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1997, Lung biology in health and disease, ISBN 9780824794965, Volume 106, xvi, 443
Book
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, ISSN 1073-449X, 04/2013, Volume 187, Issue 7, pp. 690 - 696
beta(2)-Agonists are effective bronchodilators due primarily to their ability to relax airway smooth muscle (ASM). They exert their effects via their binding... 
COST-EFFECTIVENESS | INHALED BETA-ADRENOCEPTOR AGONIST | DOSE-RESPONSE | PHARMACOLOGICAL CHARACTERIZATION | COMBINATION THERAPY | LONG-ACTING BETA-AGONIST | asthma | OBSTRUCTIVE PULMONARY-DISEASE | beta-agonists | EMERGENCY-DEPARTMENT | RESPIRATORY SYSTEM | pharmacology | 24-H DURATION | guidelines | COPD | CRITICAL CARE MEDICINE
Journal Article
ChemMedChem, ISSN 1860-7179, 03/2012, Volume 7, Issue 3, pp. 483 - 494
Journal Article
CELL METABOLISM, ISSN 1550-4131, 01/2015, Volume 21, Issue 1, pp. 33 - 38
Increasing energy expenditure through activation of endogenous brown adipose tissue (BAT) is a potential approach to treat obesity and diabetes. The class of... 
SELECTIVE BETA-ADRENOCEPTOR AGONIST | THERMOGENESIS | ADRENOCEPTOR AGONIST | ENERGY-EXPENDITURE | COLD-EXPOSURE | METABOLISM | MIRABEGRON | ENDOCRINOLOGY & METABOLISM | DOUBLE-BLIND | FAT | ADULT HUMANS | CELL BIOLOGY
Journal Article
EUROPEAN UROLOGY, ISSN 0302-2838, 02/2013, Volume 63, Issue 2, pp. 283 - 295
Journal Article
BRITISH JOURNAL OF PHARMACOLOGY, ISSN 0007-1188, 07/2019, Volume 176, Issue 14, pp. 2539 - 2558
beta(3)-Adrenoceptor agonists have proven useful in the treatment of overactive bladder syndrome, but it is not known whether their efficacy during chronic... 
BETA-ADRENOCEPTOR AGONISTS | MOLECULAR CHARACTERIZATION | MESSENGER-RNA | PHARMACOLOGICAL CHARACTERIZATION | BETA-3-ADRENERGIC RECEPTOR EXPRESSION | DOWN-REGULATION | ALTERED CONTRACTILE RESPONSE | PHARMACOLOGY & PHARMACY | ADRENERGIC-RECEPTOR | BROWN ADIPOSE-TISSUE | UP-REGULATION
Journal Article
Neurourology and Urodynamics, ISSN 0733-2467, 08/2017, Volume 36, Issue 6, pp. 1511 - 1518
Aims To evaluate the effects of the beta‐3 adrenoceptor agonist, mirabegron in a mouse model of detrusor overactivity induced by obesity. Methods C57BL/6 male... 
detrusor | overactivity | cAMP | obesity | SELECTIVE BETA-ADRENOCEPTOR AGONIST | NON-VOIDING ACTIVITY | BROWN ADIPOSE-TISSUE | RAT URINARY-BLADDER | CONTRACTILE ACTIVITY | SMOOTH-MUSCLE | MESSENGER-RNA | IN-VIVO | OUTFLOW OBSTRUCTION | UROLOGY & NEPHROLOGY | PHARMACOLOGICAL PROFILE | Body Weight - drug effects | Male | Thiazoles - therapeutic use | Adrenergic beta-3 Receptor Agonists - pharmacology | Muscle, Smooth - drug effects | Urinary Bladder, Overactive - drug therapy | Urinary Bladder, Overactive - physiopathology | Urination - drug effects | Acetanilides - therapeutic use | Cyclic Nucleotide Phosphodiesterases, Type 4 - metabolism | Cyclic AMP - metabolism | Acetanilides - pharmacology | Urinary Bladder - metabolism | Mice, Inbred C57BL | Obesity - physiopathology | Urinary Bladder, Overactive - metabolism | Muscle, Smooth - metabolism | Obesity - metabolism | Carbachol - pharmacology | Adrenergic beta-3 Receptor Agonists - therapeutic use | Animals | Muscle Contraction - drug effects | Muscle, Smooth - physiopathology | Urinary Bladder - physiopathology | Mice, Obese | Urinary Bladder - drug effects | Mice | Thiazoles - pharmacology | Obesity | Carbachol | Analysis | Low density lipoproteins | Body weight | Cyclic adenylic acid | Adenylic acid | Lipoproteins (low density) | Adenosine | Fasting | Body fat | Intracellular levels | Contractility | Bladder | Cyclic AMP | Smooth muscle | Muscle contraction | Potassium chloride | High fat diet | Urinary bladder | Rodents | Protein expression | Adrenergic receptors | Urination | Lipoproteins (high density) | Phosphodiesterase
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 06/2017, Volume 60, Issue 11, pp. 4693 - 4713
By means of a formal structural hybridization of the antipsychotic drug aripiprazole and the heterocyclic catecholamine surrogates present in the... 
