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Journal Article
Journal Article
Chemical Communications, ISSN 1359-7345, 05/2014, Volume 50, Issue 40, pp. 5373 - 5375
The aggregation of amyloid-beta protein (1-42) is studied at experimental concentrations using all-atom molecular dynamics simulations. We observe a fast... 
A-BETA-42 | PEPTIDES | A-BETA(1-40) | ALZHEIMERS-DISEASE | SIMULATIONS | CHEMISTRY, MULTIDISCIPLINARY | OLIGOMERS | Humans | Protein Multimerization | Models, Molecular | Protein Binding | Protein Conformation | Amyloid beta-Peptides - chemistry | Molecular Dynamics Simulation | Index Medicus
Journal Article
Brain Research, ISSN 0006-8993, 05/2019, Volume 1710, p. 125
The prion protein (PrP) is known to bind certain soluble aggregates of the amyloid [beta]-protein (A[beta]), and two regions of PrP, one centered around... 
Viral antibodies | Nervous system diseases | Neurons | Prions | Imaging systems | Amyloid beta-protein | Antibodies | Protein binding
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 05/2015, Volume 112, Issue 20, pp. 6497 - 6502
Kv7.4 channels are a crucial determinant of arterial diameter both at rest and in response to endogenous vasodilators. However, nothing is known about the... 
CELLS | GENE-RELATED PEPTIDE | POTASSIUM CHANNELS | MULTIDISCIPLINARY SCIENCES | REACTIVITY | K(V)7 CHANNELS | vascular biology | Kv7 channels | GATED K+ CHANNEL | KCNQ genes | SMOOTH-MUSCLE | electrophysiology | G-protein beta gamma subunits | HYPERTENSION | EXPRESSION | BINDING
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 08/2016, Volume 36, Issue 35, pp. 9041 - 9056
Journal Article
BIOCHEMISTRY, ISSN 0006-2960, 04/2014, Volume 53, Issue 14, pp. 2329 - 2343
Journal Article
by Li, X and Xie, BL and Dong, XY and Sun, Y
LANGMUIR, ISSN 0743-7463, 05/2018, Volume 34, Issue 17, pp. 5106 - 5115
Aggregation of amyloid beta-proteins (A beta) mediated by metal ions such as Zn2+ has been suggested to be implicated in the progression of Alzheimer's disease... 
MULTIFUNCTIONALITY | ALZHEIMERS-DISEASE | STABILITY | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | PATHOLOGY | FIBRILLOGENESIS | ACIDULATED SERUM-ALBUMIN | CHEMISTRY, MULTIDISCIPLINARY | PEPTIDE | NANOPARTICLES | BINDING | INSIGHTS
Journal Article
NEURON, ISSN 0896-6273, 06/2014, Volume 82, Issue 5, pp. 1032 - 1044
Activation of K+ channels by the G protein beta gamma subunits is an important signaling mechanism of G-protein-coupled receptors. Typically,... 
RECTIFYING POTASSIUM CHANNELS | MUSCARINIC K+ CHANNEL | PYRAMIDAL NEURONS | ATRIAL MYOCYTES | HETEROTRIMERIC G-PROTEINS | SHORT-TERM DESENSITIZATION | RAT NEOCORTEX | GIRK CURRENTS | GTP-BINDING PROTEINS | RGS PROTEINS | NEUROSCIENCES
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2006, Volume 281, Issue 21, pp. 14776 - 14786
We showed previously that cells expressing wild-type (WT) beta-amyloid precursor protein (APP) or coexpressing WTAPP and WT presenilin (PS) 1/2 produced APP... 
Protein Structure, Tertiary | Cricetinae | Amyloid beta-Protein Precursor - chemistry | Endopeptidases - chemistry | Peptide Fragments - chemistry | Animals | Membrane Proteins - chemistry | Amyloid Precursor Protein Secretases | Protein Binding | Amyloid beta-Peptides - chemistry | Kinetics | Mutation | CHO Cells | Index Medicus
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 01/2017, Volume 140, Issue 2, p. 210
  The neuropathology of Alzheimer's disease (AD) includes amyloid plaque formation by the amyloid [beta]-protein (A[beta]) and intracellular paired helical... 
Oligomers | Development and progression | Alzheimer's disease | Amyloid beta-protein | Protein binding | Proteins | Neurochemistry | Tomography | Alzheimers disease
Journal Article
Cytokine, ISSN 1043-4666, 04/2017, Volume 92, p. 24
* Cebpb.sup.-/- mice are resistant to EAE. * In vivo Th17 responses are impaired in absence of C/EBP[beta]. * Th17 differentiation is normal in APC-free... 
Protein binding | Autoimmunity | Dendritic cells | T cells
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2013, Volume 190, Issue 7, pp. 3466 - 3479
Journal Article