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1. Full Text Pathobiology of biliary epithelia
by Cheung, Angela C and Lorenzo Pisarello, Maria J and LaRusso, Nicholas F
BBA - Molecular Basis of Disease, ISSN 0925-4439, 04/2018, Volume 1864, Issue 4, pp. 1220 - 1231
Cholangiocytes are epithelial cells that line the intra- and extrahepatic biliary tree. They serve predominantly to mediate the content of luminal biliary... 
Senescence | Proliferation | Cholangiopathies | Apoptosis | Bile | Cholangiocytes | CHOLANGIOCYTE PRIMARY CILIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTRAHEPATIC BILE-DUCTS | INHIBITS HEPATIC CYSTOGENESIS | BDL RATS | CELLULAR SENESCENCE | HIGH-DENSITY-LIPOPROTEIN | BIOPHYSICS | GLUCAGON-LIKE PEPTIDE-1 | GENE-EXPRESSION | GROWTH-FACTOR | RECEPTOR AGONIST | Epithelial Cells - metabolism | Humans | Cell Proliferation - physiology | Bile Ducts - physiopathology | Cellular Senescence - physiology | Bile - metabolism | Bile Acids and Salts - metabolism | Epithelial Cells - pathology | MicroRNAs - metabolism | Cilia - metabolism | Bile Ducts - cytology | Animals | Bile Duct Diseases - physiopathology | Signal Transduction - physiology | Apoptosis - physiology | Epithelial Cells - cytology
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2. Biliary and pancreatic ductal epithelia
: pathobiology and pathophysiology
by Longnecker, Daniel S and Sirica, Alphonse E
1997, Gastroenterology and hepatology, ISBN 0824794141, Volume 3, ix, 575
Biliary tract | Pathophysiology | Epithelial cells | Bile ducts | Pancreatic duct
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3. Full Text The cholangiopathies: Disorders of biliary epithelia
by Lazaridis, Konstantinos N and Strazzabosco, Mario and LaRusso, Nicholas F
Gastroenterology, ISSN 0016-5085, 2004, Volume 127, Issue 5, pp. 1565 - 1577
(a ) Division of Gastroenterology, Ospedali Riuniti di Bergamo, Bergamo, Italy 
POLYCYSTIC KIDNEY-DISEASE | HEPATOCYTE GROWTH-FACTOR | CRYPTOSPORIDIUM-PARVUM | NITRIC-OXIDE | LIVER-DISEASE | RAT CHOLANGIOCYTES | KNOCKOUT MICE | GASTROENTEROLOGY & HEPATOLOGY | CHOLANGIOCARCINOMA CELL-LINE | BILE-ACIDS | CHOLANGIOCYTE PROLIFERATION | Animals | Models, Biological | Humans | Bile Ducts, Intrahepatic | Epithelial Cells - pathology | Bile Duct Diseases - classification | Bile Duct Diseases - pathology | Apoptosis | Nitrogen oxide | Platelet-derived growth factor | Transforming growth factors | Gastrointestinal diseases
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4. Full Text Tuft Cells-Systemically Dispersed Sensory Epithelia Integrating Immune and Neural Circuitry
by O'Leary, Claire E and Schneider, Christoph and Locksley, Richard M
Annual Review of Immunology, ISSN 0732-0582, 4/2019, Volume 37, Issue 1, pp. 47 - 72
Tuft cells-rare solitary chemosensory cells in mucosal epithelia-are undergoing intense scientific scrutiny fueled by recent discovery of unsuspected... 
IL-25 | TRPM5 | POU2F3 | type 2 immunity | tuft cells | chemosensation | STEM-CELLS | DOUBLECORTIN | BILE-DUCT | DISTINCT | BRUSH CELLS | ALPHA-GUSTDUCIN | TASTE RECEPTOR-CELLS | IMMUNOLOGY | TYPE-2 IMMUNITY | CHOLINERGIC CHEMOSENSORY CELLS | BITTER | Neural circuitry
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5. Full Text The dynamic biliary epithelia: Molecules, pathways, and disease
by O’Hara, Steven P and Tabibian, James H and Splinter, Patrick L and LaRusso, Nicholas F
Journal of Hepatology, ISSN 0168-8278, 2012, Volume 58, Issue 3, pp. 575 - 582
Summary Cholangiocytes, the cells lining bile ducts, are a heterogenous, highly dynamic population of epithelial cells. While these cells comprise a small... 