BETA-ADRENOCEPTOR AGONIST | QT PROLONGATION | DOPAMINE-D-2 RECEPTOR | CHEMISTRY, MEDICINAL | DOPA-INDUCED DYSKINESIA | RECEPTOR PARTIAL AGONISTS | FUNCTIONAL SELECTIVITY | G-PROTEIN | BINDING | DISCOVERY | PARKINSONS-DISEASE
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e71980
Nebivolol, a third generation beta-adrenoceptor (beta-AR) antagonist (beta-blocker), causes vasodilation by inducing nitric oxide (NO) production. The... 
RAT AORTA | CARVEDILOL | NITRIC-OXIDE PRODUCTION | EGF | MULTIDISCIPLINARY SCIENCES | ENDOTHELIAL-CELLS | PROTEIN-COUPLED RECEPTORS | BETA-ADRENOCEPTOR | EPIDERMAL GROWTH-FACTOR | BINDING | ADRENERGIC BLOCKERS | Ethanolamines - pharmacology | Phosphorylation | Adrenergic beta-1 Receptor Antagonists - pharmacology | Arrestins - genetics | Extracellular Signal-Regulated MAP Kinases - metabolism | G-Protein-Coupled Receptor Kinase 2 - metabolism | Arrestins - metabolism | MAP Kinase Signaling System | Receptor, Epidermal Growth Factor - metabolism | Benzopyrans - pharmacology | Fibroblasts - metabolism | Nebivolol | Cell Line | Receptors, Adrenergic, beta-2 - metabolism | Protein Transport | Animals | beta-Arrestin 2 | beta-Arrestin 1 | beta-Arrestins | Fibroblasts - drug effects | Mice | Protein Processing, Post-Translational | Carbazoles - pharmacology | Nitric Oxide - metabolism | Propanolamines - pharmacology | Health sciences | b-Adrenergic-receptor kinase | Smooth muscle | Arrestin | Myocytes | Isoproterenol | Vasodilation | Proteins | Epidermal growth factor | Rodents | Spots | Fibroblasts | Physiology | Propranolol | Heart diseases | Pharmaceutical sciences | Hypertension | Internal medicine | Epidermal growth factor receptors | Extracellular signal-regulated kinase | Cardiomyocytes | Pharmacology | siRNA | Embryo fibroblasts | Embryos | Medicine | G protein-coupled receptor kinase | Signaling | Hospitals | Nitric oxide | Coronary vessels | Internalization | Ligands | Adrenergic receptors
Journal Article
NEUROUROLOGY AND URODYNAMICS, ISSN 0733-2467, 09/2015, Volume 34, Issue 7, pp. 685 - 692
AimsTo assess the efficacy and safety of mirabegron 50mg once daily compared with placebo and the active control, tolterodine extended-release (ER) 4mg once... 
clinical trial | BETA-ADRENOCEPTOR AGONIST | METAANALYSIS | safety | phase III | PHASE-III | MUSCLE | UROLOGY & NEPHROLOGY | mirabegron | overactive bladder | randomized | efficacy | Clinical trials
Journal Article
Cellular Signalling, ISSN 0898-6568, 01/2018, Volume 42, pp. 54 - 66
Recruitment and activation of brite (or beige) adipocytes has been advocated as a potential avenue for manipulating whole-body energy expenditure. Despite... 
