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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2013, Volume 110, Issue 32, pp. 13067 - 13072
Journal Article
Journal Article
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 09/2018, Volume 430, Issue 18, pp. 3311 - 3322
Conformational dynamics are increasingly recognized as being essential for enzyme function. However, there is virtually no direct experimental evidence to... 
catalysis | enzymes | H/D-exchange | antimicrobial resistance | β-lactamase | ACTIVE-SITE | ACYLATION | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | RESOLUTION | EXCHANGE-MASS-SPECTROMETRY | CLAVULANIC ACID | ACYL-ENZYME INTERMEDIATE | ALLOSTERIC INHIBITION | beta-lactamase | BINDING
Journal Article
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 12/2018, Volume 19, Issue 12, p. 3808
Journal Article
by Wang, F and Shen, L and Zhou, HY and Wang, SY and Wang, XL and Tao, P
FRONTIERS IN MOLECULAR BIOSCIENCES, ISSN 2296-889X, 07/2019, Volume 6, pp. 47 - 47
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 10/2018, Volume 505, Issue 1, pp. 333 - 337
β-lactamase TEM-1 is potentially useful in the antibody-directed enzyme/prodrug therapy (ADEPT), converting nontoxic prodrugs to toxic agents. The produced... 
Protein engineering | Hydrolase | ADEPT | pH dependency | Nitrocefin | CATALYSIS | MUTANT | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOXORUBICIN | ANTIBODY | PRODRUG ACTIVATION | GENETIC-CODE | EVOLUTION | ENZYME | THERAPY | BIOPHYSICS | GLOBAL SUPPRESSOR | Biocatalysis | Escherichia coli - enzymology | Mutagenesis, Site-Directed |