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CHEMICAL COMMUNICATIONS, ISSN 1359-7345, 07/2018, Volume 54, Issue 57, pp. 7995 - 7998
Understanding of amyloid aggregation in terms of thermodynamics and kinetics is still limited. We herein examined the mechanism of 2-microglobulin... 
ISOTHERMAL TITRATION CALORIMETRY | BETA-MICROGLOBULIN | HEAT | PROTEINS | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 04/2011, Volume 71, Issue 7, pp. 2600 - 2610
Bone metastasis is one of the predominant causes of cancer lethality. This study demonstrates for the first time how beta 2-microglobulin (beta 2-M) supports... 
HUMAN PROSTATE-CANCER | BETA-MICROGLOBULIN | TRANSFERRIN RECEPTOR | ONCOLOGY | GROWTH | CLASS-I | SERUM BETA-2-MICROGLOBULIN | FACTOR EXPRESSION | ELEMENT-BINDING PROTEIN | IRON OVERLOAD | CARCINOMA
Journal Article
TRANSPLANTATION, ISSN 0041-1337, 04/2017, Volume 101, Issue 4, pp. E153 - E154
Journal Article
PLOS ONE, ISSN 1932-6203, 12/2015, Volume 10, Issue 12
D76N is the first natural variant of human beta-2 microglobulin (beta 2m) so far identified. Contrary to the wt protein, this mutant readily forms amyloid... 
BETA-MICROGLOBULIN | GENE | ROLES | FORM | STABILITY | MULTIDISCIPLINARY SCIENCES | DYNAMICS | SYSTEMIC AMYLOIDOSIS | MODEL | PROTEINS | AGGREGATION
Journal Article
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 2012, Volume 23, Issue 6, pp. 1087 - 1096
Journal Article
Clinical Science, ISSN 0143-5221, 08/2018, Volume 132, Issue 16, pp. 1855 - 1874
By employing a proteomic analysis on supernatant of mechanically stretched cardiomyocytes, we found that stretch induced a significantly high level of beta-2... 
MEDICINE, RESEARCH & EXPERIMENTAL | BETA-MICROGLOBULIN | CELLS | PRESSURE-OVERLOAD | INDUCED HYPERTROPHY | IN-VITRO | PROTEIN | MYOCYTES | RAT | STRETCH | HEART-FAILURE
Journal Article
by Chai, DD and Li, KS and Du, HF and Yang, SS and Yang, R and Xu, Y and Lian, XW
BMC CANCER, ISSN 1471-2407, 03/2019, Volume 19
BackgroundPrevious studies have demonstrated that 2-microglobulin (2M) promotes the growth and survival of a variety of cancer cells and has different... 
beta 2M | ACTIVATION | PROTEIN | METASTASIS | VEGF | INVOLVEMENT | Regulatory | TUMOR | Breast cancer | SERUM | Molecular | Mechanism | BETA-MICROGLOBULIN | ONCOLOGY | GROWTH | EXPRESSION
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 01/2011, Volume 108, Issue 4, pp. 1314 - 1319
Atomic-level structural investigation of the key conformational intermediates of amyloidogenesis remains a challenge. Here we demonstrate the utility of... 
MECHANISM | PROTEIN AGGREGATION | dialysis-related amyloidosis | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | crystallization chaperones | prefibrillar intermediates | ANTIBODY FRAGMENTS | BETA-MICROGLOBULIN | SCRAPIE | DISEASES | FIBRILS | amyloid fibrils | NEUTRAL PH | INSIGHTS
Journal Article
Journal Article
JOURNAL OF PHYSICAL CHEMISTRY B, ISSN 1520-6106, 03/2017, Volume 121, Issue 12, pp. 2603 - 2613
Oligomer species of amyloid beta (A beta) peptides are intensively investigated because of their relevance to Alzheimer's disease (AD), and a stable oligomer... 
INSULIN | BETA OLIGOMERS | CELLS | BETA-MICROGLOBULIN | ALZHEIMERS-DISEASE | NEURONS | CHEMISTRY, PHYSICAL | QUARTZ-CRYSTAL MICROBALANCE | TOXICITY | AMYLOID FIBRIL FORMATION | AGGREGATION
Journal Article
MOLECULAR BIOSYSTEMS, ISSN 1742-206X, 2016, Volume 12, Issue 3, pp. 850 - 859
Beta-2 microglobulin (beta 2m) is an amyloidogenic protein belongs to the immunoglobulin superfamily, responsible for the dialysis-related amyloidosis (DRA).... 
BETA-MICROGLOBULIN | COMPLEX | FORM | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | FLEXIBILITY | DISEASE | MECHANISMS | MUTATIONS | D-STRAND
Journal Article
Journal Article
CANCER, ISSN 0008-543X, 02/2016, Volume 122, Issue 4, pp. 565 - 573
BACKGROUND A high pretreatment (2)-microglobulin (B2M) level is associated with inferior survival outcomes in patients with chronic lymphocytic leukemia.... 
chemoimmunotherapy | CELLS | PREDICTOR | CYCLOPHOSPHAMIDE | FLUDARABINE | ibrutinib | GLOMERULAR-FILTRATION-RATE | IN-VITRO | chronic lymphocytic leukemia | THERAPY | ONCOLOGY | beta-microglobulin | BETA-2-MICROGLOBULIN | RITUXIMAB | BTK inhibitor | MINIMAL RESIDUAL DISEASE
Journal Article
Joint Bone Spine, ISSN 1297-319X, 03/2019, Volume 86, Issue 2, pp. 233 - 238
Beta-2-microglobulin (β2M) dialysis-related amyloidosis (DRA), a disabiliting joint disease, has been initially reported in patients under long-term dialysis.... 
Arthropathy | 2-microglobulin | Dialysis | Amyloidosis | Magnetic resonance imaging | PATHOGENESIS | BETA-MICROGLOBULIN AMYLOIDOSIS | HEMODIALYSIS | PREVALENCE | RHEUMATOLOGY | Arthritis | Index Medicus
Journal Article