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Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 02/2018, Volume 62, Issue 2
Journal Article
Bacteriological and antimicrobial susceptibility profile of soft tissue infections from northern India, 01/2004
BACKGROUND: Soft tissue infections require a judicious combination of antimicrobial therapy in addition to surgical debridement to limit tissue loss and... 
Medicine | Soft tissue infection, Antibiogram, Beta lactams, Methicillin resistant Staphylococcus aureus, High level aminoglycoside resistance ms04002
Journal
Journal of Organic Chemistry, ISSN 0022-3263, 06/2018, Volume 83, Issue 11, pp. 6178 - 6185
A simple methodology has been developed for the synthesis of substituted pyrroloisoindolone and pyridoisoindolone via aza-Prins cyclization of endocyclic... 
SYSTEM | GAMMA-LACTAMS | CHEMISTRY, ORGANIC | AZABICYCLIC DERIVATIVES | INHIBITORS | BETA-LACTAMS
Journal Article
The Journal of organic chemistry, ISSN 0022-3263, 02/2019, Volume 84, Issue 4, pp. 1693 - 1705
The previously reported ring-expansion strategy involving hydrolytically prone imidazoline rings was thought to include the formation of a hydrated imidazoline... 
TRANSAMIDATION REACTIONS | CHEMISTRY, ORGANIC | THERMOCHEMISTRY | MACROCYCLES | BETA-LACTAMS
Journal Article
by Gao, X and Shan, CH and Chen, ZH and Liu, Y and Zhao, X and Zhang, A and Yu, P and Galons, H and Lan, Y and Lu, K
ORGANIC & BIOMOLECULAR CHEMISTRY, ISSN 1477-0520, 09/2018, Volume 16, Issue 33, pp. 6096 - 6105
Diversity-oriented synthesis of -lactams was achieved via Ugi/Michael reaction cascades under mild conditions. The intramolecular hydrogen bonding between the... 
DIVERSITY-ORIENTED SYNTHESIS | ACIDS | CHEMISTRY, ORGANIC | BETA-LACTAMS | CYCLIZATION
Journal Article
Nature Reviews Microbiology, ISSN 1740-1526, 07/2018, Volume 16, Issue 7, pp. 394 - 395
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 03/2016, Volume 138, Issue 7, pp. 2178 - 2181
Catalyst-controlled divergent intermolecular cycloadditions of vinylaziridines with alkynes have been developed. By using [Rh(NBD)(2)]BF4 as the catalyst, a [3... 
REARRANGEMENT | ACTIVATION | RING EXPANSION | FACILE SYNTHESIS | ACID | TANDEM | 1,2,3-TRIAZOLES | BOND | CHEMISTRY, MULTIDISCIPLINARY | AZEPINE DERIVATIVES | BETA-LACTAMS | Usage | Chemical properties | Rhodium | Chemical synthesis
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 10/2017, Volume 139, Issue 41, pp. 14707 - 14713
Catalytic asymmetric cycloadditions of reactive ketene intermediates provide new opportunities for the production of chiral heterocyclic molecules. Though... 
SULFUR YLIDES | KETENES | ACIDS | MIXED PHOSPHORUS/SULFUR LIGANDS | CONSTRUCTION | COMPLEXES | QUATERNARY STEREOCENTERS | ASYMMETRIC HYDROGENATION | ALPHA-FLUORINATION | CHEMISTRY, MULTIDISCIPLINARY | BETA-LACTAMS
Journal Article
Organic Letters, ISSN 1523-7060, 01/2018, Volume 20, Issue 2, pp. 449 - 452
Cascade radical cyclization of 1,6-enynes for the synthesis of biologically important gamma-lactams containing alkenyl C-X bonds is reported. In these radical... 
1,7-ENYNES | RING EXPANSION | CHEMISTRY, ORGANIC | MICROBIAL METABOLITE | H INSERTION | CASCADE | LACTACYSTIN | STEREOSELECTIVE-SYNTHESIS | DERIVATIVES | BETA-LACTAMS | ENYNES
Journal Article
Chemical communications (Cambridge, England), ISSN 1359-7345, 08/2016, Volume 52, Issue 67, pp. 10265 - 10268
The diastereoselective synthesis of strained adducts that show cage-like structures has been accomplished directly from allenyl-β-lactams through gold... 
