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1. Full Text Outcomes of vancomycin plus a-lactam versus vancomycin only for treatment of methicillin-resistant staphylococcus aureus bacteremia
by Truong, James and Veillette, John J and Forland, Steve C
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 02/2018, Volume 62, Issue 2
Vancomycin | Beta-lactams | Antimicrobial combinations | Bacteremia | MRSA
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2. Bacteriological and antimicrobial susceptibility profile of soft tissue infections from northern India
by Mohanty, S and Kapil, A and Dhawan, B and Das, B. K
Bacteriological and antimicrobial susceptibility profile of soft tissue infections from northern India, 01/2004
BACKGROUND: Soft tissue infections require a judicious combination of antimicrobial therapy in addition to surgical debridement to limit tissue loss and... 
Medicine | Soft tissue infection, Antibiogram, Beta lactams, Methicillin resistant Staphylococcus aureus, High level aminoglycoside resistance ms04002
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3. Full Text Stereoselective Synthesis of Pyrroloisoindolone and Pyridoisoindolone via aza-Prins Cyclization of Endocyclic N-Acyliminium Ions
by Das, Malay and Saikia, Anil K
Journal of Organic Chemistry, ISSN 0022-3263, 06/2018, Volume 83, Issue 11, pp. 6178 - 6185
A simple methodology has been developed for the synthesis of substituted pyrroloisoindolone and pyridoisoindolone via aza-Prins cyclization of endocyclic... 
SYSTEM | GAMMA-LACTAMS | CHEMISTRY, ORGANIC | AZABICYCLIC DERIVATIVES | INHIBITORS | BETA-LACTAMS
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4. Full Text Rethinking Hydrolytic Imidazoline Ring Expansion: A Common Approach to the Preparation of Medium-Sized Rings via Side-Chain Insertion into [1.4]Oxa- and [1.4]Thiazepinone Scaffolds
by Reutskaya, Elena and Osipyan, Angelina and Sapegin, Alexander and Novikov, Alexander S and Krasavin, Mikhail
The Journal of organic chemistry, ISSN 0022-3263, 02/2019, Volume 84, Issue 4, pp. 1693 - 1705
The previously reported ring-expansion strategy involving hydrolytically prone imidazoline rings was thought to include the formation of a hydrated imidazoline... 
TRANSAMIDATION REACTIONS | CHEMISTRY, ORGANIC | THERMOCHEMISTRY | MACROCYCLES | BETA-LACTAMS
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5. Full Text One-pot synthesis of -lactams by the Ugi and Michael addition cascade reaction
by Gao, X and Shan, CH and Chen, ZH and Liu, Y and Zhao, X and Zhang, A and Yu, P and Galons, H and Lan, Y and Lu, K
ORGANIC & BIOMOLECULAR CHEMISTRY, ISSN 1477-0520, 09/2018, Volume 16, Issue 33, pp. 6096 - 6105
Diversity-oriented synthesis of -lactams was achieved via Ugi/Michael reaction cascades under mild conditions. The intramolecular hydrogen bonding between the... 
DIVERSITY-ORIENTED SYNTHESIS | ACIDS | CHEMISTRY, ORGANIC | BETA-LACTAMS | CYCLIZATION
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6. Full Text Feasting on β-lactams
by Hofer, Ursula
Nature Reviews Microbiology, ISSN 1740-1526, 07/2018, Volume 16, Issue 7, pp. 394 - 395
MICROBIOLOGY | Soil | Microbiota | beta-Lactams | β-Lactam antibiotics
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7. Full Text The Divergent Synthesis of Nitrogen Heterocycles by Rhodium(I)-Catalyzed Intermolecular Cycloadditions of Vinyl Aziridines and Alkynes
by Feng, Jian-Jun and Lin, Tao-Yan and Zhu, Chao-Ze and Wang, Huamin and Wu, Hai-Hong and Zhang, Junliang
Journal of the American Chemical Society, ISSN 0002-7863, 03/2016, Volume 138, Issue 7, pp. 2178 - 2181
Catalyst-controlled divergent intermolecular cycloadditions of vinylaziridines with alkynes have been developed. By using [Rh(NBD)(2)]BF4 as the catalyst, a [3... 
REARRANGEMENT | ACTIVATION | RING EXPANSION | FACILE SYNTHESIS | ACID | TANDEM | 1,2,3-TRIAZOLES | BOND | CHEMISTRY, MULTIDISCIPLINARY | AZEPINE DERIVATIVES | BETA-LACTAMS | Usage | Chemical properties | Rhodium | Chemical synthesis
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8. Beta-lactam resistance mechanisms in pathogens isolated from patients admitted to intensive care unit
by Axente, Carmen and Muntean, Delia and Baditoiu, Luminita and Moldovan, Roxana and Hogea, Elena and Horhat, Florin and Bedreag, Ovidiu and Sandesc, Dorel and Dugaesescu, Dorina and Voicu, Mirela and Dumitrascu, Victor and Licker, Monica
Revista de Chimie, ISSN 0034-7752, 06/2017, Volume 68, Issue 6, pp. 1223 - 1226
Antibiotics | Beta-lactams | Beta-lactamases
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9. Full Text Sequential Visible-Light Photoactivation and Palladium Catalysis Enabling Enantioselective [4+2] Cycloadditions
by Li, Miao-Miao and Wei, Yi and Liu, Jie and Chen, Hong-Wei and Lu, Liang-Qiu and Xiao, Wen-Jing
Journal of the American Chemical Society, ISSN 0002-7863, 10/2017, Volume 139, Issue 41, pp. 14707 - 14713
Catalytic asymmetric cycloadditions of reactive ketene intermediates provide new opportunities for the production of chiral heterocyclic molecules. Though... 
