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Journal Article
Journal Article
Journal Article
Cancer Discovery, ISSN 2159-8274, 09/2011, Volume 1, Issue 4, pp. 352 - 365
Cancers with specific genetic mutations are susceptible to selective kinase inhibitors. However, there is a wide spectrum of benefit among cancers harboring... 
CELL LUNG-CANCER | BREAST-CANCER | GEFITINIB | ACTIVATION | GROWTH-FACTOR-RECEPTOR | MET AMPLIFICATION | ONCOLOGY | INDUCED APOPTOSIS | PHASE-II | MUTATIONS | EGFR | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Receptor, ErbB-2 - genetics | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Receptor, ErbB-2 - metabolism | Apoptosis - genetics | BH3 Interacting Domain Death Agonist Protein - genetics | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Proto-Oncogene Proteins - biosynthesis | Receptor, Epidermal Growth Factor - metabolism | Bcl-2-Like Protein 11 | Apoptosis Regulatory Proteins - genetics | Female | Membrane Proteins - metabolism | Receptor, ErbB-2 - antagonists & inhibitors | Retrospective Studies | BH3 Interacting Domain Death Agonist Protein - metabolism | Oncogenes | Apoptosis Regulatory Proteins - biosynthesis | Lung Neoplasms - genetics | Proto-Oncogene Proteins - metabolism | Membrane Proteins - genetics | Proto-Oncogene Proteins - genetics | Apoptosis Regulatory Proteins - metabolism | Phosphatidylinositol 3-Kinases - genetics | Membrane Proteins - biosynthesis | Animals | Signal Transduction - drug effects | Mice, Nude | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Mice | Protein Kinase Inhibitors - pharmacology | Cohort Studies | oncogene addiction | apoptosis | HER2 | BIM
Journal Article
Biochemical Journal, ISSN 0264-6021, 05/2015, Volume 467, Issue 3, pp. 495 - 505
After exposure to stressful stimuli, apoptotic signals can be relayed to mitochondria by pro-apoptotic activator proteins, tBid (truncated Bid/p15) and Bim... 
Bax | Fluorescence | Cardiolipin | B-cell lymphoma 2 (Bcl-2) proteins | Cholesterol | Apoptosis | RAT-LIVER | PROTEIN | PROAPOPTOTIC BAX | BIOCHEMISTRY & MOLECULAR BIOLOGY | apoptosis | MITOCHONDRIAL-MEMBRANE | cardiolipin | CONFORMATIONAL-CHANGE | fluorescence | cholesterol | CYTOCHROME-C RELEASE | BCL-2 FAMILY | CARDIOLIPIN PROVIDES | BINDING | Mitochondria, Liver - metabolism | Humans | bcl-2 Homologous Antagonist-Killer Protein - deficiency | bcl-2 Homologous Antagonist-Killer Protein - genetics | BH3 Interacting Domain Death Agonist Protein - genetics | Bcl-2-Like Protein 11 | BH3 Interacting Domain Death Agonist Protein - chemistry | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | bcl-2-Associated X Protein - genetics | Proto-Oncogene Proteins - metabolism | Recombinant Proteins - metabolism | Mutagenesis, Site-Directed | Membrane Proteins - genetics | bcl-2-Associated X Protein - metabolism | Recombinant Proteins - chemistry | Proto-Oncogene Proteins - genetics | Cardiolipins - metabolism | Recombinant Proteins - genetics | Permeability | Cholesterol - metabolism | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Mitochondrial Membranes - metabolism | Animals | Models, Biological | Membrane Lipids - metabolism | Liposomes - metabolism | Protein Conformation | Mice | Apoptosis - physiology
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 2018, Volume 25, Issue 2, pp. 282 - 293
Journal Article