15
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Neoplasia, ISSN 1476-5586, 2012, Volume 14, Issue 8, pp. 678 - IN3
Journal Article
BRITISH JOURNAL OF DERMATOLOGY, ISSN 0007-0963, 07/2013, Volume 169, Issue 1, pp. 115 - 124
Background Integrin 64 is a transmembrane receptor and a key component of the hemidesmosome anchoring complex. It is involved in cell-matrix adhesion and... 
PYLORIC ATRESIA | CYTOPLASMIC DOMAIN | BETA-4 INTEGRIN | MISSENSE | GENE ITGB4 | NONSENSE | ITGB4 MUTATIONS | SKIN-DISEASE | OF-THE-LITERATURE | EXPRESSION | DERMATOLOGY
Journal Article
TRENDS IN PHARMACOLOGICAL SCIENCES, ISSN 0165-6147, 10/2007, Volume 28, Issue 10, pp. 506 - 511
The integrins play key roles in the signaling networks that drive pathological angiogenesis and tumor progression. Integrin beta 4 is a laminin receptor... 
CYTOPLASMIC DOMAIN | SIGNAL-TRANSDUCTION | CARCINOMA INVASION | ALPHA-6-BETA-4 INTEGRIN | PHOSPHOINOSITIDE 3-OH KINASE | ALPHABETA INTEGRIN | BETA-4 | BREAST CARCINOMAS | PHARMACOLOGY & PHARMACY | NF-KAPPA-B | EXPRESSION
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, pp. e87263 - e87263
The hemidesmosomal transmembrane component collagen XVII (ColXVII) plays an important role in the anchorage of the epidermis to the underlying basement... 
BETA-4 INTEGRIN | ALPHA-6-BETA-4 INTEGRIN | INVASION | FOCAL ADHESION | PHOSPHOINOSITIDE 3-OH KINASE | ALPHABETA INTEGRIN | HEMIDESMOSOMES | MULTIDISCIPLINARY SCIENCES | PROTEIN EXPRESSION | SQUAMOUS-CELL CARCINOMA | EPIDERMOLYSIS-BULLOSA | Focal Adhesion Kinase 1 - genetics | Cell Adhesion Molecules - genetics | Autoantigens - metabolism | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Phosphatidylinositol 3-Kinases - metabolism | Autoantigens - genetics | Integrin beta4 - metabolism | Cell Movement - physiology | Neuropeptides - genetics | Focal Adhesion Kinase 1 - metabolism | Skin Neoplasms - pathology | Neoplasm Invasiveness | Non-Fibrillar Collagens - genetics | Neuropeptides - metabolism | Keratinocytes - cytology | Integrin beta4 - genetics | Cell Adhesion Molecules - metabolism | Mice, Knockout | Skin Neoplasms - metabolism | Integrin beta1 - metabolism | Non-Fibrillar Collagens - metabolism | Phosphatidylinositol 3-Kinases - genetics | Animals | Pseudopodia - metabolism | Cell Adhesion - physiology | Keratinocytes - metabolism | Skin Neoplasms - genetics | Pseudopodia - genetics | Signal Transduction - physiology | Mice | Wound Healing - physiology | Integrin beta1 - genetics | rac1 GTP-Binding Protein - metabolism | rac1 GTP-Binding Protein - genetics | Squamous cell carcinoma | Laminin | Collagen | Integrins | Phosphorylation | Motility | Downstream effects | Kinases | Experiments | Cell adhesion & migration | Proteins | Signal transduction | Cell adhesion | Extracellular matrix | Antigens | Dermatology | Invasiveness | Wounds | Keratinocytes | Epidermis | Rac1 protein | Pseudopodia | Adhesion | 1-Phosphatidylinositol 3-kinase | Membrane proteins | Studies | Signaling | Stem cells | Mutation | Focal adhesion kinase | Cell migration | Index Medicus
Journal Article
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, ISSN 1044-1549, 04/2017, Volume 56, Issue 4, pp. 443 - 452
alpha(6)beta(4) integrin is localized in a unique punctate distribution at the cell-substratum interface along the leading front of single,... 
cytoskeleton | BIOCHEMISTRY & MOLECULAR BIOLOGY | KERATINOCYTES | FOCAL ADHESIONS | CELL BIOLOGY | cell motility | BETA-4 INTEGRIN | LUNG-CANCER | ALPHA-6-BETA-4 INTEGRIN | INVASION | HEMIDESMOSOMAL PROTEIN | RESPIRATORY SYSTEM | cell adhesion | directed motility | DYNAMICS | RAC ACTIVATION | EXPRESSION | matrix adhesions
Journal Article
JOURNAL OF CELLULAR PHYSIOLOGY, ISSN 0021-9541, 02/2012, Volume 227, Issue 2, pp. 474 - 478
Integrin heterodimers play diverse and important roles in physiological and pathological processes, such as cell adhesion, migration, proliferation,... 