SULFUR YLIDES | KETENES | ACIDS | MIXED PHOSPHORUS/SULFUR LIGANDS | CONSTRUCTION | COMPLEXES | QUATERNARY STEREOCENTERS | ASYMMETRIC HYDROGENATION | ALPHA-FLUORINATION | CHEMISTRY, MULTIDISCIPLINARY | BETA-LACTAMS
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10. Full Text Arylsulfonyl Radical Triggered 1,6-Enyne Cyclization: Synthesis of γ-Lactams Containing Alkenyl C-X Bonds
by Cao, Xia and Cheng, Xiao and Xuan, Jun
Organic Letters, ISSN 1523-7060, 01/2018, Volume 20, Issue 2, pp. 449 - 452
Cascade radical cyclization of 1,6-enynes for the synthesis of biologically important gamma-lactams containing alkenyl C-X bonds is reported. In these radical... 
1,7-ENYNES | RING EXPANSION | CHEMISTRY, ORGANIC | MICROBIAL METABOLITE | H INSERTION | CASCADE | LACTACYSTIN | STEREOSELECTIVE-SYNTHESIS | DERIVATIVES | BETA-LACTAMS | ENYNES
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11. Full Text Stereoselective synthesis of strained cage compounds via gold-catalyzed allene functionalization
by Alcaide, Benito and Almendros, Pedro and Cembellín, Sara and Fernández, Israel and Martínez Del Campo, Teresa
Chemical communications (Cambridge, England), ISSN 1359-7345, 08/2016, Volume 52, Issue 67, pp. 10265 - 10268
The diastereoselective synthesis of strained adducts that show cage-like structures has been accomplished directly from allenyl-β-lactams through gold... 
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12. Full Text Skin test concentrations for systemically administered drugs -- an ENDA/EAACI Drug Allergy Interest Group position paper
by Brockow, K and Garvey, L. H and Aberer, W and Atanaskovic-Markovic, M and Barbaud, A and Bilo, M. B and Bircher, A and Blanca, M and Bonadonna, B and Campi, P and Castro, E and Cernadas, J. R and Chiriac, A. M and Demoly, P and Grosber, M and Gooi, J and Lombardo, C and Mertes, P. M and Mosbech, H and Nasser, S and Pagani, M and Ring, J and Romano, A and Scherer, K and Schnyder, B and Testi, S and Torres, M and Trautmann, A and Terreehorst, I and ENDA EAACI Drug Allergy Interest and ENDA/EAACI Drug Allergy Interest Group and The ENDA/EAACI Drug Allergy Interest Group
Allergy, ISSN 0105-4538, 2013, Volume 68, Issue 6, pp. 702 - 712
Skin tests are of paramount importance for the evaluation of drug hypersensitivity reactions. Drug skin tests are often not carried out because of lack of... 
intradermal test | diagnosis | drug allergy | drug hypersensitivity | skin test | PREDICTIVE-VALUE | IMMUNOLOGY | IMMEDIATE HYPERSENSITIVITY | PATCH TEST | ALLERGY | ORAL PROVOCATION | GENERAL-CONSIDERATIONS | CROSS-REACTIVITY | HYPERSENSITIVITY REACTIONS | BETA-LACTAMS | NONIMMEDIATE REACTIONS | Drug Hypersensitivity - diagnosis | Skin Tests - methods | Hypersensitivity, Delayed - diagnosis | Humans | Sensitivity and Specificity | Hypersensitivity, Immediate - diagnosis | Drugs | Allergy | Online health care information services | Medical tests | Skin | Drug therapy | Allergic reaction | Drug allergy | Diagnostic tests | Allergies
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13. Full Text Competitive Live-Cell Profiling Strategy for Discovering Inhibitors of the Quinolone Biosynthesis of Pseudomonas aeruginosa
by Prothiwa, Michaela and Englmaier, Felix and Böttcher, Thomas
Journal of the American Chemical Society, ISSN 0002-7863, 2018, Volume 140, Issue 43, pp. 14019 - 14023
Quinolones of the human pathogen Pseudomonas aeruginosa serve as antibacterial weapons and quorum sensing signals and coordinate the production of important... 
