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Nature, ISSN 0028-0836, 07/2015, Volume 523, Issue 7561, pp. 481 - 485
Although CRISPR-Cas9 nucleases are widely used for genome editing(1,2), the range of sequences that Cas9 can recognize is constrained by the need for a... 
ENDONUCLEASE | RECOGNITION | DUAL-RNA | MULTIDISCIPLINARY SCIENCES | CAS9 | CLEAVAGE | DIRECTED EVOLUTION | Mutagenesis | Plasmids | Genes | Genetic engineering | Genomes | Mutation | Experiments | Binding sites | Index Medicus
Journal Article
Nature Methods, ISSN 1548-7091, 09/2011, Volume 8, Issue 9, pp. 765 - 772
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 11, pp. e13928 - e13928
Background: Alzheimers disease (AD) has been strongly linked to an anomalous self-assembly of the amyloid-beta peptide (A beta). The correlation between... 
TRAUMATIC BRAIN-INJURY | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | A-BETA | LONG-TERM POTENTIATION | PROTEIN-PRECURSOR | MONOCLONAL-ANTIBODIES | MEMORY LOSS | PEPTIDE | TRANSGENIC MICE | Surface Plasmon Resonance | Epitope Mapping | Amyloid beta-Peptides - pharmacology | Humans | Protein Multimerization | Antibody Affinity - immunology | Peptide Fragments - pharmacology | Immunoglobulin M - immunology | Amyloid - metabolism | Peptide Fragments - immunology | Female | Antibodies, Monoclonal - immunology | Cell Survival - drug effects | Enzyme-Linked Immunosorbent Assay | Antibodies, Monoclonal - pharmacology | Antibodies, Anti-Idiotypic - immunology | Cell Survival - immunology | Protein Binding - immunology | Autoantibodies - immunology | Peptide Fragments - chemistry | Animals | Amyloid - immunology | Cell Line, Tumor | Amyloid beta-Peptides - immunology | Mice | Mice, Inbred BALB C | Amyloid beta-Peptides - chemistry | Antibodies, Monoclonal - metabolism | Immunoglobulin M | Self assembly | Animal models | Peptides | Memory | Antibodies | Cytotoxicity | Biochemistry | Selectivity | Kinases | Monomers | Proteins | Oligomers | Immunology | Alzheimer's disease | Immunization | Immunological memory | Immunoglobulins | Autoantibodies | Neurodegenerative diseases | Pathological effects | Biophysics | Epitopes | Self-assembly | β-Amyloid | Avidity | Dimers | Kinetics | Alzheimers disease | Binding sites | Animal cognition | Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinsk bioteknologi | Biokemi | Medical Biochemistry | MEDICINE | Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) | Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci) | Medical Biotechnology | Chemistry | MEDICIN | Kemi | medicinsk biokemi
Journal Article