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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2011, Volume 108, Issue 49, pp. 19719 - 19724
Four members of the mammalian ATP binding cassette (ABC) transporter G subfamily are thought to be involved in transmembrane (TM) transport of sterols. The... 
ATP binding cassette transporters | COS cells | Sterols | Plasmids | HDL lipoproteins | Amino acids | Cell membranes | Repression | Cholesterols | Endosomes | 27-hydroxycholesterol | 25-hydroxycholesterol | Cholesterol | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | ATHEROSCLEROSIS | MEMBRANE-PROTEIN | PLASMA-MEMBRANE | HIGH-DENSITY-LIPOPROTEIN | SENSING DOMAIN | cholesterol | SCAP | CELLULAR CHOLESTEROL EFFLUX | ENDOPLASMIC-RETICULUM | ACCUMULATION | Sterols - metabolism | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Cricetulus | Lipoproteins - genetics | Humans | Cercopithecus aethiops | Molecular Sequence Data | Macrophages, Peritoneal - cytology | Endosomes - metabolism | Transfection | ATP-Binding Cassette Transporters - genetics | Biological Transport | HEK293 Cells | Lipoproteins - metabolism | ATP-Binding Cassette Transporters - metabolism | Sterol Regulatory Element Binding Protein 2 - metabolism | Macrophages, Peritoneal - drug effects | CHO Cells | Amino Acid Sequence | Cricetinae | Cells, Cultured | Blotting, Western | Sequence Homology, Amino Acid | Animals | Intracellular Space - metabolism | Benzoates - pharmacology | Mutation | Macrophages, Peritoneal - metabolism | Benzylamines - pharmacology | COS Cells | Research | Properties | Adenosine triphosphate | Protein binding | Proteins | Membranes | ABC transporters | Cells | Steroids | Index Medicus | Biological Sciences
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2014, Volume 111, Issue 25, pp. 9145 - 9150
Journal Article
Biochemical Journal, ISSN 0264-6021, 2014, Volume 461, Issue 2, pp. 269 - 278
ABC (ATP-binding-cassette) transporters carry out many vital functions and are involved in numerous diseases, but study of the structure and function of these... 
Nanodisc | Polymer | Membrane protein | Detergent | Purification | Solubilization | polymer | TRYPTOPHAN | WILD-TYPE | TRANSLOCATION | solubilization | BIOCHEMISTRY & MOLECULAR BIOLOGY | detergent | FLUORESCENCE | purification | nanodisc | membrane protein | MULTIDRUG-RESISTANCE PROTEIN-1 | MEMBRANE-PROTEINS | MOLECULAR-BASIS | RECONSTITUTION | RESIDUES | P-GLYCOPROTEIN REVEALS | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Humans | Polystyrenes - chemistry | Recombinant Proteins - isolation & purification | ATP-Binding Cassette Transporters - chemistry | Cloning, Molecular | ATP-Binding Cassette, Sub-Family B, Member 1 - chemistry | Protein Stability | Multidrug Resistance-Associated Proteins - chemistry | Recombinant Proteins - chemistry | Neoplasm Proteins - chemistry | Maleates - chemistry | Cystic Fibrosis Transmembrane Conductance Regulator - chemistry | ATP-Binding Cassette Transporters - isolation & purification | Cystic Fibrosis Transmembrane Conductance Regulator - isolation & purification | Animals | Neoplasm Proteins - isolation & purification | Protein Binding | Ligands | Protein Conformation | ATP Binding Cassette Transporter, Sub-Family B | Mice | Kinetics | Multidrug Resistance-Associated Proteins - isolation & purification | ATP-Binding Cassette, Sub-Family B, Member 1 - isolation & purification | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2013, Volume 110, Issue 24, pp. 9710 - 9715
ABCB10 is one of the three ATP-binding cassette (ABC) transporters found in the inner membrane of mitochondria. In mammals ABCB10 is essential for... 
