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British Journal of Pharmacology, ISSN 0007-1188, 02/2008, Volume 153, Issue 4, pp. 805 - 819
Background and purpose: Certain nuclear receptors (NRs) such as the constitutive androstane receptor (CAR), pregnane X receptor (PXR) and farnesoid X receptor... 
FXR | MDR1 | P‐glycoprotein | PXR | cytochrome P450 | CAR | P-glycoprotein | Cytochrome P450 | REPORTER GENE ASSAY | P-GLYCOPROTEIN EXPRESSION | BILE-ACID RECEPTOR | PRIMARY CULTURES | PREGNANE-X-RECEPTOR | IN-VITRO | MESSENGER-RNA | CONSTITUTIVE ANDROSTANE RECEPTOR | CRYOPRESERVED HUMAN HEPATOCYTES | PHARMACOLOGY & PHARMACY | cytochrome p450 | MDR1 EXPRESSION | Phenobarbital - pharmacology | Up-Regulation | Aryl Hydrocarbon Hydroxylases - biosynthesis | Intestinal Mucosa - metabolism | Epithelial Cells - metabolism | Epithelial Cells - drug effects | Humans | Hepatocytes - metabolism | Receptors, Cytoplasmic and Nuclear - biosynthesis | Multidrug Resistance-Associated Proteins - biosynthesis | Receptors, Steroid - agonists | Intestinal Mucosa - drug effects | Dose-Response Relationship, Drug | RNA, Messenger - biosynthesis | Dexamethasone - pharmacology | ATP-Binding Cassette Transporters - genetics | DNA-Binding Proteins - agonists | Chenodeoxycholic Acid - pharmacology | Cell Culture Techniques | Hepatocytes - drug effects | Caco-2 Cells | Cytochrome P-450 CYP3A - biosynthesis | ATP Binding Cassette Transporter, Subfamily B, Member 1 - biosynthesis | Pregnenolone Carbonitrile - pharmacology | Cells, Cultured | Enzyme Induction | Receptors, Cytoplasmic and Nuclear - agonists | ATP Binding Cassette Transporter, Subfamily B | ATP-Binding Cassette Transporters - biosynthesis | Membrane Transport Proteins - biosynthesis | Cytochrome P-450 Enzyme System - biosynthesis | Cytochrome P-450 Enzyme System - genetics | Oxidoreductases, N-Demethylating - biosynthesis | Rifampin - pharmacology | Transcription Factors - agonists | Pregnane X Receptor | Research Design | Cytochrome P-450 CYP2B6 | Index Medicus | Research Papers
Journal Article
The Plant Cell, ISSN 1040-4651, 6/2009, Volume 21, Issue 6, pp. 1813 - 1829
Aliphatic glucosinolate biosynthesis is highly compartmentalized, requiring import of 2-keto acids or amino acids into chloroplasts for side chain elongation... 
Bile acids | Chloroplasts | Genes | Glucosinolates | Amino acids | Cultured cells | Biosynthesis | Fatty acids | Plastids | Plant cells | MUTANT | CHAIN ELONGATION PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | EXPRESSION CLONING | PLANT SCIENCES | CELL BIOLOGY | DEGRADATION-PRODUCTS | RESISTANCE | PLANTS | TRANSCRIPT | ACCUMULATION | AUXIN HOMEOSTASIS | SPECIALIST | Histone Acetyltransferases | Flowers - metabolism | Transcriptional Activation | Phylogeny | Keto Acids - metabolism | Organic Anion Transporters, Sodium-Dependent - genetics | Arabidopsis Proteins - metabolism | Plastids - metabolism | Plant Leaves - drug effects | Arabidopsis Proteins - genetics | Arabidopsis Proteins - physiology | Arabidopsis - drug effects | Organic Anion Transporters, Sodium-Dependent - physiology | Cyclopentanes - pharmacology | Chloroplasts - metabolism | Arabidopsis - metabolism | Arabidopsis - genetics | Glucosinolates - biosynthesis | Transcription Factors - metabolism | Gene Expression Regulation, Plant - drug effects | Plant Leaves - genetics | Plant Leaves - metabolism | Oxylipins - pharmacology | Cytosol - metabolism | Acetates - pharmacology | Flowers - drug effects | Flowers - genetics | Organic Anion Transporters, Sodium-Dependent - metabolism | Arabidopsis thaliana | Plant molecular genetics | Physiological aspects | Genetic aspects | Chemical properties | DNA binding proteins | Research | Plant metabolites | Index Medicus
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 2006, Volume 1763, Issue 12, pp. 1427 - 1440
Peroxisomes play an important role in the biosynthesis of bile acids because a peroxisomal β-oxidation step is required for the formation of the mature C -bile... 
