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Organic Letters, ISSN 1523-7060, 09/2018, Volume 20, Issue 17, pp. 5431 - 5434
A practical synthesis of chiral tryptamines from simple, unprotected indoles has been developed. Indole nucleophiles prepared with MeMgCl in the presence of... 
BETA-CARBOLINES | POTENT | RECEPTOR AGONISTS | SPIROINDOLONES | CHEMISTRY, ORGANIC | MALARIA | DERIVATIVES
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 07/2014, Volume 136, Issue 30, pp. 10807 - 10813
meta-C–H olefination, arylation, and acetoxylation of indolines have been developed using nitrile-containing templates. The combination of a monoprotected... 
TETRAHYDRO-BETA-CARBOLINES | FUNCTIONALIZATION | ROOM-TEMPERATURE | ACTIVATION | NATURAL-PRODUCTS | ALKYLATION | ELECTRON-DEFICIENT ARENES | CARBON-HYDROGEN BONDS | CONFORMATION | CHEMISTRY, MULTIDISCIPLINARY | ALKALOIDS | Palladium | Chemical properties | Hydrogen | Carbon compounds | Olefins
Journal Article
Chemical Society Reviews, ISSN 0306-0012, 2007, Volume 36, Issue 7, pp. 1095 - 1108
For a long time multi-component syntheses of heterocycles have undeniably been a domain of classical carbonyl condensation chemistry. However, the advent of... 
TETRAHYDRO-BETA-CARBOLINES | ORGANIC-SYNTHESIS | 3-COMPONENT SYNTHESIS | DOMINO REACTIONS | ACID-CHLORIDES | ONE-POT SYNTHESIS | ADDITION-CYCLOCONDENSATION SEQUENCES | FISCHER INDOLE SYNTHESIS | STEREOSELECTIVE-SYNTHESIS | CHEMISTRY, MULTIDISCIPLINARY | COUPLING APPROACH
Journal Article
ORGANIC LETTERS, ISSN 1523-7060, 09/2019, Volume 21, Issue 17, pp. 6658 - 6662
A mild, reductive spirocyclization of indole-linked amides and lactams for the efficient and selective synthesis of aza-spirocyclic indoline products is... 
TETRAHYDRO-BETA-CARBOLINES | REDUCTION | CONSTRUCTION | CHEMISTRY, ORGANIC | ASPIDOSPERMA | STEREOSELECTIVE-SYNTHESIS | BINDING | CYCLIZATION | ALKALOIDS
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 12/2017, Volume 82, Issue 24, pp. 13671 - 13677
An expeditious one-step synthesis of the imidazopyridoindole scaffold was achieved through the C–H oxidation/two-fold cyclization reaction of methyl ketone and... 
BENZYLIC OXIDATION | FUNCTIONALIZATION | BETA-CARBOLINES | AMINATION | ONE-POT SYNTHESIS | CONSTRUCTION | CHEMISTRY, ORGANIC | CASCADE | SEROTONIN | AROMATIZATION | DERIVATIVES
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 12/2009, Volume 48, Issue 51, pp. 9608 - 9644
Journal Article
Organic Letters, ISSN 1523-7060, 06/2018, Volume 20, Issue 11, pp. 3220 - 3224
The combination of a Pd(0) complex with benzoic acid converts propargylic tryptamines to the corresponding tetrahydro-β-carbolines. The method uses unprotected... 
TETRAHYDRO-BETA-CARBOLINES | PICTET-SPENGLER REACTION | ENANTIOSELECTIVE SYNTHESIS | AMINES | ALLYLATION | ALLYLIC ALKYLATION | CHEMISTRY, ORGANIC | ALKYNES | C-H ACTIVATION | INDOLES | CYCLIZATION
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 02/2007, Volume 13, Issue 5, pp. 1358 - 1373
Indoles react intramolecularly with alkynes in the presence of gold catalysts to give from six‐ to eight‐membered‐ring annulated compounds. The cationic AuI... 
gold | allenes | indoles | homogeneous catalysis | cyclization | alkynes | Gold | Allenes | Indoles | Cyclization | Homogeneous catalysis | Alkynes | PHENOL SYNTHESIS | PROPARGYLIC ESTERS | BETA-CARBOLINES | H BOND FUNCTIONALIZATION | CHEMISTRY, MULTIDISCIPLINARY | 3-SUBSTITUTED INDOLES | ELECTROPHILIC SUBSTITUTION | CYCLOISOMERIZATION REACTION | METHYL KETONES | HYDROARYLATION
Journal Article
Chemical Reviews, ISSN 0009-2665, 12/2017, Volume 117, Issue 23, pp. 13757 - 13809
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 11/2007, Volume 129, Issue 44, pp. 13404 - 13405
Journal Article
Organic Letters, ISSN 1523-7060, 12/2018, Volume 20, Issue 23, pp. 7470 - 7473
A Pd­(OAc)2-catalyzed asymmetric cyclization of 2-aminoaryl alkynones involving an intramolecular trans-aminopalladation of alkyne and 1,2-addition to the... 
TETRAHYDRO-BETA-CARBOLINES | ACID | PICTET-SPENGLER REACTION | STEREOSELECTIVITY | BENZOQUINONE | CONSTRUCTION | CHEMISTRY, ORGANIC | TRANSFER HYDROGENATION | ELIMINATION | DERIVATIVES | CYCLIC IMINES
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 02/2006, Volume 45, Issue 7, pp. 1105 - 1109
Going for gold: Cationic gold(I) complexes favor formation of six‐ and seven‐membered rings by 6‐endo‐dig, 6‐exo‐dig, and 7‐exo‐dig cyclizations of alkynyl... 
gold | allenes | indoles | cyclization | alkynes | Gold | Allenes | Indoles | Cyclization | Alkynes | BETA-CARBOLINES | COMPLEXES | PLATINUM | H BOND FUNCTIONALIZATION | ASPERGILLUS-USTUS | CHEMISTRY, MULTIDISCIPLINARY | 3-SUBSTITUTED INDOLES | ELECTROPHILIC SUBSTITUTION | CYCLOISOMERIZATION REACTION | HYDROARYLATION
Journal Article