X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (493) 493
humans (332) 332
animals (277) 277
biased agonism (271) 271
ligands (198) 198
pharmacology & pharmacy (191) 191
biochemistry & molecular biology (169) 169
biased signaling (156) 156
functional selectivity (148) 148
signal transduction (148) 148
activation (135) 135
protein-coupled receptors (108) 108
beta-arrestin (106) 106
receptors, g-protein-coupled - metabolism (105) 105
article (104) 104
drug discovery (102) 102
hek293 cells (95) 95
gpcr (93) 93
arrestin (89) 89
pharmacology (86) 86
g protein-coupled receptor (83) 83
g proteins (83) 83
cell biology (81) 81
mice (79) 79
neurosciences (79) 79
signal transduction - drug effects (79) 79
beta-arrestins (77) 77
proteins (77) 77
crystal-structure (68) 68
g protein-coupled receptors (67) 67
protein-coupled receptor (67) 67
male (66) 66
biased ligand (65) 65
arrestins - metabolism (63) 63
beta-adrenergic receptor (63) 63
chemistry, medicinal (61) 61
phosphorylation (60) 60
analysis (58) 58
7-transmembrane receptors (54) 54
protein binding (53) 53
physiological aspects (52) 52
β-arrestin (52) 52
receptors (51) 51
in-vivo (50) 50
membrane proteins (50) 50
mu-opioid receptor (49) 49
biased agonist (47) 47
biased ligands (47) 47
cho cells (47) 47
models, molecular (47) 47
protein conformation (47) 47
receptor (47) 47
agonist (46) 46
cricetulus (45) 45
ligand (45) 45
desensitization (44) 44
drug design (44) 44
female (42) 42
research (42) 42
binding (41) 41
receptors, g-protein-coupled - agonists (41) 41
efficacy (40) 40
internalization (40) 40
signal transduction - physiology (39) 39
allosteric modulation (37) 37
rats (37) 37
signaling (35) 35
binding sites (34) 34
multidisciplinary sciences (34) 34
structure-activity relationship (34) 34
biased signalling (33) 33
cyclic amp - metabolism (33) 33
peptides (33) 33
cells (32) 32
dose-response relationship, drug (32) 32
gtp-binding proteins - metabolism (32) 32
protein (32) 32
receptors, g-protein-coupled - chemistry (32) 32
discovery (31) 31
biology (30) 30
endocrinology & metabolism (30) 30
amino acid sequence (29) 29
g protein (29) 29
models, biological (29) 29
morphine (29) 29
cricetinae (28) 28
endocytosis (28) 28
gene expression (27) 27
research article (27) 27
review (27) 27
health aspects (26) 26
identification (26) 26
life sciences (26) 26
biophysics (25) 25
expression (25) 25
kinases (25) 25
molecular dynamics (25) 25
antagonist (24) 24
conformational-changes (24) 24
g-protein (24) 24
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2016, Volume 113, Issue 50, pp. E8178 - E8186
Journal Article
British Journal of Anaesthesia, ISSN 0007-0912, 11/2018, Volume 121, Issue 5, pp. 1105 - 1114
Opioids are characterised as classical (mu, delta, and kappa) along with the non-classical nociceptin/orphanin FQ (N/OFQ) receptor or NOP. Targeting NOP has... 
opioid receptors | pain | respiratory depression | cebranopadol | analgesia | biased agonist | NOP receptor ligands | tolerance | opioids | ORPHANIN-FQ | BIASED LIGAND | PHARMACOLOGICAL CHARACTERIZATION | BENZHYDRYL-NORTROPANE ANALOGS | MU-OPIOID RECEPTOR | MICE LACKING | MOUSE MODELS | MORPHINE-TOLERANCE | PARTIAL AGONIST | ANESTHESIOLOGY | NEUROGENIC DETRUSOR OVERACTIVITY | Pain
Journal Article
Annual Review of Pharmacology and Toxicology, ISSN 0362-1642, 2012, Volume 52, pp. 153 - 178
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2012, Volume 109, Issue 21, pp. 8304 - 8309
Journal Article
FEBS Letters, ISSN 0014-5793, 11/2017, Volume 591, Issue 22, pp. 3771 - 3780
The 2‐series of prostaglandin E (PGE2) is regarded as a pro‐cancer prostanoid, whereas the 1‐series (PGE1) and the 3‐series (PGE3) are considered to act as... 
PGE 2 | PGE 3 | biased ligands | E‐type prostanoid 4 receptors | PGE 1 | TCF/β‐catenin signaling | TCF/β-catenin signaling | E-type prostanoid 4 receptors | PGE | Index Medicus
Journal Article