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Journal of the American Chemical Society, ISSN 0002-7863, 01/2014, Volume 136, Issue 1, pp. 506 - 512
Copper amine oxidases are a family of enzymes with quinone cofactors that oxidize primary amines to aldehydes. The native mechanism proceeds via an... 
COENZYME PQQ | BOVINE PLASMA AMINE | BETA-CARBOLINE ALKALOIDS | ELECTRON-TRANSFER | MECHANISM | IMINES | INDOLE ALKALOIDS | TRANSITION-METALS | CHEMISTRY, MULTIDISCIPLINARY | CHEMICAL-PROPERTIES | MOLECULAR-OXYGEN
Journal Article
TETRAHEDRON, ISSN 0040-4020, 11/2018, Volume 74, Issue 48, pp. 6873 - 6877
In the frame of substrate specificity, CAL-B-catalysed asymmetric N-alkoxycarbonylations of 1-substituted tetrahydro-beta-carbolines (Me, Et, Pr, iPr) have... 
ACYLATION | Substrate specificity | CHEMISTRY, ORGANIC | beta-carboline | Kinetic resolution | CAL-B | TETRAHYDRO-BETA-CARBOLINE | STRICTOSIDINE | ALKALOIDS
Journal Article
Organic Letters, ISSN 1523-7060, 12/2016, Volume 18, Issue 23, pp. 6192 - 6195
The copper-catalyzed asymmetric propargylation of cyclic aldimines is reported. The influence of the imine trimer to inhibit the reaction was identified, and... 
ENANTIOSELECTIVE CARBONYL PROPARGYLATION | KETONES | AMINES | IMINES | ISOQUINOLINE ALKALOIDS | CHEMISTRY, ORGANIC | TRANSFER HYDROGENATION | ALDEHYDES | HYDROAMINATION | TETRAHYDRO-BETA-CARBOLINE | EFFICIENT
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 01/2019, Volume 17, Issue 4, pp. 835 - 844
An AcOH-mediated concise, atom-economical and environmentally sustainable tandem strategy has been formulated to access highly fluorescent (Phi(F) up to 40%)... 
INHIBITION | ANTICANCER | CONVERSION | COMPLEXES | BIOLOGICAL EVALUATION | SECONDARY | CHEMISTRY, ORGANIC | BETA-CARBOLINE | DISCOVERY | SCAFFOLD | ALKALOIDS
Journal Article
HISTOLOGY AND HISTOPATHOLOGY, ISSN 0213-3911, 10/2019, Volume 34, Issue 10, pp. 1185 - 1193
This experiment evaluated the effects of harmine against nicotine-induced damage to the liver of mice. Nicotine is a major toxic component of cigarette smoke... 
HARMALA | BETA-CARBOLINE ALKALOIDS | MORPHINE | Liver | INJURY | PATHOLOGY | Harmine | GENISTEIN | STRESS | Nicotine | CELL BIOLOGY
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 08/2017, Volume 82, Issue 15, pp. 7695 - 7707
Indolylmethanols have emerged as versatile reactants in catalytic asymmetric reactions because of the facile generation of reactive intermediates from these... 
ENANTIOSELECTIVE SYNTHESIS | PHOSPHORIC-ACID | INDOL-2-YL CARBINOLS | DIELS-ALDER REACTION | ALPHA-ALKYLATION | CHEMISTRY, ORGANIC | INDOLE-DERIVATIVES | BRONSTED-ACID CATALYSIS | FRIEDEL-CRAFTS REACTION | TETRAHYDRO-BETA-CARBOLINE | FLUORENE DERIVATIVES | Chemical reactions | Usage | Chemical properties | Catalysis | Indole
Journal Article
Scientific Reports, ISSN 2045-2322, 02/2017, Volume 7, Issue 1, p. 42811
A simple strategy is proposed to design and develop an intelligent device based on dual channel ion responsive spectral properties of a commercially available... 
CU2 | FLUORESCENCE | LOGIC GATES | MULTIDISCIPLINARY SCIENCES | ENCODER-DECODER | BETA-CARBOLINE | KEYPAD LOCK SYSTEM
Journal Article
NEW JOURNAL OF CHEMISTRY, ISSN 1144-0546, 01/2019, Volume 43, Issue 1, pp. 93 - 102
An efficient protocol has been developed for one-pot synthesis of biologically interesting -carboline substituted 1,3,4-oxadiazoles via an I-2-assisted... 
DESIGN | HYDRAZIDES | ONE-POT SYNTHESIS | ANNULATION | INHIBITORS | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | ANTIMALARIAL BETA-CARBOLINE | ALKALOIDS
Journal Article
Tetrahedron: Asymmetry, ISSN 0957-4166, 12/2017, Volume 28, Issue 12, pp. 1829 - 1833
Racemic 1-methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline and 1-methyl-1,2,3,4-tetrahydro-ß-carboline were resolved through lipase-catalysed asymmetric... 
