X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (3888) 3888
Publication (822) 822
Book Review (600) 600
Book Chapter (81) 81
Conference Proceeding (77) 77
Reference (24) 24
Dissertation (7) 7
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (3156) 3156
humans (2311) 2311
animals (2155) 2155
beta-arrestins (2107) 2107
beta-arrestin (1752) 1752
arrestins - metabolism (1361) 1361
biochemistry & molecular biology (1148) 1148
signal transduction (1020) 1020
phosphorylation (999) 999
mice (813) 813
cell biology (807) 807
activation (704) 704
protein-coupled receptors (667) 667
cell line (664) 664
endocytosis (644) 644
beta-adrenergic receptor (599) 599
pharmacology & pharmacy (570) 570
arrestins - genetics (542) 542
internalization (533) 533
desensitization (532) 532
rats (503) 503
receptors, g-protein-coupled - metabolism (492) 492
beta-arrestin 2 (485) 485
arrestin (468) 468
ligands (467) 467
proteins (453) 453
male (445) 445
hek293 cells (441) 441
article (412) 412
protein binding (411) 411
neurosciences (366) 366
transfection (333) 333
expression (327) 327
signal transduction - physiology (326) 326
amino acid sequence (321) 321
cells (318) 318
cells, cultured (306) 306
trafficking (303) 303
signal transduction - drug effects (299) 299
β-arrestin (299) 299
molecular sequence data (297) 297
protein-coupled receptor (294) 294
multidisciplinary sciences (287) 287
receptors (282) 282
beta-arrestin 1 (273) 273
down-regulation (272) 272
g proteins (270) 270
female (262) 262
mice, knockout (262) 262
cyclic amp - metabolism (261) 261
arrestins - physiology (259) 259
cell membrane - metabolism (256) 256
kinases (244) 244
protein transport (243) 243
gtp-binding proteins - metabolism (241) 241
mutation (241) 241
crystal-structure (233) 233
gpcr (228) 228
binding (221) 221
cho cells (214) 214
models, biological (212) 212
research (208) 208
cell line, tumor (207) 207
mice, inbred c57bl (205) 205
receptor (204) 204
g protein-coupled receptor (200) 200
physiological aspects (198) 198
g protein-coupled receptors (196) 196
protein (190) 190
cos cells (186) 186
in-vivo (185) 185
cricetinae (184) 184
endocrinology & metabolism (179) 179
time factors (178) 178
signaling (173) 173
membrane proteins (170) 170
immunology (169) 169
dose-response relationship, drug (168) 168
kinetics (167) 167
analysis (166) 166
recombinant fusion proteins - metabolism (166) 166
endocytosis - physiology (164) 164
protein structure, tertiary (164) 164
functional selectivity (163) 163
cricetulus (160) 160
binding sites (156) 156
coupled receptors (156) 156
enzyme activation (155) 155
kinase (153) 153
physiology (153) 153
cyclic amp-dependent protein kinases - metabolism (152) 152
protein conformation (151) 151
arrestins - chemistry (150) 150
mitogen-activated protein kinase 1 - metabolism (150) 150
extracellular signal-regulated map kinases - metabolism (148) 148
beta-arrestins - metabolism (147) 147
blotting, western (147) 147
rats, sprague-dawley (147) 147
endocytosis - drug effects (146) 146
signal-transduction (146) 146
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (3889) 3889
Chinese (12) 12
French (10) 10
Japanese (7) 7
Korean (2) 2
Polish (2) 2
Russian (2) 2
Spanish (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


PAIN, ISSN 0304-3959, 09/2014, Volume 155, Issue 9, pp. 1829 - 1835
Opioids provide powerful analgesia but also efficacy-limiting adverse effects, including severe nausea, vomiting, and respiratory depression, by activating... 
Postoperative pain | RESPIRATORY DEPRESSION | Morphine | NEUROSCIENCES | DISCOVERY | CLINICAL NEUROLOGY | INHIBITION | LIGANDS | mu-Opioid receptor | BETA-ARRESTINS | PAIN MODELS | Clinical trial | ANESTHESIOLOGY | VENTILATORY RESPONSE | Biased ligand
Journal Article
NATURE, ISSN 0028-0836, 09/2011, Volume 477, Issue 7364, pp. 349 - U129
The human mind and body respond to stress(1), a state of perceived threat to homeostasis, by activating the sympathetic nervous system and secreting the... 
ACTIVATION | GENE | BETA-ARRESTINS | ADENYLYL-CYCLASE | MULTIDISCIPLINARY SCIENCES | NUCLEAR EXPORT SIGNAL | SHORT-INTERFERING RNAS | N-DOMAIN | RECEPTOR | MAMMALIAN-CELLS | EXPRESSION
Journal Article
PLOS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4
Under normal conditions the brain maintains a delicate balance between inputs of reward seeking controlled by neurons containing the D-1-like family of... 