ATP binding cassette transporters | Proteins | Crystals | Adenosine triphosphatases | Lipids | Nucleotides | Exporters | Binding sites | Monomers | Crystal structure | X-ray crystallography | Nucleotide complex | Abc mitochondrial erythroid | Cardiolipin | Human membrane protein structure | COMPLEX | nucleotide complex | MECHANISM | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | MITOCHONDRIA | HYDROLYSIS | cardiolipin | ABC mitochondrial erythroid | P-GLYCOPROTEIN | MITOFERRIN-1 | RESISTANCE | human membrane protein structure | PROTEINS | REVEALS | Humans | Molecular Conformation | Molecular Sequence Data | Crystallography, X-Ray | Nucleotides - chemistry | ATP-Binding Cassette Transporters - chemistry | Sf9 Cells | ATP-Binding Cassette Transporters - genetics | Adenosine Triphosphate - metabolism | ATP-Binding Cassette Transporters - metabolism | Protein Structure, Tertiary | Amino Acid Sequence | Adenosine Triphosphatases - metabolism | Models, Molecular | Binding Sites - genetics | Phosphatidylcholines - chemistry | Nucleotides - metabolism | Molecular Dynamics Simulation | Sequence Homology, Amino Acid | Animals | Protein Binding | Adenosine Triphosphatases - chemistry | Adenosine Triphosphatases - genetics | Lipid Bilayers - chemistry | Lipid Bilayers - metabolism | Mutation | Adenosine Triphosphate - chemistry | Phosphatidylethanolamines - chemistry | Biological transport, Active | Physiological aspects | Research | Binding proteins | Structure | Health aspects | Adenosine triphosphate | Oxidative stress | Mitochondria | ABC transporters | Index Medicus | Biological Sciences
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2014, Volume 289, Issue 34, pp. 23264 - 23274
Journal Article
Philosophical Transactions of the Royal Society B: Biological Sciences, ISSN 0962-8436, 01/2009, Volume 364, Issue 1514, pp. 239 - 245
Journal Article
Atherosclerosis, ISSN 0021-9150, 2014, Volume 236, Issue 1, pp. 215 - 226
Journal Article
Journal Article
Science, ISSN 0036-8075, 6/2010, Volume 328, Issue 5986, pp. 1689 - 1693
Elevated leukocyte cell numbers (leukocytosis), and monocytes in particular, promote atherosclerosis; however, how they become increased is poorly understood.... 
Myeloid cells | Leukocytosis | Transgenic animals | HDL lipoproteins | REPORTS | Atherosclerosis | Transgenes | Macrophages | Lesions | Cholesterols | Progenitor cells | CHOLESTEROL | MULTIDISCIPLINARY SCIENCES | MACROPHAGE ABCA1 | LIPID RAFTS | GENE-EXPRESSION | ATHEROSCLEROSIS | MICE | ACCUMULATION | ABCG1 | HIGH-DENSITY-LIPOPROTEIN | APOLIPOPROTEIN-A-I | Cell Proliferation | Lipoproteins - genetics | Lipoproteins, HDL - metabolism | Apolipoprotein A-I - genetics | Leukocytosis - metabolism | ATP-Binding Cassette Transporters - genetics | Atherosclerosis - therapy | Leukocytosis - therapy | Myeloproliferative Disorders - metabolism | Bone Marrow Transplantation | Leukocytosis - physiopathology | Lipoproteins - metabolism | ATP-Binding Cassette Transporters - metabolism | Hematopoietic Stem Cells - physiology | Mice, Inbred DBA | ATP Binding Cassette Transporter 1 | Multipotent Stem Cells - physiology | ATP Binding Cassette Transporter, Subfamily G, Member 1 | Myeloproliferative Disorders - therapy | Signal Transduction | Atherosclerosis - physiopathology | Mice, Inbred C57BL | Cells, Cultured | Mice, Transgenic | Receptors, Interleukin-3 - metabolism | Apolipoprotein A-I - metabolism | Cholesterol - metabolism | Atherosclerosis - metabolism | Macrophages - metabolism | Phenotype | Animals | Myeloid Progenitor Cells - physiology | Myeloproliferative Disorders - physiopathology | Mice | Hypercholesterolemia - metabolism | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Cell proliferation | High density lipoproteins | Physiological aspects | Development and progression | Research | Health aspects | Hematopoietic stem cells | Adenosine triphosphate | Index Medicus
Journal Article