CYTOPLASMIC DOMAIN | SIGNAL-TRANSDUCTION | DERIVATIVE INHIBITED APOPTOSIS | BETA-4 INTEGRIN | IN-VITRO | ALPHA-6-BETA-4 INTEGRIN | PHYSIOLOGY | ALPHABETA INTEGRIN | NF-KAPPA-B | BETA SUBUNIT | HISTORICAL-PERSPECTIVE | CELL BIOLOGY
Journal Article
Matrix Biology, ISSN 0945-053X, 2011, Volume 30, Issue 2, pp. 100 - 108
Collagen XVII (COL17) is a transmembrane glycoprotein that is expressed on the basal surface of basal epidermal keratinocytes. Previous observations have led... 
Extracellular matrix | Laminin 332 | Epidermolysis bullosa | Collagen XVII | Hemidesmosome | Dermal−epidermal junction | Dermal-epidermal junction | GENE DELIVERY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PASSIVE TRANSFER | EXTRACELLULAR DOMAIN | ALPHA-6 INTEGRIN | CELL BIOLOGY | INTEGRIN SUBUNIT | BETA-4 INTEGRIN | PEMPHIGOID AUTOANTIBODIES REACT | HERLITZ-DISEASE | JUNCTIONAL EPIDERMOLYSIS-BULLOSA | BASEMENT-MEMBRANE | RNA, Small Interfering - genetics | Cell Adhesion Molecules - genetics | Autoantigens - metabolism | Humans | Cell Adhesion Molecules - immunology | Integrin alpha3 - metabolism | Autoantigens - genetics | Gene Knockdown Techniques | Non-Fibrillar Collagens - immunology | Protein Binding - drug effects | Antibodies - immunology | Integrin beta1 - immunology | Extracellular Matrix Proteins - metabolism | Integrin alpha3 - genetics | Transduction, Genetic | Non-Fibrillar Collagens - genetics | Integrin alpha3 - immunology | Keratinocytes - cytology | Cell Adhesion - drug effects | Cell Adhesion Molecules - metabolism | Fibronectins - metabolism | Antibodies - pharmacology | Integrin beta1 - metabolism | Non-Fibrillar Collagens - metabolism | Collagen - metabolism | Cell Adhesion - physiology | Extracellular Matrix Proteins - immunology | Keratinocytes - metabolism | Autoantigens - immunology | K562 Cells | Cell Line, Tumor | Integrin beta1 - genetics | Protein Binding - physiology | Index Medicus | laminin 332 | epidermolysis bullosa | extracellular matrix | hemidesmosome | dermal-epidermal junction
Journal Article
EMBO JOURNAL, ISSN 0261-4189, 04/2009, Volume 28, Issue 8, pp. 1180 - 1190
The interaction between the integrin alpha 6 beta 4 and plectin is essential for the assembly and stability of hemidesmosomes, which are junctional adhesion... 
F-ACTIN | epidermolysis bullosa | MOBILIZATION | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | EPIDERMOLYSIS-BULLOSA | ACTIN-BINDING DOMAIN | hemidesmosome | CELL BIOLOGY | PYLORIC ATRESIA | BETA-4 INTEGRIN | plakin | cell adhesion | TANDEM PAIR | MUTATIONS | integrin | SUBUNIT
Journal Article
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 02/2008, Volume 14, Issue 4, pp. 1050 - 1058
Purpose: The beta 4 integrin has been implicated in functions associated with the genesis and progression of carcinomas based on data obtained from cell lines... 
CARCINOMA-CELLS | SURVIVAL | BETA-4 INTEGRIN | ALPHA-6-BETA-4 INTEGRIN | INVASION | MOLECULAR PORTRAITS | PROTEIN | ALPHABETA INTEGRIN | ONCOLOGY | CHEMOTACTIC MIGRATION | RECEPTOR
Journal Article
MOLECULAR AND CELLULAR BIOLOGY, ISSN 0270-7306, 07/2005, Volume 25, Issue 14, pp. 6090 - 6102
The alpha 6 beta 4 integrin-a laminin-5 receptor-mediates assembly of hemidesmosomes and recruitment of She and phosphoinositide 3-kinase through the unique... 
CYTOPLASMIC DOMAIN | CARCINOMA INVASION | PHOSPHOINOSITIDE 3-OH KINASE | ALPHABETA INTEGRIN | BETA-4 | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-ADHESION | C-JUN | HEMIDESMOSOME FORMATION | KERATINOCYTE MIGRATION | BASEMENT-MEMBRANE | CELL BIOLOGY
Journal Article
JOURNAL OF CELLULAR BIOCHEMISTRY, ISSN 0730-2312, 06/2014, Volume 115, Issue 6, pp. 1187 - 1195
We previously reported sphingosine 1-phosphate (S1P) and hepatocyte growth factor (HGF) augment endothelial cell (EC) barrier function and attenuate murine... 