Gastroenterology and Hepatology | Reactivity | Cholangiopathy | Repair | Cholangiocytes | Biliary | SMALL BILE-DUCTS | CELLS | CRYPTOSPORIDIUM-PARVUM | CELLULAR SENESCENCE | HEDGEHOG | IMMUNE-RESPONSES | TOLL-LIKE RECEPTORS | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | PRIMARY SCLEROSING CHOLANGITIS | Epithelial Cells - physiology | Biliary Tract - cytology | Bile Duct Diseases - etiology | Humans | Cystic Fibrosis Transmembrane Conductance Regulator - physiology | Toll-Like Receptors - physiology | Bile Duct Diseases - pathology | Oligomers | Histocompatibility antigens | MicroRNA | Gastrointestinal diseases | Genomics | HLA histocompatibility antigens | Genetic research | Cystic fibrosis | Ursodiol | Liver cirrhosis | Mitogens
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6. Full Text The deleterious interplay between tumor epithelia and stroma in cholangiocarcinoma
by Cadamuro, Massimiliano and Stecca, Tommaso and Brivio, Simone and Mariotti, Valeria and Fiorotto, Romina and Spirli, Carlo and Strazzabosco, Mario and Fabris, Luca
BBA - Molecular Basis of Disease, ISSN 0925-4439, 04/2018, Volume 1864, Issue 4, pp. 1435 - 1443
Prognosis of cholangiocarcinoma, a devastating liver epithelial malignancy characterized by early invasiveness, remains very dismal, though its incidence has... 
Cancer-associated fibroblasts | Extracellular matrix | Tumor desmoplasia | Lymphatic endothelial cells | Tumor-associated macrophages | LYSYL OXIDASE | INTRAHEPATIC CHOLANGIOCARCINOMA | STEM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MESENCHYMAL TRANSITION | HEPATIC STELLATE CELLS | BIOPHYSICS | LIVER | LYMPHANGIOGENESIS | GROWTH-FACTOR | EXPRESSION | Epithelial Cells - metabolism | Paracrine Communication | Signal Transduction | Stromal Cells - pathology | Humans | Stromal Cells - metabolism | Extracellular Matrix - metabolism | Tumor Microenvironment | Epithelial Cells - pathology | Bile Ducts - cytology | Cell Hypoxia | Cholangiocarcinoma - pathology | Lymphatic Vessels - metabolism | Animals | Neoplasm Invasiveness - pathology | Lymphatic Vessels - pathology | Bile Duct Neoplasms - pathology | Extracellular Matrix - pathology | Bile Ducts - pathology | Disease Models, Animal
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7. Full Text The pathobiology of biliary epithelia
by Alpini, Gianfranco and McGill, James M and LaRusso, Nicholas F
Hepatology, ISSN 0270-9139, 2002, Volume 35, Issue 5, pp. 1256 - 1268
The morbidity and mortality from chronic biliary diseases (i.e., the cholangiopathies) remains substantial. End‐stage liver disease from biliary causes of... 
RAT-LIVER | CHOLANGIOCYTES | CELLS | PROTEIN-KINASE | CIRRHOSIS | PROLIFERATION | GROWTH-FACTOR | SECRETION | GASTROENTEROLOGY & HEPATOLOGY | CELLULAR-LOCALIZATION | ACID TRANSPORTER | Animals | Epithelial Cells - metabolism | Bile Duct Diseases - metabolism | Bile Ducts - metabolism | Humans | Epithelial Cells - pathology | Bile Duct Diseases - pathology | Bile Ducts - pathology
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8. Full Text Breast tumor kinase/protein tyrosine kinase 6 (Brk/PTK6) activity in normal and neoplastic biliary epithelia
by Mizuguchi, Yoshiaki and Specht, Susan and Isse, Kumiko and Sasatomi, Eizaburo and Lunz, John G and Takizawa, Toshihiro and Demetris, Anthony J
Journal of Hepatology, ISSN 0168-8278, 2015, Volume 63, Issue 2, pp. 399 - 407
Background & Aims Breast tumor kinase (BRK) augments proliferation and promotes cell survival in breast cancers via interactions with SH2 and SH3... 
