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2007, ISBN 1852339616, xi, 298
Book
Neuron (Cambridge, Mass.), ISSN 0896-6273, 06/2010, Volume 66, Issue 5, pp. 631 - 645
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Humans | Mice, Transgenic | Alzheimer Disease - pathology | tau Proteins - biosynthesis | Amyloid beta-Protein Precursor - genetics | Animals | tau Proteins - genetics | tau Proteins - physiology | Alzheimer Disease - metabolism | Mice | Alzheimer Disease - genetics | Amyloid beta-Protein Precursor - physiology | Amyloid beta-Protein Precursor - biosynthesis | Disease Models, Animal | Oligomers | Medical colleges | Analysis | Amyloid beta-protein | Genetic engineering | Alzheimer's disease | Investigations | Aging | Pathology | Brain | Mutation | Alzheimers disease | Rodents | Index Medicus
Journal Article
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The Amyloid Precursor Protein Has a Flexible Transmembrane Domain and Binds Cholesterol
Science (American Association for the Advancement of Science), ISSN 0036-8075, 6/2012, Volume 336, Issue 6085, pp. 1168 - 1171
Micelles | REPORTS | Lipids | Protein precursors | Titration | Biochemistry | Nuclear magnetic resonance | Amyloids | Cholesterols | Curvature | Binding sites | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Organic mental disorders. Neuropsychology | Intermolecular phenomena | Psychology. Psychoanalysis. Psychiatry | Interactions. Associations | Adult and adolescent clinical studies | Molecular biophysics | Psychopathology. Psychiatry | Biological and medical sciences | Medical sciences | Protein Structure, Tertiary | Amino Acid Sequence | Peptide Fragments - metabolism | Electron Spin Resonance Spectroscopy | Protein Structure, Secondary | Amyloid beta-Protein Precursor - chemistry | Humans | Molecular Sequence Data | Cholesterol - metabolism | Amino Acid Motifs | Peptide Fragments - chemistry | Amyloid beta-Protein Precursor - genetics | Amyloid beta-Protein Precursor - metabolism | Nuclear Magnetic Resonance, Biomolecular | Protein Binding | Mutation | Binding Sites | Peptide Fragments - genetics | Amyloid beta-protein | Physiological aspects | Development and progression | Health aspects | Alzheimer's disease | Cholesterol | Membrane proteins | Proteins | Membranes | Index Medicus | Precursors | Cleavage | Electron paramagnetic resonance
Journal Article
Nature reviews. Drug discovery, ISSN 1474-1776, 03/2010, Volume 9, Issue 3, pp. 237 - 248
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Immunotherapy - methods | Humans | Alzheimer Disease - pathology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Brain - metabolism | Amyloid - metabolism | Amyloidosis - immunology | Amyloid - biosynthesis | Amyloidosis - etiology | Alzheimer Disease - immunology | Drug Evaluation, Preclinical - methods | Prion Diseases - drug therapy | Prion Diseases - immunology | Alzheimer Disease - drug therapy | Central Nervous System Diseases - immunology | Amyloidosis - drug therapy | Prion Diseases - pathology | Peptides - pharmacology | Brain - drug effects | Central Nervous System Diseases - etiology | Animals | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Central Nervous System Diseases - drug therapy | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Peptides - therapeutic use | Amyloidosis | Research | Drug therapy | Alzheimer's disease | Health aspects | Risk factors | Index Medicus
Journal Article
Annual review of neuroscience, ISSN 0147-006X, 07/2011, Volume 34, Issue 1, pp. 185 - 204
BACE1 | Aging | α-secretase | γ-secretase | Neurodegeneration | Dementia | Brain - metabolism | Amyloidogenic Proteins - metabolism | Animals | Models, Biological | Amyloid beta-Protein Precursor - chemistry | Humans | Alzheimer Disease - metabolism | Amyloid beta-Protein Precursor - metabolism | Alzheimer Disease - genetics | Alzheimer Disease - pathology | Brain | Amyloid beta-protein | Physiological aspects | Development and progression | Genetic aspects | Health aspects | Alzheimer's disease | Proteins | Alzheimers disease | Older people | Index Medicus | dementia | aging
Journal Article
Cellular and molecular life sciences : CMLS, ISSN 1420-682X, 1/2016, Volume 73, Issue 1, pp. 217 - 236
Life Sciences | Biochemistry, general | Neuroprotection | Life Sciences, general | Synaptotoxicity | Knockout mouse | MMP-24 | Neurodegenerative disease | Biomedicine general | Cell Biology | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Humans | Matrix Metalloproteinases, Membrane-Associated - analysis | Male | Amyloid beta-Protein Precursor - analysis | Cognition | Alzheimer Disease - pathology | Spatial Learning | Gene Deletion | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | HEK293 Cells | Female | Hippocampus - enzymology | Alzheimer Disease - physiopathology | Mice, Inbred C57BL | Mice, Transgenic | Amyloid Precursor Protein Secretases - analysis | Hippocampus - pathology | Alzheimer Disease - enzymology | Matrix Metalloproteinases, Membrane-Associated - genetics | Hippocampus - metabolism | Amyloid Precursor Protein Secretases - metabolism | Animals | Long-Term Potentiation | Amyloid beta-Peptides - analysis | Alzheimer Disease - genetics | Matrix Metalloproteinases, Membrane-Associated - metabolism | Hippocampus - physiopathology | Analysis | Amyloid beta-protein | Genetically modified organisms | Resveratrol | Genetic engineering | Amyloidosis | Alzheimer's disease | Proteins | Nervous system | Membranes | Peptides | Alzheimers disease | Index Medicus | Neurons and Cognition | Alzheimer Disease | Matrix Metalloproteinases, Membrane-Associated | Amyloid Precursor Protein Secretases | Amyloid beta-Peptides | Amyloid beta-Protein Precursor | Hippocampus
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