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Immunity, ISSN 1074-7613, 09/2015, Volume 43, Issue 3, pp. 451 - 462
Endoplasmic reticulum (ER) stress is observed in many human diseases, often associated with inflammation. ER stress can trigger inflammation through... 
LISTERIA-MONOCYTOGENES | CYTOCHROME-C | MESSENGER-RNA | BRUCELLA-ABORTUS | INDUCED APOPTOSIS | ER STRESS | THIOREDOXIN-INTERACTING PROTEIN | SECRETION | IMMUNOLOGY | TRANSCRIPTION FACTOR | CELL-DEATH | Caspase 2 - genetics | Inflammasomes - metabolism | Reactive Oxygen Species - metabolism | Brucella abortus - physiology | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | BH3 Interacting Domain Death Agonist Protein - genetics | Caspase 2 - metabolism | Mitochondria - immunology | Endoplasmic Reticulum Stress - genetics | Endoplasmic Reticulum Stress - immunology | Caspase 2 - immunology | Host-Pathogen Interactions - immunology | DNA-Binding Proteins - metabolism | Mitochondria - genetics | Brucella abortus - immunology | Interleukin-1beta - metabolism | Reactive Oxygen Species - immunology | HEK293 Cells | Transcription Factors - immunology | BH3 Interacting Domain Death Agonist Protein - metabolism | Carrier Proteins - immunology | Macrophages - immunology | Macrophages - microbiology | Protein-Serine-Threonine Kinases - metabolism | RNA Interference - immunology | DNA-Binding Proteins - immunology | Endoribonucleases - metabolism | Mice, Inbred C57BL | Cells, Cultured | Interleukin-1beta - immunology | Mitochondria - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Regulatory Factor X Transcription Factors | Blotting, Western | Mice, Knockout | Transcription Factors - metabolism | Carrier Proteins - genetics | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | Inflammasomes - immunology | BH3 Interacting Domain Death Agonist Protein - immunology | Protein-Serine-Threonine Kinases - immunology | Endoribonucleases - immunology | Medical colleges | Stress (Physiology) | Mitochondrial DNA | Analysis | Cytochrome | Bacterial infections | Dehydrogenases | Infections | Inflammation | Proteins | Studies | Mitochondria | Rodents | Ligands | Endoplasmic reticulum | Deoxyribonucleic acid--DNA | Apoptosis
Journal Article
Immunologic Research, ISSN 0257-277X, 10/2011, Volume 51, Issue 1, pp. 45 - 60
Complement system activation plays an important role in both innate and acquired immunity. Activation of the complement and the subsequent formation of C5b-9... 
Allergology | Signal transduction | Immunology | Medicine & Public Health | Cell cycle | Internal Medicine | Membrane attack complex | C5b-9 terminal complement complex | Transcriptional regulation | Medicine/Public Health, general | Apoptosis | ACTIVATED PROTEIN-KINASE | SYSTEMIC LUPUS-ERYTHEMATOSUS | GUILLAIN-BARRE-SYNDROME | ULCERATIVE-COLITIS | GLOMERULAR EPITHELIAL-CELLS | C5B-9 COMPLEX | IMMUNOLOGY | S-PROTEIN | MANNAN-BINDING LECTIN | ACUTE MYOCARDIAL-INFARCTION | SMOOTH-MUSCLE-CELLS | Forkhead Transcription Factors - immunology | CDC2 Protein Kinase | Complement Membrane Attack Complex - metabolism | Cyclin-Dependent Kinase 4 - genetics | Humans | Caspase 8 - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Complement Membrane Attack Complex - immunology | MAP Kinase Signaling System - immunology | Phosphatidylinositol 3-Kinases - immunology | Cell Cycle Proteins - immunology | Cyclin B - immunology | Forkhead Transcription Factors - metabolism | Muscle Proteins - metabolism | bcl-Associated Death Protein - metabolism | Cell Membrane - metabolism | Phosphorylation - immunology | Cyclin-Dependent Kinases | Proto-Oncogene Proteins c-akt - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | Cyclin-Dependent Kinase 2 - metabolism | Mitogen-Activated Protein Kinase 3 - immunology | Muscle Proteins - immunology | G1 Phase - immunology | S Phase - immunology | Nerve Tissue Proteins - immunology | Cell Cycle Proteins - metabolism | bcl-Associated Death Protein - immunology | Cyclin-Dependent Kinase 4 - metabolism | Nerve Tissue Proteins - metabolism | Caspase 8 - immunology | Animals | Apoptosis - immunology | Proto-Oncogene Proteins c-akt - immunology | Mitogen-Activated Protein Kinase 3 - metabolism | BH3 Interacting Domain Death Agonist Protein - immunology | Cyclin B - metabolism | Cell Membrane - immunology | Forkhead Box Protein O1 | Cyclin-Dependent Kinase 2 - immunology | Medical colleges | Membranes | Immune system | apoptosis | membrane attack complex | cell cycle | signal transduction | transcriptional regulation
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 05/2009, Volume 69, Issue 9, pp. 3986 - 3994
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 09/2006, Volume 80, Issue 3, pp. 509 - 520
Journal Article
Journal Article
International Immunology, ISSN 0953-8178, 4/2008, Volume 20, Issue 4, pp. 543 - 553
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2008, Volume 105, Issue 52, pp. 20840 - 20845
On their entry into the thymus, developing lymphocyte progenitors depend on signaling from the pre-T cell receptor (pre-TCR), which orchestrates... 
T lymphocytes | Thymocytes | Cell death | B lymphocytes | Cell lines | Cell cycle | Gene expression regulation | Progenitor cells | Apoptosis | T cell antigen receptors | T cell development | Pre-TCR signaling | BCL2 family | APOPTOSIS | HOMEOSTASIS | ACTIVATION | cell death | MULTIDISCIPLINARY SCIENCES | DEATH | MECHANISMS | pre-TCR signaling | T-CELL-RECEPTOR | BAX | CHECKPOINT | BCL-2 FAMILY-MEMBERS | NF-KAPPA-B | Cell Nucleus - immunology | Forkhead Transcription Factors - immunology | Cell Proliferation | Gene Rearrangement, T-Lymphocyte - genetics | Quantitative Trait Loci - immunology | Cell Death - immunology | Cell Survival - genetics | BH3 Interacting Domain Death Agonist Protein - genetics | Proto-Oncogene Proteins c-akt - genetics | Tumor Suppressor Protein p53 - genetics | Cell Differentiation - genetics | Lymphoid Progenitor Cells - immunology | Bcl-2-Like Protein 11 | Cell Death - genetics | Proto-Oncogene Proteins - immunology | Apoptosis Regulatory Proteins - genetics | DNA Damage - genetics | Receptors, Antigen, T-Cell - immunology | Active Transport, Cell Nucleus - genetics | Apoptosis Regulatory Proteins - immunology | Membrane Proteins - genetics | Membrane Proteins - immunology | Proto-Oncogene Proteins - genetics | DNA Damage - immunology | Tumor Suppressor Protein p53 - immunology | Cell Survival - immunology | Forkhead Transcription Factors - genetics | Mice, Knockout | Cell Differentiation - immunology | Animals | Proto-Oncogene Proteins c-akt - immunology | Cell Nucleus - genetics | Gene Rearrangement, T-Lymphocyte - immunology | BH3 Interacting Domain Death Agonist Protein - immunology | Active Transport, Cell Nucleus - immunology | Mice | Receptors, Antigen, T-Cell - genetics | Forkhead Box Protein O3 | Quantitative Trait Loci - genetics | Antigen receptors, T cell | Receptors | Cellular control mechanisms | Lymphocyte transformation | Research | Properties | T cells | Biological Sciences
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 2012, Volume 39, Issue 4, pp. 332 - 346
Abstract Negative regulation of B cell activation by cognate immune complexes plays an important homeostatic role in suppressing B cell hyperactivity and... 