D2 RECEPTORS | SIGMA-RECEPTORS | TRANSPORTER | BETA-ARRESTINS | MULTIDISCIPLINARY SCIENCES | STRIATOPALLIDAL NEURONS | IN-VIVO | GENE-EXPRESSION | MICE | D1 RECEPTOR | ADDICTION
Journal Article
Circulation, ISSN 0009-7322, 03/2019, Volume 139, Issue 13, pp. 1629 - 1642
BACKGROUND:Receptor signaling is central to vascular endothelial function and is dysregulated in vascular diseases such as atherosclerosis and pulmonary... 
hypertension, pulmonary | receptors, vascular endothelial growth factor | beta-arrestins | GTP-binding proteins
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2018, Volume 115, Issue 12, pp. 2856 - 2858
Journal Article
Journal Article
PLOS ONE, ISSN 1932-6203, 01/2012, Volume 7, Issue 1
The discovery that drugs targeting a single G protein-coupled receptor (GPCR) can differentially modulate distinct subsets of the receptor signaling repertoire... 
LABEL-FREE | ACTIVATION | EFFICACY | BETA-ARRESTINS | PHARMACOLOGY | MULTIDISCIPLINARY SCIENCES | DRUG DISCOVERY | PROTEIN-COUPLED RECEPTORS | FUNCTIONAL SELECTIVITY | TECHNOLOGY | LIVING CELLS
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 02/2011, Volume 336, Issue 2, pp. 296 - 302
Journal Article
MOLECULAR PHARMACOLOGY, ISSN 0026-895X, 11/2017, Volume 92, Issue 5, pp. 613 - 626
Traditionally, G protein-coupled receptor antagonists are classified as competitive or noncompetitive and surmountable or insurmountable based on functional... 
PATHWAYS | 7-TRANSMEMBRANE RECEPTORS | ACTIVATION | BIASED AGONISM | EFFICACY | BETA-ARRESTINS | PROTEIN-COUPLED RECEPTORS | ADENOSINE RECEPTOR | PHARMACOLOGY & PHARMACY | DISCOVERY | CONFORMATIONS
Journal Article
Science, ISSN 0036-8075, 5/2013, Volume 340, Issue 6132, pp. 615 - 619
Journal Article
CELL, ISSN 0092-8674, 12/2010, Volume 143, Issue 7, pp. 1149 - 1160
Following pilus-mediated adhesion to human brain endothelial cells, meningococcus (N. meningitidis), the bacterium causing cerebrospinal meningitis, initiates... 
ADHESION | TYROSINE-KINASE | ACTIVATION | EPITHELIAL-CELLS | BETA-ARRESTINS | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEISSERIA-MENINGITIDIS | BARRIER | PROTEIN-COUPLED RECEPTORS | IV PILI | ARRESTIN-DEPENDENT ENDOCYTOSIS | CELL BIOLOGY
Journal Article
MOLECULAR PHARMACOLOGY, ISSN 0026-895X, 08/2012, Volume 82, Issue 2, pp. 178 - 188
Previously we correlated the efficacy for G protein activation with that for arrestin recruitment for a number of agonists at the mu-opioid receptor (MOPr)... 
7-TRANSMEMBRANE RECEPTORS | INTERNALIZATION | EFFICACY | MORPHINE | PHOSPHORYLATION | BETA-ARRESTINS | DESENSITIZATION | TOLERANCE | TRAFFICKING | PHARMACOLOGY & PHARMACY | LOCUS-COERULEUS NEURONS
Journal Article
Hypertension, ISSN 0194-911X, 11/2017, Volume 70, Issue 5, pp. 972 - 981
Heart failure is the leading cause of death in the Western world, and new and innovative treatments are needed. The GPCR (G protein-coupled receptor) adapter... 
heart failure | apoptosis | sumoylation | arrestins | myocardial infarction | SYSTEM | CELLS | MYOCYTES | SERCA2A | INHIBITION | BETA-ARRESTINS | IN-VIVO | PERIPHERAL VASCULAR DISEASE | EXPRESSION | RECEPTOR-BINDING | Index Medicus
Journal Article
Biochemical Journal, ISSN 0264-6021, 02/2019, Volume 476, Issue 3, pp. 513 - 533
Following nutrient ingestion, glucagon-like peptide 1 (GLP-1) is secreted from intestinal L-cells and mediates anti-diabetic effects, most notably stimulating... 
DIFFERENTIAL TRAFFICKING | INTERNALIZATION | PROTEIN | PHOSPHORYLATION | BETA-ARRESTINS | GLUCOSE | DESENSITIZATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | INSULIN-SECRETION | GLP-1 RECEPTOR | SUBSTANCE-P
Journal Article
JOURNAL OF NEUROSCIENCE, ISSN 0270-6474, 03/2014, Volume 34, Issue 10, pp. 3545 - 3558
The general effects of cocaine are not well understood at the molecular level. What is known is that the dopamine D-1 receptor plays an important role. Here we... 
HETEROMERS | ACTIVATION | STRIATAL SLICES | RAT | BETA-ARRESTINS | DISEASE | SIGMA-1 RECEPTORS | MECHANISMS | PROXIMITY LIGATION ASSAY | AGONISTS | NEUROSCIENCES
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2017, Volume 114, Issue 10, pp. 2562 - 2567
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.