C 27-bile acid intermediates | Peroxisomal β-oxidation | Nuclear receptors | Peroxisome deficiency disorders | bile acid intermediates
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2018, Volume 41, Issue 4, pp. 597 - 603
Unusual bile acids (1β-hydroxylated bile acids), particularly 1β-hydroxyl-cholic acid (CA-1β-ol) and 1β-hydroxyl-chenodeoxycholic acid (CDCA-1β-ol), have been... 
CYP3A | 1β-hydroxylated bile acid | LC/tandem mass spectrometry (MS/MS) | 1 beta-hydroxylated bile acid | BIOLOGICAL-FLUIDS | IDENTIFICATION | NEWBORNS | MASS-SPECTROMETRY | CHILDREN | METABOLISM | DEVELOPMENTAL PATTERN | ENZYMES | URINE | PHARMACOLOGY & PHARMACY | FETAL LIVER | Index Medicus
Journal Article
Journal of Translational Medicine, ISSN 1479-5876, 01/2017, Volume 15, Issue 1, pp. 13 - 13
Background: The gastrointestinal motility is affected by gut microbiota and the relationship between them has become a hot topic. However, mechanisms of... 
Bile acids | Antibiotics | Serotonin | Gut motility | Intestinal microbiota | MEDICINE, RESEARCH & EXPERIMENTAL | CONSTIPATION | TRANSIT | RECOGNITION | 5-HYDROXYTRYPTAMINE | GUT MICROBIOTA | TRACT | SMOOTH-MUSCLE | CONTRACTION | GASTROINTESTINAL MOTILITY | BILE-ACIDS | Motility | Microbiota (Symbiotic organisms) | Gastrointestinal system | Research | Index Medicus
Journal Article
Genes and Development, ISSN 0890-9369, 07/2003, Volume 17, Issue 13, pp. 1581 - 1591
The nuclear bile acid receptor FXR has been proposed to play a central role in the feedback repression of the gene encoding cholesterol 7alpha-hydroxylase... 
Fibroblast growth factor | FXR | CYP7A1 | Bile acid | JNK | RAT HEPATOCYTES | bile acid | NEGATIVE FEEDBACK-REGULATION | SALT EXPORT PUMP | N-TERMINAL KINASE | DEVELOPMENTAL BIOLOGY | ORPHAN NUCLEAR RECEPTOR | RESPONSIVE ELEMENT | CELL BIOLOGY | fibroblast growth factor | GENETICS & HEREDITY | RETINOID-X-RECEPTOR | CHOLESTEROL 7-ALPHA-HYDROXYLASE GENE | TRANSCRIPTIONAL REGULATION | TRANSGENIC MICE | Phosphorylation | Humans | Fibroblast Growth Factors - genetics | Hepatocytes - metabolism | Receptors, Cytoplasmic and Nuclear | DNA-Binding Proteins - metabolism | Fibroblast Growth Factors - metabolism | Transfection | DNA-Binding Proteins - agonists | Chenodeoxycholic Acid - pharmacology | JNK Mitogen-Activated Protein Kinases | Cell Line | Bile Acids and Salts - biosynthesis | Response Elements | Signal Transduction | Cells, Cultured | Gene Expression Regulation | Fibroblast Growth Factors - pharmacology | Recombinant Proteins - pharmacology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Anthracenes - pharmacology | Isoxazoles - pharmacology | Transcription Factors - metabolism | Cholesterol 7-alpha-Hydroxylase - genetics | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Cholesterol 7-alpha-Hydroxylase - metabolism | Proto-Oncogene Proteins c-jun - metabolism | Mice | Transcription Factors - agonists | Enzyme Repression | Mitogen-Activated Protein Kinases - metabolism | Bile acids | Analysis | Physiological aspects | Genetic research | Genetic aspects | Biosynthesis | Gene expression | Growth factors | Cholesterol | Index Medicus | Research Papers
Journal Article