Allergy and Immunology | Fas | B-lymphocytes | Caspases | FcγRIIB | Apoptosis | Fc gamma RIIB | ACTIVATED PROTEIN-KINASE | DNA-DAMAGE | MITOCHONDRIA | DEATH | IMMUNOLOGY | P53 | LYSOSOMAL MEMBRANE PERMEABILIZATION | TRIGGERS APOPTOSIS | CASPASE | ANTIGEN RECEPTOR | LYMPHOCYTES | Humans | Male | BH3 Interacting Domain Death Agonist Protein - genetics | Mitochondria - immunology | Fas Ligand Protein - immunology | Tumor Suppressor Protein p53 - genetics | Caspase 8 - genetics | Signal Transduction - immunology | fas Receptor - immunology | Mice, Inbred MRL lpr | Receptors, IgG - genetics | fas Receptor - genetics | Antigen-Antibody Complex - genetics | Lysosomes - pathology | B-Lymphocytes - pathology | B-Lymphocytes - metabolism | Disease Models, Animal | Lupus Nephritis - pathology | bcl-Associated Death Protein - genetics | Lupus Nephritis - genetics | Gene Expression Regulation - immunology | bcl-Associated Death Protein - immunology | Lupus Nephritis - immunology | Signal Transduction - genetics | Tumor Suppressor Protein p53 - immunology | Mitochondria - pathology | Receptors, IgG - immunology | Receptors, Antigen, B-Cell - immunology | Mice, Knockout | Caspase 8 - immunology | Animals | B-Lymphocytes - immunology | BH3 Interacting Domain Death Agonist Protein - immunology | Receptors, Antigen, B-Cell - genetics | Mice | Antigen-Antibody Complex - immunology | Fas Ligand Protein - genetics | Lysosomes - immunology | Glomerulonephritis | Animal models | Fas antigen | Bcl-2 protein | CD95 antigen | Proteinase | Caspase | Nuclear transport | p53 protein | BID protein | death receptors | Signal transduction | Cell activation | Mitochondria | FasL protein | Systemic lupus erythematosus | Lymphocytes B | Autoimmune diseases | Antigen-antibody complexes
Journal Article
Journal Article
Journal of Immunotherapy, ISSN 1524-9557, 01/2012, Volume 35, Issue 1, pp. 23 - 31
Clinical applications of human interferon (IFN)-alpha have met with varying degrees of success. Nevertheless, key molecules in cell viability regulated by... 
IFN-α | apoptosis | cell viability | TRAIL | BID | MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNOAFFINITY CAPILLARY-ELECTROPHORESIS | INDUCED APOPTOSIS | DEATH | IMMUNOLOGY | CLEAVAGE | IFN-alpha | CYTOCHROME-C | MITOCHONDRIAL-MEMBRANE PERMEABILIZATION | INTERFERON | ONCOLOGY | PATHWAY | BAX | BCL-2 PROTEINS | Interferon-alpha - pharmacology | RNA, Small Interfering - genetics | Adenocarcinoma - pathology | Humans | Ovarian Neoplasms - pathology | Cell Survival - genetics | BH3 Interacting Domain Death Agonist Protein - genetics | Membrane Potential, Mitochondrial - drug effects | Membrane Potential, Mitochondrial - genetics | Female | Receptor, Interferon alpha-beta - genetics | Gene Expression Regulation, Neoplastic - drug effects | Ovarian Neoplasms - drug therapy | BH3 Interacting Domain Death Agonist Protein - metabolism | Gene Expression Regulation, Neoplastic - genetics | Receptor, Interferon alpha-beta - metabolism | Cell Survival - drug effects | Adenocarcinoma - immunology | Transgenes - genetics | TNF-Related Apoptosis-Inducing Ligand - immunology | Interferon-Stimulated Gene Factor 3, gamma Subunit - genetics | TNF-Related Apoptosis-Inducing Ligand - metabolism | Adenocarcinoma - drug therapy | Interferon-Stimulated Gene Factor 3, gamma Subunit - metabolism | Receptor, Interferon alpha-beta - immunology | Interferon-Stimulated Gene Factor 3, gamma Subunit - immunology | Cell Line, Tumor | BH3 Interacting Domain Death Agonist Protein - immunology | TNF-Related Apoptosis-Inducing Ligand - genetics | Apoptosis | Ovarian Neoplasms - immunology
Journal Article