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by Wang, ZK and Yang, Y and Hu, T and Zhu, ZZ and Zhou, Y and Huang, Q and Li, LP and Deng, L and Chen, ZL and Chen, WL and Deng, QF and Wang, SL
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, ISSN 1940-5901, 2019, Volume 12, Issue 4, pp. 4280 - 4286
Background: There is a lack of clinical evidence on the relationship between islet beta-cell dysfunction with the prognosis and the major organ dysfunction in... 
MORTALITY | MEDICINE, RESEARCH & EXPERIMENTAL | CYTOKINES | Trauma | Islet beta-cell dysfunction | prognosis | FAILURE | INSULIN | BURN | multiple organ dysfunction | HYPERGLYCEMIA | MODS | inflammation
Journal Article
Circulation Research, ISSN 0009-7330, 02/2012, Volume 110, Issue 4, pp. 598 - 608
RATIONALE:Hyperamylinemia is common in patients with obesity and insulin resistance, coincides with hyperinsulinemia, and results in amyloid deposition. Amylin... 
hyperamylinemia | UCD-T2DM rat | calcium | diabetic cardiomyopathy | hyperinsulinemia | HIP rat | CARDIAC & CARDIOVASCULAR SYSTEMS | IMPAIRED GLUCOSE-TOLERANCE | ISLET-AMYLOID POLYPEPTIDE | INSULIN-RESISTANCE | VENTRICULAR EXPRESSION | DISEASE | PANCREATIC BETA-CELLS | PERIPHERAL VASCULAR DISEASE | NONISCHEMIC HEART-FAILURE | HEMATOLOGY | UCD-T2DM RATS | LIGHT-CHAINS | Immunohistochemistry | Prediabetic State - metabolism | Diabetic Cardiomyopathies - metabolism | Diabetic Cardiomyopathies - etiology | Ventricular Function, Left | Humans | Middle Aged | Heart Failure - physiopathology | Cardiomegaly - etiology | Male | Islet Amyloid Polypeptide - genetics | Diabetes Mellitus, Type 2 - metabolism | Diabetic Cardiomyopathies - physiopathology | Young Adult | Ventricular Remodeling | Myocardium - metabolism | Ultrasonography | Adult | Female | Heart Failure - diagnostic imaging | Heart Failure - etiology | Calcium Signaling | Diabetes Mellitus, Type 2 - complications | Disease Models, Animal | Diabetic Cardiomyopathies - diagnostic imaging | Rats, Transgenic | Obesity - complications | NFATC Transcription Factors - metabolism | Cardiomegaly - physiopathology | Islet Amyloid Polypeptide - metabolism | Rats | Ventricular Dysfunction, Left - etiology | Histone Deacetylases - metabolism | Myocardium - pathology | Heart Failure - metabolism | Prediabetic State - complications | Rats, Sprague-Dawley | Blotting, Western | Ventricular Dysfunction, Left - physiopathology | Obesity - metabolism | Ventricular Dysfunction, Left - metabolism | Animals | Aged | Ventricular Pressure | Cardiomegaly - metabolism | Index Medicus
Journal Article
Journal Article
The Journal of Nutritional Biochemistry, ISSN 0955-2863, 07/2012, Volume 23, Issue 7, pp. 716 - 724
Journal Article
Clinical Endocrinology, ISSN 0300-0664, 12/2018, Volume 89, Issue 6, pp. 779 - 788
Objective To investigate both independent and combined effects of insulin resistance and beta-cell dysfunction on cardio-metabolic abnormalities in polycystic... 
beta‐cell dysfunction | metabolic Syndrome | insulin secretion | insulin resistance | polycystic ovary syndrome | beta-cell dysfunction | ETHNIC-DIFFERENCES | DEFECTS | SENSITIVITY | PREVALENCE | FAILURE | GLUCOSE | ENDOCRINOLOGY & METABOLISM | HEALTH | Polycystic ovary syndrome | Obesity | Homeostasis | Insulin resistance | Glucose | Insulin | Metabolic disorders
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 12/2018, Volume 45, Issue 12, pp. 1257 - 1264
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 08/2019, Volume 516, Issue 2, pp. 402 - 407
Journal Article
by Wang, ZK and Chen, RJ and Wang, SL and Li, GW and Zhu, ZZ and Huang, Q and Chen, ZL and Chen, FC and Deng, L and Lan, XP and Hu, T
MOLECULAR MEDICINE REPORTS, ISSN 1791-2997, 01/2018, Volume 17, Issue 1, pp. 683 - 693
A novel diagnostic scheme that includes pancreatic -cell dysfunction analysis for the diagnosis of traumatic multiple organ dysfunction syndrome (MODS) was... 
trauma | MORTALITY | MEDICINE, RESEARCH & EXPERIMENTAL | blood glucose | OXIDATIVE STRESS | SCORE | INSULIN-SECRETION | INJURY | diagnostic scheme | FAILURE | multiple organ dysfunction syndrome | HYPERGLYCEMIA | ONCOLOGY | GLUCOSE | TISSUES | INFLAMMATORY RESPONSE | pancreatic -cell dysfunction | Multiple organ failure | Pancreatic beta cells | Care and treatment | Diagnosis | Health aspects
Journal Article
Nature, ISSN 0028-0836, 03/2012, Volume 483, Issue 7389, pp. 350 - 354
Journal Article
Experimental Cell Research, ISSN 0014-4827, 10/2018, Volume 371, Issue 1, pp. 205 - 213
Recently, SIRT5 was reported to be a predominant desuccinylase and demalonylase in mitochondria. Ablation of SIRT5 enhances the systemic succinylation and... 
Glucolipotoxicity | SIRT5 | β cell | Apoptosis | Insulin secretion | SURVIVAL | beta cell | OXIDATIVE STRESS | LYSINE | MITOCHONDRIA | MEMBRANES | MECHANISMS | CELL BIOLOGY | METABOLISM | ONCOLOGY | INSULIN-RESISTANCE | BAX | REGULATORS
Journal Article