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Science, ISSN 0036-8075, 12/2014, Volume 346, Issue 6215, pp. 1370 - 1373
Stochasticity inherent to biochemical reactions (intrinsic noise) and variability in cellular states (extrinsic noise) degrade information transmitted through... 
CELLS | MODULE | ROBUSTNESS | NEGATIVE FEEDBACK | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | Physiological aspects | Protein research | Extracellular matrix | Cellular signal transduction | Research | Phosphotransferases | Signal transduction | Chemical reactions | Biochemistry | Cellular biology | Degradation | Networks | Cellular | Noise | Dynamics | Kinases | Human behavior
Journal Article
Bioinformatics, ISSN 1367-4803, 12/2018, Volume 34, Issue 23, pp. 4079 - 4086
Abstract Motivation Intracellular signalling is realized by complex signalling networks, which are almost impossible to understand without network models,... 
ACTIVATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CANCER | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | ERK | Index Medicus
Journal Article
by Rusk, N
NATURE METHODS, ISSN 1548-7091, 11/2015, Volume 12, Issue 11, pp. 1013 - 1013
Journal Article
Current Opinion in Biotechnology, ISSN 0958-1669, 2006, Volume 17, Issue 4, pp. 406 - 414
Journal Article
BioEssays, ISSN 0265-9247, 12/2002, Volume 24, Issue 12, pp. 1110 - 1117
Biochemical networks, including those containing signaling pathways, display a wide range of regulatory properties. These include the ability to propagate... 
PROTEIN-KINASE-C | ACTIVATES RAF-1 | INHIBITION | PHOSPHORYLATION | MAP KINASE | BIOCHEMICAL PATHWAYS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGY | SYSTEMS | CASCADE | CELL | GOOD EGG | Animals | Signal Transduction | Time Factors | Models, Biological | Computer Simulation | Humans | Cellular signal transduction | Models | Neural networks | Computational biology
Journal Article
Current Opinion in Biotechnology, ISSN 0958-1669, 2010, Volume 21, Issue 4, pp. 551 - 555
Apoptosis is a complex but highly defined cellular program of cell demolition. Apoptosis can be triggered by the extrinsic or the intrinsic death pathways.... 
Internal Medicine | BCL-2 | DOMAIN | PROTEIN | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMICAL RESEARCH METHODS | IAP | DEATH | MODEL | INHIBITOR | CASPASE ACTIVATION | CELL | LIFE | Models, Theoretical | Signal Transduction | Systems Biology | Humans | Apoptosis | Analysis
Journal Article
Nature Communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, p. 5811
Epidermal growth factor receptor (EGFR) overexpression plays an important oncogenic role in cancer. Regular EGFR protein levels are increased in cancer cells... 
AUTOCRINE LOOP | RECEPTOR TYROSINE KINASES | MULTIDISCIPLINARY SCIENCES | EPIDERMAL-GROWTH-FACTOR | GENE-EXPRESSION | HUMAN GLIOMAS | CANCER-THERAPY | TRANSGENIC MICE | INNATE IMMUNITY | BRAIN-TUMORS | FACTOR-ALPHA | Receptor, Epidermal Growth Factor - genetics | Shc Signaling Adaptor Proteins - metabolism | Apoptosis - drug effects | Humans | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | Extracellular Signal-Regulated MAP Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Interferon Regulatory Factor-3 - genetics | Brain Neoplasms - metabolism | Proto-Oncogene Proteins c-akt - genetics | Receptor, Epidermal Growth Factor - metabolism | Glioblastoma - genetics | Glioblastoma - metabolism | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Protein-Serine-Threonine Kinases - metabolism | Membrane Proteins - genetics | Protein-Serine-Threonine Kinases - genetics | Brain Neoplasms - genetics | Signal Transduction - genetics | TNF-Related Apoptosis-Inducing Ligand - metabolism | Carrier Proteins - genetics | Carrier Proteins - metabolism | Shc Signaling Adaptor Proteins - genetics | Glioblastoma - pathology | Cell Line, Tumor | Interferon Regulatory Factor-3 - metabolism | Epidermal Growth Factor - pharmacology | Primary Cell Culture | TNF-Related Apoptosis-Inducing Ligand - genetics
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