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Cell (Cambridge), ISSN 0092-8674, 06/2012, Volume 149, Issue 6, pp. 1233 - 1244
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Protein Structure, Tertiary | Cell Line | Chromatin - metabolism | Promoter Regions, Genetic | Zinc Fingers | Cell Separation | Erythroblasts - metabolism | Gene Expression Regulation | Male | LIM Domain Proteins - metabolism | DNA-Binding Proteins - chemistry | GATA1 Transcription Factor - metabolism | beta-Globins - genetics | DNA-Binding Proteins - metabolism | Animals | Embryo, Mammalian - cytology | Female | Transcription, Genetic | Mice | LIM Domain Proteins - chemistry | Proteins | Chromatin | Zinc finger proteins | RNA | Developmental biology | Genes | Index Medicus | zinc finger proteins | Ldb1 | transcription | chromatin | looping | hemoglobin
Journal Article
Blood, ISSN 0006-4971, 04/2018, Volume 131, Issue 17, pp. 1960 - 1973
Life Sciences & Biomedicine | Hematology | Science & Technology | Anemia, Sickle Cell - pathology | Cell Line | Fetal Hemoglobin - biosynthesis | Humans | Hematopoietic Stem Cells - pathology | Hematopoietic Stem Cells - metabolism | Genetic Loci | beta-Globins - genetics | Gene Editing | Anemia, Sickle Cell - therapy | beta-Globins - metabolism | Anemia, Sickle Cell - metabolism | CRISPR-Cas Systems | Fetal Hemoglobin - genetics | Anemia, Sickle Cell - genetics | Index Medicus | Abridged Index Medicus
Journal Article
BioEssays, ISSN 0265-9247, 01/2019, Volume 41, Issue 1, pp. e1800164 - n/a
super‐enhancer | transcription regulation | phase separation | mediators | RNA polymerase II | super-enhancer | Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Enhancer Elements, Genetic | Humans | Gene Expression Regulation | Transcription, Genetic | Locus Control Region | RNA Polymerase II - metabolism | beta-Globins - genetics | Transcription elongation | Genes | Gene regulation | RNA polymerase | Ribonucleic acid--RNA | Loci | DNA-directed RNA polymerase | Proteins | Transcription termination | Enhancers | Phase separation | Elongation | Mediator
Journal Article
Nucleic acids research, ISSN 0305-1048, 09/2012, Volume 40, Issue 16, pp. 7718 - 7727
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Cell Line | Chromosomes, Human, Pair 11 - chemistry | Humans | Gene Expression Regulation | Genetic Loci | Locus Control Region | beta-Globins - genetics | CCCTC-Binding Factor | K562 Cells | Chromosomes, Human, Pair 11 - metabolism | Transcription, Genetic | Genome, Human | beta-Globins - biosynthesis | Repressor Proteins - metabolism | Chromatin - chemistry | Index Medicus | Chromatin | Transcription | Protein folding | Gene regulation | Nucleosomes | chromosome 11 | Erythroid cells | Chromosomes | Life Sciences | Modeling and Simulation | Biological Physics | Biochemistry, Molecular Biology | Computer Science | Biophysics | Physics | Gene Regulation, Chromatin and Epigenetics
Journal Article
Biochimica et biophysica acta. Gene regulatory mechanisms, ISSN 1874-9399, 04/2017, Volume 1860, Issue 4, pp. 393 - 404
Journal Article
Molecular therapy, ISSN 1525-0016, 01/2020, Volume 28, Issue 1, pp. 328 - 340
hemoglobinopathies | transplantation | hematopoietic stem cell | locus control region | gene therapy | lentiviral vector | sickle cell disease | ENCODE | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Humans | Hematopoietic Stem Cells - metabolism | Healthy Volunteers | beta-Globins - genetics | Anemia, Sickle Cell - therapy | Phenotype | Animals | Transfection | HEK293 Cells | Locus Control Region - genetics | Lentivirus - genetics | Mice | Genetic Vectors | Transduction, Genetic - methods | Bone Marrow Cells - metabolism | Disease Models, Animal | Genetic Therapy - methods | Phenotypes | Copy number | Genomes | FDA approval | Patients | Vectors (Biology) | Progenitor cells | Hemopoiesis | Efficiency | Hemoglobin | Bone marrow | Gene therapy | Sickle cell disease | Drug dosages | Expression vectors | Index Medicus
Journal Article
The EMBO journal, ISSN 0261-4189, 10/2010, Volume 29, Issue 19, pp. 3260 - 3271
replication | multiprotein complex | transcription | purification | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Oligonucleotides - genetics | DNA-Binding Proteins - physiology | Humans | Nuclear Factor 45 Protein - genetics | DNA Repair - physiology | Nuclear Factor 45 Protein - metabolism | Multiprotein Complexes - genetics | DNA Repair - genetics | DNA-Binding Proteins - genetics | beta-Globins - genetics | Multiprotein Complexes - physiology | DNA-Binding Proteins - metabolism | Nuclear Factor 90 Proteins - metabolism | Multiprotein Complexes - metabolism | p300-CBP Transcription Factors - metabolism | Transcription, Genetic - physiology | beta-Globins - metabolism | DNA Replication - physiology | RNA Interference | p300-CBP Transcription Factors - genetics | Cell Line, Tumor | DNA Replication - genetics | Transcription, Genetic - genetics | Nuclear Factor 90 Proteins - genetics | Index Medicus
Journal Article