TARGET | SYNTHASE | COMPLEX | ENZYME | PQSD | GROWTH | VIRULENCE | CHEMISTRY, MULTIDISCIPLINARY | BETA-LACTAMS | ACTIVITY-BASED PROBES | MOLECULES
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14. Full Text An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units
by Wong, Gloria and Brinkman, Alexander and Benefield, Russell J and Carlier, Mieke and De Waele, Jan J and Helali, Najoua El and Frey, Otto and Harbarth, Stephan and Huttner, Angela and McWhinney, Brett and Misset, Benoit and Pea, Federico and Preisenberger, Judit and Roberts, Michael S and Robertson, Thomas A and Roehr, Anka and Sime, Fekade Bruck and Taccone, Fabio Silvio and Ungerer, Jacobus P.J and Lipman, Jeffrey and Roberts, Jason A
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 2014, Volume 69, Issue 5, pp. 1416 - 1423
Emerging evidence supports the use of therapeutic drug monitoring (TDM) of β-lactams for intensive care unit (ICU) patients to optimize drug exposure, although... 
Antimicrobial | Critical care | Dosing | Pharmacokinetics | TDM | Anti-Bacterial Agents - therapeutic use | Intensive Care Units | Internationality | Humans | Surveys and Questionnaires | Drug Monitoring - methods | beta-Lactams - therapeutic use
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15. Full Text Prevalence of resistance to some beta-lactams among commensal canine E. coli isolates
by V. Urumova
Bulgarian Journal of Veterinary Medicine, ISSN 1311-1477, 09/2019, Volume 22, Issue 3, pp. 330 - 336
The sensitivity of 80 E. coli strains isolated from canine rectal swabs to antimicrobial drugs was tested in this study. The results showed 47.5% resistance to... 
resistance to beta-lactams | dogs | commensal E.coli
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16. Full Text Oxidative Cascade Reaction of N-Aryl-3-alkylideneazetidines and Carboxylic Acids: Access to Fused Pyridines
by Cai, Wangshui and Wang, Shuang and Jalani, Hitesh B and Wu, Junxian and Lu, Hongjian and Li, Guigen
Organic Letters, ISSN 1523-7060, 07/2018, Volume 20, Issue 13, pp. 3833 - 3837
A versatile silver-promoted oxidative cascade reaction of N-aryl-3-alkylideneazetidines with carboxylic acids is reported, providing a very efficient pathway... 
3-ETHYLIDENEAZETIDINES | QUINOLINE | VINYL AZIRIDINES | RING EXPANSION | METHYLENEAZIRIDINES | CHEMISTRY, ORGANIC | 3+2 CYCLOADDITIONS | VINYLAZIRIDINES | DERIVATIVES | BETA-LACTAMS
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17. Full Text Photoredox-Catalyzed Reductive Carbamoyl Radical Generation: A Redox-Neutral Intermolecular Addition-Cyclization Approach to Functionalized 3,4-Dihydroquinolin-2-ones
by Petersen, Wade F and Taylor, Richard J. K and Donald, James R
Organic Letters, ISSN 1523-7060, 02/2017, Volume 19, Issue 4, pp. 874 - 877
The first reductive generation of carbamoyl radicals using photoredox catalysis for their formation is reported. This approach facilitated the development of a... 
1,7-ENYNES | VISIBLE-LIGHT PHOTOCATALYSIS | ACIDS | CONSTRUCTION | OXINDOLES | CHEMISTRY, ORGANIC | CONVENIENT | OLEFINS | YNONES | BETA-LACTAMS
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18. Antimicrobial therapeutics reviews
: the bacterial cell wall as an antimicrobial target
by Bush, Karen (Biologist)
2013, Annals of the New York Academy of Sciences, ISBN 1573318795, Volume 1277, vii, 159
"Bacterial cell walls are unique structures that serve as ideal targets for antimicrobial drugs. Agents that interfere with bacterial cell wall biosynthesis or... 
Anti-infective agents | Bacterial cell walls | Synthesis | Inhibitors | Antibiotics
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19. Full Text Copper-Catalyzed Intramolecular Dehydrogenative Amidation of Unactivated C(sp 3 )-H Bonds Using O 2 as the Sole Oxidant
by Wang, Chunxia and Yang, Yudong and Qin, Dekun and He, Zhen and You, Jingsong
Journal of Organic Chemistry, ISSN 0022-3263, 08/2015, Volume 80, Issue 16, pp. 8424 - 8429
In this work, an aerobic copper-catalyzed intramolecular C(sp(3))-H amidation has been disclosed, which presents a rare example of copper-catalyzed... 
FUNCTIONALIZATION | OXIDATION | ACTIVATION | DIRECT AMINATION | ARYLATION | C-H OLEFINATION | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | ALKOXYLATION | CARBON-HYDROGEN BONDS | BETA-LACTAMS
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20. Full Text Stability of Biological Activity of Frozen β-lactams over Time as Assessed by Time-Lapsed Broth Microdilutions
by Leite, Gleice and Lawandi, Alexander and Cheng, Matthew P and Lee, Todd
Antibiotics, ISSN 2079-6382, 09/2019, Volume 8, Issue 4, p. 165
To evaluate the antimicrobial agent’s stability stored at −80 °C, six β-lactams (meropenem, ertapenem, imipenem, ceftriaxone, ceftazidime, and... 
antimicrobial | frozen drugs | antimicrobial stability | Beta-lactams
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