ASYMMETRIC-SYNTHESIS | TETRAHYDROISOQUINOLINES | ENANTIOSELECTIVE SYNTHESIS | AMINES | CHEMISTRY, PHYSICAL | DEPROTECTION | TETRAHYDRO-BETA-CARBOLINE | DERIVATIVES
Journal Article
Tetrahedron, ISSN 0040-4020, 08/2017, Volume 73, Issue 31, pp. 4545 - 4548
Tiruchanduramine was prepared using a convergent strategy with the longest linear sequence being eight steps. Synthetic , displayed a broader range of... 
Glycosidase inhibition | Guanidines | Synoicum macroglossum | Tiruchanduramine | β-carboline | CHEMISTRY, ORGANIC | beta-carboline | ALKALOIDS | Guanidine
Journal Article
by Yan, L and Wang, DL and Qian, JH
HETEROCYCLES, ISSN 0385-5414, 02/2017, Volume 94, Issue 2, pp. 334 - 341
An efficient tandem process for the synthesis of pyridoimidazo-fused beta-carbolines: pyrido[2",1":2'3'] imidazo [4',5':2,3]pyrido[4,5-b]indole, is described.... 
CHEMISTRY, ORGANIC | BETA-CARBOLINE ALKALOIDS | DERIVATIVES | MULTICOMPONENT REACTION
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 03/2019, Volume 60, Issue 11, pp. 800 - 804
Organic base DBN has been identified as an efficient reagent for promoting the dehydrogenative/decarboxylative aromatization of tetrahydro-β-carbolines under... 
Aromatization | β-Carboline | Dehydrogenation | Decarboxylation | NORHARMANE | DESIGN | POT DECARBOXYLATIVE AROMATIZATION | HARMANE | CHEMISTRY, ORGANIC | beta-Carboline | DERIVATIVES | EUDISTOMIN U | N-HETEROCYCLES
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 07/2017, Volume 58, Issue 28, pp. 2747 - 2750
The oxidation of tetrahydro-β-carbolines to β-carbolines using silver carbonate was developed as an alternative to current methods. The oxidation is extremely... 
Aromatization | Oxidation | β-Carboline | Silver carbonate | CHEMISTRY, ORGANIC | beta-Carboline | ANTIMALARIAL | DISCOVERY
Journal Article
Journal of Molecular Structure, ISSN 0022-2860, 01/2020, Volume 1200, p. 127070
In this study, a new tetrahydro-β-carboline derivative, 2-benzoyl-6-methoxy-9-methyl-1-phenyl-1,2,3,4-tetrahydro-β-carboline has been synthesized through a... 
Tetrahydro-β-carboline | Cytotoxicity | Acetylcholinesterase | ADMET | Single crystal | Molecular docking | DESIGN | ALZHEIMERS-DISEASE | CHEMISTRY, PHYSICAL | Tetrahydro-beta-carboline | DERIVATIVES | PREDICTION
Journal Article
Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 10/2018, Volume 28, Issue 18, pp. 3123 - 3128
A series of canthin-6-one analogues were designed and synthesized in order to study their antibacterial activity and structure–activity relationships. Compound... 
Antibacterial activity | Synthesis | Structure–activity relationships | Canthin-6-one | Mechanism | CHEMISTRY, MEDICINAL | ACID | CHEMISTRY, ORGANIC | OPTIMIZATION | Structure-activity relationships | BETA-CARBOLINE | DISCOVERY
Journal Article
by Li, N and Liu, D and Dai, JK and Wang, JY and Wang, JR
MOLECULES, ISSN 1420-3049, 04/2019, Volume 24, Issue 8, p. 1553
Background: Based on our previous work, we found that 10-methoxycanthin-6-one displayed potential antibacterial activity and quaternization was an available... 
10-methoxycanthin-6-one | DESIGN | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG DISCOVERY | LEADS | SARs | antibacterial | BETA-CARBOLINE | quaternization | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 10/2019, Volume 243, p. 112096
The plant is used in traditional medicine to treat lung inflammation for a long time. However, the anti-pulmonary fibrosis effect and its corresponding... 
β-carboline alkaloids | Arenaria kansuensis | Pulmonary fibrosis | NF-kb/p65 | EMT | PATHWAYS | CHEMISTRY, MEDICINAL | INTEGRATIVE & COMPLEMENTARY MEDICINE | beta-carboline alkaloids | PHARMACOLOGY & PHARMACY | PLANT SCIENCES
Journal Article
Neuroscience Letters, ISSN 0304-3940, 10/2019, Volume 711, p. 134437
Parkinson’s disease (PD) is characterised pathologically by degeneration of the dopaminergic (DA) neurones of the substantia nigra pars compacta (SNpc) and the... 
Trichloroethylene | α-Synuclein | TaClo | Neurodegeneration | Parkinson’s disease | Parkinson's disease | MOUSE | PATHOLOGY | NEUROSCIENCES | MUTATION | NEUROTOXIN 1-TRICHLOROMETHYL-1,2,3,4-TETRAHYDRO-BETA-CARBOLINE | MPTP | DEFICITS | alpha-Synuclein | PARKINSONS-DISEASE
Journal Article
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