Gastroenterology and Hepatology | SAM68 | RNA interference | ErbB2 | Tyrosine kinases | Cholangiocarcinoma (CC) | BRK | EGFR | CHOLANGIOCARCINOMA | LOCALIZATION | CYCLOOXYGENASE-2 | CANCER CELLS | SRC | THERAPEUTIC TARGET | GENE FAMILY | GROWTH-FACTOR | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | Bile Ducts, Intrahepatic - pathology | Cell Proliferation | Bile Duct Neoplasms - metabolism | Signal Transduction | Neoplasm Proteins - biosynthesis | Humans | Gene Expression Regulation, Neoplastic | Male | Blotting, Western | RNA, Neoplasm | Protein-Tyrosine Kinases - genetics | Bile Ducts, Intrahepatic - metabolism | Cell Line, Tumor | Female | Cell Differentiation | Bile Duct Neoplasms - genetics | Bile Duct Neoplasms - pathology | Neoplasm Proteins - genetics | Protein-Tyrosine Kinases - biosynthesis | Real-Time Polymerase Chain Reaction | Proteins | Antimitotic agents | Tyrosine | Phenols | Breast cancer | Antineoplastic agents
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9. Full Text Calcium signaling and the secretory activity of bile duct epithelia
by Amaya, Maria Jimena and Nathanson, Michael H
Cell Calcium, ISSN 0143-4160, 2014, Volume 55, Issue 6, pp. 317 - 324
Abstract Cytosolic calcium (Cai2+ ) is a second messenger that is important for the regulation of secretion in many types of tissues. Bile duct epithelial... 
Advanced Basic Science | Calcium | Secretion | InsP3 receptors | Cholangiocytes | PANCREATIC ACINAR-CELLS | PURINERGIC REGULATION | ISOLATED RAT HEPATOCYTES | BILIARY EPITHELIUM | INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR | III INSP RECEPTOR | TAUROURSODEOXYCHOLIC ACID | CELL BIOLOGY | HEPATOCYTE GAP-JUNCTIONS | ADENOSINE-TRIPHOSPHATE RELEASE | BICARBONATE SECRETION | Cholestasis - pathology | Epithelial Cells - secretion | Epithelial Cells - metabolism | Cholestasis - metabolism | Calcium - metabolism | Inositol 1,4,5-Trisphosphate Receptors - metabolism | Humans | Epithelial Cells - cytology | Calcium Signaling | Bile Ducts - cytology | Receptors, Cytoplasmic and Nuclear - metabolism | Carbonates
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10. Full Text Functional crosstalk between the adenosine transporter CNT3 and purinergic receptors in the biliary epithelia
by Godoy, Valeria and Banales, Jesús M and Medina, Juan F and Pastor-Anglada, Marçal
Journal of Hepatology, ISSN 0168-8278, 2014, Volume 61, Issue 6, pp. 1337 - 1343
Background & Aims Both hepatocytes and cholangiocytes release ATP into the bile, where it acts as a potent autocrine/paracrine stimulus that activates biliary... 
Gastroenterology and Hepatology | Nucleoside transporters | Adenosine | Purinergic signalling | Cholangiocytes | CELLS | CHOLANGIOCYTE PRIMARY CILIA | AIRWAY EPITHELIA | RELEASE | RAT CHOLANGIOCYTES | NUCLEOTIDES | GASTROENTEROLOGY & HEPATOLOGY | ATP | EXPRESSION | BICARBONATE SECRETION | BILE | Receptors, Purinergic - physiology | Cells, Cultured | Rats | Receptor, Adenosine A2A - physiology | Cyclic AMP Response Element-Binding Protein - physiology | Receptor Cross-Talk - physiology | Membrane Transport Proteins - physiology | Bile Ducts - cytology | Bile Ducts - physiology | Cyclic AMP - physiology | Epithelial Cells - physiology | Cyclic AMP-Dependent Protein Kinases - physiology | Animals | Models, Animal | Epithelial Cells - cytology | Extracellular Signal-Regulated MAP Kinases - physiology
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11. Full Text Cellular and humoral autoimmunity directed at bile duct epithelia in murine biliary atresia
by Mack, Cara L and Tucker, Rebecca M and Lu, Brandy R and Sokol, Ronald J and Fontenot, Andrew P and Ueno, Yoshiyuki and Gill, Ronald G
Hepatology, ISSN 0270-9139, 11/2006, Volume 44, Issue 5, pp. 1231 - 1239
Biliary atresia is an inflammatory fibrosclerosing lesion of the bile ducts that leads to biliary cirrhosis and is the most frequent indication for liver... 
IN-VITRO | NOD MICE | OBSTRUCTION | INFANTS | DISEASE | CD4(+) | PROLIFERATION | HLA | GASTROENTEROLOGY & HEPATOLOGY | T-CELLS | IMMUNOHISTOCHEMISTRY | Biliary Atresia - etiology | T-Lymphocytes - physiology | Rotavirus | Biliary Atresia - immunology | Autoantigens - blood | Adoptive Transfer | Interferon-gamma - metabolism | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | CD4-Positive T-Lymphocytes - physiology | Biliary Atresia - pathology | Autoimmunity - physiology | Epithelium - immunology | Animals | CD3 Complex - immunology | Female | Mice | Mice, Inbred BALB C | In Vitro Techniques | Bile Ducts - immunology | Bile Ducts - pathology | Disease Models, Animal
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