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JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 07/2017, Volume 60, Issue 14, pp. 5969 - 5989
Several reports have recently emerged regarding the identification of heteroarylsulfonamides as Na(V)1.7 inhibitors that demonstrate high levels of selectivity... 
TARGET | RAT BILIARY-EXCRETION | IN-VITRO | CHEMISTRY, MEDICINAL | DRUG DISCOVERY | RECEPTOR PXR | SCN9A | VALIDATION | BIOACTIVATION | PAIN DISORDERS | EXPRESSION
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 07/2017, Volume 60, Issue 14, pp. 5990 - 6017
Because of its strong genetic validation, Na(V)1.7 has attracted significant interest as a target for the treatment of pain. We have previously reported on a... 
MOLECULAR-MECHANISM | INACTIVATION | FIBRILLATION | RAT BILIARY-EXCRETION | NEUROPATHIC PAIN | ERYTHROMELALGIA | CHEMISTRY, MEDICINAL | DRUG DISCOVERY | EXTREME PAIN DISORDER | MUTATIONS | ANTAGONISTS
Journal Article
HAEMATOLOGICA, ISSN 0390-6078, 03/2019, Volume 104, Issue 4, pp. 678 - 689
The current paradigm in the field of mammalian iron biology states that body iron levels are determined by dietary iron absorption, not by iron excretion. Iron... 
OVERLOAD | TRANSFERRIN-BOUND IRON | HOMEOSTASIS | BILIARY-EXCRETION | BILE-FLOW | RATS | COPPER | ABSORPTION | BETA-THALASSEMIA | HEMATOLOGY | HEMOCHROMATOSIS
Journal Article
Toxicological Sciences, ISSN 1096-6080, 12/2017, Volume 160, Issue 2, pp. 351 - 360
Fibrates and their receptor, namely peroxisome proliferator-activated receptor α (PPARα), have been reported to regulate bile acid (BA) synthesis and... 
biliary excretion | PPARα | bile acids | PPARα-MEDIATED REDUCTION OF BILE ACIDS BY CLOFIBRATE
Journal Article
Journal of dietary supplements, ISSN 1939-0211, 12/2018, pp. 1 - 15
Although biliary excretion is one of the biological elimination processes for foreign compounds, intake of high-protein diets was hypothesized to enhance their... 
toxicokinetics | N-nitrosodiethylamine | nitrite | biliary excretion | dietary proteins
Journal Article
Journal Article
Journal Article
Toxicological Sciences, ISSN 1096-6080, 03/2019, Volume 168, Issue 1, pp. 110 - 125
Abstract Liver and skeletal muscle-specific microRNAs (miRNAs) are currently being evaluated as novel plasma biomarkers that may out-perform or add value to... 
CIRCULATING MICRORNAS | APOPTOSIS | DILI | liver | CHOLESTASIS | miR-1 | PROLIFERATION | TOXICITY | biomarker | IDENTIFICATION | miR-206 | BIOMARKERS | miR-122 | miR-133 | BILIARY-EXCRETION | TOXICOLOGY | skeletal muscle | miR-192 | CLINICAL-SIGNIFICANCE | Dili
Journal Article
Toxicological Sciences, ISSN 1096-6080, 12/2010, Volume 118, Issue 2, pp. 485 - 500
Journal Article
Toxicological Sciences, ISSN 1096-6080, 12/2017, Volume 160, Issue 2, pp. 351 - 360
Fibrates and their receptor, namely peroxisome proliferator-activated receptor alpha (PPAR alpha), have been reported to regulate bile acid (BA) synthesis and... 
Biliary excretion | PPARα | Bile acids | PPAR alpha | FATTY-ACIDS | INDUCTION | ACTIVATED-RECEPTOR-ALPHA | biliary excretion | GENE | METABOLISM | bile acids | PROLIFERATOR | TISSUE DISTRIBUTION | TOXICOLOGY | CHOLESTEROL 7-ALPHA-HYDROXYLASE | EXPRESSION | BEZAFIBRATE
Journal Article
by Zhai, QX and Liu, Y and Wang, C and Zhao, JX and Zhang, H and Tian, FW and Lee, YK and Chen, W
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, ISSN 0021-8561, 04/2019, Volume 67, Issue 14, pp. 3956 - 3965
The heavy metal cadmium (Cd) is a contaminant widely distributed in the food chain. In the present study, 8 week oral administration of a probiotic strain,... 
BILE-ACID | Lactobacillus plantarum | bile acid | TRANSPORTERS | ENZYME INDUCERS | FOOD SCIENCE & TECHNOLOGY | gut microbiota | METABOLISM | INHABITANTS | GLUTATHIONE | BILIARY-EXCRETION | AGRICULTURE, MULTIDISCIPLINARY | URINARY CADMIUM | cadmium | BIOLOGICAL HALF-LIFE | ABSORPTION | CHEMISTRY, APPLIED | enterohepatic circulation | Index Medicus
Journal Article