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Cancer cell international, ISSN 1475-2867, 01/2019, Volume 19, Issue 1, pp. 226 - 226
BackgroundBridging integrator 1 (BIN1) has showed outstanding tumor-suppressive potential via inhibiting c-MYC-mediated tumorigenesis. However, a frequent... 
CDK5 | NSCLC | BIN1 | c-MYC
Journal Article
International Journal of Cancer, ISSN 0020-7136, 09/2015, Volume 137, Issue 5, pp. 1095 - 1106
Indoleamine 2,3‐dioxygenase (IDO) has been reported to be involved in esophageal squamous cell cancer (ESCC) progression by promoting immune escape. Previous... 
bridging integrator‐1 (Bin1) | indoleamine 2,3‐dioxygenase (IDO) | prognosis | esophageal squamous cell cancer (ESCC) | immuno‐editing | immuno-editing | indoleamine 2,3-dioxygenase (IDO) | bridging integrator-1 (Bin1) | TARGET | SUPPRESSION GENE BIN1 | MECHANISM | CONVERSION | INDOLEAMINE 2,3-DIOXYGENASE | METASTASES | C-MYC | indoleamine 2 | ONCOLOGY | PATHWAY | 3-dioxygenase (IDO) | T-CELLS | LYMPHOCYTES | Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Lymph Nodes - pathology | Prognosis | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Tumor Microenvironment | Male | Esophageal Neoplasms - pathology | Esophageal Neoplasms - metabolism | Lymphatic Metastasis - pathology | Tumor Suppressor Proteins - genetics | Adult | Female | Nuclear Proteins - genetics | Lymphocytes - metabolism | Tumor Suppressor Proteins - metabolism | Lymph Nodes - metabolism | Nuclear Proteins - metabolism | Esophageal Neoplasms - genetics | Adaptor Proteins, Signal Transducing - genetics | Aged | Adaptor Proteins, Signal Transducing - metabolism | Immunohistochemistry | Fc receptors | Analysis | Development and progression | T cells | Esophageal cancer | Tumors | Survival analysis | Lymphatic system | Medical prognosis | Index Medicus
Journal Article
Science Translational Medicine, ISSN 1946-6234, 2019, Volume 11, Issue 484, p. eaav1866
Centronuclear myopathies (CNMs) are severe diseases characterized by muscle weakness and myofiber atrophy. Currently, there are no approved treatments for... 
MEDICINE, RESEARCH & EXPERIMENTAL | MUTATIONS | BIN1 | EXPRESSION | CELL BIOLOGY
Journal Article
EMBO reports, ISSN 1469-221X, 11/2017, Volume 18, Issue 11, pp. 2051 - 2066
Endocytic processes are facilitated by both curvature‐generating BAR ‐domain proteins and the coordinated polymerization of actin filaments. Under... 
protein Bin1 | tau | BAR | Alzheimer's disease | actin binding | genetic risk factor | N-BAR protein Bin1 | PROTEIN | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CROSS-LINKING | FILAMENT TURNOVER | TAU PATHOLOGY | CELL BIOLOGY | SKELETAL-MUSCLE | STRUCTURAL BASIS | SYNAPTIC VESICLE ENDOCYTOSIS | MEMBRANE CURVATURE | SH3 DOMAIN | Tauopathies - genetics | Humans | Actins - metabolism | Tauopathies - pathology | tau Proteins - metabolism | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Actins - genetics | Drosophila melanogaster - metabolism | Protein Isoforms - metabolism | tau Proteins - genetics | Tumor Suppressor Proteins - genetics | Cloning, Molecular | Escherichia coli - metabolism | Protein Interaction Domains and Motifs | Nuclear Proteins - genetics | Binding Sites | Actin Cytoskeleton - genetics | Disease Models, Animal | Recombinant Proteins - metabolism | Gene Expression | Tumor Suppressor Proteins - metabolism | Actin Cytoskeleton - metabolism | Genetic Vectors - chemistry | Gene Expression Regulation | Genetic Vectors - metabolism | Nuclear Proteins - metabolism | Recombinant Proteins - genetics | Transcription Factors - genetics | Transcription Factors - metabolism | Carrier Proteins - genetics | Tauopathies - metabolism | Animals | Carrier Proteins - metabolism | Escherichia coli - genetics | Adaptor Proteins, Signal Transducing - genetics | Protein Binding | Drosophila Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | Protein Isoforms - genetics | Membranes | Neurodegenerative diseases | Drosophila | Health risks | Polymerization | Rods | Bundles | Risk factors | Membrane proteins | Bundling | Proteins | Depolymerization | Insects | Tau protein | Filaments | Neurodegeneration | Actin | Isoforms | BAR protein | Cytoskeleton | Alzheimers disease | Curvature | Index Medicus | N‐BAR protein Bin1 | Neuroscience | Cell Adhesion, Polarity & Cytoskeleton
Journal Article
Lung Cancer, ISSN 0169-5002, 04/2019, Volume 130, pp. 35 - 41
A number of key immune regulators show prognostic value in malignant pleural mesothelioma (MPM), but the association between Bridging integrator 1 (BIN1),... 