BETA-4 | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOTHELIAL CELL | HEPATOCYTE GROWTH FACTOR | ACUTE LUNG INJURY | SPHINGOSINE-1-PHOSPHATE RECEPTORS | AGONISTS | SPHINGOSINE 1-PHOSPHATE | MURINE | CELL BIOLOGY | INTEGRINS | FTY720 | VASCULAR INTEGRITY | C-MET | GROWTH | RECEPTORS
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, ISSN 1040-0605, 08/2012, Volume 303, Issue 4, pp. L279 - L285
Chen W, Sammani S, Mitra S, Ma SF, Garcia JGN, Jacobson JR. Critical role for integrin-beta 4 in the attenuation of murine acute lung injury by simvastatin. Am... 
CYTOPLASMIC DOMAIN | endothelial cells | PHYSIOLOGY | BETA-4 | SEPSIS | integrins | INHIBITION | ALPHA-V-BETA-5 | STATIN THERAPY | RESPIRATORY SYSTEM | statins | INFLAMMATION | GENE-EXPRESSION | ALPHA-6-BETA-4 | DYSFUNCTION
Journal Article
CELLULAR AND MOLECULAR LIFE SCIENCES, ISSN 1420-682X, 07/2012, Volume 69, Issue 13, pp. 2233 - 2244
The laminin-binding integrin alpha 6 beta 4 plays key roles in both normal epithelial and endothelial cells and during tumor cell progression, metastasis, and... 
CELLS | CD151 | Palmitoylation | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | alpha 6 beta 4 | EPIDERMOLYSIS-BULLOSA | TETRASPANIN PROTEINS | CELL BIOLOGY | MEMBRANE INTERACTIONS | BETA-4 INTEGRIN | Integrin | CYSTEINE-RICH DOMAIN | DHHC3 | LAMININ-BINDING INTEGRINS | GABA(A) RECEPTORS
Journal Article
EMBO MOLECULAR MEDICINE, ISSN 1757-4676, 11/2012, Volume 4, Issue 11, pp. 1156 - 1175
Homing of colorectal cancer (CRC) cells to the liver is a non-random process driven by a crosstalk between tumour cells and components of the host tissue. Here... 
MIGRATION | MEDICINE, RESEARCH & EXPERIMENTAL | alpha integrin | angiopoietin-like 6 | MODEL | E-cadherin | microenvironment | BETA-4 INTEGRIN | ADHESION | ALPHA-6-BETA-4 INTEGRIN | INVASION | GENE-EXPRESSION | metastatic colorectal cancer | GROWTH-FACTOR | SELECTION | CARCINOMA
Journal Article
BMB Reports, ISSN 1976-6696, 2010, Volume 43, Issue 5, pp. 311 - 318
This review explored the mechanism of breast carcinoma progression by focusing on integrins and receptor tyrosine kinases (or growth factor receptors). While... 
ALPHABETA INTEGRIN | CANCER CELLS | Crosstalk | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEPATOCYTE GROWTH-FACTOR | Growth factor receptors | Survival | Invasion | Breast carcinoma progression | BETA-4 INTEGRIN | ALPHA-6-BETA-4 INTEGRIN | Integrin | INVASIVE GROWTH | EPITHELIAL-CELL MIGRATION | ENDOTHELIAL-CELLS | FIBRONECTIN RECEPTORS | ALPHA-5-BETA-1 INTEGRIN
Journal Article
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, ISSN 2059-7983, 04/2015, Volume 71, Issue 4, pp. 969 - 985
Journal Article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1422-0067, 10/2016, Volume 17, Issue 10, pp. 1540 - 1540
The alpha 6 beta 4 integrin is composed of the alpha 6 and beta 4 subunits that are encoded by the ITG alpha 6 and the ITG beta 4 genes, respectively. The... 
MIGRATION | alpha 6 beta 4 integrin | ACTIVATION | BETA-4 | BIOCHEMISTRY & MOLECULAR BIOLOGY | breast cancer | EPIDERMOLYSIS-BULLOSA | CHEMISTRY, MULTIDISCIPLINARY | INVASION | genetic variations | KOREAN POPULATION | ALPHA 6 | MUTATIONS | CARCINOMA | PROGRESSION
Journal Article
MOLECULAR CANCER THERAPEUTICS, ISSN 1535-7163, 05/2011, Volume 10, Issue 5, pp. 883 - 891
The functional interaction between integrin alpha 6 beta 4 and growth factor receptors has been implicated in key signaling pathways important for cancer cell... 
CARCINOMA-CELLS | BETA-4 INTEGRIN | SIGNALING PATHWAYS | ALPHABETA INTEGRIN | ONCOLOGY | HEMIDESMOSOMES | EPITHELIAL-CELL MIGRATION | LIPID RAFTS | GENE-EXPRESSION | KAPPA-B | CANCER
Journal Article
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