Journal Article
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 2018, Volume 140, Issue 43, pp. 14019 - 14023
Quinolones of the human pathogen Pseudomonas aeruginosa serve as antibacterial weapons and quorum sensing signals and coordinate the production of important... 
TARGET | SYNTHASE | COMPLEX | ENZYME | PQSD | GROWTH | VIRULENCE | CHEMISTRY, MULTIDISCIPLINARY | BETA-LACTAMS | ACTIVITY-BASED PROBES | MOLECULES
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 2014, Volume 69, Issue 5, pp. 1416 - 1423
Emerging evidence supports the use of therapeutic drug monitoring (TDM) of β-lactams for intensive care unit (ICU) patients to optimize drug exposure, although... 
Antimicrobial | Critical care | Dosing | Pharmacokinetics | TDM | Anti-Bacterial Agents - therapeutic use | Intensive Care Units | Internationality | Humans | Surveys and Questionnaires | Drug Monitoring - methods | beta-Lactams - therapeutic use
Journal Article
Bulgarian Journal of Veterinary Medicine, ISSN 1311-1477, 09/2019, Volume 22, Issue 3, pp. 330 - 336
The sensitivity of 80 E. coli strains isolated from canine rectal swabs to antimicrobial drugs was tested in this study. The results showed 47.5% resistance to... 
resistance to beta-lactams | dogs | commensal E.coli
Journal Article
Organic Letters, ISSN 1523-7060, 07/2018, Volume 20, Issue 13, pp. 3833 - 3837
A versatile silver-promoted oxidative cascade reaction of N-aryl-3-alkylideneazetidines with carboxylic acids is reported, providing a very efficient pathway... 
3-ETHYLIDENEAZETIDINES | QUINOLINE | VINYL AZIRIDINES | RING EXPANSION | METHYLENEAZIRIDINES | CHEMISTRY, ORGANIC | 3+2 CYCLOADDITIONS | VINYLAZIRIDINES | DERIVATIVES | BETA-LACTAMS
Journal Article
Organic Letters, ISSN 1523-7060, 02/2017, Volume 19, Issue 4, pp. 874 - 877
The first reductive generation of carbamoyl radicals using photoredox catalysis for their formation is reported. This approach facilitated the development of a... 
1,7-ENYNES | VISIBLE-LIGHT PHOTOCATALYSIS | ACIDS | CONSTRUCTION | OXINDOLES | CHEMISTRY, ORGANIC | CONVENIENT | OLEFINS | YNONES | BETA-LACTAMS
Journal Article
2013, Annals of the New York Academy of Sciences, ISBN 1573318795, Volume 1277, vii, 159
"Bacterial cell walls are unique structures that serve as ideal targets for antimicrobial drugs. Agents that interfere with bacterial cell wall biosynthesis or... 
Anti-infective agents | Bacterial cell walls | Synthesis | Inhibitors | Antibiotics
Book
Journal of Organic Chemistry, ISSN 0022-3263, 08/2015, Volume 80, Issue 16, pp. 8424 - 8429
In this work, an aerobic copper-catalyzed intramolecular C(sp(3))-H amidation has been disclosed, which presents a rare example of copper-catalyzed... 
FUNCTIONALIZATION | OXIDATION | ACTIVATION | DIRECT AMINATION | ARYLATION | C-H OLEFINATION | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | ALKOXYLATION | CARBON-HYDROGEN BONDS | BETA-LACTAMS
Journal Article
Antibiotics, ISSN 2079-6382, 09/2019, Volume 8, Issue 4, p. 165
To evaluate the antimicrobial agent’s stability stored at −80 °C, six β-lactams (meropenem, ertapenem, imipenem, ceftriaxone, ceftazidime, and... 
antimicrobial | frozen drugs | antimicrobial stability | Beta-lactams
Journal Article
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