Brite adipocyte | UCP1 | Adipocyte | Glucose uptake | Mitochondria | β3-Adrenoceptor | Adrenoceptor | ACTIVATION | beta-Adrenoceptor | RECEPTOR | ADULT HUMANS | BROWN ADIPOSE-TISSUE | ADRENERGIC-STIMULATION | CELL BIOLOGY | WHITE FAT | BEIGE ADIPOCYTES | COLD-EXPOSURE | IN-VIVO | GENE-EXPRESSION | Adipocytes, White - cytology | Adipocytes, Beige - drug effects | Adipocytes, Brown - metabolism | Glucose Transporter Type 4 - metabolism | Glucose Transporter Type 1 - metabolism | Male | PPAR gamma - metabolism | Adipocytes, White - drug effects | Biological Transport | Receptors, Adrenergic, beta-3 - genetics | Thiazolidinediones - pharmacology | Cyclic AMP - metabolism | PPAR gamma - genetics | Uncoupling Protein 1 - genetics | Glucose Transporter Type 4 - genetics | Signal Transduction | Adipocytes, Beige - metabolism | Adipocytes, Brown - drug effects | Uncoupling Protein 1 - metabolism | Gene Expression Regulation | Adipocytes, Beige - cytology | Mitochondria - metabolism | Mitochondria - drug effects | Receptors, Adrenergic, beta-3 - metabolism | Organ Specificity | Hypoglycemic Agents - pharmacology | Animals | Glucose Transporter Type 1 - genetics | Oxygen Consumption - drug effects | PPAR gamma - agonists | Glucose - metabolism | Mice | Cyclic AMP - agonists | Primary Cell Culture | Adipocytes, Brown - cytology | Adipocytes, White - metabolism | Index Medicus | Biological Sciences | Naturvetenskap | Biologiska vetenskaper | Natural Sciences
Journal Article
BRITISH JOURNAL OF PHARMACOLOGY, ISSN 0007-1188, 07/2015, Volume 172, Issue 14, pp. 3537 - 3547
Background and Purpose(2)-adrenoceptor agonists are widely used in the management of obstructive airway diseases. Besides their bronchodilatory effect, several... 
FORMOTEROL | ADHESION | CYTOKINE PRODUCTION | INHALED BETA-ADRENOCEPTOR AGONIST | CONCISE GUIDE | PHARMACOLOGY | LIPOPOLYSACCHARIDE | PHARMACOLOGY & PHARMACY | RELEASE | EXPRESSION | SALMETEROL
Journal Article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, ISSN 0022-3565, 01/2013, Volume 344, Issue 1, pp. 218 - 230
Vilanterol trifenatate (vilanterol) is a novel, long-acting beta(2)-adrenoceptor (beta(2)-AR) agonist with 24 h activity. In this study, we describe the... 
BETA-ADRENOCEPTOR AGONISTS | BRONCHODILATOR | INDACATEROL | HIGH-AFFINITY | ASTHMA | PHARMACOLOGY & PHARMACY | ADRENERGIC-RECEPTORS | BINDING | SALMETEROL | COPD | BETA-AGONISTS
Journal Article
DIABETES, ISSN 0012-1797, 10/2018, Volume 67, Issue 10, pp. 2113 - 2125
beta 3-adrenergic receptor (AR) agonists are approved to treat only overactive bladder. However, rodent studies suggest that these drugs could have other... 
BETA-ADRENOCEPTOR AGONIST | OVERACTIVE BLADDER | ENERGY HOMEOSTASIS | ENDOCRINOLOGY & METABOLISM | MYOCARDIAL OXYGEN-CONSUMPTION | GENE-EXPRESSION | DOUBLE-BLIND | FUNCTIONAL-CHARACTERIZATION | ADULT HUMANS | COLD | BROWN FAT
Journal Article
Journal Article