Prognosis | Tumor infiltrating lymphocytes | BIN1 | Biomarkers | PD-L1 | Mesothelioma | Macrophages | IDO1 | IMMUNE CELLS | SUPPRESSOR BIN1 | INDOLEAMINE 2,3-DIOXYGENASE | INHIBITION | ONCOLOGY | IMMUNOTHERAPY | RESPIRATORY SYSTEM | INFLAMMATION | T-CELLS | PROGRESSION | CANCER-IMMUNITY | Immunohistochemistry | Lymphocytes | Analysis | Tumors
Journal Article
Journal Article
Journal Article
Frontiers in Aging Neuroscience, ISSN 1663-4365, 2015, Volume 7, Issue MAY, pp. 99 - 99
Journal Article
Circulation Research, ISSN 0009-7330, 06/2017, Volume 120, Issue 12, pp. 1846 - 1848
Journal Article
by Wang, J and Jia, Y and Zhao, S and Zhang, X and Wang, X and Han, X and Wang, Y and Ma, M and Shi, J and Liu, L
Oncogene, ISSN 0950-9232, 11/2017, Volume 36, Issue 45, pp. 6235 - 6243
Non-small cell lung cancer (NSCLC) is one of the most common and malignant carcinoma worldwide, and the incidence and mortality are increasing rapidly.... 
TUMOR-SUPPRESSOR BIN1 | APOPTOSIS | ACTIVATION | PD-L1 EXPRESSION | INFILTRATING LYMPHOCYTES | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | EGFR | CELL BIOLOGY | ONCOLOGY | DOWNSTREAM | INTEGRATOR 1 BIN1 | GENETICS & HEREDITY | UP-REGULATION | Tumor Escape | Prognosis | Humans | Lung Neoplasms - pathology | Genes, myc | MAP Kinase Signaling System - immunology | Heterografts | Transfection | Adaptor Proteins, Signal Transducing - immunology | Mitogen-Activated Protein Kinases - immunology | Carcinoma, Non-Small-Cell Lung - pathology | Receptor, Epidermal Growth Factor - immunology | Lung Neoplasms - enzymology | Proto-Oncogene Proteins c-myc - immunology | Nuclear Proteins - immunology | B7-H1 Antigen - immunology | Tumor Suppressor Proteins - immunology | Carcinoma, Non-Small-Cell Lung - immunology | Lung Neoplasms - immunology | Animals | Mice, Nude | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Proto-Oncogene Proteins c-myc - genetics | Carcinoma, Non-Small-Cell Lung - enzymology | Care and treatment | Carrier proteins | Development and progression | Genetic aspects | Cellular signal transduction | Lung cancer, Non-small cell | Health aspects | Fibroblast growth factor 2 | Lymphatic system | Epidermal growth factor receptors | Tumor-infiltrating lymphocytes | Lung cancer | c-Myc protein | Non-small cell lung carcinoma | MAP kinase | Metastasis | Myc protein | Kinases | Lymph nodes | Metastases | Signal transduction | Molecular modelling | Protein kinase | Lymphocytes | Immunotherapy | PD-L1 protein | Apoptosis | Lymph | Index Medicus
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 3/2017, Volume 54, Issue 2, pp. 1419 - 1428
Recent genome-wide association studies have identified an association between the bridging integrator 1 gene (BIN1) rs744373 polymorphism and late-onset... 
Neurology | Neurosciences | Biomedicine | Alzheimer’s disease | BIN1 | Neurobiology | rs744373 | Cell Biology | Meta-analysis
Journal Article
Journal Article